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Displaying drugs 1426 - 1450 of 7028 in total
Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for the treatment of patients with inoperable CTEPH (chronic thromboembolic pulmonary hypertension), or persistent/recurrent PH (pulmonary hypertension)...
Approved
Matched Synonyms: … Methyl N-[4,6-Diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methyl-carbaminate …
Matched Iupac: … methyl N-(4,6-diamino-2-{1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl}pyrimidin-5-yl)-N-methylcarbamate …
Eluxadoline is a mixed mu-opioid receptor agonist, kappa-opioid receptor agonist, and a-delta opioid receptor antagonist indicated for use in diarrhea-predominant irritable bowel syndrome (IBS-D). The mu-, kappa-, and delta-opioid receptors mediate endogenous and exogenous opioid response in the central nervous system and peripherally in the gastrointestinal system. Agonism of peripheral...
Approved
Investigational
Matched Synonyms: … 5-({(4-carbamoyl-2,6-dimethyl-L-phenylalanyl)[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]amino}methyl)-2 …
Matched Iupac: … 5-{[(2S)-2-amino-3-(4-carbamoyl-2,6-dimethylphenyl)-N-[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]propanamido …
Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder. It has since received approval for a...
Approved
Matched Salts cas: … 136434-34-9
Matched Products: … Duloxetin Krka 90 mg magensaftresistente Hartkapseln ... Duloxetin neuraxpharm 90 mg magensaftresistente Hartkapseln …
Tizanidine is a fast-acting drug used for the management of muscle spasm, which may result from the effects of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury . It may also be caused by musculoskeletal injury . Regardless of the cause, muscle spasticity can be an...
Approved
Investigational
Matched Synonyms: … 5-Chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole …
Matched Iupac: … 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine …
Matched Products: … TIZAN 4 ... โทโนไลท์ 4 ... ทีดาร์ 4 มก. …
Approved
Withdrawn
Matched Iupac: … 3-amino-1-[1-(3,4-dichlorophenyl)ethyl]-4,5-dihydro-1H-pyrazol-5-one …
Tiopronin is a prescription thiol drug used primarily in the treatment of severe homozygous cystinuria. Patients with cystinuria excrete high levels of cystine in their urine and are at risk for kidney stone formation. Tiopronin is used as a second-line therapy to control the rate of cystine precipitation and excretion,...
Approved
Investigational
Extracted from the stem, leaves, and flowers of Mentha piperita L. plant, peppermint oil (Mentha piperita) is a popular essential oil used in aromatherapy for both external and internal use. Mentha piperita is a hybrid of spearmint (Mentha spicata) and water mint (Mentha aquatica) . Medicinal use of herbal ingredients...
Approved
Investigational
Cannabidiol, or CBD, is one of at least 85 active cannabinoids identified within the Cannabis plant. It is a major phytocannabinoid, accounting for up to 40% of the Cannabis plant's extract, that binds to a wide variety of physiological targets of the endocannabinoid system within the body. Although the exact...
Approved
Investigational
Matched Synonyms: … (1'R,2'R)-5'-methyl-4-pentyl-2'-(prop-1-en-2-yl)-1',2',3',4'-tetrahydrobiphenyl-2,6-diol ... (−)-trans-2-p-mentha-1,8-dien-3-yl-5-pentylresorcinol …
Matched Iupac: … 2-[(1R,6R)-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-en-1-yl]-5-pentylbenzene-1,3-diol …
Matched Description: … the well-known activity on CB1 and CB2 receptors, there is further evidence that CBD also activates 5- ... The primary psychoactive component of Cannabis, delta 9-tetrahydrocannabinol (Δ9-THC), demonstrates its …
Matched Categories: … Serotonin 5-HT1 Receptor Agonists ... Serotonin 5-HT2 Receptor Agonists …
Matched Products: … leafPro CBDmed Oil T-FS QD 5% ... leafPro CBDmed Oil FS QP 5% …
A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Approved
Investigational
Matched Mixtures name: … HydroGold 9 ... CELLSTORY Plus Cellplant Meso-Care Program (4 week) ... Pranicura 5
Matched Products: … Neogen Code 9 Black Volume Cream ... Dr.NUELL Propolis Real 90 Ampoule ... essenHERB Tea Tree 90 Calming Toner …
A potent and specific HIV protease inhibitor that appears to have good oral bioavailability. [PubChem]
Approved
Matched Synonyms: … )carbonyl)-4-(3-pyridinylmethyl)-1-piperazinyl)-2-(phenylmethyl)-D-erythro-pentonamide ... (1(1S,2R),5(S))-2,3,5-Trideoxy-N-(2,3-dihydro-2-hydroxy-1H-inden-1-yl)-5-(2-(((1,1-dimethylethyl)amino …
Matched Iupac: … (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-4-{[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamoyl}butyl]-N-tert-butyl ... -4-[(pyridin-3-yl)methyl]piperazine-2-carboxamide …
A non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of action to indomethacin.
