Displaying drugs 1126 - 1150 of 1231 in total
Cefixime
Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Investigational
Matched Synonyms: … Cefixime anhydrous …
Matched Description: … , and meningitis. ... a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and ... through inhibition of essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and …
Matched Salts name: … Cefixime trihydrate …
Matched Categories: … cefixime and ornidazole ... cefixime and azithromycin …
Matched Products: … CEFIXIME TRIHYDRATE …
Matched Description: … , and meningitis. ... a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and ... through inhibition of essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and …
Matched Salts name: … Cefixime trihydrate …
Matched Categories: … cefixime and ornidazole ... cefixime and azithromycin …
Matched Products: … CEFIXIME TRIHYDRATE …
Manganese gluconate
Manganese gluconate is a manganese salt of gluconic acid with the chemical formula C12H22MnO14 x 2H2O. It is typically obtained by reacting manganese carbonate with gluconic acid in aqueous medium and then crystallizing the product to form a slightly pink powder. Manganese gluconate is a direct ingredient in food substances...
Approved
Matched Synonyms: … Manganese gluconate anhydrous …
Matched Description: … It is typically obtained by reacting manganese carbonate with gluconic acid in aqueous medium and then …
Matched Mixtures name: … Cal-mag Plus K, Mn and Zn Caplets ... Multivitamins and Minerals for Young Men ... Multivitamins and Minerals for Young Women …
Matched Description: … It is typically obtained by reacting manganese carbonate with gluconic acid in aqueous medium and then …
Matched Mixtures name: … Cal-mag Plus K, Mn and Zn Caplets ... Multivitamins and Minerals for Young Men ... Multivitamins and Minerals for Young Women …
Florbetapir (18F)
Florbetapir (18F) is a radiopharmaceutical compound containing the radionuclide fluorine-18 bound to the compound florbetapir, a molecule that binds with high affinity to beta amyloid plaque, a peptide that plays a key role in Alzheimer's Disease pathogenesis. Marketed as the product Amyvid, florbetapir 18F is indicated for positron emission tomography...
Approved
Investigational
Matched Synonyms: … florbetapir-fluorine-18 …
Matched Description: … density in adult patients with cognitive impairment who are being evaluated for Alzheimer's Disease (AD) and ... Florbetapir (18F) is a radiopharmaceutical compound containing the radionuclide fluorine-18 bound to ... The radionucleide fluorine-18 was chosen as it has a half life of 110 minutes allowing it to accumulate …
Matched Categories: … Fluorine Radioisotopes …
Matched Description: … density in adult patients with cognitive impairment who are being evaluated for Alzheimer's Disease (AD) and ... Florbetapir (18F) is a radiopharmaceutical compound containing the radionuclide fluorine-18 bound to ... The radionucleide fluorine-18 was chosen as it has a half life of 110 minutes allowing it to accumulate …
Matched Categories: … Fluorine Radioisotopes …
MRK-003
MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. It is the preclinical analog of MK-0752, a drug in clinical development.
Investigational
Matched Synonyms: … 1-yl]prop-1-enyl]spiro[1,2,5-thiadiazolidine-4,13'-tricyclo[8.2.1.03,8]trideca-3(8),4,6-triene] 1,1-dioxide …
Matched Description: … MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. …
Matched Categories: … Gamma Secretase Inhibitors and Modulators …
Matched Description: … MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. …
Matched Categories: … Gamma Secretase Inhibitors and Modulators …
Fludeoxyglucose (18F)
Fludeoxyglucose F 18 Injection is a positron emitting radiopharmaceutical containing no-carrier added radioactive 2-deoxy-2-[18F]fluoro-D-g1ucose, which is used for diagnostic purposes in conjunction with Positron Emission Tomography (PET). It is administered by intravenous injection.
