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Displaying drugs 101 - 125 of 708 in total
Experimental
Matched Synonyms: … 4-O-phosphono-L-threonic acid …
Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Approved
Matched Synonyms: … cyclo((4R)-4-(2-aminoethylcarbamoyloxy)-L-prolyl-L-phenylglycyl-D-tryptophyl-L-lysyl-4-O-benzyl-L-tyrosyl-L …
Matched Description: … It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Somatostatin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SIGNIFOR LAR(60 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... Signifor LAR 20mg powder and solvent for suspension for injection ... Signifor LAR 40mg powder and solvent for suspension for injection …
Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor VIII, the essential human blood clotting protein that is impaired in Hemophilia A. Moroctocog alfa is identical in sequence to endogenously produced Factor...
Approved
Matched Description: … for the prophylaxis and control of bleeding episodes. ... prevention of hemorrhagic episodes and for routine and surgical prophylaxis in patients with hemophilia ... Exogenous replacement of Factor VIII is currently the cornerstone of Hemophilia treatment and is used …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Xyntha 250 IU Powder and Solvent for Solution for Injection ... Xyntha 1000 IU Powder and Solvent for Solution for Injection ... Xyntha 500 IU Powder and Solvent for Solution for Injection …
Experimental
Matched Synonyms: … O-(N-Acetyl-alpha-neuraminosyl)-(2->3)-o-beta-D-galactopyranosyl-(1->4)-alpha-D-glucopyranose …
Matched Iupac: … }oxan-4-yl]oxy}-5-acetamido-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid ... 6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-{[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy
Experimental
Matched Synonyms: … 3-O-Methylglucose ... O(3)-methyl-D-glucose …
Matched Name: … 3-O-Methyl-d-glucose …
Approved
Matched Name: … Smallpox and Monkeypox Vaccine, Live, Non-replicating …
Pyrithione zinc, or zinc pyrithione or zinc pyridinethione, is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers. In the crystalline state, it exists as a centrosymmetric dimer. Due to its dynamic fungistatic and bacteriostatic properties, pyrithione zinc is used to treat...
Approved
Matched Description: … of proteins essential for fungal metabolism and growth [A27132]. ... Other uses of pyrithione zinc include additive in antifouling outdoor paints and algaecide. ... Dandruff is a common scalp disease affecting >40% of the world's adult population, and may be caused …
Matched Mixtures name: … Head and Shoulders Dual Sachets Full and Strong ... Head and Shoulders Dual Sachets Full and Strong ... Head and Shoulders Dual Pack Smooth and Silky …
Matched Products: … Head and Shoulders Old Spice ... Head and Shoulder Men Old Spice ... Head and Shoulders Men Old Spice …
Experimental
Matched Synonyms: … 5'-O-(L-Tyrosylsulfamoyl)adenosine …
Matched Iupac: … 6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}sulfonyl)amino]-3-(4-hydroxyphenyl)propan-1-one
Desvenlafaxine (O-desmethylvenlafaxine) is the 0-demetyhlated active metabolite of venlafaxine. Like its parent drug, desvenlafaxine is also an antidepressant belonging to the class of serotonin-norepinephrine reuptake inhibitor (SNRI) class.[A261266,A261266] It was approved by the FDA in 2008 for the treatment of adults with major depressive disorder (MDD).[L6016,A261271] MDD is a highly...
Approved
Investigational
Matched International brands: … Zyven-OD
Matched Synonyms: … ODV ... O-desmethylvenlafaxine …
Matched Description: … 16% in the US alone and 12.8% in Europe. ... [A261271] Desvenlafaxine has a very similar pharmacological, efficacy, and safety profile as [venlafaxine ... Although the exact mechanism of pathophysiology is still unknown, imbalances or deficiencies of monoamines …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors ... Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Tofersen is under an intrathecally administered antisense oligonucleotide targeting the mutated SOD1 gene that causes amyotrophic lateral sclerosis (ALS). Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more than 200 SOD1 mutations documented.[A259028,A259033] Tofersen was granted accelerated approval from the FDA...
Approved
Investigational
Matched Synonyms: … DNA, D((2'-O-(2-METHOXYETHYL))M5RC-SP-(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-SP-(2'-O-(2 ... (2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))R ... Antisense Oligonucleotide Inhibitor Of The Expression Of Superoxide Dismutase 1 Gene …
Matched Description: … [L46133] Tofersen demonstrated efficacy in reducing the concentration of SOD1 in CSF and of neurofilament ... [A259023] However, it could potentially be due to the short timeframe of tofersen treatment, and more ... [L46108] Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Approved
Matched Synonyms: … p-Menthan-3-ol
Matched Iupac: … 5-methyl-2-(propan-2-yl)cyclohexan-1-ol
Matched Mixtures name: … CVS Health Cold and Hot Roll-On ... CAMPHOR, EUCALYPTUS OIL and MENTHOL ... Lidocaine 4 Percent and Menthol 1 Percent Roll-On
Matched Products: … CVS Cold and Hot Roll-On ... QC Cool and Heat Roll-On ... Rite Aid Hot and Cold Roll On
Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-cov-2) Infection (COVID-19)).
Investigational
Matched Synonyms: … receptor and a mutant Fc fragment of human IGg1 and part of human IL1 receptor accessory protein ... Heterodimeric fusion protein that binds to IL-1 beta consisting of human extracellular domain of IL1 …
Matched Description: … Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of ... a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe …
Lactulose is a synthetic disaccharide derivative of lactose that is most commonly used as a laxative agent despite also being formally indicated to serve as an adjunct therapy in treating portal-systemic encephalopathy (PSE).[FDA Label,L6199,L6202] Despite being first synthesized in 1929 , investigations regarding its possible use as a laxative for...
