Displaying drugs 1951 - 1975 of 15241 in total
Bos taurus hair
Bos taurus hair is used in allergenic testing.
Approved
Matched Mixtures name: … Cattle Hair and Epithelia ... Animal Allergens, AP Cattle Hair and Dander ... Animal Allergens, AP Cattle Hair and Dander …
Opicapone
Opicapone is a potent, reversible, and peripherally-acting third-generation inhibitor of catechol-o-methyltransferase (COMT), an enzyme involved in the breakdown of various catecholamines including dopamine.[A36938, A203048] Many patients with Parkinson’s disease treated with levodopa plus a dopa decarboxylase (DDC) inhibitor (eg carbidopa) experience motor complications over time, which calls for the management...
Approved
Investigational
Matched Description: … disease and end-of-dose motor fluctuations. ... Opicapone is a potent, reversible, and peripherally-acting third-generation inhibitor of catechol-o-methyltransferase ... Opicapone was approved for use by the European Commission in June 2016 [L2339] and the FDA in April 2020 …
Oxandrolone
A synthetic hormone with anabolic and androgenic properties.
Approved
Investigational
Matched Description: … A synthetic hormone with anabolic and androgenic properties. …
Matched Categories: … Alimentary Tract and Metabolism ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Alimentary Tract and Metabolism ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Polydatin
Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline structure. While it is isolated from the bark of Picea sitchensis or Polygonum cuspidatum, polydatin may be detected in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products and many daily diets...
Approved
Matched Description: … Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline ... Polydatin possesses anti-inflammatory, immunoregulatory, anti-oxidative and anti-tumor activities. ... in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products and …
Troleandomycin
A macrolide antibiotic that is similar to erythromycin.
Approved
Matched Categories: … Macrolides, Lincosamides and Streptogramins …
Escitalopram
Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic citalopram. It is used to restore serotonergic function in the treatment of depression and anxiety.[L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and is responsible for the vast majority of citalopram’s clinical activity, with...
Approved
Matched Description: … [A185420] It is used to restore serotonergic function in the treatment of depression and anxiety. ... Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic [citalopram ... L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and …
Grazoprevir
Grazoprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Matched Description: … Subtitutions at amino acid positions 155, 156, or 168 are known to confer resistance. ... with or without [DB00811] depending on the the presence of resistance associated amino acid substitutions ... to achieve a SVR between 94% and 97% for genotype 1 and 97% and 100% for genotype 4 after 12 weeks of …
Matched Categories: … elbasvir and grazoprevir …
Matched Categories: … elbasvir and grazoprevir …
Agrostis gigantea pollen
Agrostis gigantea pollen is the pollen of the Agrostis gigantea plant. Agrostis gigantea pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … K-O-R-T and Sweet Vernal Standardized Grass Pollen Mix ... K-O-R-T and Sweet Vernal Standardized Grass Pollen Mix ... Mixture of Standardized and Non-Standardized Inland Grasses …
Levothyroxine
Levothyroxine is a synthetically produced form of thyroxine, a major endogenous hormone secreted by the thyroid gland. Also known as L-thyroxine or the brand name product Synthroid, levothyroxine is used primarily to treat hypothyroidism, a condition where the thyroid gland is no longer able to produce sufficient quantities of the...
Approved
Matched Iupac: … (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid …
Matched Description: … produce sufficient quantities of the thyroid hormones T4 (tetraiodothyronine or thyroxine) and ... hypothyroidism begin to develop such as fatigue, increased heart rate, depression[A179620], dry skin and ... [F4633] T4 and T3 act on nearly every cell of the body, but have a particularly …
Matched Mixtures name: … Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid …
Matched Categories: … Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... levothyroxine sodium and iodine compounds ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … produce sufficient quantities of the thyroid hormones T4 (tetraiodothyronine or thyroxine) and ... hypothyroidism begin to develop such as fatigue, increased heart rate, depression[A179620], dry skin and ... [F4633] T4 and T3 act on nearly every cell of the body, but have a particularly …
Matched Mixtures name: … Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid …
Matched Categories: … Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... levothyroxine sodium and iodine compounds ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Zonisamide
Zonisamide is a sulfonamide anticonvulsant used as an adjunctive therapy in adults with partial-onset seizures.[L42530,L42535] Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels, leading to a reduction of T-type calcium channel currents or by binding allosterically to GABA receptors. This latter action may inhibit the uptake of...