Approved
Investigational
Matched Synonyms: … Fluorine (18F) fludeoxyglucose …
Matched Categories: … Indicators and Reagents …
Matched Categories: … Indicators and Reagents …
Amifostine
A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
Approved
Investigational
Matched Synonyms: … Amifostine anhydrous …
Matched Description: … It causes splenic vasodilation and may block autonomic ganglia. …
Matched Salts name: … Amifostine trihydrate …
Matched Description: … It causes splenic vasodilation and may block autonomic ganglia. …
Matched Salts name: … Amifostine trihydrate …
Tegavivint
Investigational
Matched Synonyms: … 9,10-anthracenedione, 2,7-bis(((3r,5s)-3,5-dimethyl-1-piperidinyl)sulfonyl)-, 9,10-dioxime, rel- …
Ferrous gluconate
Approved
Matched Synonyms: … Ferrous gluconate anhydrous ... Iron(II) gluconate, anhydrous …
Matched Mixtures name: … Somarexin and C 1000 ... Magnum-75 Vitamin and Mineral Supplement …
Matched Categories: … Blood and Blood Forming Organs ... ferrous gluconate and folic acid …
Matched Mixtures name: … Somarexin and C 1000 ... Magnum-75 Vitamin and Mineral Supplement …
Matched Categories: … Blood and Blood Forming Organs ... ferrous gluconate and folic acid …
Dasatinib
Dasatinib is an orally available multikinase inhibitor indicated for the treatment of Philadelphia chromosome (Ph)-positive leukemias.[A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region (BCR) gene transcribe the chimeric protein...
Approved
Investigational
Matched Synonyms: … Anhydrous dasatinib ... Dasatinib anhydrous ... dasatinib (anhydrous) …
Matched Description: … pathogenesis of CML and 15-30% of ALL cases. ... A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and ... acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region (BCR …
Matched Salts name: … Dasatinib monolauryl sulfate …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … pathogenesis of CML and 15-30% of ALL cases. ... A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and ... acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region (BCR …
Matched Salts name: … Dasatinib monolauryl sulfate …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Dexamethasone acetate
Commonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions.[T797,L10695,L14348] Developed in 1957, dexamethasone is structurally similar to other corticosteroids such as hydrocortisone and prednisolone. Dexamethasone acetate has largely been replaced by dexamethasone phosphate and...
Approved
Investigational
Vet approved
Matched Synonyms: … Dexamethasone acetate anhydrous ... Dexamethasone acetate, anhydrous …
Matched Description: … [A188724] Dexamethasone acetate has largely been replaced by [dexamethasone] phosphate and continues ... previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and ... one-third in patients on oxygen therapy and mechanical ventilation, respectively. …
Matched Description: … [A188724] Dexamethasone acetate has largely been replaced by [dexamethasone] phosphate and continues ... previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and ... one-third in patients on oxygen therapy and mechanical ventilation, respectively. …
Piroxicam
A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.
Approved
Investigational
Matched Synonyms: … 4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazin-3-caboxyamid-1,1-dioxid …
Matched Description: … osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. ... non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Description: … osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. ... non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Zoledronic acid
Zoledronic acid, or CGP 42'446, is a third generation, nitrogen containing bisphosphonate similar to ibandronic acid, minodronic acid, and risedronic acid. Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone.[L13712,L13715,L13721] Zoledronic acid...
Approved
Matched Synonyms: … Anhydrous Zoledronic Acid ... Zoledronic Acid Anhydrous ... Zoledronic Acid, Anhydrous …
Matched Description: … third generation, nitrogen containing bisphosphonate similar to [ibandronic acid], [minodronic acid], and ... [A203111] Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia ... of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone. …
Matched Categories: … zoledronic acid, calcium and colecalciferol, sequential ... Drugs Affecting Bone Structure and Mineralization …
Matched Description: … third generation, nitrogen containing bisphosphonate similar to [ibandronic acid], [minodronic acid], and ... [A203111] Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia ... of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone. …
Matched Categories: … zoledronic acid, calcium and colecalciferol, sequential ... Drugs Affecting Bone Structure and Mineralization …
Cefadroxil
Long-acting, broad-spectrum, water-soluble, cephalexin derivative.
Approved
Vet approved
Withdrawn
Matched Synonyms: … Cefadroxil anhydrous …
Matched Salts name: … Cefadroxil sodium …
Matched Salts name: … Cefadroxil sodium …
Tripotassium (1R)-4-biphenyl-4-yl-1-phosphonatobutane-1-sulfonate
Experimental
Matched Name: … Tripotassium (1R)-4-biphenyl-4-yl-1-phosphonatobutane-1-sulfonate …
Matched Iupac: … potassium (1R)-4-{[1,1'-biphenyl]-4-yl}-1-[bis(potassiooxy)phosphoryl]butane-1-sulfonate …
Matched Iupac: … potassium (1R)-4-{[1,1'-biphenyl]-4-yl}-1-[bis(potassiooxy)phosphoryl]butane-1-sulfonate …
[(2R,3S,4R,5R)-5-(4-acetonyl-3-carbamoyl-pyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphate
Experimental
Matched Name: … [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphate …
Cyclosporine
Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus Beauveria nivea. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products...
