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Displaying drugs 126 - 150 of 14540 in total

Cimetidine

A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Description: … It inhibits gastric acid secretion, as well as pepsin and gastrins output. …
Matched Categories: … Medications that reduce magnesium levels ... Alimentary Tract and Metabolism ... Metabolic Side Effects of Drugs and Substances ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … Up and Up Acid Reducer …

Metolazone

A quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful in chronic renal failure. It also tends to lower blood pressure and increase potassium loss.
Approved
Matched Description: … It also tends to lower blood pressure and increase potassium loss. …
Matched Categories: … Medications that reduce magnesium levels ... Genito Urinary System and Sex Hormones ... metolazone and potassium-sparing agents ... Gynecological Antiinfectives and Antiseptics ... Low-Ceiling Diuretics and Potassium-Sparing Agents …

Meticillin

One of the penicillins which is resistant to penicillinase but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection.
Approved
Investigational

Human calcitonin

Calcitonin was first discovered in isolated parathyroid tissue as a substance with a serum-calcium-lowering effect. It is constituted as a 32-amino acid single chain polypeptide structure that gets secreted as a regulatory agent in calcium-phosphorus metabolism. It is used as an alternative for people developing antibodies against salmon calcitonin.
Approved
Investigational
Matched Categories: … Sex Hormones and Insulins ... Medications that increase serum magnesium …

Tacrolimus

Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis...
Approved
Investigational
Matched Iupac: … ,25S,27R)-1,14-dihydroxy-12-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy …
Matched Description: … drug whose main use is after organ transplant to reduce the activity of the patient's immune system and ... the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants, and ... This FKBP12-FK506 complex inhibits calcineurin which inhibits T-lymphocyte signal transduction and IL …
Matched Categories: … Medications that reduce magnesium levels ... Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents …

Pantothenic acid

Pantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin discovered by Roger J. Williams in 1919. For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats....
Approved
Nutraceutical
Vet approved
Matched Description: … Pantothenic acid is the amide between pantoic acid and β-alanine and commonly found as its alcohol analog ... metabolize proteins, carbohydrates, and fats. ... , the provitamin panthenol, and as calcium pantothenate. …
Matched Mixtures name: … C-apnto-B6 Vitamins W Magnesium Tab ... Multi Vitamin and Mineral vitamin ... Vitamin and Mineral Drink Mix …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Preparations for Treatment of Wounds and Ulcers …

Flurbiprofen

Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Description: … Flurbiprofen is structurally and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen. ... Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and ... formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Strepsils MaxPro Honey and Lemon lozenges 8.75mg …

Vitamin A

Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in...
Approved
Nutraceutical
Vet approved
Matched Description: … , the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune ... It is enriched in the liver, egg yolks, and the fat component of dairy products. ... Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina …
Matched Mixtures name: … Kidmag Vitamins W Magnesium Tab ... Vitamin A and D ... A and D Ointment …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …

Vernakalant

Vernakalant was developed by Cardiome Pharma as as an antiarrhythmic drug intended for rapid conversion of atrial fibrillation to sinus rhythm. It acts as an atypical class III antiarrhythmic drug that potentiates its effect in higher heart rates. Intravenous formulation was approved in Europe in September 2010 as Brinavess and...
Approved
Investigational
Matched Description: … Intravenous formulation was approved in Europe in September 2010 as Brinavess and in Canada in April …

Doxercalciferol

Doxercalciferol is a synthetic vitamin D2 analog that undergoes metabolic activation in vivo to form 1α,25-dihydroxyvitamin D2 (1α,25-(OH)2D2), a naturally occurring, biologically active form of vitamin D2. Doxercalciferol is indicated for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease on dialysis, as well as for the treatment...
Approved
Matched Description: … Doxercalciferol is marketed under the brand name Hectoral by Genzyme Corporation, and is manufactured …
Matched Categories: … Medications that increase serum magnesium ... Diet, Food, and Nutrition ... Vitamin D and Analogues ... Sex Hormones and Insulins …

