Displaying drugs 1976 - 2000 of 9325 in total
Zucapsaicin
Zucapsaicin, the cis-isomer of capsaicin, is a topical analgesic used to treat osteoarthritis of the knee and other neuropathic pain. It is a modulator of transient receptor potential cation channel subfamily V member 1 (TRPV-1), also known as the vanilloid or capsaicin receptor 1, that reduces pain and improves articular...
Approved
Investigational
Matched Iupac: … (6Z)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide …
Matched Description: … It is a modulator of transient receptor potential cation channel subfamily V member 1 (TRPV-1), also ... known as the vanilloid or capsaicin receptor 1, that reduces pain and improves articular functions. …
Matched Description: … It is a modulator of transient receptor potential cation channel subfamily V member 1 (TRPV-1), also ... known as the vanilloid or capsaicin receptor 1, that reduces pain and improves articular functions. …
Influenza A virus A/Michigan/45/2015 (H1N1) recombinant hemagglutinin antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Baclofen
Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Salts cas: … 28311-31-1 …
Matched Products: … Baclofen Sintetica 2 mg/ml Intrathekal Infusionslösung ... BACLOFEN ® 0.05 MG/ 1 ML ... Lioresal intrathekal 0,05 mg/1 ml - Ampullen …
Matched Products: … Baclofen Sintetica 2 mg/ml Intrathekal Infusionslösung ... BACLOFEN ® 0.05 MG/ 1 ML ... Lioresal intrathekal 0,05 mg/1 ml - Ampullen …
Risankizumab
Risankizumab is a fully humanized IgG1 monoclonal antibody (mAb) directed against interleukin 23 (IL-23). It gained its first global approval in Japan in March 2019, followed by approval in Canada, the US, and Europe in April 2019. Risankizumab is used to treat plaque psoriasis, psoriatic arthritis, and Crohn's disease.[L39885,L44191,L44231] Risankizumab...
Approved
Investigational
Matched Products: … Skyrizi 150 mg/ml Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem, 1 ADET ... SKYRİZİ 150 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …
Amylocaine
Despite the introduction of using cocaine injections for regional anesthesia in 1884, non-addictive substitutes were sought after immediately . Finally, in 1903 the world's first synthetic and non-addictive local anesthetic, amylocaine, was synthesized and patented under the name Forneaucaine by Ernest Fourneau at the Pasteur Institute . Elsewhere in English...
Approved
Withdrawn
Matched Synonyms: … 1-(Dimethylamino)-2-methyl-2-butanol benzoate …
Matched Iupac: … 1-(dimethylamino)-2-methylbutan-2-yl benzoate …
Matched Salts cas: … 532-59-2 …
Matched Iupac: … 1-(dimethylamino)-2-methylbutan-2-yl benzoate …
Matched Salts cas: … 532-59-2 …
Dipivefrin
Dipivefrin is a prodrug of adrenaline, which is used to treat glaucoma. It is available as ophthalmic solution (eye drops).
Approved
Matched Synonyms: … 1-(3',4'-dipivaloyloxyphenyl)-2-methylamino-1-ethanol ... (±)-4-[1-hydroxy-2-(methylamino)ethyl]-o-phenylene divavalate ... 4-[1-hydroxy-2-(methylamino)ethyl]-o-phenylene divavalate …
Matched Iupac: … 2-[(2,2-dimethylpropanoyl)oxy]-5-[1-hydroxy-2-(methylamino)ethyl]phenyl 2,2-dimethylpropanoate …
Matched Salts cas: … 64019-93-8 …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists ... Adrenergic beta-1 Receptor Agonists ... Adrenergic beta-2 Receptor Agonists …
Matched Iupac: … 2-[(2,2-dimethylpropanoyl)oxy]-5-[1-hydroxy-2-(methylamino)ethyl]phenyl 2,2-dimethylpropanoate …
Matched Salts cas: … 64019-93-8 …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists ... Adrenergic beta-1 Receptor Agonists ... Adrenergic beta-2 Receptor Agonists …
Tafasitamab
Tafasitamab is a humanized, CD19-directed cytolytic monoclonal antibody intended for the treatment of B-cell malignancies. It is produced using recombinant DNA technology in Chinese hamster ovary cells, and contains an IgG1/2 hybrid Fc-domain which has been modified with 2 amino acid substitutions to enhance its cytotoxicity relative to non-engineered anti-CD19...
