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Displaying drugs 1551 - 1575 of 7365 in total
Atropine
Atropine is an alkaloid originally synthesized from Atropa belladonna. It is a racemic mixture of d-and l-hyoscyamine, of which only l-hyoscyamine is pharmacologically active.[A251670,L42835] Atropine is generally available as a sulfate salt and can be administered by intravenous, subcutaneous, intramuscular, intraosseous, endotracheal and ophthalmic methods. Oral atropine is only available...
Approved
Vet approved
Matched Iupac: … (1R,3S,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 3-hydroxy-2-phenylpropanoate …
Matched Salts cas: … 55-48-1 ... 5908-99-6 …
Matched Products: … CENDO TROPINE 1 % ... Atropine 1% ... ATROPINA 1% …
Matched Salts cas: … 55-48-1 ... 5908-99-6 …
Matched Products: … CENDO TROPINE 1 % ... Atropine 1% ... ATROPINA 1% …
Pixantrone
Pixantrone is an aza-anthracenedione and DNA intercalator which inhibits topoisomerase II. It is similar in structure to anthracyclines such as mitoxantrone, but exerts fewer toxic effects on cardiac tissue. [2] The lower cardio-toxic effects of pixantrone may be explained, in part, by its redox inactivity [3]. Pixantrone does not bind...
Approved
Investigational
Matched Salts cas: … 144675-97-8 …
Mirtazapine
Mirtazapine is a tetracyclic piperazino-azepine antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994. This drug was first manufactured by Organon Inc., and received FDA approval in 1997 for the treatment of major depressive disorder.[T595, L6157] The effects of this...
Approved
Matched Synonyms: … 6-Azamianserin …
Matched Iupac: … 5-methyl-2,5,19-triazatetracyclo[13.4.0.0^{2,7}.0^{8,13}]nonadeca-1(15),8,10,12,16,18-hexaene …
Matched Description: … [T595, L6157] The effects of this drug may be observed as early as 1 week after beginning therapy. …
Matched Products: … MİTAZEN 6 MG/2 ML İ.V. İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ İÇEREN AMPUL, 10 AMPUL …
Matched Iupac: … 5-methyl-2,5,19-triazatetracyclo[13.4.0.0^{2,7}.0^{8,13}]nonadeca-1(15),8,10,12,16,18-hexaene …
Matched Description: … [T595, L6157] The effects of this drug may be observed as early as 1 week after beginning therapy. …
Matched Products: … MİTAZEN 6 MG/2 ML İ.V. İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ İÇEREN AMPUL, 10 AMPUL …
Famotidine
Famotidine is a competitive histamine-2 (H2) receptor antagonist that works to inhibit gastric acid secretion. It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children. Compared to other H2 receptor antagonists, famotidine displays high selectivity towards...
Approved
Matched Synonyms: … (1-Amino-3-(((2-((diaminomethylene)amino)-4-thiazolyl)methyl)thio)propylidene)sulfamide …
Matched Mixtures name: … TRIGAST 10 MG/800 MG/165 MG ÇİĞNEME TABLETİ, 6 ADET ... ACİDPASS 10 MG/800 MG/165 MG ÇİĞNEME TABLETİ, 6 ADET …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring …
Matched Products: … Zantac 360 1 per blister 6 blisters ... Zantac 360 2 per blister 6 blisters …
Matched Mixtures name: … TRIGAST 10 MG/800 MG/165 MG ÇİĞNEME TABLETİ, 6 ADET ... ACİDPASS 10 MG/800 MG/165 MG ÇİĞNEME TABLETİ, 6 ADET …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring …
Matched Products: … Zantac 360 1 per blister 6 blisters ... Zantac 360 2 per blister 6 blisters …
Tetracosactide
Tetracosactide (also known as Cosyntropin) is a synthetic peptide that is identical to the 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone. ACTH (1-24), a segment similar in all species, contains the biological activity that stimulates production of corticosteroids in the adrenal cortex. Tetracosactide exhibits the same...
