Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Displaying drugs 151 - 175 of 14778 in total

Bisacodyl

Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Iupac: … 4-{[4-(acetyloxy)phenyl](pyridin-2-yl)methyl}phenyl acetate …
Matched Description: … [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-( …
Matched Mixtures name: … HalfLytely and Bisacodyl ... HalfLytely and Bisacodyl ... GaviLyte-H and Bisacodyl …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up womens laxative ... Up and Up Gentle Laxative ... Foster and Thrive Gentle Laxative …

Cimetidine

A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Description: … It inhibits gastric acid secretion, as well as pepsin and gastrins output. …
Matched Salts name: … Cimetidine hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Metabolic Side Effects of Drugs and Substances ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … Up and Up Acid Reducer ... Cimetidine Hydrochloride ... Cimetidine Hydrochloride Oral Solution …

Hydrocortisone

Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. Hydrocortisone was granted FDA approval on 5 August 1952.
Approved
Vet approved
Matched Description: … [A188387] Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions. ... [L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named …
Matched Mixtures name: … Neomycin and Polymyxin B Sulfates and Hydrocortisone ... Neomycin and Polymyxin B Sulfates and Hydrocortisone ... Neomycin and Polymyxin B Sulfates and Hydrocortisone …
Matched Categories: … Alimentary Tract and Metabolism ... Sex Hormones and Insulins ... hydrocortisone and mydriatics ... Hydrocortisone and derivatives ... hydrocortisone and antiseptics …
Matched Products: … Rodan and Fields Soothe ... Itch and Rash Cream ... Up and Up Anti Itch …

Tioconazole

Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus". Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In...
Approved
Matched Description: … Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. ... Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus …
Matched Salts name: … Tioconazole hydrochloride …
Matched Categories: … Imidazole and Triazole Derivatives ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Metabolic Side Effects of Drugs and Substances ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Up and up tioconazole 1 ... Foster and Thrive Tioconazole …

Betahistine

Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408] Betahistine is a histamine-like antivertigo drug used for treating symptoms associated with Ménière's disease. It is thought to...
Approved
Investigational
Matched Iupac: … methyl[2-(pyridin-2-yl)ethyl]amine …
Matched Description: … It has a significant impact on both the physical and social functioning of affected individuals. ... Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing …
Matched Salts name: … Betahistine hydrochloride …
Matched Products: … BETAHISTINE HYDROCHLORIDE …

Paroxetine

Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others. It was approved by the FDA in the early 1990s and marketed by SmithKline...
Approved
Investigational
Matched Description: … of serotonin reuptake and has little effect on other neurotransmitters. ... [T653] It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham. ... uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and …
Matched Salts name: … Paroxetine hydrochloride ... Paroxetine hydrochloride hemihydrate …
Matched Products: … Paroxetine Hydrochloride ... Paroxetine Hydrochloride CR ... Paroxetine Hydrochloride Anhydrous …

Drometrizole trisiloxane

Drometrizole trisiloxane is a photostable UVA and UVB light filter [A33069, L2780, L2781, L2782, L2783, F81]. The compound is a lipophilic benzotriazole derivative marketed as Meroxyl XL by L'Oreal, although sunscreens with drometrizole trisiloxane are currently only approved for use in the EU, Canada, Australia, and Japan, among other countries....
Approved
Matched Description: … Drometrizole trisiloxane is a photostable UVA and UVB light filter [A33069, L2780, L2781, L2782, L2783 ... scientific record is not sufficient to establish the compound as being generally recognized as safe and ... sunscreens with drometrizole trisiloxane are currently only approved for use in the EU, Canada, Australia, and …
Matched Mixtures name: … Kiehls Activated Sun Protector Sunscreen SPF 50 For Face and Body For All Skin Types ... Kiehls Activated Sun Protector Sunscreen SPF 30 For Face and Body For All Skin Types …
Matched Categories: … Silicon Compounds …

Leuprolide

Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH). Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, which helps to increase its circulating half-life from three to four minutes to approximately three hours. As a GnRH mimic, leuprolide is capable of binding to...
Approved
Investigational
Matched Description: … downstream modulation of both gonadotropin hormone and sex steroid levels. ... [A203222] As a GnRH mimic, leuprolide is capable of binding to the GnRH receptor (GnRHR) and inducing ... [L13850] Since this initial approval, various long-acting intramuscular and subcutaneous products have …
Matched Categories: … Hormones and Related Agents ... Amino Acids, Peptides, and Proteins ... leuprorelin and bicalutamide ... Antineoplastic and Immunomodulating Agents …
Matched Products: … POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 45mg ... POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 7.5mg ... POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 22.5mg …

