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Displaying drugs 926 - 950 of 1075 in total

Fluvoxamine

Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor. Though it is in the same class as other SSRI drugs, it is most often used to treat obsessive-compulsive disorder. Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised...
Approved
Investigational
Matched Description: … It was launched in the US in December 1994 and in Japan in June 1999. ... Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Matched Products: … LUVOX 50MG FILM COATED TABLET ... LUVOX 100MG FILM COATED TABLET ... REVOXIN 50MG FILM TABLET, 30 ADET …

Rifaximin

Rifaximin is a semisynthetic, rifamycin-based non-systemic antibiotic, meaning that the drug will not pass the gastrointestinal wall into the circulation as is common for other types of orally administered antibiotics. It has multiple indications and is used in treatment of traveller's diarrhea caused by E. coli; reduction in risk of...
Approved
Investigational
Matched Description: … It has multiple indications and is used in treatment of traveller's diarrhea caused by E. coli; reduction ... It is marketed under the brand name Xifaxan by Salix Pharmaceuticals. ... encephalopathy recurrence; as well as diarrhea-predominant irritable bowel syndrome (IBS-D) in adult women and …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … HEPAZEC 550 MG FILM TABLET,56-FILM-TABLET ... XIFAXAN Film-coated Tablet 550mg ... COLIDUR 200 MG FILM TABLET, 24 ADET …

Tamoxifen

Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations.[A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments.[L7799,L7802] Tamoxifen may no longer be the preferred treatment for these types of cancers...
Approved
Matched Description: … treatment for these types of cancers as patients generally have better survival, side effect profiles, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … NOLVADEX 10 MG FILM TABLET, 30 ADET ... NOLVADEX 10 MG FILM TABLET, 250 ADET ... TAMOXIT 20 MG FİLM KAPLI TABLET (TAMOFEN), 100 TABLET …

Dydrogesterone

A synthetic progestational hormone with no androgenic or estrogenic properties. Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit ovulation.
Approved
Investigational
Withdrawn
Matched Description: … Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does …
Matched Mixtures name: … Femoston Conti 1/5mg Film-Coated Tablet ... Femoston Conti 0.5mg/2.5mg Film Coated Tablet …
Matched Categories: … Genito Urinary System and Sex Hormones ... dydrogesterone and estrogen ... dydrogesterone and estrogen ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Progestogens and Estrogens, Sequential Preparations …
Matched Products: … DUPHASTON TABLET 10 mg (Film-coated) ... DUPHASTON 10 MG FİLM KAPLI TABLET, 20 ADET …

Siponimod

Siponimod, also known as Mayzent, by Novartis, is a new drug formulated for the management of Multiple Sclerosis (MS). It was approved by the FDA on March 26, 2019 and by Health Canada on February 20, 2020. This drug is considered a sphingosine-1-phosphate (S1P) receptor modulator and is thought to...
Approved
Investigational
Matched Description: … It was approved by the FDA on March 26, 2019 [L5792] and by Health Canada on February 20, 2020. ... , disrupting communication between the brain and other parts of the body. ... [L12171] This drug is considered a _sphingosine-1-phosphate (S1P) receptor modulator_ and is thought …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … MAYZENT FILM-COATED TABLET 2MG ... MAYZENT FILM-COATED TABLET 0.25MG …

Dobesilic acid

Experimental
Investigational
Matched Products: … DOXIUM 1000 MG FILM TABLET, 30 ADET ... DOXIUM 1000 MG FILM TABLET, 60 ADET ... MODET 1000 MG FILM KAPLI TABLET ,30 ADET …

Doravirine

Doravirine is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) intended to be administered in combination with other antiretroviral medicines.[L12729,L4562] Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and tenofovir disoproxil fumarate (300 mg). Doravirine is formally indicated for the treatment of...
Approved
Investigational
Matched Description: … Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and ... adult patients with no prior antiretroviral treatment experience, further expanding the possibility and …
Matched Mixtures name: … DELSTRIGO FILM COATED TABLET 100MG/300MG/300MG …
Matched Categories: … lamivudine, tenofovir disoproxil and doravirine …
Matched Products: … PIFELTRO FILM-COATED TABLET 100MG ... PİFELTRO 100 MG FİLM KAPLI TABLET, 30 ADET …

