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Displaying drugs 951 - 975 of 1348 in total

Pembrolizumab

Pembrolizumab is a highly selective IgG4-kappa humanized monoclonal antibody against PD-1 receptors. It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotype containing a stabilizing S228P Fc mutation. It contains 32 cysteine residues and the complete folded molecule includes...
Approved
Matched Description: … [F136] It was developed by Merck & Co and first approved for the treatment of metastatic malignant melanoma ... as interchain bonds and 23 interchain bonds. ... [A18829] It contains 32 cysteine residues and the complete folded molecule includes 4 disulfide linkages …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … KEYTRUDA SOLUTION FOR INFUSION 25MG/ML ... Keytruda 100mg Solution for Infusion …

Ixekizumab

Ixekizumab is a humanized immunoglobulin G subclass 4 (IgG4) monoclonal antibody (mAb) against interleukin-17A (IL-17A) and prevents it from interacting with the IL-17A receptor. As IL-17A is a pro-inflammatory cytokine involved in inflammation and immune responses, blocking its effect is beneficial for use in inflammatory conditions. In particular, IL-17A has...
Approved
Investigational
Matched Description: … heavy chain polypeptides of 445 amino acids each, and has a molecular weight of 146,158 Daltons for ... for systemic therapy or phototherapy. ... using standard technology for bioprocessing. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Taltz 80mg solution for injection in pre-filled pen ... TALTZ SOLUTION FOR INJECTION IN PRE-FILLED PEN 80 mg/ml ... Taltz 80mg solution for injection in pre-filled syringe …

5-(6-Amino-9h-Purin-9-Yl)-4-Hydroxytetrahydrofuran-3-Yl Dihydrogen Phosphate

Experimental
Matched Name: … 5-(6-Amino-9h-Purin-9-Yl)-4-Hydroxytetrahydrofuran-3-Yl Dihydrogen Phosphate …

Glycyl-L-a-Aminopimelyl-E-(D-2-Aminoethyl)Phosphonate

Experimental
Matched Name: … Glycyl-L-a-Aminopimelyl-E-(D-2-Aminoethyl)Phosphonate …

Oxidronic acid

Approved
Matched Products: … TECHNESCAN HDP FOR INJECTION 3 mg/vial ... TECHNESCAN HDP POWDER FOR INJECTION 3.15 mg/vial …

Ofatumumab

Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic mouse and hybridoma technology. Ofatumumab works by recognizing antigens that are expressed on the tumour cells in certain cancers; however, the antigen is...
Approved
Matched Description: … [A6921] Ofatumumab is available for intravenous administration and is marketed as Arzerra. ... Authorization Application (MAA), respectively, for ofatumumab for the treatment of RMS in adults. ... In February 2020, FDA and EMA approved Supplemental Biologics License Application (sBLA) and Marketing …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … KESIMPTA SOLUTION FOR INJECTION IN PRE-FILLED PEN 20MG/0.4ML ... Bonspri 20mg/0.4mL Solution for Injection in Pre-filled syringe ... KESIMPTA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 20MG/0.4ML …

Ferric carboxymaltose

Ferric carboxymaltose is an iron replacement product and, chemically, an iron-carbohydrate complex. It was FDA approved on July 25, 2013.
Approved
Matched Description: … Ferric carboxymaltose is an iron replacement product and, chemically, an iron-carbohydrate complex. …
Matched Products: … Ferinject Solution for Injection 50mg/ml ... Ferinject® 50 mg iron/mL solution for injection/infusion …

Streptomycin

Streptomycin, an antibiotic derived from Streptomyces griseus, was the first aminoglycoside to be discovered and used in practice in the 1940s.[A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in Medicine for their discovery of streptomycin and its antibacterial activity.[A233325,A232294] Although streptomycin was the first antibiotic...
Approved
Vet approved
Matched Synonyms: … diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranoside …
Matched Iupac: … [(2R,3R,4R,5S)-3-{[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy}-4-formyl …
Matched Description: … Medicine for their discovery of streptomycin and its antibacterial activity. ... [A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in ... Streptomycin, an antibiotic derived from _Streptomyces griseus_, was the first aminoglycoside to be discovered and …
Matched Categories: … Alimentary Tract and Metabolism ... streptomycin and isoniazid ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use ... Drugs for Treatment of Tuberculosis …
Matched Products: … Streptomycin for Injection USP ... STREPTOMYCIN SULFATE FOR INJECTION 1 g/vial …

