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Displaying drugs 1726 - 1750 of 1858 in total

Aldesleukin

Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. This recombinant form differs from...
Approved
Matched Description: … Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression ... This recombinant form differs from native interleukin-2 in the following ways: a) Aldesleukin is not ... glycosylated because it is derived from E. coli; b) the molecule has no N-terminal alanine; the codon for …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … PROLEUKIN POWDER FOR INFUSION 18 miu/vial …

Asparaginase Escherichia coli

Asparaginase derived from Escherichia coli (L-asparagine amidohydrolase, EC 3.5.1.1) is an enzyme responsible for the metabolism of L-asparagine, by catalyzing L-asparagine into L-aspartic acid and ammonia. It also facilitates the production of oxaloacetate which is needed for general cellular metabolism. Asparaginase from E. coli has clinically shown to exhibit antitumor...
Approved
Investigational
Matched Description: … the metabolism of L-asparagine, by catalyzing L-asparagine into L-aspartic acid and ammonia. ... derived from _Escherichia coli_ (L-asparagine amidohydrolase, EC 3.5.1.1) is an enzyme responsible for ... It also facilitates the production of oxaloacetate which is needed for general cellular metabolism. …
Matched Categories: … Enzymes and Coenzymes ... Antineoplastic and Immunomodulating Agents …
Matched Products: … LEUNASE FOR INJECTION 10,000 iu/vial …

Gadobutrol

Gadobutrol is a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast agent) used in magnetic resonance imaging (MRI) in adults and children older than 2 years of age. Due to its physicochemical properties, gadobutrol is formulated at twice the gadolinium ion concentration compared to other GBCA and thus requires a lesser...
Approved
Matched Description: … macrocyclic GBCA (gadolinium-based contrast agent) used in magnetic resonance imaging (MRI) in adults and ... properties, gadobutrol is formulated at twice the gadolinium ion concentration compared to other GBCA and …
Matched Products: … GADOVIST 1.0 MMOL/ML SOLUTION FOR INJECTION …

Carboplatin

Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma. Early clinical studies of carboplatin were performed in 1982. Carboplatin was developed as an analog of cisplatin with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.
Approved
Matched Description: … [A230523] Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Indicators and Reagents …
Matched Products: … CARBOPLATINO SALUS ... KEMOCARB CONCENTRATE FOR SOLUTION FOR INFUSION 10MG/ML ... CARBOL - Carboplatin Concentrate for Solution for Infusion 10mg/ml …

Aztreonam

A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
Approved
Matched Description: … , bladder, and kidneys. ... It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … AZACTAM FOR INJECTION 1 g/vial …

Somatostatin

Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino acid residues that regulates the endocrine system. It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also generated in the hypothalamus, where...
Approved
Investigational
Matched Description: … Prosomastatin is further process into two active forms, somatostatin-14 (SST-14) and somatostatin-28 ... Somatostatin has been used in the clinical setting for the diagnosis of acromegaly and gastrointestinal ... It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Somatostatin and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … STILAMIN 3000 FOR INJECTION 3 mg/ampoule …

Mitoxantrone

An anthracenedione-derived antineoplastic agent.
Approved
Investigational
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … MITOXANTRONE SALUS ... MITOXANTRONE BAXTER SOLUTION FOR INJECTION 20MG/10ML (2MG/ML) …

(1R,2R,3S,4R,6S)-3,4,6-Trihydroxy-5-{[(S)-hydroxy(3-hydroxy-2-oxopropoxy)phosphoryl]oxy}-1,2-cyclohexanediyl bis[dihydrogen (phosphate)]

Experimental
Matched Name: … Trihydroxy-5-{[(S)-hydroxy(3-hydroxy-2-oxopropoxy)phosphoryl]oxy}-1,2-cyclohexanediyl bis[dihydrogen (phosphate …

Remifentanil

Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.
Approved
Matched Description: … pain relief and adjunctive to an anaesthetic. ... causes respiratory depression and analgesia. ... a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and …
Matched Categories: … Hypnotics and Sedatives ... Fentanyl and fentanyl analogues …
Matched Products: … Remifentanil for Injection ... ULTIVA FOR INJECTION 1 mg/vial ... Remifentanil Hydrochloride for Injection …

