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Displaying drugs 1951 - 1975 of 1990 in total
Experimental
Matched Name: … 6-(4-{(1S,2S)-2-AMINO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}PHENYL
Matched Iupac: … -amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxo-2-(4-{[1,2,4]triazolo[1,5-a]pyridin-6-yl}phenyl
Experimental
Matched Name: … 2-(4-(2-((3-(5-(PYRIDIN-2-YLTHIO)THIAZOL-2-YL)UREIDO)METHYL)-1H-IMIDAZOL-4-YL)PHENOXY)ACETIC ACID …
Matched Iupac: … 2-(4-{2-[({[5-(pyridin-2-ylsulfanyl)-1,3-thiazol-2-yl]carbamoyl}amino)methyl]-1H-imidazol-4-yl}phenoxy
Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … It is essential for normal growth and development and helps to maintain proper functioning of the heart ... and the nervous and digestive systems. ... It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. …
Matched Mixtures name: … Multivitamins and Minerals for Men ... Multivitamins and Minerals for Women ... Luna Vitamin and Mineral Bar for Women …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … ALINAMIN FORTE
Etofenamate is used to treat muscle and joint paint. It is a non-steroidal anti-inflammatory drug (NSAID).
Experimental
Matched Iupac: … 2-(2-hydroxyethoxy)ethyl 2-{[3-(trifluoromethyl)phenyl]amino}benzoate …
Matched Description: … Etofenamate is used to treat muscle and joint paint. …
Matched Categories: … Topical Products for Joint and Muscular Pain ... Antiinflammatory Preparations, Non-Steroids for Topical Use …
Matched Products: … RHEUMON ® FORTE GEL …
Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. It is being investigated in cancers.[A257281,A257286]
Investigational
Matched Synonyms: … (3'r,4's,5'r)-4-((6-chloro-2-oxo-1,2-dihydro-spiro(indole-3,3'-pyrrolidin)e-4'-(3-chloro-2-fluoro -phenyl
Matched Description: … Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. …
Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such...
Approved
Matched Iupac: … (2S)-2-[(4-{[(4-amino-2-imino-2,3-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic …
Matched Description: … of some forms of arthritis and severe psoriasis only if first line treatment has failed or patients ... Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis ... inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acid Synthesis Inhibitors …
Matched Products: … Zexate® Solution for Injection or Infusion 25 mg/ml ... TREXOL - Methotrexate Solution for Injection 25 mg/ml ... TREXOL - Methotrexate Solution for Injection 100 mg/ml …
A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly...
Approved
Matched Description: … mainly for asthma, bronchospasm, and COPD. ... Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated ... methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and
Matched Mixtures name: … Theophylline 4mg and 5% Dextrose Inj ... Theophylline 1.6mg and 5% Dextrose Inj ... Theophylline 0.8mg and 5% Dextrose Inj …
Matched Categories: … Xanthines and Adrenergics ... theophylline and adrenergics ... Drugs for Obstructive Airway Diseases …
Matched Products: … AFPRED FORTE THEO 200MG ... BRONCHORETARD 500 FORTE
Experimental
Matched Name: … (2S,3S)-4-cyclopropyl-3-{(3R,5R)-3-[2-fluoro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazolidin-5-yl}-1-[( …
Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide. While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain, it exerts its antipsychotic effect through its strong antagonism of the dopamine receptor (mainly D2), particularly within...
Approved
Matched Description: … [F4645] It is also used off-label for the management of chorea associated with Huntington's disease and ... However, haloperidol use remains widespread and is considered the benchmark for comparison in trials ... Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently …
Matched Products: … HALOPIDOL FORTE GOTAS. ... HALOPERIDOL-NEURAX FORTE
Hydromorphone is a pure opioid, a semi-synthetic hydrogenated ketone derivative of morphine that has been available clinically since 1920. Structurally, hydromorphone derived from morphine in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and...
Approved
Illicit
Matched Description: … Hydromorphone is a pure opioid,[A176468] a semi-synthetic hydrogenated ketone derivative of [morphine ... the absence of a double bond between the carbon 7 and 8. ... hydrochloride was developed by Fresenius Kabi USA and FDA approved in 1984. …
Matched Categories: … hydromorphone and naloxone ... hydromorphone and antispasmodics ... Semi-synthetic Opioids …
Matched Products: … Hydromorphone Hp Forte Injection ... Hydromorphone Hydrochloride Injection Hp Forte
Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.[FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus.[A181802,T116] Ketoconazole was first approved in an oral formulation...