Approved
Matched Synonyms: … 1-Methyl-5-(4-methylbenzoyl)-pyrrole-2-acetic acid ... 1-Methyl-5-p-toluoylpyrrole-2-acetic acid ... 5-(p-Toluoyl)-1-methylpyrrole-2-acetic acid …
Matched Iupac: … 2-[1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetic acid …
Levonorgestrel (LNG) is a synthetic progestogen similar to Progesterone used in contraception and hormone therapy.[A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD. Some of these devices...
Approved
Investigational
Matched Synonyms: … 13-Ethyl-17-alpha-ethynylgon-4-en-17-beta-ol-3-one ... 17alpha-Ethynyl-17-hydroxy-18-methylestr-4-en-3-one ... 13-Ethyl-17-alpha-ethynyl-17-beta-hydroxy-4-gonen-3-one …
Vinflunine is a third-generation member of the vinca alkaloid family with anti-tumour actions. It was first described in 1998 at the Pierre Fabre research center in France. Like other vinca agents, vinflunine is an anti-mitotic agent that induces a cell cycle arrest at the G2/M phase and promotes cell death...
Approved
Investigational
Matched Synonyms: … 4'-deoxy-20',20'-difluoro-5'-norvincaleukoblastine ... 20',20'-difluoro-3',4'-dihydrovinorelbine ... 4'-deoxy-20',20'-difluoro-8'-norvincaleukoblastine …
Matched Iupac: … methyl (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-4-[(1R,12S,14S,16R)-16-(1,1-difluoroethyl)-12-(methoxycarbonyl ... 1,10-diazatetracyclo[12.3.1.0^{3,11}.0^{4,9}]octadeca-3(11),4,6,8-tetraen-12-yl]-12-ethyl-10-hydroxy-5- …
Matched Description: … While these patients have a median survival of approximately 4 months and a poor prognosis [L1396], there …
Matched Salts cas: … 194468-36-5
Dexmethylphenidate is the dextrorotary form of methylphenidate introduced in 2002 . It is a norepinephrine-dopamine reuptake inhibitor (NDRI) and thus a psychostimulant . It is used for treatment of Attention Deficit Hyperactivity Disorder (ADHD)[Label,A177181]. The d-isomer is thought to have greater effect with fewer side effects than the l-isomer or...
Approved
Investigational
Omega-3 fatty acids are polyunsaturated fatty acids (PUFAs) with a double bond at the third carbon atom from the end of the carbon chain. The three types of omega-3 fatty acids involved in human physiology are α-linolenic acid (ALA) (found in plant oils), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA)...
Approved
Nutraceutical
Matched Mixtures name: … aspen nutrition Omega 3-6-9
Ulipristal is a selective progesterone receptor modulator used for the purposes of emergency contraception (Ella) and for the treatment of uterine fibroids (Fibristal). It is a derivative of 19-norprogesterone and has both antagonistic and partial agonist activity at the progesterone receptor. It also binds to glucocorticoid receptor, however compared to...
Approved
Matched Iupac: … 2,7}.0^{11,15}]heptadeca-1,6-dien-5-one ... (10S,11S,14R,15S,17R)-14-acetyl-17-[4-(dimethylamino)phenyl]-14-hydroxy-15-methyltetracyclo[8.7.0.0^{ …
Matched Salts cas: … 126784-99-4
Matched Products: … เอสมายาชนิดเม็ด 5 มก. ... ESMYA® 5 MG COMPRIMIDOS …
Nitrogen mustard derivative of uracil. It is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal and bone marrow damage.
