Displaying drugs 1101 - 1125 of 1847 in total
Gluconic Acid
Commonly found in salts with sodium and calcium. Gluconic acid or gluconate is used to maintain the cation-anion balance on electrolyte solutions.
Approved
Investigational
Matched Synonyms: … D-Gluconic Acid …
Matched Description: … Commonly found in salts with sodium and calcium. …
Matched Mixtures name: … Plasma-Lyte 148 and dextrose ... Normosol-R and Dextrose ... Normosol-R and Dextrose …
Matched Description: … Commonly found in salts with sodium and calcium. …
Matched Mixtures name: … Plasma-Lyte 148 and dextrose ... Normosol-R and Dextrose ... Normosol-R and Dextrose …
Amdoxovir
Investigational
Matched Synonyms: … beta-D-2,6-Diaminopurine-dioxolane …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
1D-myo-inositol 1,4,5-trisphosphate
Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity...
Experimental
Matched Synonyms: … D-myo-Inositol 1,4,5-trisphosphate ... D-myo-Inositol-1,4,5-triphosphate …
LSTA1
Investigational
Matched Synonyms: … L-cysteine, l-cysteinyl-l-arginylglycyl-l-.alpha.-aspartyl-l-lysylglycyl-l-prolyl-l-.alpha. …
Parasorbic acid
Sole constituent of "Vogelbeerol" oil obtained by steam distillation of the acidified juice of the ripe berries of the mountain ash.
Experimental
Matched Synonyms: … Sorbic oil …
Matched Description: … Sole constituent of "Vogelbeerol" oil obtained by steam distillation of the acidified juice of the ripe …
Matched Description: … Sole constituent of "Vogelbeerol" oil obtained by steam distillation of the acidified juice of the ripe …
Ethyl Oxo(Piperidin-1-Yl)Acetate
Experimental
Matched Name: … Ethyl Oxo(Piperidin-1-Yl)Acetate …
Matched Iupac: … ethyl 2-oxo-2-(piperidin-1-yl)acetate …
Matched Iupac: … ethyl 2-oxo-2-(piperidin-1-yl)acetate …
Reltecimod
Reltecimod is under investigation in clinical trial NCT02469857 (Phase III Efficacy and Safety Study of AB103 in the Treatment of Patients With Necrotizing Soft Tissue Infections).
Investigational
Matched Synonyms: … D-alanyl-L-seryl-L-prolyl-L-methionyl-L-leucyl-L-valyl-L-alanyl-L-tyrosyl-L-aspartyl-D-alanine …
Matched Description: … Reltecimod is under investigation in clinical trial NCT02469857 (Phase III Efficacy and Safety Study …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Costimulatory and Inhibitory T-Cell Receptors …
Matched Description: … Reltecimod is under investigation in clinical trial NCT02469857 (Phase III Efficacy and Safety Study …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Costimulatory and Inhibitory T-Cell Receptors …
Thymalfasin
Thymalfasin is a chemically synthesized version of thymosin alpha 1 that is identical to human thymosin alpha 1. Thymosin alpha 1 is an acetylated polypeptide. Thymosin alpha 1 is now approved in 35 developing countries for the treatment of Hepatitis B and C. It is also used to boost the...
Investigational
Matched Synonyms: … Thymosin alpha1 (human) …
Matched Description: … Thymosin alpha 1 is now approved in 35 developing countries for the treatment of Hepatitis B and C. ... alpha 1. ... Thymosin alpha 1 is an acetylated polypeptide. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Thymosin alpha 1 is now approved in 35 developing countries for the treatment of Hepatitis B and C. ... alpha 1. ... Thymosin alpha 1 is an acetylated polypeptide. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Idursulfase
Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. Idursulfase is produced by recombinant DNA technology in a human cell line. Idursulfase is an enzyme that hydrolyzes the 2-sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and heparan sulfate in the lysosomes of various...
Approved
Matched Synonyms: … Alpha-L-iduronate sulfate sulfatase …
Matched Description: … -sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and ... Idursulfase is produced by recombinant DNA technology in a human cell line. …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Description: … -sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and ... Idursulfase is produced by recombinant DNA technology in a human cell line. …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
D-Aspartic Acid
The D-isomer of aspartic acid. [PubChem]
Experimental
Matched Name: … D-Aspartic Acid …
Matched Description: … The D-isomer of aspartic acid. [PubChem] …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … The D-isomer of aspartic acid. [PubChem] …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Acenocoumarol
Acenocoumarol is a coumarin derivative used as an anticoagulant. Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes with coagulation. Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. Patients...
