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Displaying drugs 101 - 125 of 3602 in total
Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and induces tumour cell death. Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to...
Approved
Matched Synonyms: … .,20-EPOXYTAX-11-ENE-2.ALPHA.,4,13.ALPHA. …
Matched Description: … and induces tumour cell death. ... [A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17 ... cabazitaxel can more readily penetrate the blood–brain barrier compared to other taxanes like [paclitaxel] and
Matched Categories: … Antineoplastic and Immunomodulating Agents ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …
Matched Products: … JEVTANA 60mg CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION ... JEVTANA (CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION) ... Cabazred 60mg/1.5ml Concentrate And Solvent For Solution For Infusion …
Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does not cross the blood-brain barrier. Due to its activity, carbidopa is always administered concomitantly with levodopa. An individual formulation containing solely carbidopa was generated to treat...
Approved
Matched Synonyms: … (-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid monohydrate ... (αS)-α-hydrazino-3,4-dihydroxy-α-methylbenzenepropanoic acid ... L-3-(3,4-dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid
Matched Iupac: … (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
Matched Description: … It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does ... approved product by the FDA containing only carbidopa was developed by Amerigens Pharmaceuticals Ltd and ... Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. …
Matched Mixtures name: … Carbidopa and Levodopa ... Carbidopa and Levodopa ... Carbidopa and Levodopa …
Matched Categories: … Drugs that are Mainly Renally Excreted ... Aromatic Amino Acid Decarboxylase Inhibitors ... Aromatic L-amino Acid Decarboxylase Inhibitors …
Matched Products: … Carbidopa and Levodopa ... Carbidopa and levodopa …
TN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human PKP2 gene.
Investigational
Matched Synonyms: … A native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type …
Matched Description: … TN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and
Sarocladium strictum allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, acremonium strictum ... Molds, rusts and smuts, cephalosporium acremonium ... Ae-cephalosporium acrimonium …
Matched Products: … Molds, Rusts and Smuts, Cephalosporium acremonium …
Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA . It is a structurally-related compound to DB02362 that absorbs UV-B rays to prevent photodamage. It penetrates human skin, and is shown to induce non-ligatable strand...
Approved
Matched Description: … Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in ... It penetrates human skin, and is shown to induce non-ligatable strand breaks on DNA _in vitro_ and mutagenic ... concentrations up to 8%, as regulated by the FDA [L2153]. …
Matched Mixtures name: … Sun and Ski Stick SPF 15 ... Aruba Aloe Lip Sunscreen and Moisturizer ... Phineas and Ferb Sun Smacker SPF 24 Berry Busted …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Acids, Carbocyclic ... Carboxylic Acids
Matched Products: … Hand and Body Lotion SPF 15 ... Green Tea and Ginkgo Moisturizer SPF 10 ... Medicated Lip Balm - Ont Top 8% …
Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the levorotatory form (levopanthenol). While pantothenic acid is optically active, only the dextrorotatory...
Approved
Matched Description: … Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an ... Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the ... Furthermore, it acts as a topical protectant, moisturizer, and has demonstrated anti-inflammatory properties …
Matched Mixtures name: … Therapytion Nokmosu Sensitive and Dry Hair ... Therapytion Nokmosu Neutral and oily Hair ... All New TS …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
Matched Products: … BABOR Baborganic Calm and Relax ... Roota Re V Tonic ... Roota Re F for men …
VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking the CD33 protein.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking …
Matched Description: … VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy …
Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as Fluoride ion F-18. Sodium fluoride's benefits on dental health were first observed in the 1930s, when individuals in communities with fluoridated...
Approved
Matched Synonyms: … Sodium fluoride …
Matched Name: … Sodium fluoride …
Matched Iupac: … sodium fluoride …
Matched Description: … Now, sodium fluoride may be found in a variety of gels, varnishes, rinses, toothpaste products, and fluoride ... , including dental care and radiographic imaging when it is used as [Fluoride ion F-18]. ... indicated that the use of fluoride to prevent and control dental caries is safe when used correctly and
Matched Mixtures name: … Perfect Choice 0.717% Root and Dentin Desens ... Sodium Fluoride and Vitamin D Drops ... Sodium Fluoride and Potassium Nitrate …
Matched Categories: … Alimentary Tract and Metabolism ... Mouthwashes and Gargles ... sodium fluoride ... sodium fluoride ... Sodium Compounds …
Matched Products: … Coral ... Top Quality Mfg APF ... Age Defying Fluoride and Liquid Calcium …
Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage.[A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. Molecular weights of PEGs vary...
