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Displaying drugs 1076 - 1100 of 1231 in total
A narcotic analgesic and antitussive. It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function. It is not marketed in the US but is approved for use in various countries around the world. In the US it is a schedule II drug (single-entity) and...
Experimental
Illicit
Matched Synonyms: … Dionine
Matched Description: … A narcotic analgesic and antitussive. ... It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function ... In the US it is a schedule II drug (single-entity) and schedule III drug (in combination products). …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives …
Choline magnesium trisalicylate is a non-acetylated salicylate used widely as a nonsteroidal anti-inflammatory drug. Trisalicylate significantly reduces methotrexate renal clearance, displacing methotrexate from protein, increasing the fraction unbound by 28% [A19653, A19654].
Approved
Matched Name: … Choline magnesium trisalicylate …
Matched Iupac: … magnesium(2+) (2-hydroxyethyl)trimethylazanium tris(2-hydroxybenzoate) …
Matched Description: … Choline magnesium trisalicylate is a non-acetylated salicylate used widely as a nonsteroidal anti-inflammatory …
Attapulgite is a magnesium aluminium phyllosilicate which occurs in a type of clay soil common to the Southeastern United States. When used in medicine, it physically binds to acids and toxic substances in the stomach and digestive tract. For that reason, it has often been used in antidiarrheal medications. Until...
Approved
Vet approved
Matched Synonyms: … Aluminium magnesium silicate (attapulgite) …
Matched Iupac: … tetrasilicon(4+) ion aluminium(3+) ion magnesium(2+) ion tetrahydrate hydroxide decaoxidandiide …
Matched Description: … When used in medicine, it physically binds to acids and toxic substances in the stomach and digestive ... Attapulgite is a magnesium aluminium phyllosilicate which occurs in a type of clay soil common to the …
Matched Categories: … Alimentary Tract and Metabolism …
Experimental
Matched Name: … (RP,SP)-O-(2R)-(1-PHENOXYBUT-2-YL)-METHYLPHOSPHONIC ACID CHLORIDE
Investigational
Matched Synonyms: … Ammonium molybdenum sulfide ((nh4)2mos4) …
Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat...
Approved
Matched Synonyms: … 3-benzylthiomethyl-6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide ... 3-((benzylthio)methyl)-6-chloro-7-sulfamoyl-2H-benzo-1,2,4-thiadiazine 1,1-dioxide ... 3-benzylthiomethyl-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
Matched Description: … Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in ... Thiazides also cause loss of potassium and an increase in serum uric acid. ... Benzthiazide is used to treat hypertension and edema. …
Matched Categories: … Sodium Chloride Symporter Inhibitors ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Grazoprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Matched Synonyms: … Grazoprevir anhydrous
Matched Description: … to achieve a SVR between 94% and 97% for genotype 1 and 97% and 100% for genotype 4 after 12 weeks of ... into mature proteins like NS3, NS4A, NS4B, NS5A and NS5B [FDA Label]. ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and
Matched Categories: … elbasvir and grazoprevir …
Navarixin has been investigated for the treatment of Asthma.
Investigational
Matched Synonyms: … Navarixin anhydrous
Peramivir is an antiviral agent developed by Biocryst Pharmaceuticals to treat influenza A/B. The development of peramivir has been supported by the US Department of Health and Human Services as part of the government's effort to prepare for a flu pandemic. Being an influenza virus neuraminidase inhibitor, peramivir works by...
Approved
Investigational
Matched Synonyms: … Peramivir anhydrous
Matched Description: … The development of peramivir has been supported by the US Department of Health and Human Services as ... the poor oral bioavailability, the oral formulation of the drug was previously abandoned by Johnson and ... in September 2017 for the treatment of acute uncomplicated influenza to pediatric patients 2 years and
Investigational
Matched Synonyms: … PXL770 free acid anhydrous ... PXL 770 free acid anhydrous
Matched Name: … PXL-770 free acid anhydrous
Investigational
Matched Name: … DDP-225 free base anhydrous
Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels.[A255647,L44612] It is chemically related to thiazide diuretics but does not inhibit carbonic anhydrase and does not have chloriuretic or natriuretic activity. Diazoxide is commonly used in the treatment of hyperinsulinaemic hypoglycemia due to its ability to inhibit insulin release....
Approved
Matched Synonyms: … 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
Matched Description: … Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels ... [A255647] Diazoxide also exhibits hypotensive activity and reduces arteriolar smooth muscle and vascular ... and electrolyte disturbances. …
Matched Categories: … Potassium Channel Opener …
Argatroban is a direct, selective thrombin inhibitor. The American College of Cardiologists (ACC) recommend using bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and are undergoing percutaneous coronary intervention. Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients...
Approved
Investigational
Matched Synonyms: … Argatroban anhydrous
Matched Description: … bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and ... Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients with HIT and ... Parental anticoagulants must be stopped and a baseline activated partial thromboplastin time must be …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial perfusion imagining. Manufactured by Astellas and FDA approved April 10, 2008.