Flavone

Approved
Experimental

Drostanolone propionate

Approved
Illicit
Matched Categories: … Testosterone and derivatives …

Pamidronic acid

Pamidronic acid is a second generation, nitrogen containing bisphosphonate similar to neridronic acid and alendronic acid. Pamidronic acid was first described in the literature in 1977. The second generation bisphosphonates are less common as third generation bisphosphonates, such as ibandronic acid, zoledronic acid, minodronic acid, and risedronic acid are becoming...
Approved
Matched Description: … Pamidronic acid is a second generation, nitrogen containing bisphosphonate similar to [neridronic acid] and ... third generation bisphosphonates, such as [ibandronic acid], [zoledronic acid], [minodronic acid], and …
Matched Categories: … Medications that reduce magnesium levels ... Drugs Affecting Bone Structure and Mineralization …

Sodium zirconium cyclosilicate

Sodium zirconium cyclosilicate is approved as the trade product Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a powder for oral suspension that acts as a highly selective potassium removing agent. It is administered orally and is odorless, tasteless, and stable at room temperature. Approval...
Approved
Investigational
Matched Description: … [L2933] It is administered orally and is odorless, tasteless, and stable at room temperature. ... Approval of the medication is supported by data from three double-blind, placebo-controlled trials and ... two open-label trials which showed that the onset of action was approximately 1.0 hour and the median …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …

Lynestrenol

Lynestrenol is a progestin and prodrug of norethisterone.
Approved
Investigational
Matched Description: … Lynestrenol is a progestin and prodrug of [norethisterone]. …
Matched Categories: … lynestrenol and estrogen ... lynestrenol and estrogen ... lynestrenol and ethinylestradiol ... lynestrenol and ethinylestradiol ... Genito Urinary System and Sex Hormones …

Ursodeoxycholic acid

Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool.[A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional medicine dates back more than a hundred years.[A256267,A256463] UDCA was first characterized...
Approved
Investigational
Matched Description: … [A256267,A256463] UDCA was first characterized in the bile of the Chinese black bear and is formed by ... [A256272] UDCA was first approved by the FDA in 1987 for dissolution of gallstones and for primary …
Matched Categories: … Bile Acids and Salts ... Bile and Liver Therapy ... Bile acids and derivatives ... Alimentary Tract and Metabolism ... Cholagogues and Choleretics …

Ascorbyl phosphate

Ascorbyl phosphate is a synthetic form of Vitamin C and is found in different salt forms such as magnesium ascorbyl phosphate and sodium ascorbyl phosphate. These salts are present in cosmetic products at concentrations ranging from 0.001 % to 3% . As vitamin C is susceptible to breakdown of compound...
Approved
Matched Description: … Ascorbyl phosphate is a synthetic form of Vitamin C and is found in different salt forms such as magnesium ... ascorbyl phosphate and sodium ascorbyl phosphate. ... phosphate, along with other Vitamin C derivatives, acts as an active and stable precursor of vitamin …
Matched Salts name: … Magnesium ascorbyl phosphate …
Matched Categories: … Vitamin C and analogues …

Desoxyribonuclease

Desoxyribonuclease is a crystalline enzyme that aids in the digestion of the thymus nucleic acid. The mechanism of action of the enzyme involves the splitting of thymus nucleic acid into fragments approaching the size of tetranucleotides without the release of free phosphoric acid. The enzyme's cofactor is reported to be...
Approved
Matched Description: … The enzyme's cofactor is reported to be magnesium (or manganese) ions, although the optimal concentration …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... fibrinolysin and desoxyribonuclease …