Approved
Vet approved
Matched Description: … PEGs differ in their physical and chemical properties depending on their molecular weight: PEGs are liquids ... when molecular weights are <1000 and the molecule turns to waxy solids with increasing molecular weights ... [A190978] The most common preparations of PEGs include PEG 3350 and PEG 400. …
Matched Mixtures name: … Peg-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate and Ascorbic Acid ... Polyethylene Glycol-3350, Sodium Chloride, Potassium Chloride and Sodium Bicarbonate ... PEG-3350, sodium chloride, sodium bicarbonate and potassium chloride …
Matched Categories: … Alimentary Tract and Metabolism ... Compounds used in a research, industrial, or household setting …
Matched Products: … Up and Up Powderlax ... Berkley and Jensen Clearlax ... Polyethylene Glycol 3350 and Electrolytes …
Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched International brands: … AK-Dilate ... AK-Nefrin …
Matched Description: … the pupil,[L9413] and induce local vasoconstriction. ... Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate …
Matched Mixtures name: … Core Values Tussin CF ... Top Care Flu and Sore Throat ... Comtrex Cough and Cold Day/Night …
Matched Categories: … Adrenergic and Dopaminergic Agents ... Mydriatics and Cycloplegics ... Decongestants and Antiallergics ... phenylephrine and ketorolac ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … First Aid Direct Nasal and Sinus Decongestant ... Up and Up Sinus PE ... CareOne Cold and Sinus …
Exenatide is a glucagon-like peptide-1 (GLP-1) analog . It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows gastric emptying to improve glycemic control . Exenatide was given FDA approval on April 28, 2005 . It is available as immediate- and extended-release formulations.[L42685,L42690] Bydureon, the brand...
Approved
Investigational
Matched Description: … It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows ... It is available as immediate- and extended-release formulations. ... Exenatide is a glucagon-like peptide-1 (GLP-1) analog[L42690]. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Fluids and Secretions ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … BYDUREON 2 mg powder and solvent for prolonged-release suspension for injection ... BYDUREON POWDER AND SOLVENT FOR PROLONGED-RELEASE SUSPENSION FOR INJECTION IN PRE-FILLED PEN 2MG …
Guaifenesin possesses a storied history, having been originally formally approved by the US FDA in 1952 and continues to be one of very few - if not perhaps the only drug that is readily available and used as an expectorant . Since that time the agent has been a combination...
Approved
Investigational
Vet approved
Matched Description: … over-the-counter cough and cold products and is currently a widely available over-the-counter generic ... and continues to be one of very few - if not perhaps the only drug that is readily available and used ... to be safe and effective in children under the age of 6 years [F4525]. …
Matched Mixtures name: … TRIFEN 100 ML SUS. ... Topco tussin cf max ... Core Values Tussin CF …
Matched Categories: … Cough and Cold Preparations …
Matched Products: … Up and Up Mucus Relief ... Up and Up mucus relief ... Mucus and Chest Congestion …
Anti-inhibitor coagulant complex, also known as FEIBA (factor eight inhibitor bypassing activity), contains several proteins involved in the prothrombinase complex. It is used to control bleeding in hemophilia A and B patients with inhibitors.
Approved
Investigational
Matched Description: … It is used to control bleeding in hemophilia A and B patients with inhibitors. ... Anti-inhibitor coagulant complex, also known as FEIBA (factor eight inhibitor bypassing activity), contains …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … FEIBA (Factor VIII Inhibitor Bypassing Activity) 25U/ml Powder and solvent for solution for infusion ... FEIBA (Factor VIII Inhibitor Bypassing Activity) 50U/ml Powder and solvent for solution for infusion …
Chenopodium album pollen is the pollen of the Chenopodium album plant. Chenopodium album pollen is mainly used in allergenic testing.
