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Displaying drugs 126 - 150 of 2378 in total
Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... the activity-related kringle-2 and serine protease domains of human tPA. ... Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs …
Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Synonyms: … Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane …
Matched Description: … enhanced secretion of bile acids and lipids in the feces, patients who take complicated medication regimens ... Bile acid sequestrants like colestipol have been in use since the 1970s. ... [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated …
Matched Categories: … Bile Acid Sequestrants ... Non-statin Hypolipidemic Agents Indicated for Hyperlipidemia ... Bile-acid Binding Activity …
Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Matched Synonyms: … Alendronic acid ... Acido Alendronico ... Acide Alendronique …
Matched Name: … Alendronic acid
Matched Iupac: … (4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid
Matched Description: … osteoperosis and Paget's disease[FDA Label][A959,A203111]. ... Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of …
Matched Mixtures name: … ACIDO ALENDRONICO E COLECALCIFEROLO EG ... ACIDO ALENDRONICO E COLECALCIFEROLO EG ... ACIDO ALENDRONICO E COLECALCIFEROLO EG …
Matched Categories: … alendronic acid and colecalciferol ... alendronic acid and alfacalcidol, sequential ... alendronic acid, calcium and colecalciferol, sequential ... Drugs Affecting Bone Structure and Mineralization ... alendronic acid
Matched Products: … ACIDO ALENDRONICO FIDIA ... ALENDRONAT ACIS 70MG ... ACIDO ALENDRONICO FG …
Human chorionic gonadotropin (HCG), a polypeptide hormone produced by the human placenta. Endogenously produced HCG interacts with the LHCG receptor of the ovary and promotes the maintenance of the corpus luteum during the beginning of pregnancy. This allows the corpus luteum to continuously secrete the hormone progesterone during the first...
Approved
Vet approved
Matched Description: … HCG is composed of an alpha and a beta sub-unit. ... human thyroid-stimulating hormone (TSH), while the beta sub­ units of these hormones differ in amino acid ... Endogenously produced HCG interacts with the LHCG receptor of the ovary and promotes the maintenance …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Gonadotropins and Antigonadotropins ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Powder and Solvent for Solution for Injection ... Choriomon 5000 IU powder and solvent for solution for injection ... PUBERGEN 7500IU (Chorionic Gonadotropin for Injection USP 7500IU/Vial and Sodium Chloride Injection USP …
Carbamide peroxide, also known as urea-hydrogen peroxide, is a water-soluble, white crystalline solid compound consisting of hydrogen peroxide and urea. As it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products. Some adverse effects of carbamide peroxide as a dental bleaching agent include...
Approved
Matched Description: … It is available in OTC otic drugs as non-water, non-oil-based solutions used to soften, loosen and remove ... /or gingival irritation led by unstable and reactive H+ free radicals and low pH from prolonged use. ... As it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products …
Matched Products: … Ear Wax Removal Drops Up and Up ... Foster and Thrive Earwax Removal Drops ... CareOne Earwax Removal Kit, Earwax and Bulb …
The human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma glycoprotein involved in hemostasis. It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood vessel injury and stabilizing procoagulant factor VIII (FVIII). Exogenous sources of vWF...
Approved
Investigational
Matched Description: … and hemophilia A. ... vessel injury and stabilizing procoagulant factor VIII (FVIII). ... It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... von Willebrand factor and coagulation factor VIII in combination …
Matched Products: … IMMUNATE 50 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... IMMUNATE 100 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and induces tumour cell death. Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to...
Approved
Matched Description: … and induces tumour cell death. ... [A260621] As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules ... [A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17 …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … JEVTANA 60mg CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION ... JEVTANA (CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION) ... Cabazred 60mg/1.5ml Concentrate And Solvent For Solution For Infusion …
Chenopodium album pollen is the pollen of the Chenopodium album plant. Chenopodium album pollen is mainly used in allergenic testing.
Approved
Matched Categories: … Non-Standardized Pollen Allergenic Extract …
Matched Products: … Pollens - Weeds and Garden Plants, Lamb Quarters Chenopodium album ... Pollens - Weeds and Garden Plants, Lambs Quarters Chenopodium album …
A depressor amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
Approved
Investigational
Matched Description: … a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and
Matched Mixtures name: … Histamine DHCl 0.10 Percent and Menthol 2 Percent …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Hand and Wrist Pain Cream ... Australian Dream Hand and Wrist Pain ... MINTED LEAF Odorless Histamine DHCl Pain Relief and Hemp Extract …
Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential component of the coagulation cascade. Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) and purified from extraneous plasma-derived...
Approved
Matched Description: … The final purified concentrate contains albumin as a stabilizer.[L1053]. ... Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant ... as a result, leads to easy bruising and bleeding. …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250 IU ... Octanate 500IU Powder and Solvent for Solution for Injection …
Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-cov-2) Infection (COVID-19)).
Investigational
Matched Synonyms: … a mutant Fc fragment of human IGg1 and part of human IL1 receptor accessory protein ... Heterodimeric fusion protein that binds to IL-1 beta consisting of human extracellular domain of IL1 receptor and
Matched Description: … Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of ... a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe …
A guanido-neuraminic acid that is used to inhibit neuraminidase.
Approved
Investigational
Matched Synonyms: … 5-acetamido-2,6-anhydro-3,4,5-trideoxy-4-guanidino-D-glycero-D-galacto-non-2-enonic acid ... 5-(acetylamino)-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-D-glycero-D-galacto-non-2-enonic acid ... 4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid
Matched Iupac: … diaminomethylidene)amino]-3-acetamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
Matched Description: … A guanido-neuraminic acid that is used to inhibit neuraminidase. …
Matched Categories: … Acids, Acyclic ... Sugar Acids ... Sialic Acids ... Hydroxy Acids ... Carboxylic Acids
DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo. It is under investigation for the treatment of ovarian cancer.
