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Displaying drugs 851 - 875 of 9081 in total
Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe. It is used to treat hyperparathyroidism due to parathyroid tumours or renal failure.
Approved
Matched Synonyms: … (R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethane amine ... N-((1R)-1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine …
Matched Iupac: … [(1R)-1-(naphthalen-1-yl)ethyl]({3-[3-(trifluoromethyl)phenyl]propyl})amine …
Matched Salts cas: … 364782-34-3
Matched Products: … CETCAL® 60 ... MIMPARA® 60 MG ... CINACRED 60 MG TABLETAS …
Etoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic...
Approved
Investigational
Matched Synonyms: … 5-chloro-2-(6-methylpyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine ... 5-Chloro-3-(4-methanesulfonyl-phenyl)-6'-methyl-[2,3']bipyridinyl ... 5-chloro-6'-methyl-3-(p-(methylsulfonyl)phenyl)-2,3'-bipyridine …
Matched Iupac: … 5-chloro-3-(4-methanesulfonylphenyl)-6'-methyl-2,3'-bipyridine …
Matched Description: … It is approved in more than 60 countries worldwide but not in the US. …
Matched Salts cas: … 202409-40-3
Matched Products: … ETROBAX 60 FILM COATED TABLETS 60 MG ... Etrobax 60 (Etoricoxib Tablets 60 mg) ... SIKSTOP 60
Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. Because of its ability to cause serious toxicity and possibly death, amiodarone...
Approved
Investigational
Matched Synonyms: … 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran ... 2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuran ... 2-Butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone …
Matched Iupac: … {2-[4-(2-butyl-1-benzofuran-3-carbonyl)-2,6-diiodophenoxy]ethyl}diethylamine …
Matched Products: … AMIODARONA 150 MG/ 3 ML ... CORDARONE INJECTION 150 mg/3 ml ... AMIODARONA CLORHIDRATO 150 MG/3 ML …
Famotidine is a competitive histamine-2 (H2) receptor antagonist that works to inhibit gastric acid secretion. It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children. Compared to other H2 receptor antagonists, famotidine displays high selectivity towards...
Approved
Matched Synonyms: … N-Sulfamoyl-3-((2-guanidinothiazol-4-yl)methylthio)propionamide ... (1-Amino-3-(((2-((diaminomethylene)amino)-4-thiazolyl)methyl)thio)propylidene)sulfamide ... 3-(((2-((Aminoiminomethyl)amino)-4-thiazolyl)methyl)thio)-N-(aminosulfonyl)propanimidamide …
Matched Iupac: … 3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]-N'-sulfamoylpropanimidamide …
Matched Products: … KLINOTAL POLVO X 40 MG / 3 ML ... GASTIFAM 40 MG TABLET, 60 ADET ... NEVOFAM 20 MG TABLET, 60 ADET …
Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder. It has since received approval for a...
Approved
Matched Synonyms: … (3S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine …
Matched Iupac: … methyl[(3S)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl]amine …
Matched Products: … DULOXTA 60 ... ALACIR® 60 ... CYMBALTA (60 MG) …
Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis.[A3811, A260880, L40968] Abiraterone was first approved by the FDA and EMA on April, July, and September 2011, respectively. It is used to treat metastatic...
Approved
Matched Synonyms: … (3β)-17-(pyridin-3-yl)androsta-5,16-dien-3-ol ... 17-(3-Pyridyl)androsta-5,16-dien-3beta-ol …
Matched Iupac: … (3aS,3bR,7S,9aR,9bS,11aS)-9a,11a-dimethyl-1-(pyridin-3-yl)-3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H, …
Matched Products: … RATEBİR 250 MG TABLET, 60 ADET ... ABYGA 500 MG FİLM KAPLI TABLET, 60 ADET ... ZYTİGA 500 MG FİLM KAPLI TABLET, 60 ADET …
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Approved
Matched Synonyms: … 3-(N-methylpyrollidino)pyridine ... (S)-3-(1-methylpyrrolidin-2-yl)pyridine ... 3-(2-(N-methylpyrrolidinyl))pyridine …
Matched Iupac: … 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine …
Matched Salts cas: … 6019-06-3
Matched Products: … ETAPA 3 ... Habitrol Step 3 ... NICOTINE Transdermal System Step 3
Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Approved
Vet approved
Matched Synonyms: … 3-Benzoylhydratropic acid ... 2-(3-Benzoylphenyl)propionic acid ... 3-Benzoyl-α-methylbenzeneacetic acid …
Matched Iupac: … 2-(3-benzoylphenyl)propanoic acid …
Matched Products: … VANIKET %2.5 JEL,60 G ... PROFENID %2.5 JEL, 60 G …
Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment. Chlorthalidone improves blood pressure and swelling by preventing water absorption from the kidneys through inhibition of the Na+/Cl− symporter in the distal convoluted tubule...
