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Displaying drugs 1926 - 1950 of 9325 in total
Sulfisoxazole acetyl is an ester of sulfisoxazole, a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial activity. Sulfisoxazole acetyl competes with PABA for the bacterial enzyme, dihydropteroate synthase, preventing the incorporation of PABA into dihydrofolic acid, which is the precursor of folic acid. This process causes...
Approved
Vet approved
Matched Iupac: … N-(4-aminobenzenesulfonyl)-N-(3,4-dimethyl-1,2-oxazol-5-yl)acetamide …
Cefiderocol is a cephalosporin antibacterial drug and exerts a mechanism of action similar to other β-lactam antibiotics.[FDA Label] Unlike other agents in this category, cefiderocol is a siderophore able to undergo active transport into the bacterial cell through iron channels. It represents a significant addition to antibacterial treatment option as...
Approved
Investigational
Matched Iupac: … -8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-{2-[(2-chloro-3,4-dihydroxyphenyl)formamido] ... 1-{[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido]-2-carboxylato ... ethyl}pyrrolidin-1-ium …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
A guanido-neuraminic acid that is used to inhibit neuraminidase.
Approved
Investigational
Matched Synonyms: … 5-acetamido-2,6-anhydro-3,4,5-trideoxy-4-guanidino-D-glycero-D-galacto-non-2-enonic acid ... (2R,3R,4S)-3-(acetylamino)-4-carbamimidamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran- ... 5-(acetylamino)-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-D-glycero-D-galacto-non-2-enonic acid …
Matched Iupac: … (2R,3R,4S)-4-[(diaminomethylidene)amino]-3-acetamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
A phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.
Approved
Matched Synonyms: … 2-(4-(3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl)-1-piperazinyl)ethanol ... 1-(2-hydroxyethyl)-4-(3-(trifluoromethyl-10-phenothiazinyl)propyl)-piperazine ... 4-(3-(2-trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol …
Matched Iupac: … 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol …
Matched Salts cas: … 5002-47-1 ... 2746-81-8
Matched Products: … Fluphenazine 2 Tab 2mg ... Fluphenazine 1 Tab 1mg ... PROLİXİN DECANOATE 25 MG/ML I.M UZATILMIŞ SALIMLI ENJEKSİYONLUK ÇÖZELTİ, 1 ADET …
Choline C 11 Injection is a radioactive diagnostic agent for positron emission tomography (PET) imaging of pat ients with suspected prostate cancer recurrence and non-informative bone scintigraphy, computerized tomography (CT) or magnetic resonance imaging.
Approved
Matched Iupac: … (2-hydroxyethyl)((11C)methyl)dimethylazanium …
A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients.
Approved
Investigational
Matched Synonyms: … 1,4-Dihydro-1-deoxy-1',4-didehydro-5'-(2-methylpropyl)-1-oxorifamycin XIV ... 4-Deoxo-3,4-(2-spiro(N-isobutyl-4-piperidyl)-2,5-dihydro-1H-imidazo)-rifamycin S …
Matched Iupac: … -(2-methylpropyl)-6,23,32-trioxo-8,33-dioxa-24,27,29-triazaspiro[pentacyclo[23.6.1.1^{4,7}.0^{5,31}.0 ... ^{26,30}]tritriacontane-28,4'-piperidin]-1(31),2,4,9,19,21,25,29-octaen-13-yl acetate ... 11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17-trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-1' …
Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and PARP2.[L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work by taking advantage of a defect in DNA repair in cancer cells with BRCA mutations and inducing cell death. Olaparib...
Approved
Matched Synonyms: … 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one …
Matched Iupac: … 4-{[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorophenyl]methyl}-1,2-dihydrophthalazin-1-one …
Matched Categories: … MATE 2-K Inhibitors ... MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring …
Estradiol is a naturally occurring hormone circulating endogenously in females. It is commercially available in several hormone therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and hot flashes. Some available forms of estradiol include oral tablets, injections, vaginal rings, transdermal patches, sprays, gels, and creams.[L11485,L11488,L11491,...
Approved
Investigational
Vet approved
Matched Mixtures name: … Angeliq 1 mg/2 mg Filmtabletten ... Parapanol kombi 2 mg/1 mg - Filmtabletten ... ANGELIQ 1 MG/2 MG FILM KAPLI TABLET, 28 ADET …
Matched Products: … VIPLEN 1 MG ... POSTMENOP 1 MG ... เอสโตรเฟม 1 มก. …
Iron deficiency anemia is a large public health concern worldwide, especially in young children, infants, and women of childbearing age. This type of anemia occurs when iron intake, iron stores, and iron loss do not adequately support the formation of erythrocytes, also known as red blood cells. Ferrous sulfate is...
Approved
Matched Synonyms: … iron(2+) sulfate (anhydrous) ... iron sulfate (1:1) …
Matched Iupac: … lambda2-iron(2+) sulfate …
Matched Mixtures name: … Revival 1 Tab …
Coumarin derivative that acts as a long-acting oral anticoagulant.
Approved
Investigational
Matched Synonyms: … 4-Hydroxy-3-(1-phenylpropyl)-2H-1-benzopyran-2-one ... 4-hydroxy-3-(1-phenylpropyl)-2H-chromen-2-one ... 3-(1-Phenylpropyl)-4-hydroxycoumarin …
Matched Iupac: … 4-hydroxy-3-(1-phenylpropyl)-2H-chromen-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Also known as Aspirin, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction...