Palivizumab

Humanized monoclonal antibody (IgG1k) produced by recombinant DNA technology, directed to an epitope in the A antigenic site of the F protein of respiratory syncytial virus (RSV). Synagis is a composite of human (95%) and murine (5%) antibody sequences. The human heavy chain sequence was derived from the constant domains...
Approved
Investigational
Matched Description: … regions of the VH genes Cor (1) and Cess (2). ... Synagis is a composite of human (95%) and murine (5%) antibody sequences. ... 1-2% carbohydrate by weight and has a molecular weight of 147.7 kDa +/- 1 kDa (MALDI-TOF) …
Matched Categories: … Antiinfectives for Systemic Use ... Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Matched Products: … Synagis 100mg/ml solution for Injection ... SYNAGIS SOLUTION FOR INJECTION 100MG/ML ... SYNAGIS STERILE POWDER FOR INJECTION 100 mg/vial …

Montmorillonite

Experimental
Investigational
Matched Mixtures name: … SEED Teatree and Lime Vegan No-sebum Cool Anti HairlossShampoo …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … DIMECTAL Powder for Oral Suspension 3g ... Smecta Strawberry Flavour Powder for Oral Suspension 3g ... Smecta Orange-Vanilla Flavour Powder for Oral Suspension 3g …

Basiliximab

A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also known as CD25 antigen) on the surface of activated T-lymphocytes. It is a 144 kDa glycoprotein obtained from fermentation of an established mouse myeloma cell...
Approved
Investigational
Matched Description: … light chain constant region genes and mouse heavy and light chain variable region genes encoding the ... ) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and ... established mouse myeloma cell line genetically engineered to express plasmids containing the human heavy and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … SIMULECT FOR INJECTION 20 mg/vial ... SIMULECT LYOPHILISATE FOR INJECTION 20MG PER VIAL …

Etanercept

Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.[L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1....
Approved
Investigational
Matched Description: … [L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region ... variety of inflammatory conditions including rheumatoid arthritis (RA), ankylosing spondylitis (AS), and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Biologics for Rheumatoid Arthritis Treatment …
Matched Products: … ENBREL FOR INJECTION 25 mg/vial ... Enbrel Solution for Injection in a Pre-filled Pen 50mg ... Enbrel Solution for Injection in a Pre-filled Syringe 50mg …

Phenothrin

Experimental
Matched Categories: … Scabicides, Insecticides and Repellents ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … BI-SOL FORT SAMPUAN, 60 ML …

Ropivacaine

Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.
Approved
Matched Description: … It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the …
Matched Products: … ROPIVACAINE-AFT SOLUTION FOR INJECTION 1% W/V ... ROPIVACAINE-AFT SOLUTION FOR INFUSION 0.2% W/V ... ROPIVACAINE-AFT SOLUTION FOR INJECTION 0.2% W/V …

Bicisate

Bicisate, also known as ethyl cysteinate dimer (ECD), is a N,N'-1,2-ethylene-di-yl-bis-L-cysteinate diethyl ester. It is used in conjunction with technetium Tc99m as a tracer to measure cerebral blood flow with single-photon emission computed tomography (SPECT). The complex of bicisate and technetium Tc99m as a kit was developed by Lantheus Medcl...
Approved
Investigational
Matched Description: … [A32374] The complex of bicisate and technetium Tc99m as a kit was developed by Lantheus Medcl and FDA-approved …
Matched Products: … NEUROLITE KIT FOR THE PREPARATION OF Tc99m BICISATE FOR INJECTION …

Bucladesine

Experimental
Matched Synonyms: … dibutyryl adenosine 3',5'-cyclic phosphate …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Rasburicase

Rasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified Saccharomyces cerevisiae strain. The cDNA coding for rasburicase was cloned from a strain of Aspergillus flavus.
Approved
Investigational
Matched Description: … The cDNA coding for rasburicase was cloned from a strain of _Aspergillus flavus_. …
Matched Categories: … Enzymes and Coenzymes ... Detoxifying Agents for Antineoplastic Treatment …
Matched Products: … FASTURTEC POWDER FOR SOLUTION FOR INFUSION 1.5 mg/vial …