Cefprozil

Cefprozil is a cephalosporin antibiotic that is commonly employed to treat a variety of bacterial infections, including those of the ear and skin, bronchitis, and others.
Approved
Matched Description: … skin, bronchitis, and others. ... antibiotic that is commonly employed to treat a variety of bacterial infections, including those of the ear and …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Cefprozil Powder for Oral Suspension ... Cefzil Powder for Oral Suspension-125mg/5ml ... Cefzil Powder for Oral Suspension-250 Mg/ 5 Ml …

Ornithine

Produced during the urea cycle, ornithine is an amino acid produced from the splitting off of urea from arginine. L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine.
Approved
Nutraceutical
Matched Description: … L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine …
Matched Categories: … Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Amino Acids, Peptides, and Proteins …
Matched Products: … Hepa-Merz 3000mg Granulate/sachet for oral solution …

Nicardipine

A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents. [PubChem]
Approved
Investigational
Matched Description: … It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without ... It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents ... A potent calcium channel blockader with marked vasodilator action. …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Antihypertensive Agents Indicated for Hypertension ... Calcium Channel Blockers ... Calcium Channel Blockers (Dihydropyridine) ... Selective Calcium Channel Blockers With Mainly Vascular Effects …
Matched Products: … Nicardiin 1mg/ml Solution for Infusion …

Protamine sulfate

Since it's earliest discovery in salmon rine sperm heads in the late 1800's to its formal introduction via US FDA approval in 1939, protamine sulfate has occupied an important therapeutic niche as perhaps the only viable option for reversing the anticoagulant effect of heparin use for over 77 years [A174778,...
Approved
Matched Description: … Although current up to date reviews and studies continue to search for new therapeutic alternatives to ... kidney tissue damage, and anaphylactic reaction, amongst others [A174778, L5371]. ... are sometimes considered high and limited, respectively [A174778, A174781]. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Protamine Sulphate 10mg/ml Solution for Injection …

Thiamphenicol

Experimental
Investigational
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … BIOTHICOL FORTE ... FOSICOL FORTE ... SENDICOL FORTE …

Urea C-13

Urea 13C is a urea molecule radiolabelled with the non-radioactive element carbon-13. It is currently used for the Urea Breath Test (UBT) and is available as a rapid diagnostic test (marketed as Pranactin-Citric) for the detection of Helicobacter pylori infections. H pylori is a common stomach bacteria that has been...
Approved
Matched Description: … Radiolabelled urea is available in two forms as 13C and 14C. ... It is currently used for the Urea Breath Test (UBT) and is available as a rapid diagnostic test (marketed ... Exhaled breath samples can then be collected and measured for the presence of radioactivity. …
Matched Products: … Helicobacter Test Infai for Children Of The Age 3-11 …

Dyclonine

Dyclonine is an oral anaesthetic found in Sucrets, an over the counter throat lozenge. It may also be found in some Cepacol sore throat spray products.
Approved
Matched Mixtures name: … Benzethonium Chloride and Dyclonine Hydrochloride ... Benzethonium chloride and Dyclonine hydrochloride ... Benzethonium Chloride and Dyclonine Hydrochloride …
Matched Products: … Sucrets for Kids …

Typhoid Vi polysaccharide vaccine

Typhoid Vi polysaccharide vaccine is a vaccine that is administered intramuscularly. It is an active immunization for the prevention of typhoid fever caused by S typhi and is approved for use in persons two years of age or older. The vaccine contains the purified cell surface Vi polysaccharide extracted from...
Approved
Matched Description: … It is an active immunization for the prevention of typhoid fever caused by S typhi and is approved for …
Matched Categories: … Antiinfectives for Systemic Use …
Matched Products: … Typhim VI Solution for Injection in Multidose …

Mycophenolate mofetil

Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified as a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH). This drug is an immunosuppressant combined with drugs such as Cyclosporine and corticosteroids to prevent organ rejection after hepatic, renal, and cardiac transplants. It is...
Approved
Investigational
Matched Description: … [L7363] It is marketed by Roche Pharmaceuticals and was granted FDA approval for the prophylaxis of transplant ... Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified ... to prevent organ rejection after hepatic, renal, and cardiac transplants. …
Matched Categories: … Mycophenolic Acid and Prodrugs …
Matched Products: … CELLCEPT FOR I.V. INFUSION 500 mg/vial ... Mycophenolate Mofetil for Injection USP ... Mycophenolate Mofetil for Injection, USP …

