Displaying drugs 1526 - 1550 of 7374 in total
Pasireotide
Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Approved
Matched Synonyms: … cyclo((4R)-4-(2-aminoethylcarbamoyloxy)-L-prolyl-L-phenylglycyl-D-tryptophyl-L-lysyl-4-O-benzyl-L-tyrosyl-L …
Matched Iupac: … (3S,6R,9S,12S,15S,19R,20aS)-9-(4-aminobutyl)-15-benzyl-12-{[4-(benzyloxy)phenyl]methyl}-6-[(1H-indol- …
Matched Salts cas: … 396091-79-5 …
Matched Products: … SIGNIFOR LAR (10 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) …
Matched Iupac: … (3S,6R,9S,12S,15S,19R,20aS)-9-(4-aminobutyl)-15-benzyl-12-{[4-(benzyloxy)phenyl]methyl}-6-[(1H-indol- …
Matched Salts cas: … 396091-79-5 …
Matched Products: … SIGNIFOR LAR (10 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) …
Parachlorophenol
P-chlorophenol is a white crystals with a strong phenol odor. Slightly soluble to soluble in water, depending on the isomer, and denser than water. Noncombustible.
Approved
Matched Synonyms: … 4-chlorphenol ... 4-Chlorophenol …
Matched Iupac: … 4-chlorophenol …
Matched Iupac: … 4-chlorophenol …
Diphenoxylate
A meperidine congener used as an antidiarrheal, usually in combination with atropine. At high doses, it acts like morphine. Its unesterified metabolite difenoxin has similar properties and is used similarly. It has little or no analgesic activity. This medication is classified as a Schedule V under the Controlled Substances Act...
Approved
Illicit
Matched Synonyms: … 2,2-Diphenyl-4-(4-carbethoxy-4-phenylpiperidino)butyronitrile ... Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-4-piperidinecarboxylate ... Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotate …
Matched Iupac: … ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate …
Matched Salts cas: … 3810-80-8 …
Matched Mixtures name: … LOMOTİL 2.5 MG + 0.025 MG / 5 ML ORAL ÇÖZELTİ, 60 ML …
Matched Iupac: … ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate …
Matched Salts cas: … 3810-80-8 …
Matched Mixtures name: … LOMOTİL 2.5 MG + 0.025 MG / 5 ML ORAL ÇÖZELTİ, 60 ML …
Biperiden
A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.
Approved
Investigational
Matched Synonyms: … alpha-5-norbornen-2-yl-alpha-phenyl-1-piperidinepropanol ... 1-Bicyclo[2.2.1]hept-5-en-2-yl-1-phenyl-3-piperidin-1-yl-propan-1-ol ... alpha-bicyclo[2.2.1]hept-5-en-2-yl-alpha-phenyl-1-piperidinepropanol …
Matched Iupac: … 1-{bicyclo[2.2.1]hept-5-en-2-yl}-1-phenyl-3-(piperidin-1-yl)propan-1-ol …
Matched Products: … AKINETON 5 MG/ML IM/IV ENJEKSIYON ICIN ÇÖZELTİ ICEREN AMPUL, 10 ADET ... BIPERIDEN-NEURAX 4 MG ... Akineton 4 mg - Retardtabletten …
Matched Iupac: … 1-{bicyclo[2.2.1]hept-5-en-2-yl}-1-phenyl-3-(piperidin-1-yl)propan-1-ol …
Matched Products: … AKINETON 5 MG/ML IM/IV ENJEKSIYON ICIN ÇÖZELTİ ICEREN AMPUL, 10 ADET ... BIPERIDEN-NEURAX 4 MG ... Akineton 4 mg - Retardtabletten …
Fomepizole
Fomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.
Approved
Vet approved
Matched Synonyms: … 4-methylpyrazol ... 4-methylpyrazole …
Matched Iupac: … 4-methyl-1H-pyrazole …
Matched Products: … Fomepizol SERB 5 mg/ml Konzentrat zur Herstellung einer Infusionslösung …
Matched Iupac: … 4-methyl-1H-pyrazole …
Matched Products: … Fomepizol SERB 5 mg/ml Konzentrat zur Herstellung einer Infusionslösung …
Deserpidine
Deserpidine is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive properties that has been used for the control of high blood pressure and for the relief of psychotic behavior.