Diflunisal

Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs. Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. Though its mechanism of action has not been clearly established, most of its actions appear to be associated with inhibition of prostaglandin synthesis via the...
Approved
Investigational
Matched Description: … rheumatoid arthritis and osteoarthritis. ... Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. ... Diflunisal is used to relieve pain accompanied with inflammation and in the symptomatic treatment of …
Matched Categories: … Salicylic Acid and Derivatives …
Matched Products: … DOLPHIN 250 MG FILM TABLET, 10 TABLET ... DOLPHIN 250 MG FILM TABLET, 20 TABLET ... DOLPHIN 500 MG FILM TABLET, 10 TABLET …

Eplerenone

Eplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative regulatory feedback of aldosterone on renin secretion. The resulting increased plasma renin activity and aldosterone circulating levels do not overcome the effects of...
Approved
Matched Description: … antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and ... The resulting increased plasma renin activity and aldosterone circulating levels do not overcome the ... mineralocorticoid receptors relative to its binding to recombinant human glucocorticoid, progesterone and …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … INSPRA 25MG FILM-COATED TABLETS ... INSPRA 50MG FILM-COATED TABLETS ... EPLEDAY 25 MG FILM KAPLI TABLET, 50 ADET …

Lemborexant

Lemborexant is a novel dual orexin receptor antagonist used in the treatment of insomnia characterized by difficulties with sleep onset and/or sleep maintenance. Recent research in the field of sleep disorders has revealed that insomnia is likely driven not by the inability of the brain to "switch on" sleep-related circuits,...
Approved
Investigational
Matched Description: … receptors, lemborexant and other orexin antagonists (e.g. ... receptor antagonist used in the treatment of insomnia characterized by difficulties with sleep onset and ... [zopiclone], [zolpidem], benzodiazepines) focus on enhancing sleep drive via modulation of GABA and melatonin …
Matched Categories: … Hypnotics and Sedatives ... Sleep Initiation and Maintenance Disorders …
Matched Products: … DAYVIGO FILM-COATED TABLET 5MG ... DAYVIGO FILM-COATED TABLET 10MG …

Tolperisone

Tolperisone is an oral, centrally acting muscle relaxant. Its precise mechanism is not completely understood, though it blocks sodium and calcium channels. It possesses a high affinity for nervous system tissue, reaching highest concentrations in brain stem, spinal cord and peripheral nerves. Based on existing clinical data, Tolperisone is not...
Investigational
Matched Description: … Its precise mechanism is not completely understood, though it blocks sodium and calcium channels. ... high affinity for nervous system tissue, reaching highest concentrations in brain stem, spinal cord and ... Based on existing clinical data, Tolperisone is not sedating and does not interact with alcohol. …
Matched Categories: … Topical Products for Joint and Muscular Pain …
Matched Products: … Netolp 50 mg Film Kaplı Tablet, 30 ADET ... Netolp 150 mg Film Kaplı Tablet, 30 ADET ... TOLKİMADO 50 MG FİLM KAPLI TABLET, 30 ADET …

Tucatinib

Tucatinib is a kinase inhibitor drug used with trastuzumab and capecitabine in the treatment of unresectable or metastatic HER-2 positive breast cancer. It was developed by Seattle Genetics and approved by the FDA on April 17, 2020. Tucatinib is a promising new treatment for patients with metastatic breast cancer who...
Approved
Investigational
Matched Description: … It was developed by Seattle Genetics and approved by the FDA on April 17, 2020. ... Tucatinib is a kinase inhibitor drug used with [trastuzumab] and [capecitabine] in the treatment of unresectable ... [L12951] Tucatinib is a promising new treatment for patients with metastatic breast cancer who have not …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … TUKYSA (TUCATINIB) FILM-COATED TABLETS 150 mg ... TUKYSA (TUCATINIB) FILM-COATED TABLETS 50 mg …

Exemestane

Exemestane is an oral steroidal aromatase inhibitor used in the adjuvant treatment of hormonally-responsive (also called hormone-receptor-positive, estrogen-responsive) breast cancer in postmenopausal women. It irreversibly binds to the active site of the enzyme resulting in permanent inhibition.
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … FEMMEX 25 MG FILM TABLET, FILM TABLET, 30 ADET ... EXACCORD 25 FILM COATED TABLET 25 MG ... EXEMESTANE STADA FILM COATED TABLET 25mg …

