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Displaying drugs 176 - 200 of 9336 in total

Elivaldogene autotemcel

Elivaldogene autotemcel is a gene therapy consisting of genetically modified autologous cells. It is used to provide functional copies of human adrenoleukodystrophy protein (ALDP) in patients with adrenoleukodystrophy, an X-linked genetic disorder characterized by missing or non-functional ABCD1 gene that codes for ALDP. ALDP is a key protein that normally...
Approved

Blinatumomab

Blinatumomab is a BiTE-class (bi-specific T-cell engager) constructed monoclonal antibody formed by the recombinant fusion of an anti-CD3 single-chain variable fragment (scFV) and an anti-CD19 scFV through a short peptide linker.[A254836,L44311] CD3 is an antigen expressed on the surface of T-cells, while CD19 is mostly expressed on the surface of...
Approved
Investigational
Matched Products: … BLİNCYTO 38,5 MCG İNFÜZYONLUK ÇÖZELTİ İÇİN KONSANTRE TOZ VE ÇÖZELTİ, 1 ADET …

Technetium Tc-99m tilmanocept

Technetium Tc-99m tilmanocept is a radiopharmaceutical diagnostic imaging agent approved by the U.S. Food and Drug Administration (FDA) for the imaging of lymph nodes with or without scintigraphic imaging. It is a macromolecule consisting of multiple units of diethylenetriaminepentaacetic acid (DTPA) and mannose, each covalently attached to a 10 kDa...
Approved
Investigational

Lolium perenne pollen

Lolium perenne pollen is the pollen of the Lolium perenne plant. Lolium perenne pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 9 Southern Grass Mix ... 9 Southern Grass Pollen Mix …

Levothyroxine

Levothyroxine is a synthetically produced form of thyroxine, a major endogenous hormone secreted by the thyroid gland. Also known as L-thyroxine or the brand name product Synthroid, levothyroxine is used primarily to treat hypothyroidism, a condition where the thyroid gland is no longer able to produce sufficient quantities of the...
Approved
Matched Iupac: … (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid …
Matched Description: … 14:1 ratio of secretion by the human thyroid gland. ... Desiccated thyroid products contain a ratio of T4 to T3 of 4.2:1, which is significantly lower than the ... physiological effects of the thyroid hormones; T4 and T3 have a relative potency of ~1: …
Matched Mixtures name: … Np Thyroid 60 ... NP Thyroid 60 ... NP Thyroid 60 …

Epinastine

Epinastine is used for the prevention of itching associated with allergic conjunctivitis. It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and H2-receptors to...
Approved
Investigational
Matched Iupac: … 2,4-diazatetracyclo[12.4.0.0^{2,6}.0^{7,12}]octadeca-1(18),3,7,9,11,14,16-heptaen-3-amine …
Matched Description: … It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells ... by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Hydroxyurea

Hydroxyurea is a non-alkylating antineoplastic agent that was first synthesized in 1869 but was not characterized biologically until 1928. It was first approved by the FDA in 1998 for the treatment of sickle cell anemia in adults. Although clinical evidence on the efficacy of hydroxyurea in certain conditions exists, hydroxyurea...
Approved

Tositumomab

Murine IgG2a lambda monoclonal antibody against CD20 antigen (2 heavy chains of 451 residues, 2 lambda chains of 220 residues). It is produced in an antibiotic-free culture of mammalian cells. It can be covalently linked to Iodine 131 (a radioactive isotope of iodine).
Approved
Investigational
Matched Description: … Murine IgG2a lambda monoclonal antibody against CD20 antigen (2 heavy chains of 451 residues, 2 lambda …

Dasiglucagon

Dasiglucagon is a glucagon analog that acts to increase blood sugar levels. It consists of 29 amino acids similar to endogenous glucagon; however, it contains seven substituted amino acids for improved physical and chemical stability in its drug formulation. In March 2021, the FDA approved dasiglucagon to treat severe hypoglycemia...
Approved
Investigational
Matched Description: … annually, about 7% to 25% of patients with type 2 diabetes mellitus treated with insulin experience ... Although it tends to be more common in type 1 diabetes mellitus, occurring in about 22% to 46% of patients …