Approved
Matched Iupac: … methoxy-17-(3,4,5-trimethoxybenzoyloxy)-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10 …
Matched Salts cas: … 6033-69-8 …
Matched Salts cas: … 6033-69-8 …
Elafibranor
Elafibranor is a dual peroxisome proliferator-activated receptor (PPAR) α and β/δ agonist. On June 10, 2024, elafibranor was granted accelerated approval by the FDA for the treatment of primary biliary cholangitis (PBC).
Approved
Investigational
Matched Synonyms: … PROPANOIC ACID, 2-(2,6-DIMETHYL-4-((1E)-3-(4-(METHYLTHIO)PHENYL)-3-OXO-1-PROPEN-1-YL)PHENOXY)- ... PROPANOIC ACID, 2-(2,6-DIMETHYL-4-(3-(4-(METHYLTHIO)PHENYL)-3-OXO-1-PROPEN-1-YL)PHENOXY)-2-METHYL- …
Matched Iupac: … 2-{2,6-dimethyl-4-[(1E)-3-[4-(methylsulfanyl)phenyl]-3-oxoprop-1-en-1-yl]phenoxy}-2-methylpropanoic acid …
Matched Description: … [A263833] On June 10, 2024, elafibranor was granted accelerated approval by the FDA for the treatment …
Matched Iupac: … 2-{2,6-dimethyl-4-[(1E)-3-[4-(methylsulfanyl)phenyl]-3-oxoprop-1-en-1-yl]phenoxy}-2-methylpropanoic acid …
Matched Description: … [A263833] On June 10, 2024, elafibranor was granted accelerated approval by the FDA for the treatment …
Vismodegib
Vismodegib is an orally active small molecule that inhibits the hedgehog signaling pathway by binding to and inhibiting the transmembrane protein smoothened homologue (SMO).[A258613,A258618,L45803] It was discovered by high-throughput screening of a library of small-molecule compounds and subsequent optimization through medicinal chemistry. Since it targets the hedgehog signaling pathway, vismodegib...
Approved
Investigational
Matched Synonyms: … 2-chloro-N-(4-chloro-3-pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide ... Benzamide, 2-chloro-N-(4-chloro-3-(2-pyridinyl)phenyl)-4-(methylsulfonyl)- …
Matched Iupac: … 2-chloro-N-[4-chloro-3-(pyridin-2-yl)phenyl]-4-methanesulfonylbenzamide …
Matched Iupac: … 2-chloro-N-[4-chloro-3-(pyridin-2-yl)phenyl]-4-methanesulfonylbenzamide …
Diethyltoluamide
Diethyltoluamide (DEET) is the common active ingredient in many insect repellent products. It is widely used to repel biting pests such as mosquitoes and ticks. Every year, DEET formulations are used to protect populations from mosquito-borne illnesses like West Nile Virus, the Zika virus, malaria, and/or tick-borne illnesses like Lyme...
Approved
Acalabrutinib
To date, acalabrutinib has been used in trials studying the treatment of B-All, myelofibrosis, ovarian cancer, multiple myeloma, and Hodgkin lymphoma, among others.
As of October 31, 2017 the FDA approved Astra Zeneca's orally administered Calquence (acalabrutinib, capsules). This Bruton tyrosine kinase (BTK) inhibitor indicated for the treatment of chronic...
Approved
Investigational
Matched Iupac: … 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)benzamide …
Matched Salts cas: … 2641500-53-8 …
Matched Salts cas: … 2641500-53-8 …
Sufentanil
Sufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent. It is administered by the intravenous, epidural and sublingual routes.
Also known as Dsuvia, the sublingual form is used for the management of acute pain in adults that...
