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Displaying drugs 176 - 200 of 14844 in total

Nafcillin

A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic drug. It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections caused by strains that are resistant to other penicillins, except those caused by MRSA. It may be used as a first-line therapy in...
Approved
Investigational
Matched Description: … It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections …
Matched Categories: … combinations of penicillins …

Pentoxifylline

Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties.[A226415, L30300] Although originally developed to treat intermittent claudication, a form of exertion-induced leg pain common in patients with peripheral arterial disease, PTX has been investigated for its possible...
Approved
Investigational
Matched Description: … blood and also has both anti-oxidant and anti-inflammatory properties. ... Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of ... treatment for COVID-19-induced pulmonary complications due to its ability to regulate the production of …
Matched Categories: … combinations of xanthines …
Matched Products: … PENTOX SR 400 MG KAPSUL, 20 ADET ... HEMOPENE RETARD 600 MGTABLET, 20 ADET ... İSKEMOKS 400 MG SR MİKROPELLET KAPSÜL, 20 KAPSÜL …

Quinidine

Quinidine is a D-isomer of quinine present in the bark of the Cinchona tree and similar plant species. This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.[A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute...
Approved
Investigational
Matched Description: … Quinidine is a D-isomer of [quinine] present in the bark of the Cinchona tree and similar plant species ... [A38016] Due to its side effects and increased risk of mortality, the use of quinidine was reduced over ... However, it continues to be used in the treatment of Brugada syndrome, short QT syndrome and idiopathic …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Quinine and stereoisomer …
Matched Products: … QUINICARDINE 200 MG KOMPRIME, 20 ADET …

Trolamine salicylate

Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid. It is a topical analgesic used for temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and bruises. Unlike other topical analgesics, trolamine...
Approved
Matched Description: … , muscle strains, sprains, and bruises. ... mild to moderate muscular and joint pains. ... Triethanolamine neutralizes the acidity of the salicylic acid. …
Matched Categories: … Anti-Inflammatory Agents, Non-Steroidal (Non-Selective) ... Non COX-2 selective NSAIDS ... Anti-Inflammatory Agents, Non-Steroidal …
Matched Products: … Up and Up Pain Relief Odorless ... Up and Up Odor-free Pain Relieving Cream …

Burosumab

Burosumab (KRN23) is an entirely human monoclonal IgG1 antibody that binds excess fibroblast growth factor 23 (FGF23) and has been successfully tested in clinical trials in children with X-linked hypophosphatemic rickets . The U.S. Food and Drug Administration approved Crysvita (burosumab) in April 2018. This is the first drug approved...
Approved
Investigational
Matched Description: … (XLH), which is a rare, inherited form of rickets. ... X-linked hypophosphatemia causes low circulating levels of phosphorus in the blood. ... It causes impaired bone growth and development in children and adolescents and issues with bone mineralization …
Matched Categories: … Drugs for Treatment of Bone Diseases ... Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … CRYSVITA® SOLUCIÓN PARA INYECCIÓN 20 MG/ML ... CRYSVITA® SOLUTION FOR INJECTION 20 MG/ML …

Prednisone

A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver. Prednisone was granted FDA approval on 21 February 1955.
Approved
Vet approved
Matched Description: … [A187463] It is biologically inert and converted to [prednisolone] in the liver. …
Matched Categories: … Alimentary Tract and Metabolism ... Prednisolone and Prodrugs ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … PredniSONE Tablets, USP, 20 mg …

Larotrectinib

Larotrectinib is an orally administered inhibitor of tropomyosin receptor kinase (Trk), a receptor tyrosine kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays an important role in tumor cell growth and survival. Upon administration, larotrectinib binds to Trk, thereby preventing neurotrophin-Trk interaction and...
Approved
Investigational
Matched Description: … Trk activation, which results in both the induction of cellular apoptosis and the inhibition of cell ... kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays an important ... role in tumor cell growth and survival. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … VITRAKVI 20 MG/ML ORAL ÇÖZELTİ, 2x50 ML …

Cisatracurium

Cisatracurium is a non-depolarising neuromuscular blocking agent of the benzylisoquinolinium class, available in its salt form, cisatracurium besylate.[A243416,A253592] Cisatracurium has an intermediate duration of action and is one of the most commonly used neuromuscular blocking agents in intensive care.[A253592,A253597]. Cisatracurium acts on cholinergic receptors, blocking neuromuscular transmission. This action is...
Approved
Investigational
Matched Description: … Cisatracurium is a non-depolarising neuromuscular blocking agent of the benzylisoquinolinium class, available ... [A243416,A253592] Cisatracurium has an intermediate duration of action and is one of the most commonly ... [A243416,A253592] Cisatracurium is an R-cis-R-cis isomer of [atracurium] and has approximately 3 times …
Matched Products: … NİMBEX 20 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADET …

