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Displaying drugs 11801 - 11825 of 11935 in total

Brifentanil

Brifentanil (also known as A-3331) is an analog of fentanyl, a potent opioid. This drug is classified as an opioid analgesic and was developed in the early 1990s. The effects of brifentanil are very similar to those of alfentanil, with strong but short lasting analgesia and sedation, and particularly notable...
Illicit
Matched Iupac: … N-[(3R,4S)-1-[2-(4-ethyl-5-oxo-4,5-dihydro-1H-1,2,3,4-tetrazol-1-yl)ethyl]-3-methylpiperidin-4-yl]-N- ... (2-fluorophenyl)-2-methoxyacetamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Lazertinib

Lazertinib is under investigation in clinical trial NCT04487080 (A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-small Cell Lung Cancer).
Investigational
Matched Iupac: … N-{5-[(4-{4-[(dimethylamino)methyl]-3-phenyl-1H-pyrazol-1-yl}pyrimidin-2-yl)amino]-4-methoxy-2-(morpholin ... -4-yl)phenyl}prop-2-enamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

BMS-813160

BMS-813160 is under investigation in clinical trial NCT03496662 (BMS-813160 With Nivolumab and Gemcitabine and Nab-paclitaxel in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC)).
Investigational
Matched Iupac: … N-[(1R,2S,5R)-5-(tert-butylamino)-2-[(3S)-3-({7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-yl}amino)-2 ... -oxopyrrolidin-1-yl]cyclohexyl]acetamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Gepotidacin

Gepotidacin has been used in trials studying the treatment of Gonorrhea, Infections, Bacterial, and Infections, Respiratory Tract.
Investigational
Matched Iupac: … (3R)-3-({4-[({2H,3H,4H-pyrano[2,3-c]pyridin-6-yl}methyl)amino]piperidin-1-yl}methyl)-1,4,7-triazatricyclo …
Matched Salts cas: … 1624306-20-2 …

Cefsulodin

Experimental
Matched Iupac: … oct-2-en-3-yl]methyl}pyridin-1-ium ... 4-carbamoyl-1-{[(6R,7R)-2-carboxy-8-oxo-7-[(2R)-2-phenyl-2-sulfoacetamido]-5-thia-1-azabicyclo[4.2.0] …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Talampicillin

Experimental
Matched Iupac: … 3-oxo-1,3-dihydro-2-benzofuran-1-yl (2S,5R,6R)-6-[(2R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo- ... 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Ifebemtinib

Investigational
Matched Iupac: … -2-yl}amino)-N-(1-methylpiperidin-4-yl)benzamide ... 2-fluoro-5-methoxy-4-({4-[(2-methyl-3-oxo-2,3-dihydro-1H-isoindol-4-yl)oxy]-5-(trifluoromethyl)pyrimidin …

N-Methylmesoporphyrin

N-methylmesoporphyrin is a solid. This compound belongs to the porphyrins. These are compounds containing a fundamental skeleton of four pyrrole nuclei united through the alpha-positions by four methine groups to form a macrocyclic structure. This medication is known to target ferrochelatase.
Experimental
Matched Iupac: … 3-[20-(2-carboxyethyl)-10,15-diethyl-5,9,14,19,23-pentamethyl-21,22,23,24-tetraazapentacyclo[16.2.1.1 ... ^{3,6}.1^{8,11}.1^{13,16}]tetracosa-1,3(24),4,6,8,10,12,14,16(22),17,19-undecaen-4-yl]propanoic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

PF-03758309

PF-03758309 has been used in trials studying the treatment of Advanced Solid Tumors.
Investigational
Matched Iupac: … N-[(1S)-2-(dimethylamino)-1-phenylethyl]-6,6-dimethyl-3-({2-methylthieno[3,2-d]pyrimidin-4-yl}amino)- …
Matched Salts cas: … 1279034-84-2 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Rotigaptide

Rotigaptide is under investigation for the basic science of Heart Disease and Vascular Disease.
Investigational
Matched Iupac: … (2R)-N-(carbamoylmethyl)-2-(2-{[(2R,4S)-1-[(2R)-1-[(2R)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]pyrrolidine ... -2-carbonyl]-4-hydroxypyrrolidin-2-yl]formamido}acetamido)propanamide …

ONT-093

ONT-093 is an orally bioavailable inhibitor of P-glycoprotein (P-gp). In pre-clinical studies, ONT-093 could inhibit P-gp and reverse multidrug resistance at nM concentrations with no effect on paclitaxel pharmacokinetics.
Investigational
Matched Iupac: … 4-(2-{4-[(1E)-3-ethoxyprop-1-en-1-yl]phenyl}-4-{4-[(propan-2-yl)amino]phenyl}-1H-imidazol-5-yl)-N-(propan ... -2-yl)aniline …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Dermatan sulfate

Experimental
Matched Iupac: … (2R,3S,4S,5R,6R)-6-{[(2R,3R,4R,5R,6R)-3-acetamido-2-hydroxy-6-(hydroxymethyl)-5-(sulfonatooxy)oxan-4- ... yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylate …

Soraphen A

Experimental
Matched Iupac: … 1,17-dihydroxy-10,11,18-trimethoxy-2,14,16-trimethyl-5-phenyl-4,19-dioxabicyclo[13.3.1]nonadec-12-en-3- …

5'-O-(L-Threonylsulfamoyl)adenosine

Experimental
Matched Iupac: … )amino]-3-hydroxybutan-1-one ... (2S,3R)-2-amino-1-[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}sulfonyl …