Approved
Matched Synonyms: … 5-aminouracil mustard ... 5-(di-2-chloroethyl)aminouracil ... 5-[di(β-chloroethyl)amino]uracil …
Matched Iupac: … 5-[bis(2-chloroethyl)amino]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Magnesium aluminum silicate is a naturally occurring mineral obtained from silicate ores of the montmorillonite group . It is refined to a powder for use in cosmetic and pharmaceutical applications as an absorbent, anticaking agent, opacifying agent, viscosity-increasing agent, suspending agent, tablet and capsule disintegrant, and tablet binder. It also...
Approved
Artenimol is an artemisinin derivative and antimalarial agent used in the treatment of uncomplicated Plasmodium falciparum infections [FDA Label]. It was first authorized for market by the European Medicines Agency in October 2011 in combination with DB13941 as the product Eurartesim. Artemisinin combination therapy is highly effective against malaria and...
Approved
Experimental
Investigational
Calcium supplements such as calcium gluceptate are taken by individuals who are unable to get enough calcium in their regular diet or who have a need for more calcium. They are used to prevent or treat several conditions that may cause hypocalcemia (not enough calcium in the blood). The body...
Approved
Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction. In comparison with other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both sildenafil and vardenafil but less selectivity than tadalafil, suggesting a relatively lower risk of visual disturbances associated with...
Approved
Matched Synonyms: … (S)-4-(3-Chloro-4-methoxybenzylamino)-2-(2-hydroxymethylpyrrolidin-1-yl)-N-pyrimidin-2-ylmethyl-5-pyrimidinecarboxamide …
Matched Iupac: … -yl)methyl]pyrimidine-5-carboxamide ... 4-{[(3-chloro-4-methoxyphenyl)methyl]amino}-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-[(pyrimidin-2 …
Matched Description: … Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction. …
Matched Categories: … Phosphodiesterase 5 Inhibitors …
Matched Products: … STENDRA 100 MG TABLET, 4 ADET ... STENDRA 200 MG TABLET, 4 ADET ... STENDRA 50 MG TABLET, 4 ADET …
Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against both compared to third-generation antibiotics.[A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused by multi-resistant microorganisms such as Pseudomonas aeruginosa, and is also indicated...
Approved
Investigational
Matched Synonyms: … -1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate ... (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(1-methylpyrrolidinium …
Matched Iupac: … 1-{[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-carboxylato-8-oxo-5-thia …
Matched Salts cas: … 123171-59-5
Vitamin D ultimately comprises a group of lipid-soluble secosteroids responsible for a variety of biological effects, some of which include increasing the intestinal absorption of calcium, magnesium, and phosphate. With reference to human use, there are 2 main forms of vitamin D - vitamin D3 (cholecalciferol) and vitamin D2 (ergocalciferol)....
Approved
Nutraceutical
Vet approved
Matched Mixtures name: … CitraNatal 90 DHA ... CitraNatal 90 DHA ... MENAPHASE FORMULA FILM TABLET, 90 ADET …
Ezetimibe is a lipid-lowering compound that inhibits intestinal cholesterol and phytosterol absorption. The discovery and research of this drug began in the early 1990s, after the intravenous administration of radiolabelled ezetimibe in rats revealed that it was being localized within enterocytes of the intestinal villi - this prompted studies investigating...
Approved
Matched Iupac: … (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2- …
Matched Mixtures name: … EZATOR 10/10 MG FILM KAPLI TABLET, 90 ADET ... EZATOR 10/20 MG FILM KAPLI TABLET, 90 ADET ... EZATOR 10/40 MG FILM KAPLI TABLET, 90 ADET …
Bismuth subsalicylate is an antacid and anti-diarrheal agent. Exhibiting antibacterial and gastroprotective properties, bismuth subsalicylate is an insoluble salt of salicylic acid linked to trivalent bismuth cation. Each molecule of bismuth subsalicylate contains 58% bismuth and 42% salicylate by weight. Bismuth subsalicylate has been around for over 100 years: it...
Approved
Vet approved
Matched Synonyms: … 2-Hydroxy-benzo[1,3,2]dioxabismin-4-one …
Matched Iupac: … 2-hydroxy-2H,4H-benzo[d]1,3-dioxa-2-bismacyclohexan-4-one …
Matched Products: … Up and Up 5-symptom Digestive Relief …
Displaying drugs 1426 - 1450 of 7028 in total