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Displaying drugs 1076 - 1100 of 1564 in total
Vaccine against Lyme disease that contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, as expressed by Escherichia coli. Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus. It is conjugated with alum (aluminum hydroxide) as...
Approved
Withdrawn
Matched Synonyms: … Lipoprotein outer surface a borrelia burgdorferi antigen …
Matched Description: … It is conjugated with alum (aluminum hydroxide) as an adjuvant. ... sensu stricto ZS7, as expressed by Escherichia coli. ... Vaccine against Lyme disease that contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi …
Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum. It is beneficial in the breakdown of collagen plaques for the treatment of Dupuytren's contracture and Peyronie's disease. The topical formulation is used for the debridement of necrotic tissue due to burns or chronic ulcers. On July 6,...
Approved
Investigational
Matched Synonyms: … Clostridiopeptidase A
Matched Description: … [L14872] Also known as Qwo, this injection is the first approved injectable treatment for cellulite and ... It is beneficial in the breakdown of collagen plaques for the treatment of Dupuytren's contracture and ... Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum. …
Matched Categories: … Skin and Mucous Membrane Agents ... Enzymes and Coenzymes ... Preparations for Treatment of Wounds and Ulcers …
A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. It has been shown in some cases to be more potent than diazepam or nitrazepam.
Approved
Illicit
Matched Synonyms: … 8-chloro-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine …
Matched Description: … A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. ... It has been shown in some cases to be more potent than diazepam or nitrazepam. …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives ... Drugs that are Mainly Renally Excreted …
Mimopezil is an acetylcholinesterase (AChE) inhibitor that has demonstrated potential use in the treatment of Alzheimer's disease. Mimopezil is a pro-drug that is rapidly absorbed and converted into huperzine A.
Investigational
Matched Synonyms: … N-(2-Hydroxy-3-methoxy-5-chlorobenzylidene)huperzine A
Matched Description: … Mimopezil is a pro-drug that is rapidly absorbed and converted into huperzine A. ... Mimopezil is an acetylcholinesterase (AChE) inhibitor that has demonstrated potential use in the treatment …
Esmirtazapine, known by the standardized identifier SCH 900265, was under development by Organon to treat insomnia and vasomotor symptoms associated with menopause. Esmirtazapine is the (S)-(+)-enantiomer of mirtazapine and possesses similar overall pharmacology. This includes inverse agonist activity of H1 and 5-HT2 receptors and antagonism of α2-adrenergic receptors. Merck has...
Investigational
Matched Synonyms: … (S)-1,2,3,4,10,14b-hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)(2)benzazepine …
Matched Description: … This includes inverse agonist activity of H1 and 5-HT2 receptors and antagonism of α2-adrenergic receptors ... known by the standardized identifier SCH 900265, was under development by Organon to treat insomnia and ... Esmirtazapine is the (S)-(+)-enantiomer of mirtazapine and possesses similar overall pharmacology. …
Investigational
Matched Synonyms: … A cd33/cd3 bispecific t-cell engager antibody for acute myeloid leukemia therapy …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Crotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use only. It is a colorless to slightly yellowish oil, having a faint amine-like odor. It is miscible with alcohol and with methanol.
Approved
Matched Description: … Crotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use only ... It is miscible with alcohol and with methanol. ... It is a colorless to slightly yellowish oil, having a faint amine-like odor. …
Matched Categories: … Scabicides and Pediculicides ... Toxic Actions ... Compounds used in a research, industrial, or household setting …
Matched Products: … A-Bite Cream ... CROTAMITON LOCION AL 10 % …
Investigational
Matched Synonyms: … Proliferation arrested myelomonocytic leukemic cell line-derived cells with a mature dendritic cell phenotype …
Gemcitabine is a nucleoside analog and a chemotherapeutic agent. It was originally investigated for its antiviral effects, but it is now used as an anticancer therapy for various cancers. Gemcitabine is a cytidine analog with two fluorine atoms replacing the hydroxyl on the ribose. As a prodrug, gemcitabine is transformed...
Approved
Matched Description: … [L32950] It is also being investigated in other cancer and tumour types. ... Gemcitabine is a nucleoside analog and a chemotherapeutic agent. ... [A233140] Gemcitabine is marketed as Gemzar and it is available as intravenous injection. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides ... Toxic Actions ... Drugs that are Mainly Renally Excreted ... P-glycoprotein substrates with a Narrow Therapeutic Index …
Matched Products: … Aj-gemcitabine ... Act Gemcitabine ... PAMIGEN® 200MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIONINYECTABLE …
Nortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.
Approved
Matched Synonyms: … 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamine ... 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine …
Matched Description: … [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain ... and other conditions. ... Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index …
Matched Products: … Ava-nortriptyline ... Apo-nortriptyline ... APO-NORTRIPTYLINE CAPSULE 25 mg …
Agalsidase alfa is a recombinant human α-galactosidase A similar to agalsidase beta. While patients generally do not experience a clinically significant difference in outcomes between the two drugs, some patients may experience greater benefit with agalsidase beta.[A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa,...
