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Displaying drugs 2076 - 2100 of 9002 in total

Docetaxel

Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of paclitaxel.[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric...
Approved
Investigational
Matched Iupac: … }.0^{4,7}]heptadec-13-en-2-yl benzoate ... (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-(acetyloxy)-15-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy ... -3-phenylpropanoyl]oxy}-1,9,12-trihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^{3,10 …
Matched Products: … TAXESPIRA® 20 MG / 2 ML ... LILDOCEX 40 MG/ ML (80 MG/2 ML) ... DOCETAXEL 80 MG / 2 ML SOLUCION INYECTABLE …

Petrolatum

A colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.
Approved
Investigational
Matched Mixtures name: … 7 Select Hemorrhoidal Original Strength ... CARMEX Multi-Symptom 3 in 1 COLD Sore treatment External Analgesic Skin Protectant …
Matched Products: … PROVON Perineal Skin Protectant with 60% Petrolatum …

Pozelimab

CD55-deficient protein-losing enteropathy (PLE), or CHAPLE disease, is an ultra-rare hereditary disease, with fewer than 100 patients diagnosed worldwide or fewer than 10 patients in the US. The pathophysiology of this disease is mainly attributed to the deficiency of the CD55 protein, which is the main regulator of the complement...
Approved
Investigational

Allopurinol

Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints . This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals . Allopurinol is a xanthine oxidase enzyme inhibitor that...
Approved
Matched Salts cas: … 17795-21-0 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Oxamniquine

An anthelmintic with schistosomicidal activity against Schistosoma mansoni, but not against other Schistosoma spp. Oxamniquine causes worms to shift from the mesenteric veins to the liver where the male worms are retained; the female worms return to the mesentery, but can no longer release eggs. (From Martidale, The Extra Pharmacopoeia,...
Approved
Matched Iupac: … (7-nitro-2-{[(propan-2-yl)amino]methyl}-1,2,3,4-tetrahydroquinolin-6-yl)methanol …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Oxazepam

Oxazepam is an intermediate-acting, 3-hydroxybenzodiazepine used in the treatment of alcohol withdrawal and anxiety disorders. Oxazepam, like related 3-hydroxybenzodiazepine lorazepam, is considered less susceptible to pharmacokinetic variability based on patient-specific factors (e.g. age, liver disease) - this feature is advantageous as compared to other benzodiazepines, and is likely owing in...
Approved
Matched Iupac: … 7-chloro-3-hydroxy-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Description: … Oxazepam is an intermediate-acting, 3-hydroxybenzodiazepine used in the treatment of alcohol withdrawal ... Oxazepam, like related 3-hydroxybenzodiazepine [lorazepam], is considered less susceptible to pharmacokinetic …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Bromazepam

One of the benzodiazepines that is used in the treatment of anxiety disorders. It is a Schedule IV drug in the U.S. and Canada and under the Convention on Psychotropic Substances. It is a intermediate-acting benzodiazepine.
Approved
Illicit
Investigational
Matched Iupac: … 7-bromo-5-(pyridin-2-yl)-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … BROMAZANIL 3 ... LEXOTAN TABLET 3 mg ... Riva-bromazepam 3 mg …

Inosine pranobex

Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, and dimethylaminoisopropanol used as an antiviral drug.
Approved
Matched Synonyms: … Inosine-2-hydroxypropyldimethylammonium 4-acetamidobenzoate (1:3) …
Matched Iupac: … -5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one ... tris((2R)-1-(dimethylamino)propan-2-ol); tris(4-acetamidobenzoic acid); 9-[(2R,3R,4S,5R)-3,4-dihydroxy …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Ofatumumab

Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic mouse and hybridoma technology. Ofatumumab works by recognizing antigens that are expressed on the tumour cells in certain cancers; however, the antigen is...
Approved
Matched Products: … İNFÜZYONLUK ÇÖZELTİ KONSATRESİ İÇEREN FLAKON (3 ADET) …

Fludrocortisone

Fludrocortisone is a synthetic mineralocorticoid used in conjunction with hydrocortisone to replace missing endogenous corticosteroids in patients with adrenal insufficiency.[A187169,A187187] It is functionally similar to aldosterone, the body's primary endogenous mineralocorticoid, and is structurally analogous to cortisol, differing only by a fluorine atom at the 9-position of the steroid structure...
Approved
Investigational
Matched Iupac: … ,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one ... (1R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH …
Matched Salts cas: … 514-36-3 …

Ancestim

Ancestim is a non-glycosylated recombinant methionyl human stem cell factor. It is a 166 amino acid protein produced by E. coli with an amino acid sequence that is identical to the natural sequence predicted from human DNA sequence analysis, except for the addition of an N-terminal methionine . Ancestim was...
Approved
Investigational
Withdrawn