Approved
Investigational
Matched Synonyms: … Regadenoson anhydrous
Matched Description: … Manufactured by Astellas and FDA approved April 10, 2008. ... Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial …
Enalaprilat is the active metabolite of the orally available pro-drug, enalapril. Used in the treatment of hypertension, enalapril is an ACE inhibitor that prevents Angiotensin Converting Enzyme (ACE) from transforming angiotensin I into angiotensin II. As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule of...
Approved
Matched Synonyms: … Enalaprilat anhydrous
Matched Description: … As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule ... of the kidney, down-regulation of this protein results in reduced blood pressure and blood fluid volume ... to overcome the limitations of the first ACE inhibitor, captopril, which had numerous side effects and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tofogliflozin has been used in trials studying the treatment and prevention of Diabetes Mellitus Type 2.
Investigational
Matched Synonyms: … Tofogliflozin anhydrous
Matched Description: … Tofogliflozin has been used in trials studying the treatment and prevention of Diabetes Mellitus Type …
Matched Categories: … Sodium-Glucose Transporter 2 Inhibitors …
Relebactam is a diazabicyclooctane beta-lactamase inhibitor, similar in structure to avibactam.[A181195,A181207] It includes a piperidine ring which reduces export from bacterial cells by producing a positive charge. It is currently available in a combination product which includes imipenem and cilastatin to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated...
Approved
Investigational
Matched Synonyms: … Relebactam anhydrous
Matched Description: … [A181207] It is currently available in a combination product which includes [imipenem] and [cilastatin ... ] to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated intra-abdominal ... [label] It is considered to be a last-line treatment option and gained FDA approval as part of the combination …
Matched Salts name: … Relebactam sodium
Matched Categories: … imipenem, cilastatin and relebactam …
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
Approved
Matched Synonyms: … 6-trifluoromethyl-3-benzyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide ... ±-3-benzyl-3,4-dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. ... It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders …
Matched Mixtures name: … Nadolol and Bendroflumethiazide ... Nadolol and Bendroflumethiazide ... Nadolol and Bendroflumethiazide …
Matched Categories: … Sodium Chloride Symporter Inhibitors ... bendroflumethiazide and potassium ... Low-Ceiling Diuretics and Potassium-Sparing Agents ... bendroflumethiazide and potassium-sparing agents ... Genito Urinary System and Sex Hormones …
Pabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With Mucopolysaccharidosis II).
Investigational
Matched Synonyms: … anti-(human transferrin receptor 1, tfr1) humanized monoclonal antibody, fused with human iduronate-2-sulfatase ... ) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC 2-AMINO ACID LINKER) FUSION PROTEIN WITH HUMAN IDURONATE-2-SULFATASE
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
A dextrodisaccharide from malt and starch. It is used as a sweetening agent and fermentable intermediate in brewing (Grant & Hackh's Chemical Dictionary, 5th ed).
Experimental
Investigational
Matched Synonyms: … Maltose anhydrous
Matched Description: … A dextrodisaccharide from malt and starch. ... It is used as a sweetening agent and fermentable intermediate in brewing (Grant & Hackh's Chemical …
Matched Categories: … Diet, Food, and Nutrition …
Gadodiamide is a linear, non-ionic gadolinium-based contrast agent (GBCA) that is used in magnetic resonance imaging (MRI) procedures to assist in the visualization of blood vessels.[A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than nonionic iodinated contrast agents. Approved by the FDA...
Approved
Investigational
Matched Synonyms: … Gadodiamide anhydrous
Matched Description: … [A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than ... macrocyclic or ionic GBCA, gadodiamide can potentially lead to more gadolinium retention in the brain and
Experimental
Matched Synonyms: … Fluourine-18 Fluoromethylcholine …
Matched Salts name: … Fluorocholine chloride F-18 …
Matched Categories: … Fluorine Radioisotopes …
Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Vet approved
Matched Description: … Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and ... through aerobic or anaerobic respiration and fermentation. ... It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis …
Matched Mixtures name: … Magnesium Sulfate In 5% Dextrose Inj(20mg/ml) ... Potassium Chloride in Dextrose and Sodium Chloride ... Potassium Chloride in Dextrose and Sodium Chloride
Matched Products: … %5 DEKSTROZ %0.9 SODYUM KLORÜR ÇÖZELTİSİ 500 ML (ŞİŞE) SETSİZ ... %5 DEKSTROZ %0.9 SODYUM KLORÜR ÇÖZELTİSİ 1000 ML (ŞİŞE) SETSİZ …
Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency. It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia.
Approved
Matched Synonyms: … Hydroxocobalamin anhydrous ... Hydroxocobalaminum anhydrous
Matched Iupac: … undecamethyl-15,20-dioxo-11,14,16-trioxa-2lambda5,9,19,26,43lambda5,44lambda5,45lambda5-heptaaza-15lambda5-phospha
Matched Description: … Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B ... It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia. …
Matched Categories: … Blood and Blood Forming Organs ... Vitamin B12 and Folic Acid …
Approved
Matched Synonyms: … Anhydrous lithium citrate ... Lithium citrate (anhydrous) …
Displaying drugs 1076 - 1100 of 1231 in total