Timolol

Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes. It is also used in tablet form as a drug to treat hypertension. Timolol was first approved by the FDA in 1978. This drug is marketed by several manufacturers...
Approved
Matched Synonyms: … (S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol …
Matched Iupac: … (2S)-1-(tert-butylamino)-3-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}propan-2-ol …
Matched Salts cas: … 91524-16-2 …
Matched Mixtures name: … XOLATIM %2+ %0,5 GÖZ DAMLASI, ÇÖZELTİ ,5 ML,1 ŞİŞE ... COSOPT PF OFTALMIK COZELTI, 60 ADET ... COSOPT PF OFTALMIK COZELTI, 60 ADET …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … TİMOCOPT %0,5 GÖZ DAMLASI, ÇÖZELTİ, 60 FLAKON …

Panobinostat

Panobinostat is an oral deacetylace (DAC) inhibitor approved on February 23, 2015 by the FDA for the treatment of multiple myeloma. The approval was accelerated based on progression-free survival, therefore confirmatory trials by the sponsor to demonstrate clinical efficacy in multiple myeloma treatment are in progress of being conducted. Panobinostat...
Approved
Investigational
Matched Synonyms: … 2-PROPENAMIDE, N-HYDROXY-3-(4-(((2-(2-METHYL-1H-INDOL-3-YL)ETHYL)AMINO)METHYL)PHENYL)-, (2E)- ... (2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]acrylamide …
Matched Iupac: … (2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Butabarbital

Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other barbiturates.[A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative anxiety.[A201977,L13613] Butabarbital is less commonly used in recent years, as more patients are typically prescribed benzodiazepines. Its short duration of action...
Approved
Illicit
Matched International brands: … Sarisol No. 2 …
Matched Synonyms: … 5-ethyl-5-(1-methylpropyl)barbituric acid ... 5-ethyl-5-(1-methylpropyl)-2,4,6(1H,3H,5H)-pyrimidinetrione …
Matched Iupac: … 5-(butan-2-yl)-5-ethyl-1,3-diazinane-2,4,6-trione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Calcium levulinate

The relatively new calcium levulinate is produced from a direct reaction between L- or levulinic acid levulose and calcium hydroxide . The resultant calcium levulinate formulation, when used as a calcium supplement, possesses a high calcium content that is observed to be 14.8% higher than the content typically found in...
Approved
Experimental

Festuca pratensis pollen

Festuca pratensis pollen is the pollen of the Festuca pratensis plant. Festuca pratensis pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 9 Southern Grass Mix ... 9 Southern Grass Pollen Mix …

Pinaverium

Pinaverium is a spasmolytic agent used for functional gastrointestinal disorders. It is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel function. It is shown to relieve GI spasm and pain, transit disturbances and other symptoms related to motility disorders and may be considered...
Approved
Matched Iupac: … 4-[(2-bromo-4,5-dimethoxyphenyl)methyl]-4-[2-(2-{6,6-dimethylbicyclo[3.1.1]heptan-2-yl}ethoxy)ethyl]morpholin …
Matched Description: … Although it is not a currently approved drug by the FDA, pinaverium is available in over 60 countries …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Pancrelipase

Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands. The pancrelipase mixture was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved on April 12, 2010. For further information on the components of this mixture...
Approved
Investigational
Matched Mixtures name: … MULTANZIM 60 DRAJE ... PANKREOFLAT 60 DRAJE ... PANKREOFLAT 170/310 MG FİLM TABLET, 60 ADET …

Glucosamine

Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation. Treatment with chondroprotective drugs, such as glucosamine sulfate may offer additional benefits to nonsteroidal anti-inflammatory drugs treating the painful symptoms of OA. Glucosamine is commonly used over the counter as...
Approved
Investigational
Matched Synonyms: … 2-amino-2-deoxy-D-glucose …
Matched Salts cas: … 66-84-2 …
Matched Mixtures name: … DONA PLUS 750 MG + 600 MG SAŞE, 60 ADET ... flexijoint 3-in-1 Joint Care Powder ... OSTEOACTIV 3-in-1 Joint Formula Powder …
Matched Products: … DONA 750 MG FİLM KAPLI TABLET, 60 ADET …

