Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Displaying drugs 1401 - 1425 of 1446 in total

AOC 1001

AOC 1001 is an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 (TfR1) targeting, effector function null, humanized IgG1 antibody (AV01mAb) conjugated to one small interfering RNA (siRNA).
Investigational
Matched Synonyms: … an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 (TfR1) targeting …
Matched Description: … AOC 1001 is an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 …

AVR-RD-05

AVR-RD-05 is a gene therapy comprising genetically modified autologous stem cells transduced ex vivo with a lentiviral vector encoding the human iduronate-2-sulfatase (IDS) enzyme. It is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII).
Investigational
Matched Synonyms: … mediated, genetically modified autologous cell therapy intended for the stable provision of functional human …
Matched Description: … genetically modified autologous stem cells transduced _ex vivo_ with a lentiviral vector encoding the human …

Human papillomavirus type 18 L1 capsid protein residues 2-472 antigen

Approved
Investigational
Matched Name: … Human papillomavirus type 18 L1 capsid protein residues 2-472 antigen …

Ex vivo expanded autologous human corneal epithelial cells containing stem cells

Holoclar (ex vivo expanded autologous human corneal epithelial cells containing stem cells) is a stem cell therapy used to treat limbal stem cell deficiencies.
Investigational
Matched Name: … Ex vivo expanded autologous human corneal epithelial cells containing stem cells …
Matched Description: … Holoclar (_ex vivo_ expanded autologous human corneal epithelial cells containing stem cells) is a stem …

Allopurinol

Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints . This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals . Allopurinol is a xanthine oxidase enzyme inhibitor that...
Approved
Matched Description: … This disease has been well-documented in historical medical records and appears in the biographies of ... It was initially approved by the FDA in 1966 [L5674] and is now formulated by several manufacturers [ ... enzyme inhibitor that is considered to be one of the most effective drugs used to decrease urate levels and …
Matched Salts name: … Allopurinol sodium …
Matched Products: … Allopurinol sodium …

Efavaleukin alfa

Efavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin G Fc domain by way of a G4S linker. It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With Steroid Refractory Chronic Graft Versus Host Disease).
Investigational
Matched Synonyms: … fragment) fusion protein with peptide (synthetic linker) fusion protein with interleukin 2 (synthetic human …
Matched Description: … It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With …

scAAV9.U7.ACCA

scAAV9.U7.ACCA is a non-replicating recombinant adeno-associated virus vector containing 4 antisense sequences designed to target exon 2 in the human DMD gene under the control of U7 small nuclear non-coding RNA. Developed by Nationwide Children’s Hospital, it is being investigated for the treatment of Duchenne muscular dystrophy.
Investigational
Matched Synonyms: … recombinant adeno-associated virus vector containing 4 antisense sequences designed to target exon 2 in the human …
Matched Description: … recombinant adeno-associated virus vector containing 4 antisense sequences designed to target exon 2 in the human …

Rubella virus vaccine

Rubella virus vaccine is a live attenuated virus vaccine for active immunization against rubella (German measles) that is subcutaneously administered. It is prepared from RA 27/3 strain of live attenuated rubella virus. Rubella is a common childhood disease, caused by rubella virus (togavirus).
Approved
Investigational
Matched Synonyms: … Rubivirus rubella virus Wistar RA 27/3 whole …
Matched Mixtures name: … MEASLES AND RUBELLA VIRUS VACCINE LIVE ... SII Measles and Rubella Virus Vaccine live.Attenuated(Freeze-Dried) 1 dose ... SII Measles and Rubella Virus Vaccine live.Attenuated(Freeze-Dried) 10 doses …
Matched Categories: … measles, combinations with mumps and rubella, live attenuated ... measles, combinations with mumps, rubella and varicella, live attenuated …

2-(acetylamino)-2-deoxy-4-O-sulfo-alpha-D-galactopyranose

Experimental
Matched Name: … 2-(acetylamino)-2-deoxy-4-O-sulfo-alpha-D-galactopyranose …

Technetium Tc-99m red blood cells

Technetium Tc-99m red blood cells is a radiopharmaceutical diagnostic agent that is intravenously administered to be used in blood pool imaging, including cardiac first pass and gated equilibrium imaging and for detection of sites of gastrointestinal bleeding. It is clinically useful in early detection and localization of bleeding sites, and...
Approved
Matched Synonyms: … Technetium Tc-99m red blood cell human …
Matched Description: … It is clinically useful in early detection and localization of bleeding sites, and preoperative diagnosis ... gated equilibrium imaging and for detection of sites of gastrointestinal bleeding. ... agent that is intravenously administered to be used in blood pool imaging, including cardiac first pass and …