Approved
Investigational
Matched Description: … It is produced using recombinant DNA technology in Chinese hamster ovary cells, and contains an IgG1/2 ... hybrid Fc-domain which has been modified with 2 amino acid substitutions to enhance its cytotoxicity …
Metoprolol
Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.[A175159, L5530] The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. To this date,...
Approved
Investigational
Matched Synonyms: … 1-(isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol …
Matched Iupac: … 1-[4-(2-methoxyethyl)phenoxy]-3-[(propan-2-yl)amino]propan-2-ol …
Matched Description: … Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives …
Matched Categories: … Adrenergic beta-1 Receptor Antagonists …
Matched Products: … Betaloc IV Inj 1 mg/ml ... ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL ,1 AMPUL ... MEPOLEX 5 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 1 AMPUL …
Matched Iupac: … 1-[4-(2-methoxyethyl)phenoxy]-3-[(propan-2-yl)amino]propan-2-ol …
Matched Description: … Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives …
Matched Categories: … Adrenergic beta-1 Receptor Antagonists …
Matched Products: … Betaloc IV Inj 1 mg/ml ... ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL ,1 AMPUL ... MEPOLEX 5 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 1 AMPUL …
Atorvastatin
Atorvastatin (Lipitor®), is a lipid-lowering drug included in the statin class of medications. By inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and lipid levels, and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,...
Approved
Matched Iupac: … (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic …
Matched Description: … cardiovascular events (heart attack, stroke, coronary revascularization, and coronary death) for every 1 …
Matched Salts cas: … 134523-03-8 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … cardiovascular events (heart attack, stroke, coronary revascularization, and coronary death) for every 1 …
Matched Salts cas: … 134523-03-8 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Aurothioglucose
Aurothioglucose, also known as gold thioglucose, was formerly used to treat rheumatoid arthritis.
Contemporary research on the effect of gold salts treatment began in 1935, primarily to reduce inflammation and to slow disease progression in patients with rheumatoid arthritis . The use of gold compounds has decreased since the 1980s...
Approved
Withdrawn
Matched Iupac: … {[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanyl}gold …
Carisoprodol
Originally approved by the FDA in 1959 [FDA label], carisoprodol is a centrally acting muscle relaxant used in painful musculoskeletal conditions in conjunction with physical therapy and other medications . This drug is available by itself in an oral tablet or combined with aspirin, or in a fixed-dose combination with...
Approved
Matched Synonyms: … (1-methylethyl)carbamic acid 2-(((aminocarbonyl)oxy)methyl)-2-methylpentyl ester ... (±)-2-methyl-2-propyl-1,3-propanediol carbamate isopropylcarbamate ... 2-methyl-2-propyltrimethylene carbamate isopropylcarbamate …
Matched Iupac: … 2-[(carbamoyloxy)methyl]-2-methylpentyl N-(propan-2-yl)carbamate …
Matched Iupac: … 2-[(carbamoyloxy)methyl]-2-methylpentyl N-(propan-2-yl)carbamate …
Influenza A virus A/Wisconsin/588/2019 (H1N1) recombinant hemagglutinin antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Periciazine
Periciazine is a phenothiazine of the piperidine group. It has been shown to reduce pathologic arousal and affective tension in some psychotic patients, while the symptoms of abnormal mental integration are relatively unaffected. It is a sedative phenothiazine with weak antipsychotic properties. It also has adrenolytic, anticholinergic, metabolic and endocrine...