Approved
Investigational
Vet approved
Matched Description: … treat various inflammatory and autoimmune conditions. ... calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and ... [A174049] Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Medications that reduce magnesium levels …
Matched Products: … Cyclosporine/Chondroitin Sulfate PF …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Medications that reduce magnesium levels …
Matched Products: … Cyclosporine/Chondroitin Sulfate PF …
Nevirapine
A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. Structurally, nevirapine belongs to the dipyridodiazepinone chemical class.
Approved
Matched Synonyms: … Nevirapine anhydrous ... Nevirapine, anhydrous …
Matched Description: … combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and …
Matched Mixtures name: … Lamivudine, Nevirapine, and Zidovudine ... LAMIVUDINE, NEVIRAPINE AND ZIDOVUDINE TABLETS (150/200/300 mg) …
Matched Categories: … stavudine, lamivudine and nevirapine ... zidovudine, lamivudine and nevirapine ... Metabolic Side Effects of Drugs and Substances …
Matched Description: … combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and …
Matched Mixtures name: … Lamivudine, Nevirapine, and Zidovudine ... LAMIVUDINE, NEVIRAPINE AND ZIDOVUDINE TABLETS (150/200/300 mg) …
Matched Categories: … stavudine, lamivudine and nevirapine ... zidovudine, lamivudine and nevirapine ... Metabolic Side Effects of Drugs and Substances …
Cephalexin
Cephalexin is the first of the first generation cephalosporins.[A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.[A179083,Label] Cephalexin was approved by the FDA on 4 January 1971.
Approved
Investigational
Vet approved
Matched Synonyms: … Anhydrous cefalexin ... Cefalexin anhydrous ... Anhydrous cephalexin …
Matched Description: … [A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. …
Matched Salts name: … Cefalexin sodium …
Matched Categories: … Medications that reduce magnesium levels …
Matched Description: … [A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. …
Matched Salts name: … Cefalexin sodium …
Matched Categories: … Medications that reduce magnesium levels …
Lanthanum carbonate
Lanthanum carbonate is a phosphate binder marketed under the trade name Fosrenol by Shire Pharmaceuticals. It is a large pill that requires thorough chewing to avoid choking and other gastrointestinal adverse effects. It is used to treat elevated phosphate levels, primarily in patients with chronic kidney disease, by binding to...
Approved
Matched Synonyms: … Lanthanum carbonate anhydrous …
Matched Description: … binding to dietary phosphate and preventing its absorption in the intestine. ... It is a large pill that requires thorough chewing to avoid choking and other gastrointestinal adverse ... Lanthanum carbonate is a phosphate binder marketed under the trade name _Fosrenol_ by Shire Pharmaceuticals …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia ... Phosphate Binder ... Phosphate-removing Agents …
Matched Description: … binding to dietary phosphate and preventing its absorption in the intestine. ... It is a large pill that requires thorough chewing to avoid choking and other gastrointestinal adverse ... Lanthanum carbonate is a phosphate binder marketed under the trade name _Fosrenol_ by Shire Pharmaceuticals …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia ... Phosphate Binder ... Phosphate-removing Agents …
2-deoxy-2-fluoro-alpha-D-mannosyl fluoride
Experimental
Matched Name: … 2-deoxy-2-fluoro-alpha-D-mannosyl fluoride …
Gallium nitrate
Gallium nitrate is a nitrate salt of DB14524, a heavy metal that has been used as a diagnostic agent. Gallium nitrate is reported to possess antiresorptive and hypocalcemic effects on bone. GANITE, a product of gallium nitrate previously used to treat cancer-related hypercalcemia, was discontinued from marketing in the US...
Approved
Investigational
Matched Synonyms: … Gallium nitrate (anhydrous) …
Matched Description: … [A260816] Gallium nitrate is reported to possess antiresorptive and hypocalcemic effects on bone. ... cancer-related hypercalcemia, gallium nitrate has been studied in arthritis, autoimmune disorders, and …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Calcium Resorption Inhibitor ... Medications that reduce magnesium levels …
Matched Description: … [A260816] Gallium nitrate is reported to possess antiresorptive and hypocalcemic effects on bone. ... cancer-related hypercalcemia, gallium nitrate has been studied in arthritis, autoimmune disorders, and …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Calcium Resorption Inhibitor ... Medications that reduce magnesium levels …
Displaying drugs 1126 - 1150 of 1231 in total