Giroctocogene fitelparvovec

Giroctocogene fitelparvovec is under investigation in clinical trial NCT04370054 (Study to Evaluate the Efficacy and Safety of PF-07055480 in Moderately Severe to Severe Hemophilia a Adults).
Investigational
Matched Synonyms: … Dna (recombinant adeno-associated virus 6 vector pf-07055480 human b-domain-deleted blood-coagulation …
Matched Description: … fitelparvovec is under investigation in clinical trial NCT04370054 (Study to Evaluate the Efficacy and …

AVID-200

AVID-200 is an Anti-transforming growth factor beta (TGF-β) trap fusion protein.
Investigational
Matched Synonyms: … Tgf-.beta. ligand trap comprised of tgf-.beta. receptor ectodomains fused to a human fc domain (avid- …

Porgaviximab

Investigational
Matched Synonyms: … with human-mus musculus monoclonal c2g4 .kappa. ... Immunoglobulin g1, anti-(ebolavirus glycoprotein) (human-mus musculus monoclonal c2g4 heavy chain), disulfide …

Schisandra chinensis fruit

Schisandra chinensis fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Five-flavoured Seed …

Leucovorin

Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin) is the 5-formyl derivative of tetrahydrofolic acid, a necessary co-factor in the body. Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the...
Approved
Matched Description: … Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary ... activity, the two commercially available forms have been shown to be pharmacokinetically identical and ... As folate analogs, leucovorin and levoleucovorin are both used to counteract the toxic effects of folic …
Matched Salts name: … Leucovorin sodium …
Matched Categories: … Enzymes and Coenzymes ... Folic Acid and Derivatives ... sodium folinate …
Matched Products: … CALCIUMFOLINAT LIQUID 1000 …

Prademagene zamikeracel

Investigational
Matched Synonyms: … Ex-vivo-expanded autologous keratinocytes transduced with retroviral vector containing the human COL7A1 …

Dynorphin

Dynorphin is under investigation in clinical trial NCT00000244 (Effects of Dynorphin 1-13 on Heroin Addiction - 1).
Investigational
Matched Synonyms: … Dynorphin a (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Firolimogene autotemcel

Investigational
Matched Synonyms: … ) PATIENTS, TRANSDUCED EX VIVO WITH A SELF-INACTIVATING LENTIVIRAL VECTOR, ENCODING CODON-OPTIMIZED HUMAN …

Alteplase

Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent. It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. In the absence of fibrin, the alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and fibrin.[A252330,L43125] Alteplase...
Approved
Investigational
Matched Synonyms: … Plasminogen activator (human tissue-type protein moiety) …
Matched Description: … alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and ... alteplase to manage AMI has decreased thanks to the availability of safer treatments such as angioplasty and ... thrombolytic agents derived from tissue plasminogen activator, such as [desmoteplase], [tenecteplase] and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs …

Vasoactive intestinal peptide

Investigational
Matched Synonyms: … Vasoactive intestinal peptide (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Fluoxetine

Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI). It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies.
Approved
Vet approved
Matched Description: … [A181673] It gained FDA approval in 1987 and although it was initially intended for the treatment of …
Matched Mixtures name: … Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine …
Matched Categories: … fluoxetine and psycholeptics ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … ANDEP ... PMS-fluoxetine Liquid - 20mg/5ml …

Equecabtagene autoleucel

Investigational
Matched Synonyms: … self-inactivating, non-replicating lentiviral vector encoding a chimeric antigen receptor (CAR) targeting human …

Bromhexine

Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing and reducing cough. It was introduced into the market in 1963, and is widely available as...
Approved
Matched Description: … and reducing cough. ... It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing ... It was introduced into the market in 1963, and is widely available as an over-the-counter drug in many …
Matched Mixtures name: … DURO-TUSS Expectorant Cough Liquid ... DURO-TUSS EXPECTORANT COUGH LIQUID …
Matched Categories: … Cough and Cold Preparations …
Matched Products: … DURO-TUSS CHESTY COUGH LIQUID …

Anvatabart opadotin

Investigational
Matched Synonyms: … HER2) (human-Mus musculus monoclonal Amab788 γ1-chain), disulfide with human-Mus musculus monoclonal ... Immunoglobulin G1 [121-(4-acetylphenylalanine),de-450-lysine], anti-(human epidermal growth factor receptor …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Tetracosactide

Tetracosactide (also known as Cosyntropin) is a synthetic peptide that is identical to the 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone. ACTH (1-24), a segment similar in all species, contains the biological activity that stimulates production of corticosteroids in the adrenal cortex. Tetracosactide exhibits the same...
Approved
Matched Synonyms: … Adrenocorticotropic hormone fragment 1-24 human, rat …
Matched Description: … The complex results in a product whose absorption in man is effected over a longer period of time as …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Anterior Pituitary Lobe Hormones and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Displaying drugs 1401 - 1425 of 1446 in total