Approved
Investigational
Matched Iupac: … 1-[4-(4-{[2-(2,4-dichlorophenyl)-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin …
Matched Description: … [FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol ... [A181802,T116] Ketoconazole was first approved in an oral formulation for systemic use by the FDA in ... [clotrimazole], due to its broad spectrum and good absorption. …
Matched Categories: … Steroid Synthesis Inhibitors ... Sex Hormones and Insulins ... Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … FAZOL FORTE SHAMPOO ... FAZOL® FORTE HERBAL SHAMPOO …
Levothyroxine is a synthetically produced form of thyroxine, a major endogenous hormone secreted by the thyroid gland. Also known as L-thyroxine or the brand name product Synthroid, levothyroxine is used primarily to treat hypothyroidism, a condition where the thyroid gland is no longer able to produce sufficient quantities of the...
Approved
Matched Description: … produce sufficient quantities of the thyroid hormones T4 (tetraiodothyronine or thyroxine) and ... hypothyroidism begin to develop such as fatigue, increased heart rate, depression[A179620], dry skin and ... hair, muscle cramps, constipation, weight gain, memory impairment, and poor tolerance to cold temperatures …
Matched Mixtures name: … Combithyrex forte - Tabletten ... Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... levothyroxine sodium and iodine compounds ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Levothyroxine Sodium for Injection ... LEVOTHYROXINE SODIUM FOR INJECTION 500 mcg/vial …
Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to...
Approved
Investigational
Matched Description: … It is available in the oral tablet form or in solution, and can also be administered through the intravenous ... impact on quality of life and poses a significant burden on the healthcare system. ... Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative …
Matched Categories: … Alimentary Tract and Metabolism ... Benzamides and benzamide derivatives ... Drugs for Functional Gastrointestinal Disorders …
Matched Products: … Metoperan Solution for Injection 5mg/mL …
Epinephrine, also known as adrenaline, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been...
Approved
Vet approved
Matched Description: … Epinephrine, also known as _adrenaline_, is a hormone and neurotransmitter and produced by the adrenal ... , and subcutaneous injection. ... other allergens, and to prolong the action of infiltration anesthetics [F2136]. …
Matched Mixtures name: … Ultacan Forte ... Citanest Forte ... Lignospan Forte
Matched Categories: … epinephrine and other drugs for obstructive airway diseases ... Phenols ... Adrenergic and Dopaminergic Agents ... Epinephrine and similars ... Alpha-and Beta-adrenergic Agonists …
Matched Products: … ARTINIBSA 4% WITH EPINEPHRINE SOLUTION FOR INJECTION 1:100000 …
Travoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective FP prostanoid receptor agonist. It is used to decrease intraocular pressure in open-angle glaucoma and ocular hypertension. Unlike other prostaglandin analogues, travoprost demonstrates full agonism and high selectivity at the prostanoid receptor, reporting a higher...
Approved
Matched Synonyms: … .))-7-(3,5-DIHYDROXY-2-(3-HYDROXY-4-(3-(TRIFLUOROMETHYL)PHENOXY)-1-BUTENYL)CYCLOPENTYL)-5-HEPTENOIC ACID …
Matched Iupac: … propan-2-yl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but …
Matched Description: … Travoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective ... risk for developing off-target side effects. ... It is used to decrease intraocular pressure in open-angle glaucoma and ocular hypertension. …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Prostaglandins, Synthetic ... Prostaglandins F, Synthetic
Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Description: … [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the ... [L39429] Baclofen was investigated for use in alcohol dependence and withdrawal; however, evidence ... used to manage severe muscle spasms of cerebral or spinal cord origins, including multiple sclerosis and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … OREN FORTE TABLETAS …
Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including the brain and cerebrospinal fluid, into interstitial fluid and plasma. As a...
Approved
Investigational
Matched Description: … pulmonary symptoms associated with cystic fibrosis in adult patients and is currently marketed for this ... or sugar alcohol, in fruits and vegetables. ... As a result, cerebral edema, elevated intracranial pressure, and cerebrospinal fluid volume and pressure …
Matched Mixtures name: … INFUSOL M20S (Mannitol 17.5%w/v and Sorbitol 2.5%w/v Intravenous Infusion) ... TERUFLEX Blood Bag System with Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND ... (Saving Platelets) with Diversion Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) and
Matched Categories: … Drugs for Constipation ... Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Diet, Food, and Nutrition ... Cough and Cold Preparations …
Matched Products: … Braun Mannitol 20% Solution for Infusion …
Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs...