Dextropropoxyphene

Dextropropoxyphene is an opioid analgesic manufactured by Eli Lilly and Company. It is used in the symptomatic treatment of mild pain. It displays antitussive and local anaesthetic actions. Due to the risk of cardiac arrhythmias and overdose, possibly leading to death, dextropropoxyphene has been withdrawn from the market in Europe...
Approved
Illicit
Investigational
Withdrawn
Matched Description: … It displays antitussive and local anaesthetic actions. ... been withdrawn from the market in Europe and the United States. ... Dextropropoxyphene is an opioid analgesic manufactured by Eli Lilly and Company. …
Matched Mixtures name: … Propoxyphene and Acetaminophen ... Propoxyphene and Acetaminophen ... Propoxyphene and Acetaminophen …

Tazobactam

Tazobactam is an antibiotic of the beta-lactamase inhibitor class that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms. It is combined with Piperacillin and Ceftolozane for the treatment of a variety of bacterial infections. Piperacillin-tazobactam was initially approved by the FDA in 1994, and ceftolozane-tazobactam was approved...
Approved
Matched Description: … It is combined with [Piperacillin] and [Ceftolozane] for the treatment of a variety of bacterial infections ... ventilator-associated bacterial pneumonia, which are significant causes of morbidity and mortality in ... , ceftolozane-tazobactam was approved by the FDA for treating hospital-acquired bacterial pneumonia and …
Matched Mixtures name: … Piperacillin and Tazobactam ... Piperacillin and Tazobactam ... Piperacillin and Tazobactam …

Chlordiazepoxide

An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
Approved
Illicit
Investigational
Matched Description: … An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. …
Matched Mixtures name: … Chlordiazepoxide and Amitriptyline Hydrochloride ... Chlordiazepoxide and Amitriptyline HCl ... Chlordiazepoxide and Amitriptyline HCl …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepines and benzodiazepine derivatives ... Nucleic Acids, Nucleotides, and Nucleosides …

Oxycodone

Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone...
Approved
Illicit
Investigational
Matched Description: … [A178696] It is currently indicated as an immediate release product for moderate to severe pain and as …
Matched Mixtures name: … Oxycodone and Aspirin ... Oxycodone and Aspirin ... Oxycodone and Acetaminophen …
Matched Categories: … oxycodone and naloxone ... oxycodone and ibuprofen ... oxycodone and naltrexone ... oxycodone and paracetamol ... oxycodone and acetylsalicylic acid …

Clavulanic acid

Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with Amoxicillin or Ticarcillin to fight antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of susceptible bacterial infections. Clavulanic acid is derived from the organism Streptomyces clavuligerus. When it is combined with amoxicillin, clavulanic acid is...
Approved
Vet approved
Matched Mixtures name: … Amoxicillin and clavulanate potassium ... Amoxicillin and clavulanate potassium ... Amoxicillin and clavulanate potassium …

Misoprostol

Misoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages, prevent post partum hemorrhage, and also for first trimester abortions.[L7616,L7619,A181589,A181583,A181697] The stimulation of prostaglandin receptors in the stomach reduces gastric acid secretion, while stimulating these receptors in the uterus and cervix can increase the...
Approved
Matched Description: … cervix can increase the strength and frequency of contractions and decrease cervical tone. ... used to reduce the risk of NSAID related ulcers, manage miscarriages, prevent post partum hemorrhage, and ... receptors in the stomach reduces gastric acid secretion, while stimulating these receptors in the uterus and …
Matched Mixtures name: … Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol …
Matched Categories: … naproxen and misoprostol ... Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …

Zidovudine

A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator...
Approved
Matched Description: … It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves ... Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia …
Matched Mixtures name: … Lamivudine and Zidovudine ... Lamivudine and Zidovudine ... Lamivudine and Zidovudine …
Matched Categories: … Medications that reduce magnesium levels ... zidovudine and lamivudine ... zidovudine, lamivudine and abacavir ... zidovudine, lamivudine and nevirapine ... Nucleic Acids, Nucleotides, and Nucleosides …
Displaying drugs 126 - 150 of 14540 in total