Approved
Investigational
Matched Synonyms: … 2-Cyano-10-(3-(4-hydroxy-1-piperidyl)propyl)phenothiazine ... Cyano-3 ((hydroxy-4 piperidyl-1)-3 propyl)-10 phenothiazine ... 2-Cyano-10-(3-(4-hydroxypiperidino)propyl)phenothiazine …
Matched Iupac: … 10-[3-(4-hydroxypiperidin-1-yl)propyl]-10H-phenothiazine-2-carbonitrile …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists …
Matched Iupac: … 10-[3-(4-hydroxypiperidin-1-yl)propyl]-10H-phenothiazine-2-carbonitrile …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists …
Vincristine
Vincristine is an antitumor vinca alkaloid isolated from Vinca Rosea. It is marketed under several brand names, many of which have different formulations such as Marqibo (liposomal injection) and Vincasar. Vincristine is indicated for the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. vincristine sulfate...
Approved
Investigational
Matched Iupac: … (methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0^{4,12}.0^{5,10}]nonadeca-4(12),5,7,9-tetraen-13-yl]-8- ... formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13 …
Matched Salts cas: … 2068-78-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … VINARIX 2 MG/2 ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... VINCRISTIN SULFAT HEXAL 2 MG/2 ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... VİNCREST 2 MG/2 ML I.V. ENJEKSİYONLUK ÇÖZELTİ …
Matched Salts cas: … 2068-78-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … VINARIX 2 MG/2 ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... VINCRISTIN SULFAT HEXAL 2 MG/2 ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... VİNCREST 2 MG/2 ML I.V. ENJEKSİYONLUK ÇÖZELTİ …
Levosalbutamol
Levosalbutamol, or levalbuterol, is a short-acting β2 adrenergic receptor agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).
Salbutamol has been marketed as a racemic mixture, although beta2-agonist activity resides almost exclusively in the (R)-enantiomer. The enantioselective disposition of salbutamol and the possibility that (S)-salbutamol has...
Approved
Investigational
Matched Iupac: … 4-[(1R)-2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol …
Matched Salts cas: … 50293-90-8 …
Matched Categories: … Adrenergic beta-2 Receptor Agonists …
Matched Salts cas: … 50293-90-8 …
Matched Categories: … Adrenergic beta-2 Receptor Agonists …
Influenza A virus A/Nebraska/14/2019 (H1N1) antigen (MDCK cell derived, propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Oxiconazole
Oxiconazole is an antifungal agent that is commonly found in topical formulations. It is marketed under the brand names Oxistat and Oxistat, and is used in the treatment of various skin infections such as athlete's foot, jock itch and ringworm.
Approved
Matched Synonyms: … 2',4'-Dichloro-2-imidazol-1-ylacetophenone (Z)-[O-(2,4-dichlorobenzyl)oxime] …
Matched Iupac: … (Z)-[1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethylidene][(2,4-dichlorophenyl)methoxy]amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … OXEZOLE %1 KREM, 20 G ... OCERAL %1 KREM, 10 G ... OXEZOLE %1 KREM, 10 G …
Matched Iupac: … (Z)-[1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethylidene][(2,4-dichlorophenyl)methoxy]amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … OXEZOLE %1 KREM, 20 G ... OCERAL %1 KREM, 10 G ... OXEZOLE %1 KREM, 10 G …
Diethylpropion
A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)
Approved
Illicit
Matched Synonyms: … 1-phenyl-2-diethylamino-1-propanone ... 2-(diethylamino)-1-phenyl-1-propanone ... 2-(diethylamino)propiophenone …
Matched Iupac: … 2-(diethylamino)-1-phenylpropan-1-one …
Matched Iupac: … 2-(diethylamino)-1-phenylpropan-1-one …
Entrectinib
Entrectinib is a tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein kinase ROS1, and anaplastic lymphoma kinase (ALK) inhibitor. It was approved by the FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and NTRK gene fusion positive solid tumors. Entrectinib's...