Baloxavir marboxil

Baloxavir marboxil is an antiviral drug used to treat influenza. More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza virus proliferation.[A39895, A251755] It is a prodrug of baloxavir with an improved absorption profile than its active metabolite due to the addition of a phenolic hydroxyl...
Approved
Investigational
Matched Description: … active metabolite due to the addition of a phenolic hydroxyl group to its structure. ... [A39895, A251755] It is a prodrug of [baloxavir] [L42855] with an improved absorption profile than its …
Matched Categories: … Baloxavir and prodrugs …
Matched Products: … XOFLUZA 20 MG FİLM KAPLI TABLET, 2 ADET ... XOFLUZA 20 MG FİLM KAPLI TABLET, 4 ADET …

Vinorelbine

Vinorelbine is an anti-mitotic chemotherapy drug that is used in the treatment of several types of malignancies, including breast cancer and non-small cell lung cancer (NSCLC) . It was initially approved in the USA in 1990's for the treatment of NSCLC . It is a third-generation vinca alkaloid. The introduction...
Approved
Investigational
Matched Description: … , including breast cancer and non-small cell lung cancer (NSCLC) [L1998]. ... Vinorelbine is an anti-mitotic chemotherapy drug that is used in the treatment of several types of malignancies ... genetics on the clearance of this drug [L2002]. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … NAVELBINE 20 MG ... NAVELBINE® 20 MG ... Navelbine 20 mg - Kapseln …

Misoprostol

Misoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages, prevent post partum hemorrhage, and also for first trimester abortions.[L7616,L7619,A181589,A181583,A181697] The stimulation of prostaglandin receptors in the stomach reduces gastric acid secretion, while stimulating these receptors in the uterus and cervix can increase the...
Approved
Matched Description: … strength and frequency of contractions and decrease cervical tone. ... Misoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages ... [L7616,L7619,A181589,A181583,A181697] The stimulation of prostaglandin receptors in the stomach reduces …
Matched Mixtures name: … ARTHROTEC 75 MG TABLET, 20 ADET ... DIFEMIS 50 MG/0.2 MG TABLET, 20 ADET ... DIFEMIS 75 MG/0.2 MG TABLET, 20 ADET …
Matched Categories: … Antiinflammatory and Antirheumatic Products, Non-Steroids ... naproxen and misoprostol ... Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Antiinflammatory and Antirheumatic Products …
Matched Products: … CYTOTEC 200 MCG TABLET, 28 ADET …

Nomifensine

Nomifensine, formerly marketed as Merital capsules, was associated with an increased incidence of hemolytic anemia. The approved application holder removed Merital capsules from the market on January 23, 1986. FDA published a notice of its determination that Merital capsules were removed from the market for safety reasons (see the Federal...
Approved
Withdrawn
Matched Description: … Approval of the NDA for Merital capsules was withdrawn on March 20, 1992 (see the Federal Register of ... Also withdrawn from the Canadian and UK markets. ... March 20, 1992 (57 FR 9729)). …

Articaine

Articaine is a dental local anesthetic. Articaine is widely used around the world and is the most popular local anesthetic in many European countries.
Approved
Matched Description: … Articaine is widely used around the world and is the most popular local anesthetic in many European countries …
Matched Mixtures name: … FULLCAIN AMPUL , 20 AMPUL ... FULLCAIN FORT AMPUL , 20 AMPUL ... ULTRACAIN DS 40 MG/Ml+6 MCG/ML ENJEKSİYONLUK ÇÖZELTİ, 20 AMPUL …

Omaveloxolone

Omaveloxolone (RTA-408) is a semisynthetic oleanane triterpenoid with antioxidant and anti-inflammatory properties.[A257534,A257539] Omaveloxolone acts as an activator of nuclear factor (erythroid-derived 2)-like 2 (Nrf2), a transcription factor that mitigates oxidative stress. In patients with Friedreich's ataxia, a genetic disease involving mitochondrial dysfunction, the Nrf2 pathway is impaired, and Nrf2 activity...
Approved
Investigational
Matched Synonyms: … Propanamide, N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoro- …
Matched Description: … in adults and adolescents aged 16 years and older. ... group of patients. ... and oxidative stress has also been evaluated. …

Zinc gluconate

Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA . It is available as a trace mineral supplement and over the counter as a lozenge form for...
Approved
Vet approved
Matched Description: … of common colds and with decreased symptom severity. ... salts (oral rehydration solution), may reduce both the duration and severity of diarrheal episodes for ... It is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration …
Matched Mixtures name: … One A Day With Non-medicinal Echinacea ... Multivitamin and Mineral ... Zinc and Algin Tab Nu Life …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Alimentary Tract and Metabolism …

Drospirenone

Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with Ethinyl estradiol. Most recently, it was approved by both Health Canada and the FDA in combination with Estetrol as an oral contraceptive therapy.[L33199,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to...
Approved
Matched Description: … such as drospirenone exists but remains lower than the risk of this condition during pregnancy and during ... Some studies have demonstrated a significantly increased risk and some demonstrating no risk of thromboembolic ... the postpartum period, and this should be considered when assessing potential risks of hormonal contraceptive …
Matched Mixtures name: … Drospirenone and Ethinyl Estradiol Tablets 28 ... Drospirenone and Ethinyl Estradiol Tablets USP 28 ... DROSPERA® 20 …
Matched Categories: … Sex Hormones and Modulators of the Genital System ... drospirenone and estetrol ... drospirenone and estrogen ... drospirenone and ethinylestradiol ... Genito Urinary System and Sex Hormones …
Matched Products: … ZLYNDA 4 MG FİLM KAPLI TABLET, 28 ADET …