Gadoxetic acid

Gadoxetic acid (gadoxetate) is a paramagnetic gadolinium-containing ionic linear contrast agent in which its salt form, gadoxetate disodium, is used for intravenous injection. Ethoxybenzyl diethylenetriaminepentaacetic acid is the moiety that chelates with a gadolinium ion and forms a stable complex with it to make up the drug. Gadoxetate is a...
Approved
Matched Description: … hepatobiliary phase and thus has different pharmacokinetic and pharmacodynamic properties compared to ... forms a stable complex with it to make up the drug. ... , gadoxetate disodium, is used for intravenous injection. …
Matched Products: … Primovist 0.25 mmol/ml Solution for injection ... PRIMOVIST 0.25 MMOL/ML, SOLUTION FOR INJECTION …

Romosozumab

Romosozumab is a humanized monoclonal antibody indicated for the treatment of osteoperosis in postmenopausal women at high risk of fracture and patients who have failed in other treatments or are intolerant to other osteoperosis therapies . Romosozumab prevents bone resorption and induces the formation of bone though it is associated...
Approved
Investigational
Matched Description: … In a comparison study of post menopausal women with osteoporosis and a past fracture, romosozumab for ... 12 months followed by alendronic acid for 12 months was superior to alendronic acid alone for 24 months ... increased risk of cardiac death, heart attack, and stroke in one study[L5921,L5924]. …
Matched Categories: … Drugs for Treatment of Bone Diseases ... Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105 MG/1.17 ML ... EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105MG/1.17ML …

Micafungin

Micafungin is an antifungal drug. It belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall.
Approved
Investigational
Matched Description: … It belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antimycotics for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Mycamine 50 mg/vial powder for solution for infusion ... MYCAMINE POWDER FOR SOLUTION FOR INFUSION 50MG/VIAL ... Micafungin for Injection …

Teriparatide

Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Europe in April 2003, teriparatide makes the first approved drug in...
Approved
Investigational
Matched Description: … Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. ... [A251395] First approved in the United States in November 2002 and in Europe in April 2003,[A251400] ... [A251395] Teriparatide is used in the treatment of osteoporosis in men and women.[L42590, L42595] …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Parathyroid Hormones and Analogues ... Calcium-Regulating Hormones and Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … FORTEO 250 UG SOLUTION FOR INJECTION ... MEGAPTH-G Teriparatide 20 micrograms / 80 microliters solution for injection ... SONDELBAY (Teriparatide) 20 micrograms/ 80 microliters solution for injection in pre-filled pen …

Ocrelizumab

Ocrelizumab is a CD20-directed cytolytic antibody indicated for the treatment of patients with primary progressive or relapsing forms of multiple sclerosis (MS). It is a second-generation recombinant humanized monoclonal IgG1 antibody that selectively targets B-cells that express the CD20 antigen. Compared to non-humanized CD20 antibodies such as rituximab, ocrelizumab is...
Approved
Investigational
Matched Description: … PPMS in both the US and Canada. ... relapse rates and reduced worsening of disability compared to [interferon beta-1a]. ... with MS, and leads to the gradual worsening of neurologic disability from symptom onset, often without …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … OCREVUS 300mg/10mL Concentrate for Solution for Infusion …

Lavender oil

Approved
Experimental
Matched Synonyms: … Lavandula vulgaris flowering top oil …

Acacia

Acacia allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Plants and plant parts, gum, acacia or arabic acacia senegal …

Piperacillin

Semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. It is also used in combination with other antibiotics.
Approved
Matched Description: … Semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas …
Matched Mixtures name: … Piperacillin and Tazobactam for Injection ... Piperacillin and Tazobactam for Injection ... Piperacillin and Tazobactam for Injection …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … PIPERACILLIN/TAZOBACTAM KABI POWDER FOR SOLUTION FOR INFUSION 4G/0.5G ... Piperacillin for Injection …
Displaying drugs 951 - 975 of 1348 in total