Approved
Matched Synonyms: … ATCH (1-24) ... corticotropin-(1-24) ... beta(1-24)-corticotrophin …
Matched Iupac: … (2S)-1-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-6-amino ... -2-{2-[(2S)-2-{[(2S)-1-[(2S)-6-amino-2-{2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S …
Matched Description: … ACTH (1-24), a segment similar in all species, contains the biological activity that stimulates production …
Matched Salts cas: … 22633-88-1 …
Matched Products: … SYNACTHEN DEPOT 1 MG AMPUL, 1 ADET ... Synacthen 0,25 mg/1 ml Ampulle …
Matched Iupac: … (2S)-1-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-6-amino ... -2-{2-[(2S)-2-{[(2S)-1-[(2S)-6-amino-2-{2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S …
Matched Description: … ACTH (1-24), a segment similar in all species, contains the biological activity that stimulates production …
Matched Salts cas: … 22633-88-1 …
Matched Products: … SYNACTHEN DEPOT 1 MG AMPUL, 1 ADET ... Synacthen 0,25 mg/1 ml Ampulle …
Deutetrabenazine
Deutetrabenazine is a novel, highly selective vesicular monoamine transporter 2 (VMAT2) inhibitor indicated for the management of chorea associated with Huntington’s disease. It is a hexahydro-dimethoxybenzoquinolizine derivative and a deuterated DB04844 . The presence of deuterium in deutetrabenazine increases the half-lives of the active metabolite and prolongs their pharmacological activity...
Approved
Investigational
Ticarcillin
An antibiotic derived from penicillin similar to carbenicillin in action.
Approved
Investigational
Vet approved
Matched Synonyms: … (2S,5R,6R)-6-{[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0 …
Matched Iupac: … (2S,5R,6R)-6-[(2R)-2-carboxy-2-(thiophen-3-yl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0 …
Matched Salts cas: … 29457-07-6 …
Matched Iupac: … (2S,5R,6R)-6-[(2R)-2-carboxy-2-(thiophen-3-yl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0 …
Matched Salts cas: … 29457-07-6 …
Saquinavir
Saquinavir is an HIV-1 protease inhibitor used in combination with ritonavir and other antiretrovirals for the treatment of human immunodeficiency virus-1 (HIV-1) infection. In 1995 it became the first protease inhibitor approved by the FDA, followed shortly by ritonavir in 1996, and remains in clinical use today due to a...
Approved
Investigational
Matched Iupac: … (2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-decahydroisoquinolin-2-yl]-3-hydroxy-1-phenylbutan …
Matched Description: … for the treatment of human immunodeficiency virus-1 (HIV-1) infection. ... Saquinavir is an HIV-1 protease inhibitor used in combination with [ritonavir] and other antiretrovirals …
Matched Description: … for the treatment of human immunodeficiency virus-1 (HIV-1) infection. ... Saquinavir is an HIV-1 protease inhibitor used in combination with [ritonavir] and other antiretrovirals …
Metacycline
A broad-spectrum semisynthetic antibiotic related to tetracycline but excreted more slowly and maintaining effective blood levels for a more extended period.
Approved
Investigational
Matched Synonyms: … 6-Demethyl-6-deoxy-5-hydroxy-6-methylenetetracycline ... 6-Deoxy-6-demethyl-6-methylene-5-oxytetracycline ... 6-Methyleneoxytetracycline …
Matched Iupac: … (4S,4aR,5S,5aR,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methylidene-1,11-dioxo-1,4,4a,5,5a …
Matched Iupac: … (4S,4aR,5S,5aR,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methylidene-1,11-dioxo-1,4,4a,5,5a …
Dorzolamide
Dorzolamide is a non-bacteriostatic sulfonamide derivative and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular hypertension. It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. Unlike oral CA inhibitors, dorzolamide...
Approved
Matched Synonyms: … (4S,6S)-4-ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic ... 4-Ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid ... (4S,trans)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide …
Matched Iupac: … (2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H-1lambda6-thieno[2,3-b]thiopyran-6-sulfonamide …
Matched Mixtures name: … TOMEC %2 + %0.5 STERIL OFTALMIK ÇÖZELTİ, 6 ML ... DORZASOPT GÖZ DAMLASI ,1 ŞIŞE ... XOLATIM %2+ %0,5 GÖZ DAMLASI, ÇÖZELTİ ,5 ML,1 ŞİŞE …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … DORZAMED %2 GÖZ DAMLASI ,1 ŞIŞE ... XOLADOR %2 GÖZ DAMLASI ,5 ML, 1 ŞIŞE …
Matched Iupac: … (2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H-1lambda6-thieno[2,3-b]thiopyran-6-sulfonamide …
Matched Mixtures name: … TOMEC %2 + %0.5 STERIL OFTALMIK ÇÖZELTİ, 6 ML ... DORZASOPT GÖZ DAMLASI ,1 ŞIŞE ... XOLATIM %2+ %0,5 GÖZ DAMLASI, ÇÖZELTİ ,5 ML,1 ŞİŞE …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … DORZAMED %2 GÖZ DAMLASI ,1 ŞIŞE ... XOLADOR %2 GÖZ DAMLASI ,5 ML, 1 ŞIŞE …
Cupric Chloride
Cupric chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to solutions for Total Parenteral Nutrition (TPN).