Sotrovimab

Sotrovimab (VIR-7831), also known as GSK4182136, is a monoclonal antibody that can neutralize the SARS-CoV-2 virus. Sotrovimab was initially been granted emergency use authorization (EUA) to treat mild-to-moderate COVID-19 on May 26, 2021, based on interim results from a clinical trial, where sotrovimab was found to reduce the risk of...
Approved
Investigational
Matched Description: … 2021, based on interim results from a clinical trial, where sotrovimab was found to reduce the risk of …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …

Sertindole

Sertindole, a neuroleptic, is one of the newer antipsychotic medications available. Serdolect is developed by the Danish pharmaceutical company H. Lundbeck. It is a phenylindole derivative used in the treatment of schizophrenia. It was first marketed in 1996 in several European countries before being withdrawn two years later because of...
Approved
Investigational
Withdrawn
Matched Description: … It has once again been approved and should soon be available on the French and Australian market. ... It is a phenylindole derivative used in the treatment of schizophrenia. ... Sertindole, a neuroleptic, is one of the newer antipsychotic medications available. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … SERDOLECT 20 MG FILM KAPLI TABLET, 28 ADET ... Serdolect 20 mg - Filmtabletten ... SERDOLECT 12 MG FILM KAPLI TABLET, 28 ADET …

Erenumab

Erenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to bind and antagonize the calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines. Aimovig, as released and marketed by Novartis and Amgen, is in fact a novel therapeutic approach as the first and only...
Approved
Investigational
Matched Description: … It is composed of 2 heavy chains, each containing 456 amino acids, and 2 light chains of the lambda subclass ... Aimovig, as released and marketed by Novartis and Amgen, is in fact a novel therapeutic approach as the ... , each containing 216 amino acids, with an approximate molecular weight of 150 kDa [FDA Label]. …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Thallous chloride Tl-201

Approved

Propofol

Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness,...
Approved
Investigational
Vet approved
Matched Description: … status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries ... Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia ... using a combination of medications. …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … CRIXOFOL 10MG/1MLAMPOLLA POR 20 ML ... RAPIFOL INYECCION 20 ML (PROPOFOL 10 MG/ML) ... PROPOFOL % 1 FRESENIUS 10 GR 20 ML AMPUL, 5 ADET …

Clavulanic acid

Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with Amoxicillin or Ticarcillin to fight antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of susceptible bacterial infections. Clavulanic acid is derived from the organism Streptomyces clavuligerus. When it is combined with amoxicillin, clavulanic acid is...
Approved
Vet approved
Matched Description: … antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of …
Matched Mixtures name: … KLAVUNAT BID 200/28 MG 70 ML ORAL SUSPANSIYON ... KLAVUNAT BID 200/28 MG 100 ML ORAL SUSPANSIYON ... CROXILEX-BID 200/28 ORAL SUSPANSIYON ICIN KURU TOZ, 70 ML …

Gadobenic acid

Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based contrast agent (GBCA) used primarily for MR imaging of the liver. It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and R2 relaxivity....
Approved
Investigational
Matched Description: … gadobenate dimeglumine, is a linear MRI gadolinium-based contrast agent (GBCA) used primarily for MR imaging of ... [A263166] As gadobenate dimeglumine is specifically taken up by hepatocytes and excreted through the ... other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and …
Matched Salts cas: … 127000-20-8 …
Matched Categories: … Diagnostic Uses of Chemicals …
Matched Products: … MULTIHANCE INJECTION 20 ML ... MULTIHANCE TEK DOZLUK IV ENJEKSIYONLUK COZELTI ICEREN FLAKON, 20 ML …

Tetryzoline

Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral alpha (α)-adrenergic properties. Available since the 1950s, tetryzoline is a selective α1-receptor agonist that is used as an ocular and nasal decongestant. Tetryzoline is found in a wide array of over-the-counter eye drops, including the most...
Approved
Matched Description: … Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral ... [A7045, A231769] It has also been misused for non-therapeutic purposes as a causative drug for several ... cases of drug-facilitated sexual assault. …
Matched Mixtures name: … Up and Up Ultra Itchy Relief ... Redness reliever and Lubricant ... Seasonal itchy and Red eye relief …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Foster and Thrive Original Formula Eye Drops ... Walgreens Eye Drops Original 15mL and twin pack …

Nutmeg

Nutmeg allergenic extract is used in allergenic testing.
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome ... Non-Standardized Food Allergenic Extract ... Non-Standardized Plant Allergenic Extract …
Displaying drugs 176 - 200 of 14844 in total