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Displaying drugs 1151 - 1175 of 1574 in total
PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.
Investigational
Matched Synonyms: … Benzenesulfonic acid, 2-methyl-5-nitro-, 2-((6-bromoimidazo(1,2-a)pyridin-3-yl)methylene)-1-methylhydrazide …
Matched Iupac: … N'-[(E)-{6-bromoimidazo[1,2-a]pyridin-3-yl}methylidene]-N,2-dimethyl-5-nitrobenzene-1-sulfonohydrazide …
Matched Description: … PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.[A253097] …
GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH-dependent manner
Investigational
Matched Synonyms: … recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH dependent …
Matched Description: … in a pH-dependent manner ... GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin …
Tovinontrine is an orally administered, highly selective phosphodiesterase 9 (PDE9) small molecule inhibitor. Tovinontrine is under investigation in clinical trial NCT04474314 (A Study of IMR-687 in Subjects With Sickle Cell Disease).
Investigational
Matched Synonyms: … 6-((3S,4S)-4-METHYL-1-(2-PYRIMIDINYLMETHYL)-3-PYRROLIDINYL)-3-(TETRAHYDRO-2H-PYRAN-4-YL)IMIDAZO(1,5-A) ... 6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3- tetrahydropyran-4-yl-7H-imidazo[1,5-a] ... 6-[(3S,4S-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3-tetrahydropyran-4-yl-7H-imadazo[1,5-a]pyrazin …
Matched Iupac: … 6-[(3S,4S)-4-methyl-1-[(pyrimidin-2-yl)methyl]pyrrolidin-3-yl]-3-(oxan-4-yl)-7H,8H-imidazo[1,5-a]pyrazin …
Matched Description: … Tovinontrine is an orally administered, highly selective phosphodiesterase 9 (PDE9) small molecule inhibitor ... Tovinontrine is under investigation in clinical trial NCT04474314 (A Study of IMR-687 in Subjects With …
Butenafine hydrochloride is a synthetic benzylamine antifungal agent. Butenafine's mechanism of action is believed to involve the synthesis inhibition of sterols. In particular, butenafine acts to inhibit the activity of the squalene epoxidase enzyme that is essential in the formation of sterols necessary for fungal cell membranes.
Approved
Matched Description: … Butenafine hydrochloride is a synthetic benzylamine antifungal agent. …
Matched Products: … Tinactin Once-A-day Cream …
Epinastine is used for the prevention of itching associated with allergic conjunctivitis. It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and H2-receptors to...
Approved
Investigational
Matched Synonyms: … 3-amino-9,13b-dihydro-1H-dibenz(c,f)imidazo(1,5-a)azepine …
Matched Description: … H2-receptors to stop itching and provide lasting protection, and 3. prevents the release of proinflammatory ... cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and ... It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells …
Matched Categories: … Decongestants and Antiallergics …
Etizolam is a thienodiazepine which is chemically related to benzodiazepine (BDZ) drug class; it differs from BDZs in having a benzene ring replaced with a thiophene ring. It is an agonist at GABA-A receptors and possesses amnesic, anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. Initially introduced in 1983...
Experimental
Matched Synonyms: … 4-(o-Chlorophenyl)-2-ethyl-9-methyl-6H-thieno(3,2-f)-s-triazolo(4,3-a)(1,4)diazepine …
Matched Description: … It is an agonist at GABA-A receptors and possesses amnesic, anxiolytic, anticonvulsant, hypnotic, sedative ... Initially introduced in 1983 in Japan as treatment for neurological conditions such as anxiety and sleep ... and skeletal muscle relaxant properties. …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives …
Antineoplaston A10 has been used in trials studying the treatment of Sarcoma, Lymphoma, Lung Cancer, Liver Cancer, and Kidney Cancer, among others.
Investigational
Matched Synonyms: … Antineoplaston A 10 …
Matched Name: … Antineoplaston A10
Matched Description: … Liver Cancer, and Kidney Cancer, among others. ... Antineoplaston A10 has been used in trials studying the treatment of Sarcoma, Lymphoma, Lung Cancer, …
Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow [FDA Label]. Epoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO...
Approved
Matched Description: … The biosimilar is approved by the FDA and EMA as a safe, effective and affordable biological product ... and displays equivalent clinical efficacy, potency, and purity to the reference product [A7504]. ... States, followed by other alfa and beta formulations. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Intercellular Signaling Peptides and Proteins …
Matched Products: … EXETIN-A ... EPO STADA 2000IU/0.6ml Solution for Injection in a Pre-filled Syringe ... EPO STADA 4000IU/0.4ml Solution for Injection in a Pre-filled Syringe …
Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for treatment of hepatitis B. It is ineffective against HIV-1. Adefovir dipivoxil is the diester prodrug of adefovir.