Approved
Matched Description: … phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and ... angina,[L8791] and was the first calcium channel antagonist to be introduced into therapy in the early ... of the non-dihydropyridine class of calcium channel blockers, which includes drugs like [diltiazem] and
Matched Mixtures name: … TARKA FORTE 240/4 FILM TABLET, 28 ADET ... VERAPIN FORTE 240MG/4MG FILM TABLET,28 ADET ... Trandolapril and Verapamil Hydrochloride …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Verapamil and analogues ... trandolapril and verapamil ... Antihypertensive Agents Indicated for Hypertension …
Matched Products: … Isocor 2.5 mg/mL solution for injection or infusion …
Butylscopolamine is a peripherally acting antimuscarinic, anticholinergic agent. It is used to treat pain and discomfort caused by abdominal cramps, menstrual cramps, or other spasmodic activity in the digestive system. It is also effective at preventing bladder spasms. It is not a pain medication in the normal sense, since it...
Approved
Investigational
Vet approved
Matched Description: … It is used to treat pain and discomfort caused by abdominal cramps, menstrual cramps, or other spasmodic ... the normal sense, since it does not directly affect pain, but rather works to prevent painful cramps and
Matched Mixtures name: … COLFEM FORTE TABLETAS ... LABINPINA FORTE 10/500 MG TABLETAS CUBIERTAS ( HIOSCINA N- BUTILBROMURO + ACETAMINOFEN ) …
Matched Categories: … Alimentary Tract and Metabolism ... Belladonna and Derivatives, Plain ... butylscopolamine and analgesics ... Drugs for Functional Gastrointestinal Disorders …
Matched Products: … Fucon Solution for Injection 20mg/ml …
Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the...
Approved
Investigational
Matched Description: … It stimulates synthesis and release of surfactant by type II pneumocytes. ... in providing protection against infection and irritating agents. ... The substance is a mucoactive drug with several properties including secretolytic and secretomotoric …
Matched Categories: … Cough and Cold Preparations ... clenbuterol and ambroxol ... Adrenergics for Systemic Use ... Drugs for Obstructive Airway Diseases …
Matched Products: … MUCERA FORTE ... SILOPECT FORTE
Experimental
Matched Name: … 2-[(S)-amino(hydroxy)methoxy]-2,3-dihydro-1H-inden-1-yl}-2-benzyl-3-oxo-2-pyrrolidinyl]-3-hydroxy-1-phenyl
Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength...
Approved
Investigational
Matched Description: … [A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk ... strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine], and ... [A176050] Morphine is still routinely used today, though there are a number of semi-synthetic opioids …
Matched Categories: … morphine and antispasmodics …
Matched Products: … Morphine Forte ... Morphine Extra-forte
Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool.[A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional medicine dates back more than a hundred years.[A256267,A256463] UDCA was first characterized...
Approved
Investigational
Matched Description: … [A256272] UDCA was first approved by the FDA in 1987 for dissolution of gallstones and for primary ... [A256267,A256463] UDCA was first characterized in the bile of the Chinese black bear and is formed by ... [A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional …
Matched Categories: … Alimentary Tract and Metabolism ... Bile Acids and Salts ... Bile acids and derivatives ... Bile and Liver Therapy ... Cholagogues and Choleretics …
Matched Products: … Urso Forte
Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints . This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals . Allopurinol is a xanthine oxidase enzyme inhibitor that...
Approved
Matched Description: … This disease has been well-documented in historical medical records and appears in the biographies of ... It was initially approved by the FDA in 1966 [L5674] and is now formulated by several manufacturers [ ... enzyme inhibitor that is considered to be one of the most effective drugs used to decrease urate levels and
Matched Products: … MEDIURIC FORTE
Estradiol is a naturally occurring hormone circulating endogenously in females. It is commercially available in several hormone therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and hot flashes. Some available forms of estradiol include oral tablets, injections, vaginal rings, transdermal patches, sprays, gels, and creams.[L11485,L11488,L11491,...
Approved
Investigational
Vet approved
Matched Description: … [DB00977] (EE) is a synthetic form of estradiol commonly used as the estrogenic component of most combination ... , sprays, gels, and creams. ... reduced estrogen, such as vulvovaginal atrophy and hot flashes. …
Matched Mixtures name: … Estradiol and Norethindrone Acetate ... Estradiol and Norethindrone Acetate ... Estradiol and Norethindrone Acetate …
Matched Categories: … Hormonal Contraceptives for Systemic Use ... Androgens and Estrogens ... Antiandrogens and Estrogens ... Pituitary and Hypothalamic Hormones and Analogues ... etynodiol and estrogen …
Matched Products: … CLIMARA FORTE 7.8 MG/25 CM2 TRANSDERMAL FLASTER, 4 ADET …
Displaying drugs 1951 - 1975 of 1990 in total