Gilteritinib

Gilteritinib, also known as ASP2215, is a small molecule part of the FLT3 tyrosine kinase inhibitors that presented a greater selectivity and potency when compared with other agents from this group. It is a pyrazinecarboxamide derivative that showed high selectivity to FLT3 preventing the c-Kit -driven myelosuppression observed in other...
Approved
Investigational
Matched Description: … is a small molecule part of the FLT3 tyrosine kinase inhibitors that presented a greater selectivity and ... [A40044] Gilteritinib was developed by Astellas Pharma and FDA approved on November 28, 2018. ... This drug was approved after being designed as an orphan drug with a fast track and priority review status …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … XOSPATA® FILM-COATED TABLETS 40MG ... XOSPATA 40 MG FİLM KAPLI TABLET, 84 ADET …

Perindopril

Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration. Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to...
Approved
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... be used to treat mild to moderate essential hypertension, mild to moderate congestive heart failure, and ... to reduce the cardiovascular risk of individuals with hypertension or post-myocardial infarction and …
Matched Mixtures name: … Cosyrel 5mg/5mg film-coated tablets ... Cosyrel 5mg/10mg film-coated tablets ... Cosyrel 10mg/5mg film-coated tablets …
Matched Categories: … ACE Inhibitors and Diuretics ... ACE Inhibitors and Calcium Channel Blockers ... perindopril and diuretics ... perindopril and bisoprolol ... perindopril and amlodipine …
Matched Products: … COVERSYL 5MG FILM-COATED TABLETS ... COVERSYL 10MG FILM-COATED TABLETS ... COVERSYL 5 MG FILM TABLET, 30 ADET …

Spironolactone

Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered.[A11837, A178246] It is indicated to treat several conditions, including...
Approved
Matched Description: … [A178192] It promotes sodium and water excretion and potassium retention. ... It binds to mineralocorticoid receptors and functions as aldosterone antagonists. ... [L44602] Off-label uses of spironolactone include hirsutism, female pattern hair loss, and adult acne …
Matched Mixtures name: … Spironolactone and Hydrochlorothiazide ... Spironolactone and Hydrochlorothiazide ... Spironolactone and Hydrochlorothiazide …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SPYLACTON 50 MG FILM KAPLI TABLET, 20 ADET ... SPYLACTON 100 MG FILM KAPLI TABLET, 20 ADET ... SPYLACTON 25 MG FILM TABLET, 20 ADET …

Moexipril

Moexipril is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat. It is used to treat high blood pressure (hypertension). It works by relaxing blood vessels, causing them to widen. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.
Approved
Matched Description: … Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems. …
Matched Mixtures name: … UNIRETIC 15 MG/ 25 MG FILM KAPLI TABLET, 30 ADET ... UNIRETIC 7,5 MG/ 12.5 MG FILM KAPLI TABLET, 30 ADET ... Moexipril Hydrochloride and Hydrochlorothiazide …
Matched Categories: … ACE Inhibitors and Diuretics ... moexipril and diuretics …
Matched Products: … UNIVASC 15 MG FILM TABLET, 20 ADET ... UNIVASC 7,5 MG FILM TABLET, 20 ADET …

Apalutamide

Apalutamide is a potent androgen receptor (AR) antagonist that selectively binds to the ligand-binding domain of AR and blocks AR nuclear translocation or binding to androgen response elements . It has been used in trials studying the treatment of Prostate Cancer, Hepatic Impairment, Prostatic Neoplasms, Castration-Resistant Prostate Cancer, and Prostatic...
Approved
Investigational
Matched Description: … It targets the AR ligand-binding domain and prevents AR nuclear translocation, DNA binding, and transcription ... potent androgen receptor (AR) antagonist that selectively binds to the ligand-binding domain of AR and ... risk for metastases and death [A31846]. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Matched Products: … Erleada 60mg Film-Coated Tablets ... ERLEADA FILM-COATED TABLET 60MG …

