Displaying drugs 176 - 200 of 641 in total
Desogestrel
Desogestrel, a prodrug, is a third generation progestogen and hence, a member of the gonane family which was largely used in Europe before being approved in the US and Canada. It was firstly generated from a study that showed that 11-beta and 11-alkylidene substituent in nortestosterone can enhance the biological...
Approved
Matched Synonyms: … 13-Ethyl-11-methylene-18,19-dinor-17α-pregn-4-en-20-yn-17-ol …
Matched Mixtures name: … Desofemine 20 Mikrogramm/150 Mikrogramm Filmtabletten ... Desogestrel/Ethinylestradiol Effik 150 Mikrogramm/20 Mikrogramm Tabletten …
Matched Mixtures name: … Desofemine 20 Mikrogramm/150 Mikrogramm Filmtabletten ... Desogestrel/Ethinylestradiol Effik 150 Mikrogramm/20 Mikrogramm Tabletten …
Naloxegol
Naloxegol, for "PEGylated naloxol" is a peripherally-selective opioid antagonist developed by AstraZeneca. It was approved by the FDA in September 2014 and is indicated for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non‑cancer pain. The advantage of naloxegol over the opioid antagonist naloxone is that its...
Approved
Matched Synonyms: … (5α,6α)-17-Allyl-6-[(20-hydroxy-3,6,9,12,15,18-hexaoxaicos-1-yl)oxy]-4,5-epoxymorphinan-3,14-diol …
Ciprocinonide
Approved
Investigational
Procinonide
Approved
Investigational
Tibolone
Tibolone is a synthetic steroid hormone drug, which is mainly non-selective in its binding profile, acting as an agonist primarily at estrogen receptors (ER), with a preference for ER alpha .
Tibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses estrogenic, androgenic...
Approved
Investigational
Matched Synonyms: … 17-hydroxy-7alpha-methyl-19-nor-17alpha-pregn-5(10)-en-20-yn-3-one …
Ozanimod
Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. It was developed by Celgene (now acquired by Bristol-Myers Squibb) and was approved by the FDA on March 26, 2020.[L12573,L12582] The US approval was followed by the approval in Canada...
Approved
Investigational
Matched Description: … [L12573,L12582] The US approval was followed by the approval in Canada on October 2, 2020. ... by Celgene (now acquired by Bristol-Myers Squibb) [L11025] and was approved by the FDA on March 26, 2020 …
Temoporfin
Temoporfin is a photosensitizing agent used in the treatment of squamous cell carcinoma of the head and neck [FDA Label]. It was first authorized for market by the European Medicines Agency in October 2001. It is currently available under the brand name Foscan.
Approved
Investigational
Influenza B virus B/Massachusetts/2/2012 BX-51B hemagglutinin antigen (propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Influenza A virus A/Uruguay/716/2007(H3N2) live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Methylprednisolone
Methylprednisolone is a prednisolone derivative glucocorticoid with higher potency than prednisone. It was first described in the literature in the late 1950s.[A188811,A188814]
Methylprednisolone was granted FDA approval on 24 October 1957. In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with...
Approved
Vet approved
Matched Products: … PREDNOL 4 MG TABLET, 20 ADET ... PREDNOL 16 MG TABLET, 20 ADET ... METI-KORT 4 MG TABLET, 20 ADET …
Belantamab mafodotin
Belantamab mafodotin, or GSK2857916, is an afucosylated monoclonal antibody that targets B cell maturation antigen conjugated to the microtubule disrupter monomethyl auristatin-F (MMAF). Belantamab mafodotin was granted FDA accelerated approval on 5 August 2020 for the treatment of multiple myeloma; however, its manufacturer began the process for withdrawal of the...
Approved
Matched Description: … [A216756]
Belantamab mafodotin was granted FDA accelerated approval on 5 August 2020 for the treatment …
Lactic acid
A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste. It is produced by fermentation of a sugar source, such as...
Approved
Vet approved
Matched Description: … active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020 …
Dulaglutide
Dulaglutide, marketed by Eli Lilly as Trulicity, is a once-weekly subcutaneous glucagon-like peptide-1 (GLP-1) receptor agonist designed using recombinant DNA technology; it has been approved as an adjunct therapy to diet and exercise in the management of 2 diabetes (T2DM). Dulaglutide was initially approved by the FDA in 2014, and...
Approved
Investigational
Matched Description: … [A236070] Dulaglutide was initially approved by the FDA in 2014, and in February 2020 was approved for …
Regdanvimab
Regdanvimab (CT-P59) is a recombinant human IgG1 monoclonal antibody directed at the receptor binding domain (RBD) of the SARS-CoV-2 spike protein. It blocks the interaction between viral spike proteins and angiotensin-converting enzyme 2 (ACE2) that allows for viral entry into the cell, thereby inhibiting the virus' ability to replicate. Trials...
Approved
Investigational
Matched Description: … investigating the use of regdanvimab as a therapeutic candidate for the treatment of COVID-19 began in mid-2020 …
Dydrogesterone
A synthetic progestational hormone with no androgenic or estrogenic properties. Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit ovulation.