Approved
Investigational
Matched Description: … The US and Europe approved it in 2000 and 2005, respectively.[A1379,A1383] …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Prazosin
Prazosin is a drug used to treat hypertension. Prazosin is marketed by Pfizer and was initially approved by the FDA in 1988. It belongs to the class of drugs known as alpha-1 antagonists.
Recently, many studies have evaluated the benefits of this drug in controlling the symptoms of post-traumatic stress...
Approved
Matched Description: … Prazosin is marketed by _Pfizer_ and was initially approved by the FDA in 1988. ... evaluated the benefits of this drug in controlling the symptoms of post-traumatic stress disorder (PTSD) and …
Matched Categories: … prazosin and diuretics ... Alpha-Adrenoreceptor Antagonists and Diuretics …
Matched Categories: … prazosin and diuretics ... Alpha-Adrenoreceptor Antagonists and Diuretics …
Resorcinol
Resorcinol is a 1,3-isomer (or meta-isomer) of benzenediol with the formula C6H4(OH)2. It is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin disorders and infections such as acne, seborrheic dermatitis, eczema, psoriasis, corns, calluses, and warts. It exerts a keratolytic activity. Resorcinol works...
Approved
Matched Description: … disorders and infections such as acne, seborrheic dermatitis, eczema, psoriasis, corns, calluses, and ... It is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin …
Matched Mixtures name: … BENZOCAINE and RESORCINOL ... BENZOCAINE and RESORCINOL ... BENZOCAINE and RESORCINOL …
Matched Mixtures name: … BENZOCAINE and RESORCINOL ... BENZOCAINE and RESORCINOL ... BENZOCAINE and RESORCINOL …
Voclosporin
Lupus nephritis (LN) is a type of glomerulonephritis occurring in patients with systemic lupus erythematosus (SLE). LN is a significant cause of renal failure, morbidity, and death in patients with SLE. Within 10 years of being diagnosed with SLE, 5-20% of those suffering from LN develop end-stage kidney disease, a...
Approved
Investigational
Matched Description: … Early and accurate intervention for LN is important in improving clinical outcomes. ... LN is a significant cause of renal failure, morbidity, and death in patients with SLE. ... [L31208] Voclosporin has demonstrated a more stable pharmacokinetic and pharmacodynamic relationship …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Dactylis glomerata pollen
Dactylis glomerata pollen is the pollen of the Dactylis glomerata plant. Dactylis glomerata pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … K-O-R-T and Sweet Vernal Standardized Grass Pollen Mix ... K-O-R-T and Sweet Vernal Standardized Grass Pollen Mix ... Mixture of Standardized and Non-Standardized Inland Grasses …
Voxilaprevir
Voxilaprevir is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Description: … mature virus: NS3, NS4A, NS4B, NS5A, and NS5B [A19643]. ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and ... genetic material into the following structural and nonstructural proteins required for assembly into …
Matched Categories: … Amino Acids, Peptides, and Proteins ... sofosbuvir, velpatasvir and voxilaprevir …
Matched Categories: … Amino Acids, Peptides, and Proteins ... sofosbuvir, velpatasvir and voxilaprevir …
Atogepant
Atogepant is an oral antagonist of calcitonin gene-related peptide (CGRP) receptors indicated for the prevention of episodic migraine headaches. It was developed by AbbVie and received FDA approval under the brand name Qulipta in September 2021. While its approval was predated by two other members of the same drug family,...
Approved
Investigational
Matched Description: … [valproic acid] or [topiramate]) or beta-blockers (e.g. ... It was developed by AbbVie and received FDA approval under the brand name Qulipta in September 2021. ... ] While its approval was predated by two other members of the same drug family, namely [ubrogepant] and …
Pilocarpine
A naturally occurring alkaloid derived from the Pilocarpus plants, pilocarpine is a muscarinic acetylcholine agonist.[A262016, A262036] Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors. Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated intraocular pressure and glaucoma. The usage of glaucoma by...