Nitrocefin

Nitrocefin is a chromogenic cephalosporin substrate used to detect the presence of beta-lactamase enzymes, an important mediator of bacterial antibiotic resistance. While other detection methods exist, such as PCR, nitrocefin allows for rapid detection using few materials and inexpensive equipment.
Experimental
Matched Iupac: … (6R,7R)-3-[(E)-2-(2,4-dinitrophenyl)ethenyl]-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo ... [4.2.0]oct-2-ene-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Atopaxar

Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome.
Investigational
Matched Iupac: … 1-[3-tert-butyl-4-methoxy-5-(morpholin-4-yl)phenyl]-2-(5,6-diethoxy-7-fluoro-1-imino-2,3-dihydro-1H-isoindol ... -2-yl)ethan-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

PF-06273340

Pf 06273340 is under investigation in clinical trial NCT01934738 (A Study to Evaluate Safety, Toleration and Time Course of Plasma Concentration of Multiple Oral Doses of PF-06273340 in Healthy Subjects of Two AgeGroups, Aged 18-55 Years (Group 1) and Aged 56-75 Years (Group 2)).
Investigational
Matched Iupac: … N-{5-[2-amino-7-(1-hydroxy-2-methylpropan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl]pyridin-3-yl}- ... 2-(5-chloropyridin-2-yl)acetamide …
Matched Description: … and Aged 56-75 Years (Group 2)). ... of Multiple Oral Doses of PF-06273340 in Healthy Subjects of Two AgeGroups, Aged 18-55 Years (Group 1) …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Salvinorin A

Salvinorin A has been investigated for the basic science of Pharmaceutical Preparations.
Investigational
Matched Iupac: … methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-dodecahydro …

Mibenratide

Mibenratide is under investigation in clinical trial NCT01798745 (A Study to Assess the Pharmacokinetics and Pharmacodynamics of JNJ-54452840 in Participants With Heart Failure and Anti-beta1-adrenergic Receptor Autoantibodies).
Investigational
Matched Iupac: … -4,7-bis(3-carbamimidamidopropyl)-22-(2-carbamoylethyl)-52-(carbamoylmethyl)-16,31,49-tris(carboxymethyl ... 3-[(1R,4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R,40S,43S,49S,52S,55S)-40-(4-aminobutyl)-28-benzyl ... hydroxyphenyl)methyl]-10,19-dimethyl-3,6,9,12,15,18,21,24,27,30,33,36,39,42,48,51,54,57-octadecaoxo-25-(propan-2- …

Odalasvir

Odalasvir has been used in trials studying the treatment of Hepatitis C, Chronic and Chronic Hepatitis C Infection.
Investigational
Matched Iupac: … methyl N-[(2S)-1-[(2S,3aS,7aS)-2-[6-(14-{2-[(2S,3aS,7aS)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl ... ),10,13-hexaen-5-yl)-1H-1,3-benzodiazol-2-yl]-octahydro-1H-indol-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate ... ]-octahydro-1H-indol-2-yl]-1H-1,3-benzodiazol-6-yl}tricyclo[8.2.2.2^{4,7}]hexadeca-1(12),4(16),5,7(15 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Pefcalcitol

Pefcalcitol has been investigated for the basic science of Psoriasis.
Investigational
Matched Iupac: … 2-[(1S)-1-[(3aS,7E,7aS)-7-{2-[(1Z,3S,5R)-3,5-dihydroxy-2-methylidenecyclohexylidene]ethylidene}-3a-methyl ... -3a,4,5,6,7,7a-hexahydro-1H-inden-3-yl]ethoxy]-N-(2,2,3,3,3-pentafluoropropyl)acetamide …

Volasertib

Volasertib has been used in trials studying the treatment of Leukemia, Neoplasms, Leukemia, Myeloid, Acute, Myelodysplastic Syndromes, and Leukemia, Monocytic, Acute, among others.
Investigational
Matched Iupac: … 4-{[(7R)-7-ethyl-5-methyl-6-oxo-8-(propan-2-yl)-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-[( ... 1r,4r)-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl]benzamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Cefatrizine

Experimental
Matched Iupac: … -5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-8-oxo-3-[(1H-1,2,3-triazol-4-ylsulfanyl)methyl] …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Uprifosbuvir

Uprifosbuvir is under investigation in clinical trial NCT02332707 (Efficacy and Safety of Grazoprevir (MK-5172) and Uprifosbuvir (MK-3682) With Elbasvir (MK-8742) or Ruzasvir (MK-8408) for Chronic Hepatitis C Genotype (GT)1 and GT2 Infection (MK-3682-011)).
Investigational
Matched Iupac: … propan-2-yl (2R)-2-{[(R)-{[(2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxy ... -4-methyloxolan-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate …
Matched Description: … Uprifosbuvir (MK-3682) With Elbasvir (MK-8742) or Ruzasvir (MK-8408) for Chronic Hepatitis C Genotype (GT)1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Coproporphyrin I

Experimental
Matched Iupac: … 3-[9,14,19-tris(2-carboxyethyl)-5,10,15,20-tetramethyl-21,22,23,24-tetraazapentacyclo[16.2.1.1^{3,6}.1 ... ^{8,11}.1^{13,16}]tetracosa-1(20),2,4,6(24),7,9,11,13(22),14,16,18-undecaen-4-yl]propanoic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 11801 - 11825 of 11935 in total