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Displaying drugs 101 - 125 of 1256 in total
Guaifenesin possesses a storied history, having been originally formally approved by the US FDA in 1952 and continues to be one of very few - if not perhaps the only drug that is readily available and used as an expectorant . Since that time the agent has been a combination...
Approved
Investigational
Vet approved
Matched Description: … and continues to be one of very few - if not perhaps the only drug that is readily available and used ... over-the-counter cough and cold products and is currently a widely available over-the-counter generic ... cough/cold combinations are not known to be safe and effective in children under the age of 6 years …
Matched Mixtures name: … Topco tussin cf max ... Up and Up Daytime Vapor Ice Cold and Flu Nighttime Vapor Ice Cold and Flu ... Up and Up Daytime Vapor Ice Cold and Flu Nighttime Vapor Ice Cold and Flu …
Matched Categories: … Cough and Cold Preparations …
Matched Products: … Topco Mucus Relief ... Organ-I Nr ... Organ I Nr …
Mus musculus skin or pelt is used in allergenic testing.
Approved
Matched Synonyms: … house mouse skin extract …
Matched Name: … Mus musculus skin
Matched Description: … Mus musculus skin or pelt is used in allergenic testing. …
Matched Categories: … Increased IgG Production ... Non-Standardized Animal Skin Allergenic Extract …
Matched Products: … Mouse Hair and Epithelia ... Mus Musculus Skin
Carbamide peroxide, also known as urea-hydrogen peroxide, is a water-soluble, white crystalline solid compound consisting of hydrogen peroxide and urea. As it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products. Some adverse effects of carbamide peroxide as a dental bleaching agent include...
Approved
Matched Synonyms: … Urea dioxide
Matched Description: … As it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products ... It is available in OTC otic drugs as non-water, non-oil-based solutions used to soften, loosen and remove ... It may also alter enamel surface morphology via enamel mineral loss and surface roughening [A32336]. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Ear Wax Removal Drops Up and Up ... CareOne Earwax Removal Kit, Earwax and Bulb ... Family Wellness Earwax Removal Earwax and Bulb …
ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK).
Investigational
Matched Synonyms: … humanized immunoglobulin gamma 1 (IgG1) agonistic monoclonal antibody (mAb) that specifically targets and
Matched Description: … ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK). …
Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.
Approved
Investigational
Matched Description: … fibers and at nerve endings. ... Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve ... [A231219] It is commonly used for local anesthesia in many over the counter products. …
Matched Mixtures name: … Topco 4x Medicated Toothache and Gum Gel ... CARMEX Multi-Symptom 3 in 1 COLD Sore treatment External Analgesic Skin Protectant ... BLT Skin Cream …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Antipruritics and Local Anesthetics …
Matched Products: … SKINS DELAY Climax Control Benzocaine Gel ... Topex ... Orabase Benzocaine Purple Ice
TN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human PKP2 gene.
Investigational
Matched Synonyms: … A native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type
Matched Description: … TN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and ... the wild-type human PKP2 gene. …
Omalizumab is a recombinant DNA-derived humanized monoclonal antibody directed against human immunoglobulin E (IgE). IgE promotes the release of inflammatory mediators from mast cells and basophils during allergic and inflammatory reactions. By binding to IgE and neutralizing it, omalizumab reduces free IgE levels and prevents IgE from binding to its...