Approved
Investigational
Matched Description: … intraocular pressure and glaucoma. ... [A262036] Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Anastrozole
Anastrozole is a non-steroidal aromatase inhibitor (AI), similar to letrozole, used to decrease circulating estrogen levels in the treatment of postmenopausal women with estrogen-responsive breast cancer. Anastrozole is also related to exemestane, a steroidal AI, but its non-steroidal nature provides stark advantages including a lack of steroid-associated adverse effects such...
Approved
Investigational
Matched Description: … provides stark advantages including a lack of steroid-associated adverse effects such as weight gain and ... drugs of choice in the treatment of postmenopausal breast cancer due to a more favourable efficacy and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Colfosceril palmitate
Colfosceril palmitate is a synthetic pulmonary surfactant administered in infants with respiratory distress syndrome. It was part of the first generation of commercially available artificial surfactants. It was developed by Burroughs Wellcome and it was FDA approved on August 6, 1990. Nowadays colfosceril palmitate is under the state of canceled...
Approved
Investigational
Withdrawn
Matched Description: … [T70] It was developed by Burroughs Wellcome and it was FDA approved on August 6, 1990. …
DL-dimyristoylphosphatidylcholine
A synthetic phospholipid used in liposomes and lipid bilayers for the study of biological membranes. It is used in commercial drug preparations to solubilize drugs for injection
Approved
Matched Description: … A synthetic phospholipid used in liposomes and lipid bilayers for the study of biological membranes. …
Matched Categories: … Indicators and Reagents …
Matched Categories: … Indicators and Reagents …
Doxazosin
Doxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms and hypertension. Other members of this drug class include Prazosin, Terazosin, Tamsulosin, and Alfuzosin. Because of its long-lasting effects, doxazosin can be administered once a day. It is marketed by Pfizer and was initially approved...
Approved
Matched Description: … [A180649] It is marketed by Pfizer and was initially approved by the FDA in 1990.[L7285] ... Other members of this drug class include [Prazosin], [Terazosin], [Tamsulosin], and [Alfuzosin]. ... Doxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms and …
Matched Mixtures name: … Cardura-1,2,and 4 ... Cardura-1,2,and 4 ... Cardura-1,2,and 4 …
Matched Categories: … doxazosin and finasteride ... Genito Urinary System and Sex Hormones …
Matched Mixtures name: … Cardura-1,2,and 4 ... Cardura-1,2,and 4 ... Cardura-1,2,and 4 …
Matched Categories: … doxazosin and finasteride ... Genito Urinary System and Sex Hormones …
Benzhydrocodone
Benzhydrocodone is a benzylic prodrug of hydrocodone. It was developed in an effort to reduce parenteral bioavailability of the active metabolite as a deterrent to abuse. Benzhydrocodone is indicated for use in the short-term management of pain. It was first approved by the FDA in February 2018 in combination with...
Approved
Matched Description: … February 2018 in combination with [acetaminophen] under the trade name Apadaz, marketed by KVK Tech and …
Matched Mixtures name: … Benzhydrocodone and Acetaminophen ... Benzhydrocodone and Acetaminophen ... Benzhydrocodone and Acetaminophen …
Matched Mixtures name: … Benzhydrocodone and Acetaminophen ... Benzhydrocodone and Acetaminophen ... Benzhydrocodone and Acetaminophen …
Fosphenytoin
Fosphenytoin is a water-soluble phenytoin prodrug used only in hospitals for the treatment of epileptic seizures. It works by slowing down impulses in the brain that cause seizures. Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials.
Approved
Investigational
Matched Iupac: … [(2,5-dioxo-4,4-diphenylimidazolidin-1-yl)methoxy]phosphonic acid …
Matched Description: … channels, and therefore limit repetitive firing of action potentials. ... Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium …
Matched Categories: … Phenytoin and Prodrugs …
Matched Description: … channels, and therefore limit repetitive firing of action potentials. ... Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium …
Matched Categories: … Phenytoin and Prodrugs …
Piretanide
Piretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine residues in an aromatic nucleus in the presence of other aromatically bonded functional groups.
Approved
Matched Iupac: … 4-phenoxy-3-(pyrrolidin-1-yl)-5-sulfamoylbenzoic acid …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Displaying drugs 1951 - 1975 of 15241 in total