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Displaying drugs 1401 - 1425 of 3197 in total
Amcinonide
Amcinonide is a corticosteroid.
Approved
Matched Iupac: … 2-[(1'S,2'S,4'R,8'S,9'S,11'S,12'R,13'S)-12'-fluoro-11'-hydroxy-9',13'-dimethyl-16'-oxo-5',7'-dioxaspiro …
Lacosamide
Lacosamide is an antiepileptic drug used to treat seizures. As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium currents. Lacosamide exhibits a stereoselective mode of interaction with sodium channels. Lacosamide was first approved by the European Commission in August 2008 and was later...
Approved
Telotristat ethyl
Telotristat ethyl is a prodrug of telotristat that was approved by the FDA in March 2017 as Xermelo. It was previously referred to as telotristat etiprate, the hippurate salt form; however, the FDA recommends the use of the name of the neutral form rather than that of the salt.[A252937, A252942]...
Approved
Investigational
Ceftobiprole medocaril
Ceftobiprole medocaril is a prodrug of ceftobiprole, a fifth-generation semisynthetic cephalosporin antibacterial. Ceftobiprole is a broad-spectrum agent with demonstrated activity against both Gram-positive and Gram-negative bacteria, including antibiotic-resistant strains of Staphylcoccus aureus (methicillin-resistant Staphylococcus aureus; MRSA).
The EMA's Committee for Medicinal Products for Human Use (CHMP) adopted a negative opinion...
Approved
Experimental
Investigational
Matched Iupac: … (6R,7R)-7-[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(N-hydroxyimino)acetamido]-3-{[(3E,3'R)-1'-{[(5-methyl …
Dotatate gallium Ga-68
Dotatate gallium (Ga-68) is a somatostatin-2 receptor analog which is radiolabeled with gallium 68 as a positron-emitting radioisotope. Ga-68 dotatate has a high affinity for somatostatin-2 receptor and it is rapidly excreted from the nontarget sites which gives it an ideal candidate for imaging neuroendocrine tumors. Dotatate gallium (Ga-68) explotes...
Approved
Investigational
Matched Iupac: … (1R)-1-{[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}-7- …
Lutetium Lu 177 dotatate
A 177Lu-labeled somatostatin analog peptide, Lutetium Lu 177 dotatate belongs to an emerging form of treatments called Peptide Receptor Radionuclide Therapy (PRRT), which involves targeting tumours with molecules carrying radioactive particles that bind to specific receptors expressed by the tumour. Lutetium Lu 177 dotatate may also be referred to as...
Approved
Investigational
Matched Iupac: … (1R)-1-{[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}-7- …
Edotreotide gallium Ga-68
Edotreotide gallium Ga-68 is an 8 amino acid peptide bound to the chelator 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA). Edotreotide gallium Ga-68 is indicated for localizing somatostatin receptor positive neuroendocrine tumors by positron emission tomography. Dotatate gallium Ga-68 is used for a similar indication. Dotatate gallium Ga-68 has lower tumor uptake but this...
Approved
Matched Iupac: … {[(1R)-1-{[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-{[(2R,3R)-1,3-dihydroxybutan-2-yl]carbamoyl}-7- …
Vincristine
Vincristine is an antitumor vinca alkaloid isolated from Vinca Rosea. It is marketed under several brand names, many of which have different formulations such as Marqibo (liposomal injection) and Vincasar. Vincristine is indicated for the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. vincristine sulfate...
Approved
Investigational
Matched Iupac: … -yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7) …
Digitoxin
A cardiac glycoside sometimes used in place of digoxin. It has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting. (From Martindale, The Extra Pharmacopoeia, 30th ed, p665)
Approved
Investigational
Matched Iupac: … 4-[(1R,3aS,3bR,5aR,7S,9aS,9bS,11aR)-7-{[(2R,4S,5S,6R)-5-{[(2S,4S,5S,6R)-5-{[(2S,4S,5S,6R)-4,5-dihydroxy …
Digoxin
Digoxin is one of the oldest cardiovascular medications used today. It is a common agent used to manage atrial fibrillation and the symptoms of heart failure. Digoxin is classified as a cardiac glycoside and was initially approved by the FDA in 1954. This drug originates from the foxglove plant, also...
Approved
Matched Iupac: … 4-[(1R,3aS,3bR,5aR,7S,9aS,9bS,11R,11aS)-7-{[(2R,4S,5S,6R)-5-{[(2S,4S,5S,6R)-5-{[(2S,4S,5S,6R)-4,5-dihydroxy …
Adenosine
The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though it is rarely used in this indication, having largely been replaced by dipyridamole and [regadenson].[A229833,A229838] Adenosine...
Approved
Investigational
Matched Mixtures name: … Derma 7 Repaircream …
Ivermectin
Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and 10% 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)avermectin A1a (22,23-dihydroavermectin B1b). Ivermectin is mainly used in...
Approved
Investigational
Vet approved
Matched Iupac: … -methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-5,11',13',22'-tetramethyl-6-(propan-2-yl)-3',7' ... hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-5,11',13',22'-tetramethyl-3',7' …
Carbidopa
Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does not cross the blood-brain barrier. Due to its activity, carbidopa is always administered concomitantly with levodopa. An individual formulation containing solely carbidopa was generated to treat...