Approved
Investigational
Matched Synonyms: … N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)propionanilide ... N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidinyl)-N-phenylpropanamide …
Matched Iupac: … N-[4-(methoxymethyl)-1-[2-(thiophen-2-yl)ethyl]piperidin-4-yl]-N-phenylpropanamide …
Matched Products: … Sufentanil-hameln 10 Mikrogramm/ml Injektions-/Infusionslösung ... Sufentanil Panpharma 5 Mikrogramm/ml Injektionslösung ... Sufentanil-hameln 5 Mikrogramm/ml Injektions-/Infusionslösung …
Matched Iupac: … N-[4-(methoxymethyl)-1-[2-(thiophen-2-yl)ethyl]piperidin-4-yl]-N-phenylpropanamide …
Matched Products: … Sufentanil-hameln 10 Mikrogramm/ml Injektions-/Infusionslösung ... Sufentanil Panpharma 5 Mikrogramm/ml Injektionslösung ... Sufentanil-hameln 5 Mikrogramm/ml Injektions-/Infusionslösung …
Thiabendazole
2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for strongyloidiasis. It has CNS side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of Pharmacology, 1992, p919)
Approved
Vet approved
Matched Synonyms: … 4-(2-benzimidazolyl)thiazole ... 2-(thiazol-4-yl)benzimidazole ... 2-(4-thiazolyl)-1H-benzimidazole …
Matched Iupac: … 2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazole …
Matched Iupac: … 2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazole …
Antipyrine
An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
Approved
Investigational
Matched Synonyms: … 2,3-Dimethyl-1-phenyl-5-pyrazolone …
Matched Mixtures name: … SUPRENIL STERIL OFTALMIK SUSPANSIYON 5 ML …
Matched Products: … TROPEX EAR DROPS 5% w/v …
Matched Mixtures name: … SUPRENIL STERIL OFTALMIK SUSPANSIYON 5 ML …
Matched Products: … TROPEX EAR DROPS 5% w/v …
Dimethicone 410
Dimethicone is a silicone-based polymer used as a moisturizer in different skin OTC products. It is formed by repeated polymeric units of -(CH3)2SiO- with a terminal trimethyl siloxy unit. It is currently recognized by the FDA as a skin protectant OTC ingredient for human use in a concentration of 1-30%....
Approved
Streptococcus pneumoniae type 5 capsular polysaccharide antigen
Streptococcus pneumoniae type 5 capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 5 of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Synonyms: … pneumococcal capsular polysaccharide type 5 vaccine …
Matched Name: … Streptococcus pneumoniae type 5 capsular polysaccharide antigen …
Matched Description: … capsular polysaccharides from the invasive pneumococcal type 5 of *Streptococcus pneumoniae*. ... Streptococcus pneumoniae type 5 capsular polysaccharide antigen is a vaccine that contains highly purified …
Matched Mixtures name: … (MULTIDOSE - 5 DOSE) ... SII PNEUMOSIL Pneumococcal Polysaccharide Conjugate Vaccine (Adsorbed) (10-Valent) SUSPENSION FOR INJECTION ... SII PNEUMOSIL Pneumococcal Polysaccharide Conjugate Vaccine (Adsorbed) (10-Valent) SUSPENSION FOR INJECTION …
Matched Name: … Streptococcus pneumoniae type 5 capsular polysaccharide antigen …
Matched Description: … capsular polysaccharides from the invasive pneumococcal type 5 of *Streptococcus pneumoniae*. ... Streptococcus pneumoniae type 5 capsular polysaccharide antigen is a vaccine that contains highly purified …
Matched Mixtures name: … (MULTIDOSE - 5 DOSE) ... SII PNEUMOSIL Pneumococcal Polysaccharide Conjugate Vaccine (Adsorbed) (10-Valent) SUSPENSION FOR INJECTION ... SII PNEUMOSIL Pneumococcal Polysaccharide Conjugate Vaccine (Adsorbed) (10-Valent) SUSPENSION FOR INJECTION …
Influenza A virus A/Bolivia/559/2013 (H1N1) live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Investigational
Aminosalicylic acid
An antitubercular agent often administered in association with isoniazid. The sodium salt of the drug is better tolerated than the free acid.
Approved
Matched Synonyms: … 4-aminosalicylate ... 4-aminosalicylic acid ... 4-amino-2-hydroxybenzoic acid …
Matched Iupac: … 4-amino-2-hydroxybenzoic acid …
Matched Salts cas: … 133-10-8 ... 133-09-5 ... 6018-19-5 …
Matched Categories: … 4-aminosalicylic acid …
Matched Iupac: … 4-amino-2-hydroxybenzoic acid …
Matched Salts cas: … 133-10-8 ... 133-09-5 ... 6018-19-5 …
Matched Categories: … 4-aminosalicylic acid …
Ribociclib
Ribociclib is a selective cyclin-dependent kinase inhibitor, a class of drugs that help slow the progression of cancer by inhibiting two proteins called cyclin-dependent kinase 4 and 6 (CDK4/6). These proteins, when over-activated, can enable cancer cells to grow and divide too quickly. Targeting CDK4/6 with enhanced precision may play...
