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Displaying drugs 176 - 200 of 9012 in total

Oxycodone

Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone...
Approved
Illicit
Investigational
Matched Iupac: … (1S,5R,13R,17S)-17-hydroxy-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18 …
Matched Mixtures name: … OXYCODON COMP 1A 10/5MG ... OXYCODON COMP 1A 10/5MG ... OXYCODON COMP 1A 10/5MG …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … Supeudol 10 ... OxyNorm 10 mg Kapseln ... OXIDONA® 10 MG …

Chloroquine

Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. Chloroquine and its derivative hydroxychloroquine have since been repurposed for the treatment of a...
Approved
Investigational
Vet approved
Matched Description: … [A191655] It was the drug of choice to treat malaria until the development of newer antimalarials such ... Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria ... a number of other conditions including HIV, systemic lupus erythematosus, and rheumatoid arthritis. …
Matched Products: … KUTLU 250 MG FİLM KAPLI TABLET, 10 ADET ... OROQUİNE 250 MG/5 ML IV İNFÜZYONLUK ÇÖZELTİ , 10 ADET …

Levocabastine

Levocabastine is a selective second-generation H1-receptor antagonist used for allergic conjunctivitis. Levocabastine was discovered at Janssen Pharmaceutica in 1979.
Approved
Investigational

Acetohydroxamic acid

Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly. It is used, in addition to antibiotics...
Approved
Matched Description: … In the urine, it acts as an antagonist of the bacterial enzyme urease. …
Matched Products: … CIPROFLOXACINO 100 MG/10 ML INYECTABLE ... CIPROFLOXACINO 100 MG / 10 ML INYECTABLE ... CIPROFLOXACINO100 MG /10 ML SOLUCIONINYECTABLE …

Human immunoglobulin G

Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ion exchange chromatography. IVIg contains the same distribution of IgG antibody subclasses as is found in the general human population....
Approved
Investigational
Matched Description: … Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human ... IVIg is used in the treatment of immunodeficiencies, as well as autoimmune and inflammatory disorders ... IVIg contains the same distribution of IgG antibody subclasses as is found in the general human population …
Matched Products: … OCTAGAM 10% ... FLEBOGAMMA 10% DIF SOLUCION PARA PERFUSION 10 G/100ML ... Flebogamma 10% …

Methimazole

Methimazole is a thionamide antithyroid agent that inhibits the synthesis of thyroid hormones.[A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949 and is now commonly used in the management of hyperthyroidism, particularly in those for whom more aggressive options such as surgery or radioactive iodine therapy are inappropriate.[L8336,L8339]...
Approved
Matched Description: … [L8336,L8339] On a weight basis, methimazole is 10 times more potent than the other major antithyroid ... Methimazole is a thionamide antithyroid agent that inhibits the synthesis of thyroid hormones. ... first introduced as an antithyroid agent in 1949[A184502] and is now commonly used in the management of …
Matched Products: … VELTHROM 10 ... THYROZOL 10 ... THYROZOL TABLET 10 mg …

Alfuzosin

Benign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads to lower urinary tract symptoms in men, such as urgency, frequency and changes to urine flow. The prevalence of BPH is as high as 50%-60% for males in their 60's, and this prevalence increases...
Approved
Investigational
Matched Description: … 80%-90% of those over 70. ... Benign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads ... The prevalence of BPH is as high as 50%-60% for males in their 60's, and this prevalence increases to …
Matched Products: … XATRAL XL 10 MG ... ALFUTOR ER TABLETS 10 MG ... XATRAL XL TABLET 10 mg …

Perflutren

Perflutren, a diagnostic drug that is intended to be used for contrast enhancement during the indicated echocardiographic procedures, is comprised of lipid-coated microspheres filled with octafluoropropane(OFP) gas. When exposed to ultrasound waves, the microspheres resonate and "echo" strong signals back to the ultrasound machine. The difference in density between the...
Approved
Matched Description: … During echocardiography, activated Perflutren enhances images of the inner edges or borders of the heart ... to be used for contrast enhancement during the indicated echocardiographic procedures, is comprised of ... difference in density between the gas-filled bubbles and the blood around them creates an increased level of …
Matched Categories: … Diagnostic Uses of Chemicals …