Approved
Matched Synonyms: … 1-keto-3-(3'-sulfamyl-4'-chlorophenyl)-3-hydroxyisoindoline ... 1-oxo-3-(3-sulfamyl-4-chlorophenyl)-3-hydroxyisoindoline ... 3-hydroxy-3-(4-chloro-3-sulfamylphenyl)phthalimidine …
Matched Iupac: … 2-chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzene-1-sulfonamide …
A histamine H2 agonist used clinically to test gastric secretory function.
Approved
Matched Synonyms: … 1H-pyrazole-3-ethanamine ... 3-(2-aminoethyl)pyrazole ... 2-(3-pyrazolyl)ethylamine …
Iloperidone is a benzisoxazole and an atypical antipsychotic agent that was first approved by the FDA on May 6, 2009. It is considered to be a second-generation antipsychotic drug with multiple receptor binding profile, although it shows high affinity towards 5-HT2A and dopamine D2 receptors. Iloperidone is currently used to...
Approved
Matched Synonyms: … 1-[4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1- piperidinyl]propoxy]-3-methoxyphenyl]ethanone ... 4'-(3-(4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidino)propoxy)-3'-methoxyacetophenone …
Matched Iupac: … 1-(4-{3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy}-3-methoxyphenyl)ethan-1-one …
Cinnamaldehyde is a naturally occurring flavonoid that gives the spice cinnamon its flavour and odour. It occurs naturally in the bark of cinnamon trees and other species of the genus Cinnamomum such as camphor and cassia. Sensitivity to cinnamaldehyde may be identified with a clinical patch test.
Approved
Experimental
Matched Synonyms: … (E)-3-Phenylpropenal ... (E)-3-Phenyl-propenal ... (3E)-3-phenylprop-2-enal …
Matched Iupac: … (2E)-3-phenylprop-2-enal …
Vinblastine derivative with antineoplastic activity against cancer. Major side effects are myelosuppression and neurotoxicity. Vindesine is used extensively in chemotherapy protocols (antineoplastic combined chemotherapy protocols).
Approved
Investigational
Matched Synonyms: … 3-carbamoyl-4-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine ... 3-(aminocarbonyl)-O4-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine …
The 3-cyclopentyl ether of ethinyl estradiol.
Approved
Matched Synonyms: … Estradiol-17-beta 3-cyclopentyl ether ... 17-alpha-Ethinylestradiol 3-cyclopentyl ether ... 17alpha-Ethynylestradiol 3-cyclopentyl ether …
Matched Description: … The 3-cyclopentyl ether of ethinyl estradiol. …
A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
Approved
Matched Synonyms: … (3-hydroxyphenyl)dimethylethylammonium ... 3-hydroxy-N,N-dimethyl-N-ethylanilinium ... N-ethyl-3-hydroxy-N,N-dimethylanilinium …
Matched Iupac: … N-ethyl-3-hydroxy-N,N-dimethylanilinium …
Ticagrelor, or AZD6140, was first described in the literature in 2003.[A204170,A2903] Ticagrelor is an ADP derivative developed for its P2Y12 receptor antagonism. Unlike clopidogrel, ticagrelor is not a prodrug. It is marketed by Astra Zeneca as Brilinta in the US and Brilique or Possia in the EU, . Ticagrelor was...
Approved
Matched Synonyms: … (4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol ... (1S,2S,3R,5S)-3-(7-((1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-(1,2,3)triazolo …
Matched Iupac: … [4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol ... (1S,2S,3R,5S)-3-(7-{[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino}-5-(propylsulfanyl)-3H-[1,2,3]triazolo …
Matched Description: … Ticagrelor was granted EMA approval on 3 December 2010. …
Matched Products: … RECLOVAC 60 (Ticagrelor Film-coated Tablets 60 mg) ... TICAGREL 60 ... BRILINTA® 60 MG …
Zimelidine has been banned worldwide due to serious, sometimes fatal, cases of central and/or peripheral neuropathy known as Guillain-Barré syndrome and due to a peculiar hypersensitivity reaction involving many organs including skin exanthema, flu-like symptoms, arthralgias, and sometimes eosinophilia. Additionally, zimelidine was charged to cause an increase in suicidal ideation...