Approved
Investigational
Matched Iupac: … 7-cyclopentyl-N,N-dimethyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide …
Matched Description: … that help slow the progression of cancer by inhibiting two proteins called cyclin-dependent kinase 4 …
Matched Salts cas: … 1211443-80-9 ... 1374639-75-4 …
Matched Description: … that help slow the progression of cancer by inhibiting two proteins called cyclin-dependent kinase 4 …
Matched Salts cas: … 1211443-80-9 ... 1374639-75-4 …
Sulpiride
Sulpiride first appeared in published literature in 1967. Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses. Sulpiride is not approved by the FDA, Health Canada, or the EMA; though...
Approved
Investigational
Matched Synonyms: … N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide ... N-((1-Ethyl-2-pyrrolidinyl)methyl)-2-methoxy-5-sulfamoylbenzamide ... 5-(Aminosulfonyl)-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxybenzamide …
Matched Iupac: … N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide …
Matched Iupac: … N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide …
Lamivudine
A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).
Approved
Investigational
Matched Synonyms: … (-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine …
Matched Iupac: … 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one …
Matched Products: … ZEFFIX 5 MG/ML ORAL SOLÜSYON ... LAMIVUDINA SOLUCION ORAL 50 MG/5 ML ... EPIVIR ORAL SOLUTION 10 mg/ml …
Matched Iupac: … 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one …
Matched Products: … ZEFFIX 5 MG/ML ORAL SOLÜSYON ... LAMIVUDINA SOLUCION ORAL 50 MG/5 ML ... EPIVIR ORAL SOLUTION 10 mg/ml …
Cefalotin
Cefalotin is a cephalosporin antibiotic.
Approved
Investigational
Vet approved
Matched Synonyms: … 3-Acetoxymethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid …
Matched Iupac: … (6R,7R)-3-[(acetyloxy)methyl]-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene …
Matched Salts cas: … 58-71-9 …
Matched Products: … KEFOLITIN 1 G/10 ML IV/IM ENJEKTABL FLAKON …
Matched Iupac: … (6R,7R)-3-[(acetyloxy)methyl]-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene …
Matched Salts cas: … 58-71-9 …
Matched Products: … KEFOLITIN 1 G/10 ML IV/IM ENJEKTABL FLAKON …
Spirapril
Spirapril is an ACE inhibitor antihypertensive drug used to treat hypertension. Spirapril is converted to the active spiraprilat after administration. ACE inhibitors are used primarily in treatment of hypertension and congestive heart failure.
Approved
Matched Iupac: … -8-carboxylic acid ... (8S)-7-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-1,4-dithia-7-azaspiro[4.4]nonane …
Matched Salts cas: … 94841-17-5 …
Matched Salts cas: … 94841-17-5 …
Everolimus
Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and...
Approved
Matched Iupac: … (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-( ... hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4- …
Matched Products: … EVERONAT 5 ... AFINITOR (5 MG) ... EVERONAT 10 …
Matched Products: … EVERONAT 5 ... AFINITOR (5 MG) ... EVERONAT 10 …
Sulfadimethoxine
Sulfadimethoxine is a sulfonamide antibiotic. Sulfadimethoxine is used to treat many infections, including treatment of respiratory, urinary tract, enteric, and soft tissue infections. It is most frequently used in veterinary medicine, although it is approved in some countries for use in humans. Sulfadimethoxine inhibits bacterial synthesis of folic acid (pteroylglutamic...
Approved
Vet approved
Withdrawn
Matched Synonyms: … 4-amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide ... 2,6-dimethoxy-4-sulfanilamidopyrimidine ... N(1)-(2,6-Dimethoxy-4-pyrimidinyl)sulfanilamide …
Matched Iupac: … 4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide …
Matched Salts cas: … 1037-50-9 …
Matched Iupac: … 4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide …
Matched Salts cas: … 1037-50-9 …
Light green SF yellowish
Light green SF yellowish is a green triarylmethane dye that is used in the preparation of the staining solution which is widely used as a counterstain. It is used in histological applications and other labratory settings, and usually exists as a disodium salt. The maximum absorption of light green SF...
Approved
Experimental
Matched Synonyms: … Acid green 5 ... Acid Green 5 …
Matched Iupac: … disodium 4-[(4-{ethyl[(3-sulfophenyl)methyl]amino}phenyl)[(1Z,4Z)-4-{ethyl[(3-sulfophenyl)methyl]iminiumyl …
Matched Iupac: … disodium 4-[(4-{ethyl[(3-sulfophenyl)methyl]amino}phenyl)[(1Z,4Z)-4-{ethyl[(3-sulfophenyl)methyl]iminiumyl …
Displaying drugs 1526 - 1550 of 7374 in total