Approved
Investigational
Matched Synonyms: … 3-(alpha-Acetonyl-4-nitrobenzyl)-4-hydroxycoumarin ... 3-(alpha-Acetonyl-p-nitrobenzyl)-4-hydroxycoumarin ... 3-(alpha-(4'-Nitrophenyl)-beta-acetylethyl)-4-hydroxycoumarin …
Matched Description: … This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes ... [A188739] Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. …
Matched Categories: … Blood and Blood Forming Organs ... Warfarin and isomers …
Matched Description: … This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes ... [A188739] Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. …
Matched Categories: … Blood and Blood Forming Organs ... Warfarin and isomers …
Travoprost
Travoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective FP prostanoid receptor agonist. It is used to decrease intraocular pressure in open-angle glaucoma and ocular hypertension. Unlike other prostaglandin analogues, travoprost demonstrates full agonism and high selectivity at the prostanoid receptor, reporting a higher...
Approved
Matched Synonyms: … (1R-(1.ALPHA. ... ISOPROPYL (Z)-7-((1R,2R,3R,5S)-3,5-DIHYDROXY-2-((1E,3R)-3-HYDROXY-4-((.ALPHA.,.ALPHA.,.ALPHA. ... (Z),2.BETA.(1E,3R*),3.ALPHA.,5.ALPHA.))-7-(3,5-DIHYDROXY-2-(3-HYDROXY-4-(3-(TRIFLUOROMETHYL)PHENOXY)- …
Matched Description: … Travoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective ... It is used to decrease intraocular pressure in open-angle glaucoma and ocular hypertension. ... [L49434] Unlike other prostaglandin analogues, travoprost demonstrates full agonism and high selectivity …
Matched Mixtures name: … DUO TRAV EYE DROPS ... TRAVAPRESS DUO 40 MCG+5 MG/ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … TRAVOPROST DOC GENERICI …
Matched Description: … Travoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective ... It is used to decrease intraocular pressure in open-angle glaucoma and ocular hypertension. ... [L49434] Unlike other prostaglandin analogues, travoprost demonstrates full agonism and high selectivity …
Matched Mixtures name: … DUO TRAV EYE DROPS ... TRAVAPRESS DUO 40 MCG+5 MG/ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … TRAVOPROST DOC GENERICI …
9-Hydroxy-8-Methoxy-6-Nitro-Phenanthrol[3,4-D][1,3]Dioxole-5-Carboxylic Acid
Experimental
Matched Name: … 9-Hydroxy-8-Methoxy-6-Nitro-Phenanthrol[3,4-D][1,3]Dioxole-5-Carboxylic Acid …
Matched Iupac: … 9-hydroxy-8-methoxy-6-nitro-2H-phenanthro[3,4-d][1,3]dioxole-5-carboxylic acid …
Matched Iupac: … 9-hydroxy-8-methoxy-6-nitro-2H-phenanthro[3,4-d][1,3]dioxole-5-carboxylic acid …
5-(3-HYDROXYPHENYL)ISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDE
Experimental
Matched Name: … 5-(3-HYDROXYPHENYL)ISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDE …
Amitriptyline
Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.
Approved
Matched Synonyms: … 10,11-dihydro-5-(γ-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene ... 10,11-dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-Δ5,γ-propylamine ... 5-(γ-dimethylaminopropylidene)-5H-dibenzo[a,d][1,4]cycloheptadiene …
Matched Mixtures name: … Limbitrol DS ... Etrafon D Tab ... CUAIT - D COMPRIMIDOS. …
Matched Categories: … amitriptyline and psycholeptics ... Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Dom-amitriptyline ... AMITRIPTILINA DOC …
Matched Mixtures name: … Limbitrol DS ... Etrafon D Tab ... CUAIT - D COMPRIMIDOS. …
Matched Categories: … amitriptyline and psycholeptics ... Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Dom-amitriptyline ... AMITRIPTILINA DOC …
Velmanase alfa
Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy to treat alpha-mannosidosis. Alpha-mannosidosis is a rare autosomal recessive lysosomal storage disorder. Patients with alpha-mannosidosis have a genetic mutation that causes a deficiency in the lysosomal enzyme alpha-mannosidase, which is an enzyme responsible for breaking down complex...