Approved
Investigational
Everolimus
Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and...
Approved
Matched Iupac: … (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-( …
Matched Products: … Aderolio 1 mg – Tabletten ... CERTICAN TABLETS 1 MG ... Certican 1 mg - Tabletten …
Matched Products: … Aderolio 1 mg – Tabletten ... CERTICAN TABLETS 1 MG ... Certican 1 mg - Tabletten …
Panobinostat
Panobinostat is an oral deacetylace (DAC) inhibitor approved on February 23, 2015 by the FDA for the treatment of multiple myeloma. The approval was accelerated based on progression-free survival, therefore confirmatory trials by the sponsor to demonstrate clinical efficacy in multiple myeloma treatment are in progress of being conducted. Panobinostat...
Approved
Investigational
Bendroflumethiazide
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
Approved
Matched Synonyms: … 6-trifluoromethyl-3-benzyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide ... ±-3-benzyl-3,4-dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide …
Matched Iupac: … 3-benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Iupac: … 3-benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Efbemalenograstim alfa
Efbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating factor (G-CSF) due to the addition of the Fc portion of human IgG2, allowing for once-per-cycle administration.[L48852,A262167] As endogenous G-CSF mediates the differentiation of hematopoietic stem cells into granulocytes and eventually neutrophils, the administration of recombinant G-CSF like efbemalenograstim...
Approved
Elexacaftor
Elexacaftor (previously VX-445) is a small molecule, next-generation corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) protein. It received FDA approval in October 2019 in combination with tezacaftor and ivacaftor as the combination product TrikaftaTM. Elexacaftor is considered a next-generation CFTR corrector as it possesses both a different structure...
Approved
Investigational
Matched Iupac: … N-[(1,3-dimethyl-1H-pyrazol-4-yl)sulfonyl]-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl ... ]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide …
Matched Description: … who are either homo- _or_ heterozygous for the _F508del-CFTR_ gene - this represents approximately 70 …
Matched Description: … who are either homo- _or_ heterozygous for the _F508del-CFTR_ gene - this represents approximately 70 …
Ioflupane I-123
Ioflupane (I-123) is a radiopharmaceutical used to image dopamine neurons and diagnose Parkinsonian syndromes.
Approved
Matched Iupac: … methyl (1R,2S,3S,5S)-8-(3-fluoropropyl)-3-[4-(¹²³I)iodophenyl]-8-azabicyclo[3.2.1]octane-2-carboxylate …
Streptococcus pneumoniae type 6a capsular polysaccharide antigen
Approved
Experimental
Matched Mixtures name: … Pneumococcal Polysaccharide Conjugate Vaccine (Adsorbed) (10-Valent) SUSPENSION FOR INJECTION (SINGLE DOSE - 1 …
Nedosiran
Nedosiran is an RNA interference targeting hepatic lactate dehydrogenase, the enzyme responsible for the conversion of glyoxylate to oxalate. Oxalate, particularly calcium oxalate, precipitation is the main cause of kidney stones formation; therefore, blocking the production of oxalate can help alleviate renal symptoms. Nedosiran was approved by the FDA on...
Approved
Investigational
Matched Description: … urinary oxalate levels in children 9 years of age and older and adults with primary hyperoxaluria type 1 …
Anagrelide
Anagrelide is a platelet-reducing agent used to lower dangerously elevated platelet levels (i.e. to treat thrombocythemia) in patients with myeloproliferative neoplasms. It is an oral imidazoquinazoline that was first approved for use in the US in 1997. It appears to carry a better response rate than other thrombocythemia treatments (e.g....
Approved
Matched Products: … ANAGRELID RATIO 1 MG ... Anagrelid Nordic 1 mg Tabletten ... Anagrelid ratiopharm 1 mg Hartkapseln …
Lansoprazole
Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole. It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD) along with other pathologies...
Approved
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Adapalene
Acne vulgaris is a multifactorial disorder of the pilosebaceous unit involving increased sebum production, inflammation, and hyperproliferation/hyperkeratinization of the follicular infundibulum. It is also associated with Cutibacterium acnes (also known as Propionibacterium acnes). Adapalene is a third-generation topical retinoid used for the treatment of acne vulgaris. Adapalene has similar efficacy...