Approved
Withdrawn
Matched Synonyms: … (Z)-3-(4'-Bromophenyl)-3-(3''-pyridyl)dimethylallylamine …
Matched Iupac: … [(2Z)-3-(4-bromophenyl)-3-(pyridin-3-yl)prop-2-en-1-yl]dimethylamine …
Nepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) usually sold as a prescription eye drop. It is used to treat pain and inflammation associated with cataract surgery.
Approved
Investigational
Matched Synonyms: … 2-amino-3-benzoylbenzeneacetamide …
Matched Iupac: … 2-(2-amino-3-benzoylphenyl)acetamide …
Matched Products: … NEVANAC 3 MG/ML GÖZ DAMLASI, SÜSPANSİYON …
Methyl nicotinate is the methyl ester of DB00627 that is used as an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and joint pain. The action of methyl nicotinate as a rubefacient is thought to involve peripheral vasodilation. For veterinary purposes, methyl nicotinate is used to...
Approved
Matched Synonyms: … 3-(Carbomethoxy)pyridine ... 3-(Methoxycarbonyl)pyridine ... Methyl 3-pyridinecarboxylate …
Matched Iupac: … methyl pyridine-3-carboxylate …
Testosterone is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism.[L8983,L8935,L8938,L8986,L8989,L8992,L8995] Testosterone antagonizes the androgen receptor to induce gene expression that causes the growth and development of masculine sex organs and secondary sexual characteristics.[A187114,L8983,L8935,L8938,L8986,L8989,L8992,L8995] Testosterone was isolated from samples and also synthesized in 1935.
Approved
Investigational
Matched Synonyms: … 4-androsten-17β-ol-3-one ... 17beta-hydroxy-4-androsten-3-one …
Matched Categories: … 3-Oxoandrosten (4) Derivatives …
Matched Products: … TOSTRAN %2 JEL, 60 G …
Zonisamide is a sulfonamide anticonvulsant used as an adjunctive therapy in adults with partial-onset seizures.[L42530,L42535] Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels, leading to a reduction of T-type calcium channel currents or by binding allosterically to GABA receptors. This latter action may inhibit the uptake of...
Approved
Investigational
Matched Synonyms: … 1,2-Benzisoxazole-3-methanesulfonamide ... 3-(Sulfamoylmethyl)-1,2-benzisoxazole ... Benzo[d]isoxazol-3-yl-methanesulfonamide …
Matched Iupac: … (1,2-benzoxazol-3-yl)methanesulfonamide …
Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline structure. While it is isolated from the bark of Picea sitchensis or Polygonum cuspidatum, polydatin may be detected in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products and many daily diets...
Approved
Matched Synonyms: … trans-resveratrol 3-β-glucoside ... resveratrol-3-O-b-mono-D-glucoside ... trans-resveratrol 3-β-D-glucoside …
Matched Iupac: … (2S,3R,4S,5S,6R)-2-{3-hydroxy-5-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenoxy}-6-(hydroxymethyl)oxane-3,4,5 …
Prochlorperazine, also known as compazine, is a piperazine phenothiazine and first-generation antipsychotic drug that is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia.[label] It mainly works by depressing the chemoreceptor trigger zone and blocking...
Approved
Vet approved
Matched Synonyms: … 3-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine ... Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine ... 3-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine …
Matched Iupac: … 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Chronic venous insufficiency is a common condition the western population. Compression and pharmacotherapy are frequently used to manage chronic venous insufficiency, improving circulation and symptoms of venous disease. Diosmin is a bioflavonoid isolated from various plants or synthesized from hesperidin. It is used for the improvement of capillary fragility or...
Approved
Investigational
Matched Synonyms: … 3',5,7-trihydroxy-4'-methoxyflavone-7-rutinoside ... 3',5,7-trihydroxy-4'-methoxyflavone 7-rhamnoglucoside …
Matched Iupac: … 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5 …
Matched Mixtures name: … DIOKERN 450 MG/50 MG FILM KAPLI TABLET,60 ADET ... VARIDOS 450 MG/50 MG FILM KAPLI TABLET, 60 ADET …
Matched Products: … DAFLON 500 MG FILM TABLET, 60 ADET …
Cabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome. Cabergoline possesses potent agonist activity on dopamine D2 receptors.
Approved
Matched Synonyms: … 1-((6-allylergolin-8β-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea ... 1-ethyl-3-(3'-dimethylamionpropyl)-2-(6'-allylergoline-8'β-carbonyl)urea ... 1-[(6-allylergoline-8β-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea …
Matched Iupac: … 1-[3-(dimethylamino)propyl]-3-ethyl-1-[(2R,4R,7R)-6-(prop-2-en-1-yl)-6,11-diazatetracyclo[7.6.1.0^{2,7 …
Displaying drugs 851 - 875 of 9081 in total