Approved
Vet approved
Matched Synonyms: … 2-Acetoxybenzoic acid ... 2-Acetoxybenzenecarboxylic acid ... acide 2-(acétyloxy)benzoïque …
Matched Iupac: … 2-(acetyloxy)benzoic acid …
Matched Salts cas: … 62952-06-1
Matched Mixtures name: … Methoxisal-C 1/8 ... Robaxisal C-1/8 Tablets ... Fiorinal-C 1/2
Matched Categories: … Non COX-2 selective NSAIDS …
An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity. The drug is generally well tolerated.
Approved
Matched Synonyms: … 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone ... 2-(2'-hydroxy-3'-propylaminopropoxy)-ω-phenylpropiophenone …
Matched Iupac: … 1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria. It is generally given in combination with trimethoprim, which inhibits a sequential step in bacterial folic acid synthesis - these agents work synergistically to block two consecutive steps in the biosynthesis of nucleic acids and...
Approved
Matched Iupac: … 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzene-1-sulfonamide …
Matched Mixtures name: … CO-TRIPIRIM 5 ML 1 AMPUL ... ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL, 1 ADET …
The Moderna COVID-19 Vaccine (mRNA-1273) is a novel mRNA-based vaccine encapsulated in a lipid nanoparticle that encodes for a full-length pre-fusion stabilized spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Coronavirus disease 2019 (COVID-19) is a highly contagious infectious disease caused by the novel coronavirus, SARS-CoV-2, leading...
Approved
Investigational
Matched Synonyms: … MRNA-1273 SARS-COV-2
Matched Description: … (SARS-CoV-2). ... NCT04283461) was initiated in March 2020 in which 45 subjects received two intramuscular doses (on days 1 ... full-length pre-fusion stabilized spike (S) protein of severe acute respiratory syndrome coronavirus 2
Pipradrol (Meratran) was initially developed in the 1950s as an antidepressant, however, the adverse effects associated with its use and its abuse potential led to its withdrawal and international regulation . Pipradrol was made illegal in many countries in 1970s because of its potential for abuse. It is currently classified...
Approved
Matched Iupac: … diphenyl(piperidin-2-yl)methanol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Betibeglogene autotemcel is an autologous gene therapy that adds functional copies of the β-globin gene (βA-T87Q-globin) to hematopoietic stem cells in order to treat β-thalassemia. β-thalassemia is a condition caused by mutations in the β-globin gene (HBB) that leads to a significant decrease in the production of β-globin. This affects...
Approved
Investigational
Phenytoin is classified as a hydantoin derivative and despite its narrow therapeutic index, it is one of the most commonly used anticonvulsants.[A33595,A188832,A189219] Since it's introduction about 80 years ago, phenytoin has not only been established as an effective anti-epileptic, but has also been investigated for several other indications such as...
Approved
Vet approved
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … FENITOINA INYECTABLE 100 MG/ 2 ML …
Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis. First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular carcinoma, sorafenib is also...
Approved
Investigational
Matched Synonyms: … N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea ... 4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide …
Matched Iupac: … 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide …
Matched Salts cas: … 475207-59-1
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.[L8384,L8387,L8390] Lisinopril and captopril are the only ACEIs that are not prodrugs. It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system.[A184781,A184808,A184817] ACEIs are commonly used as a...
Approved
Investigational
Matched Synonyms: … (S)-1-(N(2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline ... [N2-[(S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline …
Matched Iupac: … (2S)-1-[(2S)-6-amino-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}hexanoyl]pyrrolidine-2-carboxylic acid …
Matched Products: … Lisinopril Taw Pharma 1 mg/ml Lösung zum Einnehmen …
Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Approved
Matched Mixtures name: … ENDOFALK TOZ İÇEREN SAŞE, 8 SAŞE ... Phoxilium 1,2 mmol/l Phosphat Hämodialyse-/Hämofiltrationslösung ... Prismasol 2
Matched Products: … BICARBONATO DE SODIO 1 MOLAR ... BICARBONATO DE SODIO 1 MEQ / ML ... Natriumbicarbonat "Fresenius" 1 molar - Infusionszusatz - Ampullen …
Dalteparin, a low molecular weight heparin (LMWH) prepared by nitrous acid degradation of unfractionated heparin of porcine intestinal mucosa origin, is an anticoagulant. It is composed of strongly acidic sulphated polysaccharide chains with an average molecular weight of 5000 and about 90% of the material within the range of 2000-9000....
Approved
Matched Products: … Fragmin 10.000 IE/1 ml - Ampullen …
Fospropofol is a water soluble prodrug and is converted to propofol in the liver. Fospropofol is a short acting hypnotic/sedative/anesthetic agent. Unlike propofol, does not cause injection-site pain as it is unable to activate TRPA1. FDA approved in December 2008. Fospropofol is a Schedule IV controlled substance in the United...
Approved
Illicit
Investigational
Matched Iupac: … {[2,6-bis(propan-2-yl)phenoxy]methoxy}phosphonic acid …
Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure.[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor...
Approved
Matched Synonyms: … (+-)-1-((alpha-(2-Isopropoxyethoxy)-p-tolyl)oxy)-3-(isopropylamino)-2-propanol ... (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol …
Matched Iupac: … 1-[(propan-2-yl)amino]-3-(4-{[2-(propan-2-yloxy)ethoxy]methyl}phenoxy)propan-2-ol …
Matched Salts cas: … 104344-23-2
Matched Categories: … Adrenergic beta-1 Receptor Antagonists …
Floctafenine is an anti-inflammatory analgesic similar in action to aspirin. Floctafenine inhibits prostaglandin synthesis.
Approved
Withdrawn
Matched Iupac: … 2,3-dihydroxypropyl 2-{[8-(trifluoromethyl)quinolin-4-yl]amino}benzoate …
Matched Categories: … Non COX-2 selective NSAIDS …
Displaying drugs 1926 - 1950 of 9325 in total