Atenolol

Atenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions. Sir James Black, a Scottish pharmacologist, pioneered the use of beta-blockers for the management of angina pectoris in 1958 for which he received the Nobel Prize. Beta-blockers quickly became popular in clinical use and where subsequently investigated for...
Approved
Matched Description: … use in myocardial infarction, arrhythmias, and hypertension during the 1960s. ... [A178429] Beta-blockers quickly became popular in clinical use and where subsequently investigated for ... Atenolol itself was developed early on in this history by Alvogen Malta under the trade name Tenormin and …
Matched Mixtures name: … TENORETIC 100 MG/25 MG FILM TABLET, 28 ADET ... TENORETIC 50 MG/12.5 MG FILM TABLET, 28 ADET ... Atenolol and Chlorthalidone …
Matched Categories: … Beta Blocking Agents and Thiazides ... atenolol and nifedipine ... atenolol and thiazides ... atenolol and other diuretics ... Beta blocking agents and calcium channel blockers …
Matched Products: … ATENOLOL - CT 50 MG FILM ... ATENOLOL - CT 100 MG FILM ... TERNOLOL 50 FILM-COATED TABLET …

Benfotiamine

Benfotiamine has been investigated for the treatment and prevention of Diabetic Nephropathy and Diabetes Mellitus, Type 2.
Approved
Experimental
Matched Description: … Benfotiamine has been investigated for the treatment and prevention of Diabetic Nephropathy and Diabetes …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … NEVRALON B 300 MG FİLM KAPLI TABLET, 30 TABLET ... NEVRALON B 150 MG FİLM KAPLI TABLET, 30 TABLET …

Rufinamide

Rufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy. Clinical trials suggest its efficacy in the treatment of partial seizures.
Approved
Matched Description: … Rufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like …
Matched Products: … Inovelon 200 mg film-coated tablets ... INOVELON FILM-COATED TABLET 200 MG …

Regorafenib

Regorafenib is an orally-administered inhibitor of multiple kinases. It is used for the treatment of metastatic colorectal cancer, advanced gastrointestinal stromal tumours, and hepatocellular carcinoma. FDA approved on September 27, 2012. Approved use of Regorafenib was expanded to treat Hepatocellular Carcinoma in April 2017.
Approved
Matched Description: … used for the treatment of metastatic colorectal cancer, advanced gastrointestinal stromal tumours, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … STIVARGA 40MG FILM-COATED TABLETS ... STIVARGA 40 MG FILM KAPLI TABLET ,84 ADET …

Dronedarone

Dronedarone is a Class III antiarrhythmic drug that works to restore the normal sinus rhythm in patients with paroxysmal or persistent atrial fibrillation. Atrial fibrillation is a common sustained arrhythmia where the treatment primarily focuses on stroke prevention and symptom management. It is managed by rate control, rhythm control, prevention...
Approved
Matched Description: … calcium ion channels and inhibiting β-adrenergic receptors. ... toxicities, such as thyroid and pulmonary toxicities. ... fibrillation is a common sustained arrhythmia where the treatment primarily focuses on stroke prevention and …
Matched Products: … Film-coated Tablet 400mg ... MULTAQ 400 MG FILM-COATED TABLETS …

Albendazole

A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Approved
Vet approved
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Matched Products: … DENZOL 200mg Film Coated Tablets ... ALZOL 200 MG FİLM KAPLI TABLET ... HELMADOL 200 MG FİLM KAPLI TABLET, 6 ADET …

Ceftibuten

Ceftibuten is a third-generation cephalosporin antibiotic that is orally-administered. It is typically used to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.
Approved
Investigational
Matched Description: … acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and …
Matched Mixtures name: … WINCEF PLUS 400/125 MG FILM KAPLI TABLET, 20 ADET ... WINCEF PLUS 400/125 MG FILM KAPLI TABLET, 10 ADET ... WINCEF PLUS 200/62.5 MG FILM KAPLI TABLET, 20 ADET …
Matched Products: … WINCEF 200 MG FILM KAPLI TABLET, 20 ADET ... WINCEF 400 MG FILM KAPLI TABLET, 10 ADET ... WINCEF 400 MG FILM KAPLI TABLET, 20 ADET …
Displaying drugs 926 - 950 of 1075 in total