Approved
Investigational
Withdrawn
Matched Products: … DUPHASTON 10 MG FİLM KAPLI TABLET, 20 ADET …
Dexamethasone
Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions. Developed in 1957, it is structurally similar to other corticosteroids like hydrocortisone and prednisolone. Dexamethasone was granted FDA approval on 30 October 1958....
Approved
Investigational
Vet approved
Matched Description: … L10695] In a press release for the Randomized Evaluation of COVID-19 Therapy (RECOVERY) trial on 16 June 2020 …
Matched Mixtures name: … NETILDEX GOZ DAMLASI %0,1 DEKSAMETAZON + %0,3 NETILMISIN 0,3 ML × 20 ADET …
Matched Products: … DEKORT 4 MG TABLET, 20 ADET ... DEKORT 8 MG TABLET, 20 ADET ... KORDEXA 4 MG TABLET, 20 ADET …
Matched Mixtures name: … NETILDEX GOZ DAMLASI %0,1 DEKSAMETAZON + %0,3 NETILMISIN 0,3 ML × 20 ADET …
Matched Products: … DEKORT 4 MG TABLET, 20 ADET ... DEKORT 8 MG TABLET, 20 ADET ... KORDEXA 4 MG TABLET, 20 ADET …
Flumethasone
Flumethasone is a moderately potent difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties. As it is a privalate salt, its anti-inflammatory action is concentrated at the site of application. This local effect on diseased areas results in a prompt decrease in inflammation, exudation and itching.
Approved
Vet approved
Ouabain
A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like digitalis. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-exchanging ATPase.
Approved
Matched Synonyms: … 3-(α-L-rhamnopyranosyloxy)-1β,5β,11α,14,19-pentahydroxy-5β-card-20(22)-enolide …
Clobetasol propionate
Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors. It has demonstrated superior activity compared to fluocinonide and was first described in the literature in 1974. Clobetasol Propionate was granted FDA approval on 27 December 1985.
Approved
Vibegron
Vibegron is a potent, selective beta-3 adrenergic receptor (β3) agonist that relaxes the detrusor smooth muscle of the bladder, thereby increasing bladder capacity. Vibegron was first approved in Japan in September 2018 for the treatment of overactive bladder, a condition associated with distressing symptoms of urge urinary incontinence, urgency, and...
Approved
Investigational
Matched Description: … On December 23, 2020, vibegron was approved for the same indication in adults. …
Cabazitaxel
Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and induces tumour cell death. Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to...
Approved
Matched Synonyms: … .,20-EPOXYTAX-11-ENE-2.ALPHA.,4,13.ALPHA. …
Matched Products: … Cabazitaxel G.L. 20 mg/ml-Konzentrat zur Herstellung einer Infusionslösung ... Cabazitaxel STADA 20 mg/ml Konzentrat zur Herstellung einer Infusionslösung ... Cabazitaxel Viatris 20 mg/ml Konzentrat zur Herstellung einer Infusionslösung …
Matched Products: … Cabazitaxel G.L. 20 mg/ml-Konzentrat zur Herstellung einer Infusionslösung ... Cabazitaxel STADA 20 mg/ml Konzentrat zur Herstellung einer Infusionslösung ... Cabazitaxel Viatris 20 mg/ml Konzentrat zur Herstellung einer Infusionslösung …
Deslanoside
Deacetyllanatoside C. A cardiotonic glycoside from the leaves of Digitalis lanata.
Approved
Matched Synonyms: … 2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl]oxy}-12,14-dihydroxycard-20 ... dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-3β,5β,12β-card-20 …
Hydroxychloroquine
Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. Hydroxychloroquine is an aminoquinoline like chloroquine. It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and systemic lupus erythematosus. Hydroxychloroquine is also used for the prophylaxis of malaria in...
Approved
Matched Description: … authorization for hydroxychloroquine and [chloroquine] in the treatment of COVID-19 was revoked on 15 June 2020 …
Mannitol
Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including the brain and cerebrospinal fluid, into interstitial fluid and plasma. As a...
Approved
Investigational
Matched Description: … On October 30, 2020, mannitol was approved by the FDA as add-on maintenance therapy for the control of …
Matched Mixtures name: … OSMOFUNDIN INJECTION 20% …
Matched Products: … OSMOROL 20 ... BRAUN OSMOFUNDIN 20% ... Osmitrol Injection 20% …
Matched Mixtures name: … OSMOFUNDIN INJECTION 20% …
Matched Products: … OSMOROL 20 ... BRAUN OSMOFUNDIN 20% ... Osmitrol Injection 20% …
Lorcaserin
Lorcaserin (previously APD-356), a highly selective 5HT2C receptor agonist, is used for the treatment of obesity. It has been shown to reduce body weight and food intake in animal models of obesity, and it is thought that targeting the 5HT2C receptor may alter body weight by regulating satiety. Lorcaserin is...
Approved
Withdrawn
Matched Description: … hydrochloride tablets, 10 mg) and Belviq XR (lorcaserin hydrochloride extended-release tablets, 20 mg ... In February 2020, the FDA issued a Drug Safety Communication requesting the manufacturer of Belviq (lorcaserin …
Displaying drugs 176 - 200 of 641 in total