Approved
Investigational
Matched Synonyms: … Recombinant Human Alpha Mannosidase …
Matched Description: … sugars in the body leads to an array of clinical manifestations leading to progressive neuromuscular and ... deterioration, such as skeletal abnormalities, motor function impairment, intellectual disability, and ... to treat alpha-mannosidosis. …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Recombinant Human Lysosomal alpha-Mannosidase …
Matched Description: … sugars in the body leads to an array of clinical manifestations leading to progressive neuromuscular and ... deterioration, such as skeletal abnormalities, motor function impairment, intellectual disability, and ... to treat alpha-mannosidosis. …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Recombinant Human Lysosomal alpha-Mannosidase …
Polydatin
Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline structure. While it is isolated from the bark of Picea sitchensis or Polygonum cuspidatum, polydatin may be detected in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products and many daily diets...
Approved
Matched Synonyms: … resveratrol-3-O-b-mono-D-glucoside ... trans-resveratrol 3-β-D-glucoside ... trans-resveratrol 3-O-β-D-glucoside …
Matched Description: … Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline ... in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products and ... Polydatin possesses anti-inflammatory, immunoregulatory, anti-oxidative and anti-tumor activities. …
Matched Description: … Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline ... in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products and ... Polydatin possesses anti-inflammatory, immunoregulatory, anti-oxidative and anti-tumor activities. …
Etoposide
A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division,...
Approved
Matched Synonyms: … 4-demethylepipodophyllotoxin β-D-ethylideneglucoside ... )furo(3',4'':6,7)naptho-(2,3-d)-1,3-dioxol-6(5aH)-one ... 4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside) …
Matched Iupac: … (10R,11R,15R,16S)-16-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin …
Matched Description: … Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. ... This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. ... Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Dom-etoposide ... EPOSIN CONCENTRADO PARA SOLUCION DE INFUSION DE 20 MG/ML …
Matched Iupac: … (10R,11R,15R,16S)-16-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin …
Matched Description: … Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. ... This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. ... Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Dom-etoposide ... EPOSIN CONCENTRADO PARA SOLUCION DE INFUSION DE 20 MG/ML …
{4-[(CARBOXYMETHOXY)CARBONYL]-3,3-DIOXIDO-1-OXONAPHTHO[1,2-D]ISOTHIAZOL-2(1H)-YL}ACETIC ACID
Experimental
Matched Name: … {4-[(CARBOXYMETHOXY)CARBONYL]-3,3-DIOXIDO-1-OXONAPHTHO[1,2-D]ISOTHIAZOL-2(1H)-YL}ACETIC ACID …
Matched Iupac: … 2-[2-(carboxymethyl)-1,3,3-trioxo-1H,2H-3lambda6-naphtho[1,2-d][1,2]thiazole-4-carbonyloxy]acetic acid …
Matched Iupac: … 2-[2-(carboxymethyl)-1,3,3-trioxo-1H,2H-3lambda6-naphtho[1,2-d][1,2]thiazole-4-carbonyloxy]acetic acid …
Protriptyline
Protriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, protriptyline does not affect mood or arousal, but may cause sedation. In depressed individuals, protriptyline exerts a positive...
Approved
Matched Synonyms: … 5-(3-methylaminopropyl)-5H-dibenzo[a,d]cycloheptene ... 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine ... N-methyl-5H-dibenzo[a,d]cycloheptene-5-propanamine …
Matched Description: … TCAs also block histamine H1 receptors, alpha1-adrenergic receptors and muscarinic ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... In addition, TCAs down-regulate cerebral cortical β-adrenergic receptors and sensitize post-synaptic …
Matched Description: … TCAs also block histamine H1 receptors, alpha1-adrenergic receptors and muscarinic ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... In addition, TCAs down-regulate cerebral cortical β-adrenergic receptors and sensitize post-synaptic …
Cyproheptadine
Cyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors. It is used primarily to treat allergic symptoms, though it is perhaps more notable for its use in appetite stimulation and its off-label use in the treatment of serotonin syndrome.
Approved
Matched Synonyms: … 1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)piperidine ... 4-Dibenzo[a,d]cyclohepten-5-ylidene-1-methyl-piperidine ... 4-(5-dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine …
Matched Description: … Cyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors. ... treat allergic symptoms, though it is perhaps more notable for its use in appetite stimulation[L32519] and …
Matched Description: … Cyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors. ... treat allergic symptoms, though it is perhaps more notable for its use in appetite stimulation[L32519] and …
Displaying drugs 1101 - 1125 of 1847 in total