Approved
Investigational
Matched Synonyms: … N-[5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl]-4-(4-methylpiperazin-1-yl)-2-(oxan-4-ylamino)benzamide …
Matched Iupac: … N-{5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl}-4-(4-methylpiperazin-1-yl)-2-[(oxan-4-yl)amino]benzamide …
Matched Iupac: … N-{5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl}-4-(4-methylpiperazin-1-yl)-2-[(oxan-4-yl)amino]benzamide …
Influenza B virus B/Austria/1359417/2021 BVR-26 hemagglutinin antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Lamotrigine
Lamotrigine is an antiepileptic drug belonging in the phenyltriazine class. It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. Lamotrigine is the first medication since lithium granted Food and Drug Administration (FDA) approval for the maintenance treatment of bipolar type I. It...
Approved
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … LAMICTAL DISPERSIBLE TABLET 2 mg ... Lamictal 2 mg Tabletten (kaubar/suspendierbar) ... LAMICTAL® 2 MG TABLETAS DISPERSABLES …
Matched Products: … LAMICTAL DISPERSIBLE TABLET 2 mg ... Lamictal 2 mg Tabletten (kaubar/suspendierbar) ... LAMICTAL® 2 MG TABLETAS DISPERSABLES …
Ibritumomab tiuxetan
Indium or yttrium conjugated murine IgG1 kappa monoclonal antibody directed against the CD20 antigen, which is found on the surface of normal and malignant B lymphocytes. Ibritumomab is produced in Chinese hamster ovary cells and is composed of two murine gamma 1 heavy chains of 445 amino acids each and...
Approved
Investigational
Matched Description: … Ibritumomab is produced in Chinese hamster ovary cells and is composed of two murine gamma 1 heavy chains …
Pemirolast
Pemirolast potassium is a slightly yellow powder that is soluble in water. It is a mast cell stabilizer that acts as an antiallergic agent. As an ophthalmic aqueous sterile solution, pemirolast is used for the prevention of itching of the eyes caused by allergies such as hay fever, and allergic...
Approved
Investigational
Matched Iupac: … 9-methyl-3-(2H-1,2,3,4-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Brexpiprazole
Brexpiprazole is an atypical antipsychotic and a novel D2 dopamine and serotonin 1A partial agonist called serotonin-dopamine activity modulator (SDAM). It has a high affinity for serotonin, dopamine and alpha (α)-adrenergic receptors. Although it is structurally similar to aripiprazole, brexpiprazole has different binding affinities for dopamine and serotonin receptors. Compared...
Approved
Investigational
Matched Iupac: … 7-{4-[4-(1-benzothiophen-4-yl)piperazin-1-yl]butoxy}-1,2-dihydroquinolin-2-one …
Matched Salts cas: … 913612-38-1 …
Matched Categories: … MATE 2 Inhibitors ... Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Products: … REXULTI (BREXPIPRAZOLE) TABLETS 1 MG ... REXULTI (BREXPIPRAZOLE) TABLETS 2 MG …
Matched Salts cas: … 913612-38-1 …
Matched Categories: … MATE 2 Inhibitors ... Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Products: … REXULTI (BREXPIPRAZOLE) TABLETS 1 MG ... REXULTI (BREXPIPRAZOLE) TABLETS 2 MG …
Alfentanil
A short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.
Approved
Illicit
Matched Synonyms: … N-(1-(2-(4-Ethyl-5-oxo-2-tetrazolin-1-yl)ethyl)-4-(methoxymethyl)-4-piperidyl)propionanilide …
Matched Iupac: … N-{1-[2-(4-ethyl-5-oxo-4,5-dihydro-1H-1,2,3,4-tetrazol-1-yl)ethyl]-4-(methoxymethyl)piperidin-4-yl}-N-phenylpropanamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Rapifen 1 mg - Ampullen ... RAPIFEN 0,5 MG/ML 2 ML AMPUL, 5 ADET …
Matched Iupac: … N-{1-[2-(4-ethyl-5-oxo-4,5-dihydro-1H-1,2,3,4-tetrazol-1-yl)ethyl]-4-(methoxymethyl)piperidin-4-yl}-N-phenylpropanamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Rapifen 1 mg - Ampullen ... RAPIFEN 0,5 MG/ML 2 ML AMPUL, 5 ADET …
Displaying drugs 1976 - 2000 of 9325 in total