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Displaying drugs 851 - 875 of 1087 in total
Terazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and hypertension[FDA Label] . Terazosin blocks adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and the prostate .
Approved
Matched Description: … quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and ... adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and
Matched Salts name: … Terazosin hydrochloride ... Terazosin hydrochloride hydrate …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … Terazosin Hydrochloride ... Terazosin hydrochloride ... Terazosin Hydrochloride Anhydrous …
Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.
Approved
Matched Mixtures name: … Perphenazine and Amitriptyline Hydrochloride ... Perphenazine and Amitriptyline Hydrochloride ... Chlordiazepoxide and Amitriptyline Hydrochloride
Matched Salts name: … Amitriptyline hydrochloride
Matched Categories: … amitriptyline and psycholeptics ... Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … Amitriptyline Hydrochloride ... Amitriptyline hydrochloride ... AMITRIPTYLINE HYDROCHLORIDE
A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is...
Approved
Matched Description: … of myasthenia and as a fluorescent probe in HPLC. ... (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment …
Matched Salts name: … Guanidine hydrochloride
Matched Products: … Guanidine hydrochloride
A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
Approved
Vet approved
Matched Description: … Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the ... A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. …
Matched Salts name: … Tolazoline hydrochloride
Matched Categories: … Topical Products for Joint and Muscular Pain …
Matched Products: … Priscoline hydrochloride
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear,...
Approved
Investigational
Matched Description: … It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, ... mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and
Matched Salts name: … Papaverine hydrochloride
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Papaverine and Derivatives …
Matched Products: … Papaverine Hydrochloride ... PAPAVERINE HYDROCHLORIDE ... Papaverine Hydrochloride Injection USP …
Tiagabine is an anti-convulsive medication. It is also used in the treatment for panic disorder as are a few other anticonvulsants. Though the exact mechanism by which tiagabine exerts its effect on the human body is unknown, it does appear to operate as a selective GABA reuptake inhibitor.
Approved
Investigational
Matched Salts name: … Tiagabine hydrochloride
Matched Categories: … Nipecotic Acid and Derivatives …
Matched Products: … Tiagabine Hydrochloride
A short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.
Approved
Illicit
Matched Description: … A short-acting opioid anesthetic and analgesic derivative of fentanyl. ... It produces an early peak analgesic effect and fast recovery of consciousness. ... effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and
Matched Salts name: … Alfentanil hydrochloride
Matched Categories: … Fentanyl and fentanyl analogues …
Matched Products: … Alfentanil Hydrochloride
Reboxetine is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD. Its mesylate (i.e. methanesulfonate) salt is sold under tradenames including Edronax, Norebox, Prolift, Solvex, Davedax or Vestra. Reboxetine has two chiral centers, but it only exists as two enantiomers, (R,R)-(-)- and (S,S)-(+)-reboxetine.
Approved
Experimental
Matched International brands: … Prolift
Matched Description: … Reboxetine is an antidepressant drug used in the treatment of clinical depression, panic disorder and ... Reboxetine has two chiral centers, but it only exists as two enantiomers, (R,R)-(-)- and (S,S)-(+)-reboxetine ... Its mesylate (i.e. methanesulfonate) salt is sold under tradenames including Edronax, Norebox, Prolift
Naratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. It is typically used for the treatment of migraine headaches.
Approved
Investigational
Matched Salts name: … Naratriptan hydrochloride
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … Naratriptan Hydrochloride
A sympathomimetic agent with properties similar to dextroamphetamine. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)
Approved
Illicit
Matched Salts name: … Benzphetamine hydrochloride
Matched Products: … Benzphetamine Hydrochloride
Colesevelam is a bile acid sequestrant. Colesevelam is used with exercise and diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in the blood. It works by binding bile acids in the intestine. Bile acids are made when cholesterol is broken...
Approved
Matched Description: … Colesevelam is used with exercise and diet changes (restriction of cholesterol and fat intake) to reduce ... the amount of cholesterol and certain fatty substances in the blood. …
Matched Salts name: … Colesevelam hydrochloride
Matched Products: … Colesevelam Hydrochloride ... Colesevelam hydrochloride
Sotalol is a methanesulfonanilide developed in 1960. It was the first of the class III anti arrhythmic drugs. Sotalol was first approved as an oral tablet on 30 October 1992. A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous injection indicated for life threatening...