Approved
Investigational
Matched Description: … By binding to IgE and neutralizing it, omalizumab reduces free IgE levels and prevents IgE from binding ... [A39518] Omalizumab was first approved in the US in 2003 [A263507] and in Europe in 2005. ... [L50482] It is used to treat a range of immune and inflammatory conditions, including allergies, urticaria …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Anti-IgE ... Decreased IgE Activity ... IgE-directed Antibody Interactions …
Matched Products: … Xolair 75mg Powder and Solvent for Solution for Injection ... Xolair 150mg Powder and Solvent for Solution for Injection ... XOLAIR 150MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Investigational
Matched Synonyms: … Colostrum (bos taurus) ... Bovine Colostrum ... Colostrum bovine
Matched Name: … Bos taurus colostrum …
Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched Description: … the pupil,[L9413] and induce local vasoconstriction. ... [A187370] The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s ... [A187376] Phenylephrine was granted FDA approval in 1939.[L9413] …
Matched Mixtures name: … Top Care Flu and Sore Throat ... Topco tussin cf max ... Top Value Effervescent Cold Relief …
Matched Categories: … Adrenergic and Dopaminergic Agents ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Mydriatics and Cycloplegics ... Decongestants and Antiallergics ... phenylephrine and ketorolac …
Matched Products: … Up and Up nasal decongestant PE ... CareOne Cold and Sinus ... Up and Up Sinus PE …
Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis. This unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. During in...
Approved
Matched Synonyms: … PVP-I
Matched Description: … Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine ... Shelanski and M. V. Shelanski. ... Povidone-iodine was immediately marketed, and has since become the universally preferred iodine antiseptic …
Matched Mixtures name: … Jamshidi Bone Marrow Biopsy Tray ... BRAUNODERM (IN 250ML AND 1000ML PLASTIC) ... Physician EZ Use Joint Tunnel and Trigger Kit II
Matched Categories: … Antiseptics and Disinfectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Compounds used in a research, industrial, or household setting …
Matched Products: … 3M Skin and Nasal Antiseptic ... Antiseptic Patient Preoperative Skin Preparation and Surgical Hand Scrub ... Easy to break-off cleaning and disinfecting swabstick DFB-I
VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking the CD33 protein.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking …
Matched Description: … VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy …
Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential component of the coagulation cascade. Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) and purified from extraneous plasma-derived...
Approved
Matched Description: … results in the conversion of prothrombin to thrombin, and as a result, leads to the conversion of fibrinogen ... clotting cascade, and as a result, leads to easy bruising and bleeding. ... ], which is produced by recombinant DNA technology and is identical in sequence to endogenously produced …
Matched Mixtures name: … Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection ... Haemate P Powder and solvent for solution for injection or infusion …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250 IU ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 1000 IU
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Approved
Matched Description: … and ultimately blocks synaptic transmission. ... Nicotine is also important medically because of its presence in tobacco smoke. ... It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons …
Matched Mixtures name: … Nicorette and Aquafresh Fruit Chill and Extreme Clean Whitening …
Matched Categories: … Drugs Used in Addictive Disorders ... Drugs Used in Nicotine Dependence …
Matched Products: … Up and Up Cherry Ice Nicotine ... Up and Up Nicotine ... Up and Up Nicotine Polacrilex …
Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as Fluoride ion F-18. Sodium fluoride's benefits on dental health were first observed in the 1930s, when individuals in communities with fluoridated...
Approved
Matched Description: … , including dental care and radiographic imaging when it is used as [Fluoride ion F-18]. ... control dental caries is safe when used correctly and is highly effective in reducing the prevalence ... Now, sodium fluoride may be found in a variety of gels, varnishes, rinses, toothpaste products, and fluoride …
Matched Mixtures name: … Perfect Choice 0.717% Root and Dentin Desens ... Top. Gel ... Top Care Enamel Guard …
Matched Categories: … Alimentary Tract and Metabolism ... Mouthwashes and Gargles ... Compounds used in a research, industrial, or household setting …
Matched Products: … Walgreens Sulfate Free ... CloSYS Sulfate Free Fluoride ... BON SCENT Sparkling Tooth Wash …
The human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma glycoprotein involved in hemostasis. It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood vessel injury and stabilizing procoagulant factor VIII (FVIII). Exogenous sources of vWF...
Approved
Investigational
Matched Description: … It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood ... The human vWF is used to manage and control bleeding episodes in patients with von Willebrand disease ... [L1878] A recombinant form of vWF, [vonicog alfa], is also available to enhance production and avoid …
Matched Mixtures name: … Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection ... Haemate P Powder and solvent for solution for injection or infusion …
Matched Categories: … von Willebrand factor and coagulation factor VIII in combination ... Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … IMMUNATE 50 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... IMMUNATE 100 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... Willfact 1000 I.E. Pulver und Lösungsmittel zur Herstellung einer Injektionslösung …
Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-cov-2) Infection (COVID-19)).