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo …
Matched Description: … DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and
CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic SP-B analogue.
Investigational
Matched Synonyms: … Synthetic surfactant comprised of DPPC, POPG Na, synthetic SP-C analogue and synthetic SP-B analogue …
Matched Description: … dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Phosphatidic Acids
Anti-inhibitor coagulant complex, also known as FEIBA (factor eight inhibitor bypassing activity), contains several proteins involved in the prothrombinase complex. It is used to control bleeding in hemophilia A and B patients with inhibitors.
Approved
Investigational
Matched Description: … It is used to control bleeding in hemophilia A and B patients with inhibitors. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … FEIBA (Factor VIII Inhibitor Bypassing Activity) 25U/ml Powder and solvent for solution for infusion ... FEIBA (Factor VIII Inhibitor Bypassing Activity) 50U/ml Powder and solvent for solution for infusion …
Isotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne.[Label] It was most widely marketed under the brand name Accutane, which has since been discontinued. Isotretinoin is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the...
Approved
Matched Synonyms: … 13-cis-retinoic acid ... (7E,9E,11E,13Z)-retinoic acid ... Neovitamin A acid
Matched Iupac: … (2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
Matched Description: … [L6574] Isotretinoin is associated with major risks in pregnancy and is therefore only available under ... Isotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne. …
Matched Categories: … Skin and Mucous Membrane Agents …
Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for...
Approved
Investigational
Matched Name: … Indocyanine green acid form …
Matched Products: … Spy Agent Green Kit for Advanced Imaging Modality (aim) and Pinpoint ... Spy Agent Green Lymphatics Kit for Advanced Imaging Modality (aim) and Pinpoint …
Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. The halophenol is shown to be most effective against Gram positive bacteria where it disrupts the cell wall due to its phenolic...
Approved
Matched Description: … disinfection and surgical instruments. ... It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. ... Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin …
Matched Categories: … Phenol and Derivatives ... Antiseptics and Disinfectants …
Matched Products: … Gold and Sudsy ... Clorox Citrus and Sage Dish ... Up (and) Up Green Apple Scent …
Experimental
Matched Synonyms: … Glycerophosphoric acid ... Phosphoric acid mono-((R)-2,3-dihydroxy-propyl) ester ... Glycerol-3-phosphate …
Matched Name: … sn-glycerol 3-phosphate …
Matched Iupac: … [(2R)-2,3-dihydroxypropoxy]phosphonic acid
Approved
Experimental
Matched Mixtures name: … Bengay Ultra Strength Non-greasy ... Muscle Rub Non Greasy Pain Relieving ... Bengay Ultra Strength Non Greasy Pain Relieving …
Matched Products: … Soothe and Move Pain Relief Cream ... Arthritis and Joint Pain Relief Thayers ... Weeks and Leo Medicated Vaporizing Steam …
VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking the CD33 protein.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking …
Matched Description: … VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy …
Colloidal oatmeal is produced by grinding fine granules of oatmeal and boiling it to extract the colloidal material. It contains high concentrations of starches and beta-glucan that exhibits water-absorbing properties. Phenols are also contained in colloidal oatmeal, which possess antioxidant and anti-inflammatory activities, as well as UV-absorbing activity. Colloidal oatmeal...
Approved
Nutraceutical
Matched Description: … Colloidal oatmeal is produced by grinding fine granules of oatmeal and boiling it to extract the colloidal ... It contains high concentrations of starches and beta-glucan that exhibits water-absorbing properties. ... skin irritation and itching due to rashes, eczema, poison ivy, oak, sumac, or insect bites. …
Matched Mixtures name: … Dermavive Shower and Bath Oil …
Matched Categories: … Non-Standardized Food Allergenic Extract ... Non-Standardized Plant Allergenic Extract …
Matched Products: … Bite and Sting Soother ... Skinfix Calm and Nourish Body ... Calming Itch and Irritation …
Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison...
Approved
Investigational
Matched Description: … This effect leads to inhibition of both basal and stimulated gastric acid secretion, irrespective of ... Esomeprazole exerts its stomach acid-suppressing effects by preventing the final step in gastric acid ... and bone fractures later in life. …
Matched Mixtures name: … Naproxen and esomeprazole magnesium ... Naproxen and esomeprazole magnesium ... Naproxen and Esomeprazole Magnesium …
Matched Categories: … Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acid Reducers ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism …
Matched Products: … Foster and Thrive Acid Reducer ... Acid Reducer ... Harris Teeter Acid Reducer …
ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK).
Investigational
Matched Synonyms: … humanized immunoglobulin gamma 1 (IgG1) agonistic monoclonal antibody (mAb) that specifically targets and
Matched Description: … ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK). …
Exenatide is a glucagon-like peptide-1 (GLP-1) analog . It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows gastric emptying to improve glycemic control . Exenatide was given FDA approval on April 28, 2005 . It is available as immediate- and extended-release formulations.[L42685,L42690] Bydureon, the brand...
Approved
Investigational
Matched Description: … gastric emptying to improve glycemic control[L42690]. ... It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows ... It is available as immediate- and extended-release formulations. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Fluids and Secretions ... Alimentary Tract and Metabolism ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … BYDUREON 2 mg powder and solvent for prolonged-release suspension for injection ... BYDUREON POWDER AND SOLVENT FOR PROLONGED-RELEASE SUSPENSION FOR INJECTION IN PRE-FILLED PEN 2MG …
Displaying drugs 126 - 150 of 2378 in total