Approved
Matched Description: … [L6334] A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous ... injection indicated for life threatening ventricular arrhythmias and maintaining normal sinus rhythm …
Matched Salts name: … Sotalol hydrochloride
Matched Categories: … Beta Blocking Agents and Thiazides ... Beta Blocking Agents, Non-Selective, and Thiazides ... sotalol and thiazides ... sotalol and acetylsalicylic acid …
Matched Products: … Sotalol Hydrochloride ... Sotalol hydrochloride ... Sotalol Hydrochloride AF …
A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
Approved
Vet approved
Matched Salts name: … Doxapram hydrochloride
Matched Products: … Doxapram Hydrochloride
Sirpiglenastat, also known as DRP-104, is a prodrug of 6-diazo-5-oxo-L-norleucine (DON), which is a broad-acting glutamine antagonist. It is under investigation in clinical trial NCT04471415 (Study to Investigate DRP-104 in Adults With Advanced Solid Tumors).
Investigational
Matched Synonyms: … L-norleucine, n-acetyl-l-tryptophyl-6-diazo-5-oxo-, 1-methylethyl ester ... Propan-2-yl (2s)-2-((n-acetyl-l-tryptophyl)amino)-6-diazo-5-oxohexanoate …
A tetracycline analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.
Approved
Matched Description: … A tetracycline analog having a 7-chloro and a 6-methyl. …
Matched Salts name: … Demeclocycline hydrochloride
Matched Products: … Demeclocycline Hydrochloride
Dextropropoxyphene is an opioid analgesic manufactured by Eli Lilly and Company. It is used in the symptomatic treatment of mild pain. It displays antitussive and local anaesthetic actions. Due to the risk of cardiac arrhythmias and overdose, possibly leading to death, dextropropoxyphene has been withdrawn from the market in Europe...
Approved
Illicit
Investigational
Withdrawn
Matched Description: … Dextropropoxyphene is an opioid analgesic manufactured by Eli Lilly and Company. ... It displays antitussive and local anaesthetic actions. ... been withdrawn from the market in Europe and the United States. …
Matched Mixtures name: … Propoxyphene Hydrochloride and Acetaminophen ... Propoxyphene Hydrochloride and Acetaminophen ... Propoxyphene Hydrochloride and Acetaminophen …
Matched Salts name: … Dextropropoxyphene hydrochloride
Matched Products: … Propoxyphene Hydrochloride
Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decreased...
Approved
Withdrawn
Matched Description: … It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate ... Esmolol prevents the action of two naturally occurring substances: epinephrine and norepinephrine. ... FDA withdrew its approval for the use of all parenteral dosage form drug products containing esmolol hydrochloride
Matched Salts name: … Esmolol hydrochloride
Matched Products: … Esmolol Hydrochloride ... Esmolol Hydrochloride in Water ... Esmolol Hydrochloride In Sodium Chloride …
Experimental
Matched Name: … 3-(1,10-Phenanthrol-2-Yl)-L-Alanine
Experimental
Matched Name: … D-naphthyl-1-acetamido boronic acid alanine
Experimental
Matched Name: … L-naphthyl-1-acetamido boronic acid alanine
Etoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic...
Approved
Investigational
Matched Description: … of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and
Matched Salts name: … Etoricoxib hydrochloride
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … PROKIN-X. ... PROKIN-X® ... PROKIN-X. 120 …
Experimental
Matched Synonyms: … 3-(oxidosulfanyl)-L-alanine
Apitegromab is under investigation in clinical trial NCT03921528 (An Active Treatment Study of SRK-015 in Patients With Type 2 or Type 3 Spinal Muscular Atrophy).
Investigational
Matched Synonyms: … Immunoglobulin g4 (234-proline), anti-(human progrowth differentiation factor 8) (human monoclonal srk …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ligufalimab is a humanized immunoglobulin G4 (IgG4) monoclonal antibody targeting leukocyte surface antigen CD47. It is under investigation in clinical trial NCT04900350 (A Trial of AK117 (Anti-cd47) in Patients With Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … Immunoglobulin g4 (225-proline), anti-(human cd47 antigen) (human-mus musculus monoclonal ak117 .gamma …
Bepranemab is a recombinant humanized Igg4P monoclonal antibody directed against human Tau.
Investigational
Matched Synonyms: … Immunoglobulin g4 (226-proline), anti-(human tau protein) (human-rattus norvegicus monoclonal ucb0107 …
Displaying drugs 851 - 875 of 1087 in total