Cefditoren

Cefditoren is an oral third-generation cephalosporin. It is commonly marketed under the trade name Spectracef by Cornerstone BioPharma.
Approved
Investigational
Matched Products: … CEFITEN 30 MG SASE, 21 ADET ... CEFITEN 50 MG SASE, 21 ADET ... MEIACT MS FINE GRANULES 10% …

Meticillin

One of the penicillins which is resistant to penicillinase but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection.
Approved
Investigational
Matched Description: … One of the penicillins which is resistant to penicillinase but susceptible to a penicillin-binding protein …
Matched Categories: … combinations of penicillins …

Sarecycline

Sarecycline is a semi-synthetic derivative of tetracycline that was initially discovered by Paratek Pharmaceuticals from Boston, MA but then licensed to Warner Chilcott of Rockaway, NJ in July of 2007 . After completing various phase-II and phase-III trials demonstrating its effectiveness in treating moderate to severe facial acne vulgaris [A39993,...
Approved
Investigational
Matched Description: … from Boston, MA but then licensed to Warner Chilcott of Rockaway, NJ in July of 2007 [A40005]. ... inflammatory lesions of non-nodular moderate to severe acne vulgaris in patients nine years of age and ... of young adults aged 12 to 25 years globally - with the possibility of permanent physical and mental …
Matched Categories: … combinations of tetracyclines …

Temocillin

Temocillin has been investigated in Infection, Liver Dysfunction, and Urinary Tract Infection.
Approved
Investigational
Matched Categories: … combinations of penicillins …

Phthalylsulfathiazole

Phthalylsulfathiazole is a broad spectrum antibiotic which is part of the drug class, sulfonamides. It was used as an antibiotic for bowel surgery, and for infections of the colon .
Approved
Matched Description: … It was used as an antibiotic for bowel surgery, and for infections of the colon [A175006]. ... Phthalylsulfathiazole is a broad spectrum antibiotic which is part of the drug class, sulfonamides. …
Matched Categories: … combinations of sulfonamides …

Gallium Ga-68 gozetotide

Gallium (Ga) 68 prostate-specific membrane antigen (PSMA)-11, or Ga-68 gozetotide, is a radiopharmaceutical agent used to identify and assess prostate-specific membrane antigen (PSMA)-positive lesions in adult men with prostate cancer during positron emission tomography (PET). Prostate cancer is one of the most commonly diagnosed cancers among men in Western countries...
Approved
Matched Description: … [L43542] In December of the same year, the drug was fully authorized by the EMA. ... [L26981] Prostate cancer is one of the most commonly diagnosed cancers among men in Western countries ... Human Use (CHMP) recommended Ga-68 gozetotide be granted marketing authorization for the diagnosis of …
Matched Categories: … Diagnostic Uses of Chemicals …

Methadone

Methadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist. As a full MOR agonist, methadone mimics the natural effects of the body's opioids, endorphins, and enkephalins through the release of neurotransmitters involved in pain transmission. It also has a...
Approved
Matched Description: … , and a long duration of action. ... Provision of OAT is often combined with education about harm reduction including use of clean needles ... The intention of substitution of illicit opioids with the long-acting opioids used in OAT is to prevent …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … Methasan 10 mg-Tabletten ... METHADOSE® 10 MG TABLETAS ... ABL METAPAD COMPRIMIDOS 10 MG …

Acetylcysteine

Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.
Approved
Investigational
Matched Description: … Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of ... [L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications …
Matched Mixtures name: … Medi-10 ... AMINOVEN INFANT 10% ... AMINOPLASMAL-10% E INFUSION …
Matched Products: … ACT 300MG/3ML (%10) ENJEKSİYONLUK ÇÖZELTİ, 10 ADET ... FLUIMUCIL® 10 % ... XPECTO 300 MG SAŞE, 10 ADET …

Protriptyline

Protriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, protriptyline does not affect mood or arousal, but may cause sedation. In depressed individuals, protriptyline exerts a positive...
Approved
Matched Description: … Protriptyline may be used for the treatment of depression. ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... See toxicity section below for a complete listing of side effects. …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Latanoprost

Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular pressure (IOP). It was initially approved by the FDA in 1998. Latanoprost is the first topical prostaglandin F2 alpha analog used for glaucoma treatment. It has been found to be well-tolerated and its use...
Approved
Investigational
Matched Description: … Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular …

Enalaprilat

Enalaprilat is the active metabolite of the orally available pro-drug, enalapril. Used in the treatment of hypertension, enalapril is an ACE inhibitor that prevents Angiotensin Converting Enzyme (ACE) from transforming angiotensin I into angiotensin II. As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule of...
Approved
Matched Description: … Enalaprilat is the active metabolite of the orally available pro-drug, [enalapril]. ... Used in the treatment of hypertension, enalapril is an ACE inhibitor that prevents Angiotensin Converting ... the kidney, down-regulation of this protein results in reduced blood pressure and blood fluid volume …

Avelumab

Avelumab is a human IgG1 lambda monoclonal antibody that binds programmed cell death ligand-1 (PD-L1) to block its interaction with its receptors found on T cells and antigen-presenting cells. Avelumab was first approved by the FDA on March 23, 2017. On September 18 and December 18 of the same year,...
Approved
Investigational
Matched Description: … It is used in the treatment of Merkel cell carcinoma, metastatic urothelial carcinoma, or renal cell ... [A261496] On September 18 and December 18 of the same year, it was also granted approval by EMA [L48126 …
Matched Products: … BAVENCIO 200 MG/10 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 FLAKON …

Tenoxicam

Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.
Approved
Matched Products: … TILCOTIL 20 MG 10 SUPP ... TENOKTIL 20 MG KAPSÜL, 10 ADET ... ARTOXAN 20 MG FILM TABLET ,10 ADET …

Potassium bicarbonate

Potassium bicarbonate is a white, crystalline, slightly alkaline and salty substance. It is produced by the passage of carbon dioxide through an aqueous potassium carbonate solution. It is used in medicine as an antacid. It is registered in the FDA under the section of suitable, safe and effective ingredients for...
Approved
Matched Description: … It is produced by the passage of carbon dioxide through an aqueous potassium carbonate solution. ... [T141] It is registered in the FDA under the section of suitable, safe and effective ingredients for …
Matched Mixtures name: … GALVİKS ADVANCE 1000 MG+200 MG/10 ML ORAL SÜSPANSİYON, 200 ML …
Matched Products: … Effer-K 10 mEq Unflavored ... Effer-K 10 mEq Cherry Vanilla …

Nebivolol

Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than atenolol, propranolol, or pindolol. Nebivolol and other beta...
Approved
Investigational
Matched Description: … Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other …
Matched Mixtures name: … AMLONEB 10 MG/10 MG TABLET, 30 ADET ... AMLONEB 10 MG/10 MG TABLET, 90 ADET ... AMLONEB 10 MG/5 MG TABLET, 30 ADET …
Matched Products: … VASCURA 10 MG TABLET, 28 ADET ... VASOXEN 10 MG TABLET, 84 TABLET ... NEXIVOL 10 MG TABLET, 28 ADET …

Trolamine salicylate

Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid. It is a topical analgesic used for temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and bruises. Unlike other topical analgesics, trolamine...
Approved
Matched Description: … Triethanolamine neutralizes the acidity of the salicylic acid. ... As with other salicylates, trolamine salicylate is an inhibitor of cyclo-oxygenase (COX) enzymes with ... It is a topical analgesic used for temporary relief of minor pain associated with arthritis, simple backache …
Matched Products: … Aspercreme 10% ... Aspercreme Creme Rub 10% ... Myoflex Regular Cream 10% …

Fondaparinux

Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule. It is structurally similar to polymeric glycosaminoglycan heparin and heparan sulfate (HS) when they are cleaved into monomeric units. The monomeric sequence in heparin and HS...
Approved
Investigational
Matched Description: … a O-methyl group at the reducing end of the molecule. ... ); and in the management of ST segment elevation myocardial infarction (STEMI). ... Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and …
Matched Products: … ARIXTRA 10 MG/0.8 ML S.C. ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR SIRINGA, 10 ADET ... COZELTI ICEREN KULLANIMA HAZIR SIRINGA, 10 ADET ... ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR SIRINGA, 10 ADET …
Displaying drugs 176 - 200 of 9012 in total