Approved
Matched Products: … Pollens - Weeds and Garden Plants, Lamb Quarters Chenopodium album ... Pollens - Weeds and Garden Plants, Lambs Quarters Chenopodium album ... Center-AL - Chenopodium Album Pollen …
A vitamin-like antioxidant.
Approved
Investigational
Nutraceutical
Matched Synonyms: … (+)-alpha-Lipoic acid ... Alpha lipoic acid ... alpha-Lipoic acid
Matched Name: … Lipoic acid
Matched Iupac: … 5-[(3R)-1,2-dithiolan-3-yl]pentanoic acid
Matched Description: … A vitamin-like antioxidant. …
Matched Mixtures name: … Essential Pro ALPHA-G Q10 Capsule ... Protect Cardio AF ... SURBEX Natopherol ALA PLUS …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products ... Sulfur Compounds ... Coenzymes
Matched Products: … NUTRABIOTICS A-LIPOR ® ACIDO ALFA LIPOICO ... ALPHA LIPOIC ACID CAPSULE ... LIPO-X (ALPHA LIPOIC ACID 50MG) …
Fibrinogen concentrate (human) is a hematological agent. It works by replacing a certain protein in the blood that helps with blood clotting. Fibrinogen (factor I) is a soluble plasma glycoprotein with a molecular weight of about 340 kDa. It is a physiological substrate for three enzymes: plasmin, factor XIIIa and...
Approved
Matched Description: … It is a physiological substrate for three enzymes: plasmin, factor XIIIa and thrombin. ... acute bleeding episodes in patients with congenital fibrinogen deficiency, including afibrinogenemia and ... Fibrinogen (factor I) is a soluble plasma glycoprotein with a molecular weight of about 340 kDa. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … FIBRYGA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL ... Fibryga 1g Powder and Solvent for Solution for Injection or Infusion …
Dendryphiella vinosa is a fungus which can provoke allergic reactions. Dendryphiella vinosa extract is used in allergenic testing.
Approved
Matched Description: … Dendryphiella vinosa is a fungus which can provoke allergic reactions. …
Matched Products: … Molds, Rusts and Smuts, Helminthosporium interseminatum …
Atacicept is a recombinant fusion protein combined with the extracellular ligand binding portion of TACI.
Investigational
Matched Synonyms: … Human Transmembrane Activator and CAML Interactor (TACI) Immunoglobulin G1 Fc Domain Fusion Protein ( …
Matched Description: … Atacicept is a recombinant fusion protein combined with the extracellular ligand binding portion of TACI …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Mesocricetus auratus skin or pelt is used in allergenic testing.
Approved
Matched Products: … Hamster Hair and Epithelia …
Cod, unspecified allergenic extract is used in allergenic testing.
Approved
Matched Products: … Food - Fish and Shellfish, Codfish Gadus callarias …
Approved
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with recombinant human fusion protein (MUCIN1 and Glutathione S Transferase …
AMG 424 is a novel, humanized, anti-CD3/CD38 bispecific monoclonal antibody being investigated for multiple myeloma.
Investigational
Matched Synonyms: … Humanized Bi-Specific Xmab(R) T Cell Recruiting Antibody Construct Directed Against Cd3 And Cd38 ... AMG-424 …
Matched Name: … AMG 424 …
Matched Description: … AMG 424 is a novel, humanized, anti-CD3/CD38 bispecific monoclonal antibody being investigated for multiple …
Investigational
Matched Synonyms: … FC-fusion bispecific antibody targeting extracellular domains II and IV of HER 2 and FC-fusion bispecific ... IgG1 antibody inhibiting PD-L1 and CTLA-4 …
Investigational
Matched Synonyms: … Attenuated autologous cancer cells and granulocyte macrophage colony stimulating factor in combination …
Nendratareotide uzatansine is a peptide-drug conjugate comprising a peptide analog of somatostatin conjugated to the cytotoxin mertansine.
Investigational
Matched Synonyms: … Peptide-drug conjugate combining [(Tyr3,Cys8) octreotate amide] and N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl …
Matched Description: … Nendratareotide uzatansine is a peptide-drug conjugate comprising a peptide analog of somatostatin conjugated …
Displaying drugs 101 - 125 of 3602 in total