Approved
Matched Salts cas: … 38821-49-7 …
Matched Mixtures name: … DUODOPA 20 MG/ML + 5 MG/ML INTESTINAL JEL, 7 ADET …
Matched Mixtures name: … DUODOPA 20 MG/ML + 5 MG/ML INTESTINAL JEL, 7 ADET …
Polysorbate 60
Experimental
Matched International brands: … Tween 60 …
Matched Synonyms: … Polisorbato 60 ... Polysorbata 60 ... Polysorbate 60 …
Matched Name: … Polysorbate 60 …
Matched Synonyms: … Polisorbato 60 ... Polysorbata 60 ... Polysorbate 60 …
Matched Name: … Polysorbate 60 …
7-cyano-7-deazaguanine
Experimental
Matched Synonyms: … 7-CN-7-deazaG ... 7-Cyano-7-carbaguanine …
Matched Name: … 7-cyano-7-deazaguanine …
Matched Name: … 7-cyano-7-deazaguanine …
Cobalt Co-60
Cobalt Co-60 is under investigation in clinical trial NCT02891083 (Adjuvant Therapies or Surgery Alone for High Risk pN0 Esophageal Cancer).
Investigational
Matched Name: … Cobalt Co-60 …
Matched Description: … Cobalt Co-60 is under investigation in clinical trial NCT02891083 (Adjuvant Therapies or Surgery Alone …
Matched Description: … Cobalt Co-60 is under investigation in clinical trial NCT02891083 (Adjuvant Therapies or Surgery Alone …
Interleukin-7
Interleukin 7 has been used in trials studying the treatment of Metastatic Breast Cancer.
Investigational
Matched Synonyms: … IL-7 ... r-hIL-7 ... Interleukin 7 glycosylated …
Matched Name: … Interleukin-7 …
Matched Description: … Interleukin 7 has been used in trials studying the treatment of Metastatic Breast Cancer. …
Matched Name: … Interleukin-7 …
Matched Description: … Interleukin 7 has been used in trials studying the treatment of Metastatic Breast Cancer. …
Menaquinone 7
Menaquinone 7 is under investigation in clinical trial NCT00402974 (The Effect of Vitamin K Supplementation on Osteocalcin Carboxylation in Healthy Children).
Investigational
Matched Synonyms: … Menaquinone-7 …
Matched Name: … Menaquinone 7 …
Matched Description: … Menaquinone 7 is under investigation in clinical trial NCT00402974 (The Effect of Vitamin K Supplementation …
Matched Name: … Menaquinone 7 …
Matched Description: … Menaquinone 7 is under investigation in clinical trial NCT00402974 (The Effect of Vitamin K Supplementation …
Allovectin-7
Allovectin-7 or allovectin-7(r) is a lipid complex that contains the DNA sequences encoding HLA-B7 and beta-2 microglobulin. It was discontinued after it failed to improve the objective response rate or overall survival versus first-line chemotherapy in malignant melanoma.
Investigational
Matched Synonyms: … Allovectin-7(r) …
Matched Name: … Allovectin-7 …
Matched Description: … Allovectin-7 or allovectin-7(r) is a lipid complex that contains the DNA sequences encoding HLA-B7 and …
Matched Name: … Allovectin-7 …
Matched Description: … Allovectin-7 or allovectin-7(r) is a lipid complex that contains the DNA sequences encoding HLA-B7 and …
(2S)-7-hydroxyflavanone
Experimental
Matched Synonyms: … (-)-7-Hydroxyflavanone …
Matched Name: … (2S)-7-hydroxyflavanone …
Matched Iupac: … (2S)-7-hydroxy-2-phenyl-3,4-dihydro-2H-1-benzopyran-4-one …
Matched Name: … (2S)-7-hydroxyflavanone …
Matched Iupac: … (2S)-7-hydroxy-2-phenyl-3,4-dihydro-2H-1-benzopyran-4-one …
Angiotensin 1-7
TXA127 has been investigated for the treatment of Miscellaneous Peripheral Blood Cell Abnormalities.
Investigational
Matched Synonyms: … Angiotensin (1-7) ... Angiotensin I (1-7) ... Angiotensin II (1-7) heptapeptide …
Matched Name: … Angiotensin 1-7 …
Matched Name: … Angiotensin 1-7 …
7-Aminodesacetoxycephalosporanic acid
Experimental
Matched Synonyms: … 7-ADCA ... 3-methyl-7-amino-Δ3-cephem-4-carboxylic acid ... 3-methyl-7-aminoceph-3-em-4-carboxylic acid …
Matched Name: … 7-Aminodesacetoxycephalosporanic acid …
Matched Iupac: … (6R,7R)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Name: … 7-Aminodesacetoxycephalosporanic acid …
Matched Iupac: … (6R,7R)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
7-methyl-GpppA
Experimental
Matched Synonyms: … P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE …
Matched Name: … 7-methyl-GpppA …
Matched Iupac: … hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxyoxolan-2-yl]-7- …
Matched Name: … 7-methyl-GpppA …
Matched Iupac: … hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxyoxolan-2-yl]-7- …
7-Aza-L-tryptophan
Experimental
Matched Synonyms: … L-7-azatryptophan …
Matched Name: … 7-Aza-L-tryptophan …
Matched Name: … 7-Aza-L-tryptophan …
Displaying drugs 1401 - 1425 of 3197 in total