Investigational
Matched Synonyms: … receptor and a mutant Fc fragment of human IGg1 and part of human IL1 receptor accessory protein ... Heterodimeric fusion protein that binds to IL-1 beta consisting of human extracellular domain of IL1
Matched Description: … Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of ... a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe …
Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and induces tumour cell death. Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to...
Approved
Matched Description: … [A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17 ... A260621] As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and ... penetrate the blood–brain barrier compared to other taxanes like [paclitaxel] and [docetaxel]. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … JEVTANA 60mg CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION ... JEVTANA (CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION) ... Concentrate and Solvent for Solution for Infusion 60mg/1.5ml …
Investigational
Matched Synonyms: … FC-fusion bispecific antibody targeting extracellular domains II and IV of HER 2 and FC-fusion bispecific ... IgG1 antibody inhibiting PD-L1 and CTLA-4 ... SERINE,371-ALANINE,408-LYSINE,410-VALINE), ANTI-(HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR HER2 DOMAIN IV
TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAE.
Investigational
Matched Synonyms: … Antibody drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload …
Matched Description: … and linker-payload MC-VC-PAB-MMAE. ... TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 …
Corn starch refers to the starch extracted from the corn grain that is commonly used as a food ingredient and chemical additive. Starch is any of a group of polysaccharides of the general formula (C6-H10-O5)n, composed of a long-chain polymer of glucose in the form of amylose and amylopectin. Starch...
Approved
Nutraceutical
Matched Description: … polymer of glucose in the form of amylose and amylopectin. ... Corn starch may be added in some food products as a thickening agent or anti-caking agent, and is sometimes ... found in topical drugs as a skin protectant. …
Matched Mixtures name: … Gold Bond Baby Cornstarch Plus …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Soothe and Cool Non-Caking Body ... Lotrimin Daily Sweat and Odor Control …
Investigational
Matched Synonyms: … Allogeneic umbilical cord blood (UCB) cell therapy product consisting of two cell fractions (CD34 enriched and ... ALLOGENEIC UMBILICAL CORD BLOOD-DERIVED HEMATOPOIETIC STEM AND PROGENITOR CELLS MGTA-456 …
Approved
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with recombinant human fusion protein (MUCIN1 and Glutathione S Transferase …
AMG 424 is a novel, humanized, anti-CD3/CD38 bispecific monoclonal antibody being investigated for multiple myeloma.
Investigational
Matched Synonyms: … Humanized Bi-Specific Xmab(R) T Cell Recruiting Antibody Construct Directed Against Cd3 And Cd38 …
Matched Description: … AMG 424 is a novel, humanized, anti-CD3/CD38 bispecific monoclonal antibody being investigated for multiple …
NTLA-2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger RNA (mRNA000042) encoding Cas9. It is an investigational therapy designed to knock out the target gene kallikrein B1 (KLKB1) to reduce plasma kallikrein activity, thereby preventing hereditary angioedema attacks.
Investigational
Matched Synonyms: … lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger …
Matched Description: … gene and messenger RNA (mRNA000042) encoding Cas9. ... It is an investigational therapy designed to knock out the target gene kallikrein B1 (KLKB1) to reduce ... NTLA-2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 …
Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for...
Approved
Investigational
Matched Iupac: … 3H-benzo[e]indol-2-ylidene]hepta-1,3,5-trien-1-yl}-1,1-dimethyl-3-(4-sulfonatobutyl)-1H-benzo[e]indol-3-ium
Matched Description: … Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. ... The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl …
Matched Mixtures name: … Icg
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Spy Agent Green Kit for Advanced Imaging Modality (aim) and Pinpoint ... Spy Agent Green Lymphatics Kit for Advanced Imaging Modality (aim) and Pinpoint ... IC-Green …
Displaying drugs 101 - 125 of 1256 in total