Insulin human

Human Insulin, also known as Regular Insulin, is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Human insulin is produced by recombinant DNA technology and is identical to endogenously produced insulin. Typically prescribed for the management of diabetes mellitus,...
Approved
Investigational
Matched Description: … and Type 2 Diabetes. ... Insulin is also used in the treatment of Type 2 Diabetes (T2D), another form of diabetes mellitus that ... Regular Insulin, is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 …
Matched Mixtures name: … MIXTARD 30 HM 100 IU/ML ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADET ... MIXTARD 30 HM 100 IU/ML ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADET ... Humulin 40/60 Inj …
Matched Products: … HUMULIN R 100 IU/ML ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... HUMULIN N (NPH) 100 IU/ML SÜSPANSİYON İÇEREN FLAKON, 1 ADET ... ACTRAPID HM 100 IU/ML ENJEKSİYONLUK ÇÖZELTI İÇEREN FLAKON, 1 ADET …

Lusutrombopag

Lusutrombopag is an orally bioavailable thrombopoietin receptor (TPOR) agonist developed by Shionogi & Company (Osaka, Japan). TPOR is a regulatory target site for endogenous thrombopoietin, which acts as a primary cytokine to promote megakaryocyte proliferation and differentiation, and affect other hematopoietic lineages as well, including erythroid, granulocytic and lymphoid lineages...
Approved
Investigational
Matched Iupac: … (2E)-3-{2,6-dichloro-4-[(4-{3-[(1S)-1-(hexyloxy)ethyl]-2-methoxyphenyl}-1,3-thiazol-2-yl)carbamoyl]phenyl ... }-2-methylprop-2-enoic acid …
Matched Description: … thrombocytopenia who were undergoing an invasive procedure with a platelet count less than 50 x 10^9/ …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Technetium Tc-99m etidronate

Approved
Matched Iupac: … (1-hydroxy-1-phosphonoethyl)phosphonic acid (99Tc)technetium …

Agrostis gigantea pollen

Agrostis gigantea pollen is the pollen of the Agrostis gigantea plant. Agrostis gigantea pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 9 Southern Grass Mix ... 9 Southern Grass Pollen Mix …

Brilliant blue G

Brilliant Blue G is used in an ophthalmic solution for staining the internal limiting membrane (ILM) of the eye during ophthalmic procedures.[A188841,A188844] This membrane is thin and translucent, making it difficult to identify during eye surgeries that require high levels of visual accuracy. Brilliant blue G, like its name, imparts...
Approved
Matched Iupac: … methylcyclohexa-2,5-dien-1-ylidene]methyl)-3-methylphenyl](ethyl)amino}methyl)benzene-1-sulfonate ... sodium 3-({[4-({4-[(4-ethoxyphenyl)amino]phenyl}[(1E,4E)-4-{ethyl[(3-sulfonatophenyl)methyl]iminiumyl}-2- …

Gemtuzumab ozogamicin

Gemtuzumab ozogamicin is a recombinant humanized IgG4 kappa antibody which is conjugated with calicheamicin derivative, a cytotoxic antitumor antibiotic isolated from fermentation of Micromonospora echinospora ssp. calichensis. Gemtuzumab ozogamicin has approximately 50% of the antibody loaded with 4-6 moles calicheamicin per mole of antibody [FDA Label]. The antibody is specifically...
Approved
Investigational
Matched Description: … on May 17, 2000 by FDA as a treatment for patients with CD33-positive AML in first relapse who are 60 ... On September 1 2017, gemtuzumab ozogamicin was again approved for the treatment of adults with newly ... It is also indicated for the treatment of patients aged 2 years and older with CD33-positive AML who …
Matched Products: … MYLOTARG 5 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 1 FLAKON …

Oleic Acid

An unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. (Stedman, 26th ed)
Approved
Investigational
Vet approved
Matched Iupac: … (9E)-octadec-9-enoic acid …
Matched Salts cas: … 143-19-1 …

Gallium citrate Ga-67

Gallium citrate Ga 67 is the citrate salt of the radioisotope gallium Ga 67. Although the mechanism is unknown, gallium Ga 67 concentrates in lysosomes and is bound to a soluble intracellular protein in certain viable primary and metastatic tumors and focal sites of inflammation, allowing scintigraphic localization. Ga-67 scintigraphy...
Approved
Matched Iupac: … (67Ga)gallium(3+) 2-hydroxypropane-1,2,3-tricarboxylate …
Matched Products: … GA - 67 MM-1 ... MON.GALYUM-67 74 MBQ/ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET (5 ML) ... MON.GALYUM-67 74 MBQ/ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET (2.5 ML) …
Displaying drugs 176 - 200 of 9336 in total