Approved
Matched Synonyms: … 6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acid …
Matched Iupac: … 6-[3-(adamantan-1-yl)-4-methoxyphenyl]naphthalene-2-carboxylic acid …
Matched Mixtures name: … Adapalene 0.3% / Benzoyl Peroxide 2.5% / Clindamycin 1% ... Adapalene 0.1% / Benzoyl Peroxide 2.5% / Clindamycin 1% …
Matched Products: … ACNEFFERİN %0,1 JEL, 1 ADET (30 G) …
Matched Iupac: … 6-[3-(adamantan-1-yl)-4-methoxyphenyl]naphthalene-2-carboxylic acid …
Matched Mixtures name: … Adapalene 0.3% / Benzoyl Peroxide 2.5% / Clindamycin 1% ... Adapalene 0.1% / Benzoyl Peroxide 2.5% / Clindamycin 1% …
Matched Products: … ACNEFFERİN %0,1 JEL, 1 ADET (30 G) …
Oxacillin
An antibiotic similar to flucloxacillin used in resistant staphylococci infections.
Approved
Investigational
Matched Synonyms: … (2S,5R,6R)-3,3-dimethyl-6-{[(5-methyl-3-phenylisoxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo …
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-6-(5-methyl-3-phenyl-1,2-oxazole-4-amido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane …
Matched Products: … OXACILINA 1 G ... OXACILINA 1 G POLVO ESTERIL PARA SOLUCION INYECTABLE. ... OXACILINA 1 G POLVO ESTÉRIL PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-6-(5-methyl-3-phenyl-1,2-oxazole-4-amido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane …
Matched Products: … OXACILINA 1 G ... OXACILINA 1 G POLVO ESTERIL PARA SOLUCION INYECTABLE. ... OXACILINA 1 G POLVO ESTÉRIL PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Rolapitant
Rolapitant is a potent, highly selective, long-acting Neurokinin-1 (NK-1) receptor antagonist approved for the prevention of delayed chemotherapy-induced nausea and vomiting (CINV) in adults. Delayed-phase CINV typically occurs >24 hours after chemotherapy treatment and is principally mediated by Neurokinin-1 and its ligand Substance P, which is released in the gut...
Approved
Investigational
Matched Iupac: … (5S,8S)-8-{[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl}-8-phenyl-1,7-diazaspiro[4.5]decan-2 …
Matched Description: … Neurokinin-1 is also known as Tachykinin Receptor 1 (TACR1), Neurokinin 1 Receptor (NK1R), and Substance ... Rolapitant is a potent, highly selective, long-acting Neurokinin-1 (NK-1) receptor antagonist approved ... CINV typically occurs >24 hours after chemotherapy treatment and is principally mediated by Neurokinin-1 …
Matched Salts cas: … 858102-79-1 …
Matched Categories: … Neurokinin 1 Antagonists ... Neurokinin-1 Receptor Antagonists ... Substance P/Neurokinin-1 Receptor Antagonist …
Matched Description: … Neurokinin-1 is also known as Tachykinin Receptor 1 (TACR1), Neurokinin 1 Receptor (NK1R), and Substance ... Rolapitant is a potent, highly selective, long-acting Neurokinin-1 (NK-1) receptor antagonist approved ... CINV typically occurs >24 hours after chemotherapy treatment and is principally mediated by Neurokinin-1 …
Matched Salts cas: … 858102-79-1 …
Matched Categories: … Neurokinin 1 Antagonists ... Neurokinin-1 Receptor Antagonists ... Substance P/Neurokinin-1 Receptor Antagonist …
Auranofin
Auranofin is a gold salt that is capable of eliciting pharmacologic actions that suppress inflammation and stimulate cell-mediated immunity. It has subsequently been listed by the World Health Organization as a member of the antirheumatic agent category. Auranofin appears to induce heme oxygenase 1 (HO-1) mRNA. Heme oxygenase 1 is...
Approved
Investigational
Matched Synonyms: … (1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate ... 2,3,4,6-Tetra-O-acetyl-1-thio-beta-D-glucopyranosato-S (triethylphosphine)gold …
Matched Iupac: … [(2R,3R,4S,5R,6S)-3,4,5-tris(acetyloxy)-6-{[(triethyl-lambda5-phosphanylidene)aurio]sulfanyl}oxan-2-yl …
Matched Description: … Auranofin appears to induce heme oxygenase 1 (HO-1) mRNA. ... Heme oxygenase 1 is an inducible heme-degrading enzyme with anti-inflammatory properties. …
Matched Iupac: … [(2R,3R,4S,5R,6S)-3,4,5-tris(acetyloxy)-6-{[(triethyl-lambda5-phosphanylidene)aurio]sulfanyl}oxan-2-yl …
Matched Description: … Auranofin appears to induce heme oxygenase 1 (HO-1) mRNA. ... Heme oxygenase 1 is an inducible heme-degrading enzyme with anti-inflammatory properties. …
Displaying drugs 1551 - 1575 of 7365 in total