Clostridium tetani toxoid antigen (formaldehyde inactivated)

Clostridium tetani toxoid antigen (formaldehyde inactivated) is a vaccine for intramuscular injection. It is used for active immunization of children 7 years of age or older, and adults, for prevention of tetanus. The toxoid in the Clostridium tetani culture is grown and detoxified followed by purification via ammonium sulfate filtration...
Approved
Matched Description: … It is used for active immunization of children 7 years of age or older, and adults, for prevention of ... sulfate filtration and precipation. ... The toxoid in the Clostridium tetani culture is grown and detoxified followed by purification via ammonium …
Matched Mixtures name: … NIMENRIX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... Nimenrix Powder and Solvent for Solution for Injection ... Tetanus and Diphtheria Toxoids Adsorbed for Adult Use …
Matched Categories: … Antiinfectives for Systemic Use …
Matched Products: … TETAVAX single dose, suspension for injection in a prefilled syringe …

Rabies immune globulin, human

IMOGAM Rabies Pasteurized is indicated for post-exposure prophylaxis in persons suspected of exposure to rabies, who have not previously received a complete immunization regimen with a cell culture produced rabies vaccine. Persons previously vaccinated with other types of rabies vaccines in whom adequate antibody levels have not been demonstrated should...
Approved
Matched Description: … Recommendations for passive and/or active immunization after exposure to an animal suspected of having ... adequate antibody levels have not been demonstrated should receive full post-exposure prophylaxis with RIG and ... Advisory Committee on Immunization (NACI), the Advisory Committee on Immunization Practices (ACIP), and …
Matched Products: … HyperRAB Solution for Infiltration & Intramuscular Injection …

Dobutamine

A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.
Approved
Matched Categories: … Adrenergic and Dopaminergic Agents …
Matched Products: … Pharmaniaga Dobutamine 12.5mg/mL Concentrate for Solution for Infusion …

Strontium ranelate

Strontium ranelate, a strontium (II) salt of ranelic acid, is a medication for osteoporosis. Some reports have shown that strontium ranelate can slow down the progression of osteoarthritis of the knee. This agent presents an atypical mechanism of action in which it increases deposition of new bone by osteoblasts and,...
Approved
Withdrawn
Matched Description: … Strontium ranelate, a strontium (II) salt of ranelic acid, is a medication for osteoporosis. ... intrinsic bone tissue quality and microarchitecture in osteoporosis by way of a number of cellular and ... and various life threatening allergic reactions. …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization ... strontium ranelate and colecalciferol ... Drugs for Treatment of Bone Diseases …
Matched Products: … PROTOS Granules for Oral Suspension 2g …

(7R,12R,13R)-13-formyl-12,14-dihydroxy-3,5,7-trimethyltetradeca-2,4-dienoic acid

Experimental
Matched Name: … (7R,12R,13R)-13-formyl-12,14-dihydroxy-3,5,7-trimethyltetradeca-2,4-dienoic acid …
Matched Iupac: … (4E,7R,12R,13R)-13-formyl-12,14-dihydroxy-3,5,7-trimethyltetradeca-2,4-dienoic acid …

(2S,3S)-3-FORMYL-2-({[(4-METHYLPHENYL)SULFONYL]AMINO}METHYL)PENTANOIC ACID

Experimental
Matched Name: … (2S,3S)-3-FORMYL-2-({[(4-METHYLPHENYL)SULFONYL]AMINO}METHYL)PENTANOIC ACID …
Matched Iupac: … (2S,3S)-3-formyl-2-[(4-methylbenzenesulfonamido)methyl]pentanoic acid …

Idarubicin

An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Approved
Matched Description: … The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential ... for reduced cardiac toxicity. …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … ZAVEDOS FOR INJECTION 5 mg/vial ... ZAVEDOS FOR INJECTION 10 mg/vial …
Displaying drugs 1726 - 1750 of 1858 in total