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Choline magnesium trisalicylate

Choline magnesium trisalicylate is a non-acetylated salicylate used widely as a nonsteroidal anti-inflammatory drug. Trisalicylate significantly reduces methotrexate renal clearance, displacing methotrexate from protein, increasing the fraction unbound by 28% [A19653, A19654].

Approved

Flavin adenine dinucleotide

A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) Flavin adenine dinucleotide is approved for use in Japan under the trade name Adeflavin as an ophthalmic treatment for vitamin B2 deficiency.

Approved

Matched Description: … A condensation product of riboflavin and adenosine diphosphate. ... The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. ... (Lehninger, Principles of Biochemistry, 1982, p972) Flavin adenine dinucleotide is approved for use …

Amylmetacresol

Amylmetacresol is an antiseptic available in Canada over-the-counter in a number of lozenges for the treatment of sore throat and minor mouth infections , . Amylmetacresol is often combined with dichlorobenzyl alcohol and menthol in the commonly used sore throat lozenges, known as Strepsils . The acute sore throat (pharyngitis)...

Approved

Matched Description: … treatment of sore throat and minor mouth infections [L2570], [L2571]. ... symptoms, and are increasingly important in the management of this condition [A32787]. ... Amylmetacresol is an antiseptic available in Canada over-the-counter in a number of lozenges for the …

Human papillomavirus type 58 L1 capsid protein antigen

Human papillomavirus type 58 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 58. The vaccine is prepared from the purified...

Approved

Matched Description: … It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused ... The vaccine is prepared from the purified virus-like particles (VLPs) of the major capsid (L1) protein ... of HPV Type 58 which are produced by separate fermentations in recombinant *Saccharomyces cerevisiae …

Gluconic Acid

Commonly found in salts with sodium and calcium. Gluconic acid or gluconate is used to maintain the cation-anion balance on electrolyte solutions.

Approved

Investigational

Cetrorelix

Cetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). GnRH controls another hormone that is called luteinizing hormone (LH), which is the hormone that starts ovulation during the menstrual cycle. When undergoing hormone treatment sometimes premature ovulation can occur, leading to eggs that are not...

Approved

Investigational

Matched Description: … Cetrorelix does not allow the premature release of these eggs to occur. ... Cetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). …

Norepinephrine

Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is...

Approved

Matched Description: … Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse ... Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic …

Epicriptine

Epicriptine is also known as beta-dihydroergocryptine presents a molecular formula of 9,10 alpha-dihydro-13'-epi-b-ergocryptine. Together with the alpha-dihydroergocryptine, it represents one-third of the ergoloid mesylate mixture. Epicriptine differs from the alpha form on the position of one methyl group. To know more about the mixture please visit DB01049

Approved

Matched Description: … Epicriptine differs from the alpha form on the position of one methyl group. ... Epicriptine is also known as beta-dihydroergocryptine presents a molecular formula of 9,10 alpha-dihydro ... Together with the alpha-dihydroergocryptine, it represents one-third of the ergoloid mesylate mixture …

Interferon alfa-n1

Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least two of which are glycosylated. This differs from recombinant alpha interferons, which are individual non-glycosylated proteins produced from individual alpha interferon genes.

Approved

Investigational

Matched Description: … two of which are glycosylated. ... Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least …

Triflupromazine

A phenothiazine used as an antipsychotic agent and as an antiemetic.

Approved

Vet approved

Metaraminol

An adrenergic agonist that acts predominantly at alpha adrenergic receptors and also stimulates the release of norepinephrine. It has been used primarily as a vasoconstrictor in the treatment of hypotension.

Approved

Investigational

Matched Description: … It has been used primarily as a vasoconstrictor in the treatment of hypotension. ... adrenergic agonist that acts predominantly at alpha adrenergic receptors and also stimulates the release of …

Flunitrazepam

Flunitrazepam is a benzodiazepine with pharmacologic actions similar to those of diazepam that can cause anterograde amnesia. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.

Approved

Illicit

Matched Description: … The United States Government has banned the importation of this drug. ... Flunitrazepam is a benzodiazepine with pharmacologic actions similar to those of diazepam that can cause …

Methsuximide

Mesuximide (or methsuximide) is an anticonvulsant medication. It is sold by Pfizer under the name Petinutin.

Approved

Reviparin

Reviparin is a low molecular weight heparin which seems to have a better safety profile than unfractionated heparin. It is prepared from porcine intestinal mucosa by nitrous acid depolymerization. Reviparin has a molecular weight of 3.9 kDa. It was developed by Abbott laboratories and in 2009, reviparin presented an orphan...

Approved

Investigational

Matched Description: … Reviparin has a molecular weight of 3.9 kDa. …

Carmustine

A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985)....

Approved

Investigational

Matched Description: … It is used in the treatment of brain tumors and various other malignant neoplasms. …

Chymotrypsin

Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins and polypeptides. It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. Like most proteolytic enzymes, chymotrypsin is activated from its inactive zymogen precursor, chymotrypsinogen, in presence...

Approved

Vet approved

Matched Description: … Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins ... enzymes, chymotrypsin is activated from its inactive zymogen precursor, chymotrypsinogen, in presence of ... Chymotrypsin is the most abundant pancreatic proteases that represent up to 10-20% of the total protein …

Influenza A virus A/Switzerland/9715293/2013 NIB-88 (H3N2) antigen (UV, formaldehyde inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...

Approved