Sevelamer

Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Approved
Matched Salts name: … Sevelamer hydrochloride …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Matched Products: … Sevelamer Hydrochloride ... Sevelamer hydrochloride …

Bentonite

Approved
Matched Categories: … Silicon Compounds …

Iodine

Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A192159]
Approved
Investigational
Matched Description: … Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may ... Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer. …
Matched Mixtures name: … Potassium and Iodine Tab ... Potassium and Iodine Tab ... Essential Vitamins and Minerals …
Matched Categories: … Diet, Food, and Nutrition ... Herbs and Natural Products ... Antiseptics and Disinfectants …
Matched Products: … XENETIX 300-50ML SOLN FOR INTRAVASCULAR, INTRAUTERINE AND INTRA-ARTICULAR INJ ... XENETIX 300-100ML SOLN FOR INTRAVASCULAR, INTRAUTERINE AND INTRA-ARTICULAR INJ …

Vardenafil

Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and an oral therapy for the treatment of erectile dysfunction.[L45563,L45568] During sexual stimulation, nitric oxide (NO) is released from nerve endings and endothelial cells in the corpus cavernosum, activating the enzyme guanylate cyclase and increasing the...
Approved
Matched Description: … selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and ... cells in the corpus cavernosum, activating the enzyme guanylate cyclase and increasing the synthesis ... Compared to [sildenafil] and [tadalafil], vardenafil is a more potent inhibitor of PDE5; however, its …
Matched Salts name: … Vardenafil hydrochloride …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … Vardenafil hydrochloride ... Vardenafil Hydrochloride …

Tapentadol

Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake.[A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011....
Approved
Matched Salts name: … Tapentadol hydrochloride …

Sodium acetate

Sodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. Sodium acetate could be used as additives in food, industry, concrete manufacture, heating pads and in buffer solutions. Medically, sodium acetate is important component as an electrolyte replenisher when given intravenously. It is mainly indicated to correct...
Approved
Investigational
Matched Description: … It can be used also in metabolic acidosis and for urine alkalinization. ... Sodium acetate could be used as additives in food, industry, concrete manufacture, heating pads and in …
Matched Mixtures name: … Plasma-Lyte 148 and dextrose ... Normosol-R and Dextrose ... Plasma-Lyte M and Dextrose …
Matched Categories: … Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …

Trichlormethiazide

A thiazide diuretic with properties similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p830)
Approved
Vet approved
Matched Categories: … trichlormethiazide and potassium ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... trichlormethiazide and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents …

Sodium zirconium cyclosilicate

Sodium zirconium cyclosilicate is approved as the trade product Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a powder for oral suspension that acts as a highly selective potassium removing agent. It is administered orally and is odorless, tasteless, and stable at room temperature. Approval...
Approved
Investigational
Matched Description: … [L2933] It is administered orally and is odorless, tasteless, and stable at room temperature. ... Approval of the medication is supported by data from three double-blind, placebo-controlled trials and ... two open-label trials which showed that the onset of action was approximately 1.0 hour and the median …
Matched Categories: … Silicon Compounds ... Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …

Carglumic acid

Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl glutamate synthase. This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and cause neurologic problems, cerebral edema, coma, and death. Carglumic acid was...
Approved
Matched Description: … Food and Drug Administration (FDA) on 18 March 2010. ... cause neurologic problems, cerebral edema, coma, and death. ... disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and …
Matched Categories: … Amino Acids and Derivatives ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …

Minoxidil

A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Approved
Investigational
Matched Description: … potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and …
Matched Categories: … Skin and Mucous Membrane Agents …
Matched Products: … Up and Up Minoxidil ... Up and Up minoxidil ... Berkley and Jensen Minoxidil …