Approved
Matched Synonyms: … alpha-galactosidase A ... Recombinant alpha-galactosidase A
Matched Description: … Agalsidase alfa is a recombinant human α-galactosidase A similar to [agalsidase beta]. ... While patients generally do not experience a clinically significant difference in outcomes between the ... A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after a
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Glatiramer acetate is a mix of synthetic polypeptides that includes L-glutamic acid, L-alanine, L-tyrosine, and L-lysine at an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. Since glatiramer acetate is a heterogeneous drug, there is limited information about its physicochemical properties. Originally, glatiramer acetate was designed as a...
Approved
Investigational
Matched Synonyms: … (T,G)-A-L …
Matched Description: … , and L-lysine at an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. ... [A248880] It was approved by the FDA in 1996, and a generic version became available in 2017. ... [A248870] Along with [human interferon beta], [teriflunomide], and [dimethyl fumarate], glatiramer acetate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
RGX-111 is an adeno-associated virus vector AAV9 designed to deliver the α-L-iduronidase (IDUA) gene. Developed by REGENXBIO Inc., it was investigated for the treatment of mucopolysaccharidosis Type I (MPS I).
Investigational
Matched Synonyms: … Adeno-associated virus vector serotype 9 expressing human a-L-iduronidase …
Matched Description: … Developed by REGENXBIO Inc., it was investigated for the treatment of mucopolysaccharidosis Type I (MPS ... RGX-111 is an adeno-associated virus vector AAV9 designed to deliver the α-L-iduronidase (IDUA) gene. …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Michigan/45/2015 (H1N1) recombinant hemagglutinin antigen …
Matched Description: … There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Uruguay/716/2007(H3N2) antigen (propiolactone inactivated) …
Matched Description: … There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Kansas/14/2017 (H3N2) recombinant hemagglutinin antigen …
Matched Description: … There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Wisconsin/588/2019 (H1N1) recombinant hemagglutinin antigen …
Matched Description: … There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Approved
Matched Name: … Influenza A virus A/Tasmania/503/2020 (H3N2) recombinant hemagglutinin antigen …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Switzerland/9715293/2013 (H3N2) recombinant hemagglutinin antigen …
Matched Description: … There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Brisbane/02/2018 (H1N1) recombinant hemagglutinin antigen …
Matched Description: … There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Minnesota/41/2019 (H3N2) recombinant hemagglutinin antigen …
Matched Description: … There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the...
Nutraceutical
Matched Description: … The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream ... Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, ... Calcium gluconate and calcium lactate are absorbed well by pregnant women. …
Matched Mixtures name: … Sub small molecule disinfectant ... Champs Emulsion Cod Liver Oil Orange ... Calci A and D Tab …
Matched Categories: … Antacids and Adsorbents ... Alimentary Tract and Metabolism ... multivitamins and calcium ... Calcium-Regulating Hormones and Agents ... ascorbic acid (vit C) and calcium …
Matched Products: … Ag-X ... P D All ... P D All M …
Rabies virus inactivated antigen, A is an inactivated virus vacine for the intramuscular injection. It is an active immunization against rabies that can be administered pre- or post-exposure to the rabies virus.
Approved
Investigational
Matched Name: … Rabies virus inactivated antigen, A
Matched Description: … Rabies virus inactivated antigen, A is an inactivated virus vacine for the intramuscular injection. ... It is an active immunization against rabies that can be administered pre- or post-exposure to the rabies …
Matched Categories: … Immune Sera and Immunoglobulins …
Aluminum chloride is a chemical compound with the chemical formula AlCl3. When contaminated with iron chloride, it often displays a yellow color compared to the white pure compound. It is used in various chemical applications as a Lewis base, with anhydrous aluminium trichloride being the most commonly used Lewis acid....
Approved
Investigational
Matched Description: … It may also be found in over-the-counter as an antiperspirant or prescription products as an antihemorrhagic ... It is used in various chemical applications as a Lewis base, with anhydrous aluminium trichloride being ... In antiperspirant products, FDA approves the use of aluminum chloride as an active ingredient up to 15% …
Matched Categories: … Astringents and Deodorants ... Compounds used in a research, industrial, or household setting …
Matched Products: … Frenna AC ... Hemox A ... Xerac AC
Beta-carotene, with the molecular formula C40H56, belongs to the group of carotenoids consisting of isoprene units. The presence of long chains of conjugated double bonds donates beta-carotene with specific colors. It is the most abundant form of carotenoid and it is a precursor of the vitamin A. Beta-carotene is composed...
Approved
Nutraceutical
Matched Synonyms: … all-trans-β-carotene …
Matched Description: … It is an antioxidant that can be found in yellow, orange and green leafy vegetables and fruits. ... [T162] It is the most abundant form of carotenoid and it is a precursor of the vitamin A. ... [T158] Under the FDA, beta-carotene is considered as a generally recognized as safe substance (GRAS). …
Matched Mixtures name: … Eden With Vitamins A, C, and E ... Bodysmarts With Vitamins A, C and E ... Beta A With Vitamins C and E Plus Selenium …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... Emollients and Protectives ... Vitamin A
Matched Products: … Beta A 10000 Cap ... BETA-CAROTENE 15 MGPROVITAMIN A 25.000 IU …
Displaying drugs 1076 - 1100 of 1564 in total