Approved
Matched Synonyms: … 4-O-beta-D-Galactopyranosyl-D-fructose ... 4-O-beta-D-Galactopyranosyl-D-fructofuranose …
Matched Iupac: … (2S,3R,4S,5R,6R)-2-{[(2R,3S,4S,5R)-4,5-dihydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]oxy}-6-(hydroxymethyl …
Matched Description: … List of Essential Medicines as one of the most effective and safe medicines employed in a health system ... for treating constipation and its efficacy in managing PSE may never be formally confirmed or refuted ... a readily available generic and brand-name non-prescription medication listed on the World Health Organization's …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Orb-lactulose …
Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression. Reduction in...
Approved
Matched Iupac: … carbamoylamino)phenyl]-1-{[(1S)-1-{[(2S)-1-[(2S)-2-{[(1R)-1-carbamoylethyl]carbamoyl}pyrrolidin-1-yl]-1-oxo
Matched Description: … FDA approved on December 24, 2008. ... Degarelix is used for the treatment of advanced prostate cancer. ... derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Matched Products: … Firmagon 120mg Powder and Solvent for Solution for Injection ... Firmagon 80mg Powder and Solvent for Solution for Injection ... FIRMAGON Powder and Solvent for Solution for Injection 120 mg …
An obsolete fungicide used to control various pathogens on cereals and seed potatoes.
Experimental
Matched Synonyms: … o-Toluanilide ... o-Methylbenzanilide …
Matched Description: … An obsolete fungicide used to control various pathogens on cereals and seed potatoes. …
Approved
Investigational
Matched Products: … AFSTYLA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250IU/VIAL ... AFSTYLA 250IU powder and solvent for solution for injection ... AFSTYLA 500IU powder and solvent for solution for injection …
Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... the activity-related kringle-2 and serine protease domains of human tPA. ... delete certain portions of human tPA. …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Synonyms: … Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane …
Matched Description: … results in the decreased absorption and enhanced secretion of bile acids and lipids in the feces, patients ... of its pharmacological activity sometimes limits its usefulness. ... be good candidates for using the agent owing to its physical effects on the gut. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Aluminum zirconium octachlorohydrex gly is complex that consists of aluminum zirconium octachlorohydrate and glycine. It is an active antiperspirant agent , . It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores. The anhydrous form of the compound also has water-absorbing properties. Currently, the FDA allows...
Approved
Matched Description: … and glycine. ... It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores. ... Interestingly, this chemical has been studied in relation to its possible impact on the microbiome of
Matched Mixtures name: … Lactovit DEODORANT ROLL-ON MEN INVISIBLE ... Lactovit DEODORANT AND ANTIPERSPIRANT INVISIBLE ANTISTAIN …
Matched Products: … Degree Honeysuckle and Tea Tree Oil Antiperspirant and Deodorant ... Old Spice Sea Antiperspirant and Deodorant ... Old Spice GentleMan s Blend Mandarin and Musk …
Meradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different products as a UV filter. It is currently required to be named as meradimate in all FDA approved OTC products. Meradimate is approved by the FDA and Health Canada to be used as an...
Approved
Matched Synonyms: … Menthyl-O-aminobenzoate …
Matched Description: … Meradimate is approved by the FDA and Health Canada to be used as an ingredient in sunblocking products ... [T200] It is currently required to be named as meradimate in all FDA approved OTC products. ... Meradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different …
Matched Mixtures name: … Principal Secret Reclaim Sunscreen For Face and Body SPF 30 ... SPF 15 Spray-ON Sunscreen ... SPF 30+ Spray-ON Sunscreen …
A neurotransmitter. Acetylcholine in vertebrates is the major transmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system. It is generally not used as an administered drug because it is broken down very rapidly by cholinesterases,...
Approved
Investigational
Matched Synonyms: … O-Acetylcholine …
Matched Description: … sympathetic effector junctions, and at many sites in the central nervous system. ... transmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … Miochol E Acetylcholine Chloride Oph Soln …
A narcotic analgesic and antitussive. It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function. It is not marketed in the US but is approved for use in various countries around the world. In the US it is a schedule II drug (single-entity) and...
Experimental
Illicit
Matched Synonyms: … 3-O-Ethylmorphine …
Matched Iupac: … -7(18),8,10,15-tetraen-14-ol ... (1S,5R,13R,14S,17R)-10-ethoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca …
Matched Description: … It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function ... A narcotic analgesic and antitussive. ... In the US it is a schedule II drug (single-entity) and schedule III drug (in combination products). …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives ... Heterocyclic Compounds with 4 or More Rings ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Experimental
Matched Synonyms: … D-pyridoxyl-N,O-cycloserylamide-5-monophosphate …
Matched Name: … D-[3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-ylmethyl]-N,O-cycloserylamide …
Matched Iupac: … {[5-hydroxy-6-methyl-4-({[(4R)-3-oxo-1,2-oxazolidin-4-yl]amino}methyl)pyridin-3-yl]methoxy}phosphonic …
Experimental
Matched Synonyms: … 5'-O-(N-(L-Cysteinyl)-sulfamoyl)adenosine …
Matched Name: … 5'-O-(L-Cysteinylsulfamoyl)adenosine …
Matched Iupac: … 4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}sulfonyl)amino]-3-sulfanylpropan-1-one
Experimental
Matched Synonyms: … 6-O-β-D-galactopyranosyl-D-glucopyranose …
Matched Iupac: … (3R,4S,5S,6R)-6-({[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxane-2,3,4,5 …
Displaying drugs 101 - 125 of 708 in total