Methyldopa

Methyldopa, or α-methyldopa, is a centrally acting sympatholytic agent and an antihypertensive agent. It is an analog of DOPA (3,4‐hydroxyphenylanine), and it is a prodrug, meaning that the drug requires biotransformation to an active metabolite for therapeutic effects. Methyldopa works by binding to alpha(α)-2 adrenergic receptors as an agonist, leading...
Approved
Matched Description: … Methyldopa, or α-methyldopa, is a centrally acting sympatholytic agent and an antihypertensive agent. ... [A231784] It is an analog of DOPA (3,4‐hydroxyphenylanine), and it is a prodrug, meaning that the drug ... [A1499] Methyldopa exists in two isomers D-α-methyldopa and L-α-methyldopa, which is the active form. …
Matched Mixtures name: … Methyldopa and Hydrochlorothiazide ... Methyldopa and Hydrochlorothiazide ... Methyldopa and Hydrochlorothiazide …
Matched Salts name: … Methyldopa hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Methyldopate Hydrochloride …

Tetryzoline

Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral alpha (α)-adrenergic properties. Available since the 1950s, tetryzoline is a selective α1-receptor agonist that is used as an ocular and nasal decongestant. Tetryzoline is found in a wide array of over-the-counter eye drops, including the most...
Approved
Matched Description: … such as [povidone], [polyethylene glycol 400], [dextran], and [zinc sulfate]. ... scrutinized for possible drug overdose and toxicity from accidental ingestion. ... Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral …
Matched Mixtures name: … Up and Up Ultra Itchy Relief ... Redness reliever and Lubricant ... Seasonal itchy and Red eye relief …
Matched Salts name: … Tetrahydrozoline hydrochloride …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Foster and Thrive Original Formula Eye Drops ... Walgreens Eye Drops Original 15mL and twin pack …

Vernakalant

Vernakalant was developed by Cardiome Pharma as as an antiarrhythmic drug intended for rapid conversion of atrial fibrillation to sinus rhythm. It acts as an atypical class III antiarrhythmic drug that potentiates its effect in higher heart rates. Intravenous formulation was approved in Europe in September 2010 as Brinavess and...
Approved
Investigational
Matched Description: … Intravenous formulation was approved in Europe in September 2010 as Brinavess and in Canada in April …
Matched Salts name: … Vernakalant hydrochloride …

Insulin aspart

Insulin aspart is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … and proteolysis among many other functions. ... tissues such as the liver, fat cells, and skeletal muscle. ... can result in symptoms such as fatigue, headache, blurred vision, and increased thirst. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin degludec and insulin aspart ... Insulins and Analogues for Injection, Fast-Acting ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … .Insulin Aspart Protamine and Insulin Aspart ... Insulin Aspart Protamine and Insulin Aspart Mix 70/30 …

Bacitracin

Bacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A. The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy. Bacitracin was granted FDA approval on 29 July 1948.[A181997,L7748]
Approved
Vet approved
Matched Mixtures name: … Neomycin and Polymyxin B Sulfates and Bacitracin Zinc ... Neomycin and Polymyxin B Sulfates and Bacitracin Zinc ... Neomycin and Polymyxin B Sulfates and Bacitracin Zinc …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Up and Up First Aid Antibiotic ... Up and Up Bacitracin first aid …

Ziprasidone

Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior. These mental illnesses can often be accompanied by comorbidities such as depression and substance abuse, and can significantly impact the quality of life of patients and caregivers. Luckily, several treatment options for psychotic disorders have been...
Approved
Matched Description: … abuse, and can significantly impact the quality of life of patients and caregivers. ... Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior ... [A180748] It can effectively reduce the rate and time of relapses in schizophrenia, and can be used to …
Matched Salts name: … Ziprasidone hydrochloride …
Matched Products: … Ziprasidone Hydrochloride ... Ziprasidone hydrochloride …

Cholecalciferol

Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are...
Approved
Nutraceutical
Matched Description: … C23 and has an additional methyl group at C24 [L5689]. ... the plant-derived form, vitamin D2 (ergocalciferol), are considered the main forms of vitamin d and ... of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and …
Matched Mixtures name: … Active Calcium Plus Magnesium, Vitamin D and Silicon ... Actical Plus Calcium-magnesium-vitamin D3-silicon Chewable ... Usana Optimizer Actical Plus Calcium-magnesium-vitamin D3-silicon Tablets …
Matched Categories: … Alimentary Tract and Metabolism ... Vitamin D and Analogues ... Diet, Food, and Nutrition ... Calcium-Regulating Hormones and Agents ... ibandronic acid and colecalciferol …
Displaying drugs 151 - 175 of 14778 in total