Approved
Investigational
Matched International brands: … A Di Xian ... A Gan Ding …
Matched Description: … Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered …
Matched Categories: … Nucleosides and Nucleotides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
Matched Products: … Aa-adefovir …
Tetanus Immune Globulin is manufactured from human plasma [FDA Label]. It contains antibodies against tetanus toxoid and is primarily used as prophylaxis against tetanus in wounded patients.
Approved
Matched Synonyms: … Human clostridium tetani toxoid immune globulin …
Matched Description: … It contains antibodies against tetanus toxoid and is primarily used as prophylaxis against tetanus in …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Investigational
Matched Synonyms: … 2-amino-n-(4-(5-oxo-7-(piperazin-1-yl)-5h-(1,3,4)thiadiazolo(3,2-a)pyrimidin-2-yl)pyridin-2-yl)acetamide ... Acetamide, 2-amino-n-(5-(5-oxo-7-(1-piperazinyl)-5h-1,3,4-thiadiazolo(3,2- a)pyrimidin-2-yl)-3-pyridinyl …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Hong Kong/4801/2014 (H3N2) recombinant hemagglutinin antigen …
Matched Description: … There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A virus A/West Virginia/30/2022 (H1N1) Recombinant Hemagglutinin Antigen …
Matched Description: … In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... There are three basic types of vaccines available: inactivated influenza vaccine (IIV), live attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
First-in-class potent and selective inhibitor of the BRD4 signaling pathway.
Investigational
Matched Synonyms: … (s)-(+)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin ... 6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-trimethyl ... Tert-butyl 2-((6s)-4-(4-chlorophenyl)-2,3,9-trimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin …
Matched Description: … First-in-class potent and selective inhibitor of the BRD4 signaling pathway.[A252967] …
Desoxyribonuclease is a crystalline enzyme that aids in the digestion of the thymus nucleic acid. The mechanism of action of the enzyme involves the splitting of thymus nucleic acid into fragments approaching the size of tetranucleotides without the release of free phosphoric acid. The enzyme's cofactor is reported to be...
Approved
Matched Synonyms: … Deoxyribonuclease A
Matched Description: … Desoxyribonuclease is a crystalline enzyme that aids in the digestion of the thymus nucleic acid. ... The mechanism of action of the enzyme involves the splitting of thymus nucleic acid into fragments approaching …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... fibrinolysin and desoxyribonuclease …
Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to...
Approved
Investigational
Matched Synonyms: … ((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo …
Matched Description: … [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic ... [L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002. ... Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. …
Matched Categories: … Drugs that are Mainly Renally Excreted …
Matched Products: … ERTAPENEM ACS DOBFAR ... ERTAPENEM 1G/VIAL POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …
Tideglusib is under the investigation for the development of treatments for Alzheimer's disease and for progressive supranuclear palsy. It is reported to be a potent anti-inflammatory and neuroprotective that is a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3). Tideglusib is being developed by the Spanish pharmaceutic company Zeltia...
Investigational
Withdrawn
Matched Synonyms: … 4-BENZYL-2-(A-NAPHTYL)-1,2,4-THIADIAZOLIDINE-3,5-DIONE …
Matched Description: … It is reported to be a potent anti-inflammatory and neuroprotective that is a non-ATP competitive inhibitor ... Tideglusib is under the investigation for the development of treatments for Alzheimer's disease and for ... [A31601] Tideglusib is being developed by the Spanish pharmaceutic company Zeltia group and its current …
Experimental
Investigational
Matched Synonyms: … Combrestatin A4 ... Combretastatin A-4 ... 2'-deoxycombretastatin A1
Matched Name: … Combretastatin A4
Meningococcal group Y polysaccharide is group-specific polysaccharide antigens extracted and purified from Neisseria meningitidis serogroup Y. N. meningitidis is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia. It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup Y.
Approved
Experimental
Investigational
Matched Synonyms: … Neisseria meningitidis group Y polysaccharide antigen, A
Matched Description: … *N. meningitidis* is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia ... Meningococcal group Y polysaccharide is group-specific polysaccharide antigens extracted and purified ... It is subcutaneously administered as an active immunization against the invasive meningococcal disease …
Matched Mixtures name: … Menveo Powder and Solution for Solution for Injection ... NIMENRIX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... Nimenrix Powder and Solvent for Solution for Injection …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/California/7/2009 (H1N1) recombinant hemagglutinin antigen …
Matched Description: … There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Uruguay/716/2007(H3N2) antigen (formaldehyde inactivated) …
Matched Description: … There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Brisbane/59/2007 (H1N1) antigen (formaldehyde inactivated) …
Matched Description: … There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Brisbane/59/2007(H1N1) antigen (propiolactone inactivated) …
Matched Description: … There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Hawaii/70/2019 (H1N1) recombinant hemagglutinin antigen …
Matched Description: … There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A virus A/Darwin/6/2021 (H3N2) recombinant hemagglutinin antigen …
Matched Description: … In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... There are three basic types of vaccines available: inactivated influenza vaccine (IIV), live attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Displaying drugs 1151 - 1175 of 1574 in total