Displaying drugs 876 - 900 of 1287 in total
XL019
XL019 is a selective inhibitor of the cytoplasmic tyrosine kinase JAK2. An IND for XL019 was filed by Exelixis in May 2007.
Investigational
Matched Description: … XL019 is a selective inhibitor of the cytoplasmic tyrosine kinase JAK2. …
Oxfenicine
Oxfenicine in an inhibitor of myocardial metabolism of nonesterified fatty acids (NEFA).
Experimental
Matched Description: … Oxfenicine in an inhibitor of myocardial metabolism of nonesterified fatty acids (NEFA). …
Lisaftoclax
Lisaftoclax is a novel, orally active, selective and potent BCL-2 inhibitor
Investigational
Matched Description: … Lisaftoclax is a novel, orally active, selective and potent BCL-2 inhibitor …
Rolipram
A phosphodiesterase inhibitor with antidepressant properties.
Investigational
Matched Description: … A phosphodiesterase inhibitor with antidepressant properties. …
ABT-737
An inhibitor of members of the Bcl‑2 family of apoptosis regulators.
Investigational
Matched Description: … An inhibitor of members of the Bcl‑2 family of apoptosis regulators.[A252977] …
TNG908
TNG908 is a small molecule inhibitor of protein arginine methyl transferase 5 (PRMT5).
Investigational
Matched Description: … TNG908 is a small molecule inhibitor of protein arginine methyl transferase 5 (PRMT5). …
Adefovir
Investigational
Matched Categories: … Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor …
Telotristat
A tryptophan hydroxylase inhibitor. Telotristat ethyl (brand name Xermelo) is a prodrug of telotristat.
Experimental
Matched Description: … A tryptophan hydroxylase inhibitor. …
Matched Categories: … Tryptophan Hydroxylase Inhibitor …
Matched Categories: … Tryptophan Hydroxylase Inhibitor …
(R)-Rolipram
The (R)-enantiomer of rolipram, it is a phosphodiesterase inhibitor with antidepressant properties.
Experimental
Matched Description: … The (R)-enantiomer of rolipram, it is a phosphodiesterase inhibitor with antidepressant properties. …
N-chlorotaurine
N-chlorotaurine is an inhibitor of inducible nitric oxide synthase and IkappaB kinase.
Investigational
Matched Description: … N-chlorotaurine is an inhibitor of inducible nitric oxide synthase and IkappaB kinase. …
Basifungin
Basifungin, also known as aureuobacidin A, is a phosphorylceramide synthase inhibitor , .
Experimental
Matched Description: … Basifungin, also known as _aureuobacidin A_, is a phosphorylceramide synthase inhibitor [L2960], [A33381 …
JQ1
First-in-class potent and selective inhibitor of the BRD4 signaling pathway.
Investigational
Matched Description: … First-in-class potent and selective inhibitor of the BRD4 signaling pathway.[A252967] …
AKI-001
AKI-001 is an aurora kinase inhibitor.
Experimental
Matched Description: … AKI-001 is an aurora kinase inhibitor. …
7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline
Potent reversible inhibitor of phenylethanolamine N-methyltransferase.
Experimental
Matched Description: … Potent reversible inhibitor of phenylethanolamine N-methyltransferase. …
GBR-12783
A selective inhibitor of dopamine uptake.
Investigational
Matched Description: … A selective inhibitor of dopamine uptake.[A252997] …
Scriptaid
Scriptaid is a histone deacetylase (HDAC) inhibitor researched for its anti-tumor properties.
Investigational
Matched Description: … Scriptaid is a histone deacetylase (HDAC) inhibitor researched for its anti-tumor properties. …
EA-2353
EA-2353 is a small molecule inhibitor of kinase mediators of the Wnt pathway.
Investigational
Matched Description: … EA-2353 is a small molecule inhibitor of kinase mediators of the Wnt pathway. …
Irpagratinib
Irpagratinib (ABSK011) is a highly selective inhibitor of fibroblast growth factor receptor (FGFR) 4.
Investigational
Matched Description: … Irpagratinib (ABSK011) is a highly selective inhibitor of fibroblast growth factor receptor (FGFR) 4. …
Filanesib
Filanesib is a potent Kinesin Spindle Protein (KSP) inhibitor that caused marked tumor regression in preclinical models of human solid tumors and human leukemias, often leading to durable responses.
Investigational
Matched Description: … Filanesib is a potent Kinesin Spindle Protein (KSP) inhibitor that caused marked tumor regression in …
SF1126
SF1126 is an integrin-targeted PI3 kinase inhibitor.
Investigational
Matched Description: … SF1126 is an integrin-targeted PI3 kinase inhibitor. …
Concanamycin A
Concanamycin A is an H+-ATPase (vacuolar) inhibitor.
Experimental
Matched Description: … Concanamycin A is an H+-ATPase (vacuolar) inhibitor. …
Dacinostat
Dacinostat is a novel histone deacetylase inhibitor.
Investigational
Matched Description: … Dacinostat is a novel histone deacetylase inhibitor.[A253032] …
PHA-767491
PHA-767491 is a Cdc7/CDK9 inhibitor.
Investigational
Matched Description: … PHA-767491 is a Cdc7/CDK9 inhibitor.[A253077] …
Peficitinib
Peficitinib has been used in trials studying the treatment and basic science of Psoriasis, Pharmacodynamics, Drug Interactions, Colitis, Ulcerative, and RHEUMATOID ARTHRITIS, among others.
Investigational
Matched Categories: … Janus Kinase Inhibitor …
FT-1101
FT-1101 is a novel Bromodomain and Extra-Terminal motif (BET) inhibitor. FT-1101 is under investigation in clinical trial NCT02543879 (Study of a Novel BET Inhibitor FT-1101 in Patients With Relapsed or Refractory Hematologic Malignancies).
Investigational
Matched Description: … FT-1101 is a novel Bromodomain and Extra-Terminal motif (BET) inhibitor. ... [A257301] FT-1101 is under investigation in clinical trial NCT02543879 (Study of a Novel BET Inhibitor …
Displaying drugs 876 - 900 of 1287 in total