Avibactam

Avibactam is a non-β-lactam β-lactamase inhibitor that is available in combination with ceftazidime (Avycaz). This combination was approved by the FDA on February 25, 2015 for the treatment of complicated intra-abdominal infections in combination with metronidazole, and the treatment of complicated urinary tract infections, including pyelonephritis caused by antibiotic resistant-pathogens,...
Approved
Matched Iupac: … [(2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl]oxidanesulfonic acid …
Matched Mixtures name: … ZAVİCEFTA 2 G/0.5 G İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 10 ADET …

Cyclopenthiazide

Cyclopenthiazide is a thiazide diuretic with antihypertensive properties. In a double blind, randomized crossover study, cyclopenthiazide was effective in reducing diastolic blood pressure in mildly hypertensive non-insulin dependent diabetic patients . It is a positive allosteric modulator at AMPA-A receptors .
Approved
Matched Iupac: … 6-chloro-3-(cyclopentylmethyl)-1,1-dioxo-3,4-dihydro-2H-1λ⁶,2,4-benzothiadiazine-7-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Cinnarizine

First synthesized by Janssen Pharmaceuticals in 1955, cinnarizine is an anti-histaminic drug mainly used for the control of vestibular disorders and motion sickness. Cinnarizine is a specific calcium channel blocker that primarily works on the central vestibular system to interfere with the signal transmission between vestibular apparatus of the inner...
Approved
Investigational
Matched Synonyms: … 1-(Diphenylmethyl)-4-(3-phenyl-2-propenyl)piperazine …
Matched Iupac: … 1-(diphenylmethyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Salts cas: … 25332-14-3 …

Cyclandelate

A direct-acting smooth muscle relaxant used to dilate blood vessels. It may cause gastrointestinal distress and tachycardia. Cyclandelate is not approved for use in the U.S. or Canada, but is approved in various European countries.
Approved
Matched Iupac: … 3,3,5-trimethylcyclohexyl 2-hydroxy-2-phenylacetate …

Lymecycline

Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and other susceptible bacterial infections.[L13880,L13883] It has been proven a cost-effective alternative to treatment with minocycline with comparable safety and efficacy. Lymecycline was initially discovered in 1961. It is marketed by Galderma and used in the UK...
Approved
Investigational
Matched Synonyms: … dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxonaphthacene-2- ... N6-((4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2- …
Matched Iupac: … yl]formamido}methyl)amino]-2-aminohexanoic acid ... dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracen-2- …

Esketamine

Major depressive disorder (MDD) is a significant cause of disability worldwide and the most common illness preceding suicide.[L5596,A175462] On March 5, 2019, the nasal spray drug, esketamine, also known as Spravato (by Janssen Pharmaceuticals), was approved by the FDA for treatment-resistant major depression. Esketamine is the s-enantiomer of Ketamine. Ketamine...
Approved
Investigational
Matched Synonyms: … (S)-2-(o-chlorophenyl)-2-(methylamino)cyclohexanone …
Matched Iupac: … (2S)-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one …

Influenza B virus B/Phuket/3073/2013 antigen (formaldehyde inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Investigational
Matched Description: … then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. …

Sulodexide

Sulodexide is a mixture of glycosaminoglycans (GAGs) composed of dermatan sulfate (DS) and fast moving heparin (FMH).
Approved
Investigational
Matched Products: … ANJIOFLUX 600 LRU 2 ML ENJEKTABL COZELTI ICEREN 10 AMPUL …

Bethanechol

Bethanechol is a synthetic ester that was initially synthesized in 1935.[A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function to acetylcholine and is used in specific cases when stimulation of the parasympathetic nervous system is necessary.[A232905,L32539] For example, bethanechol is readily used to treat postoperative or...
Approved
Matched Synonyms: … 2-carbamoyloxypropyl-trimethylazanium ... (2-hydroxypropyl)trimethylammonium carbamate ... 2-(carbamoyloxy)-N,N,N-trimethylpropan-1-aminium …
Matched Iupac: … 1-(trimethylazaniumyl)propan-2-yl carbamate …

Halothane

A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. nitrous oxide is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required. (From AMA Drug Evaluations Annual, 1994, p178)
Approved
Vet approved
Matched Synonyms: … 1,1,1-trifluoro-2-bromo-2-chloroethane ... 1,1,1-trifluoro-2-chloro-2-bromoethane ... 2-bromo-2-chloro-1,1,1-trifluoroethane …
Matched Iupac: … 2-bromo-2-chloro-1,1,1-trifluoroethane …

Quazepam

Quazepam is a trifluoroethyl benzodiazepine derivative. It was first approved in the US in 1985 and is used as a hypnotic for the treatment of insomnia. It appears to be unique amongst other benzodiazepine derivatives in its relatively high affinity for sleep-promoting α1 subunit-containing GABAA receptors and low affinity for...
Approved
Illicit
Matched Iupac: … 7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-2,3-dihydro-1H-1,4-benzodiazepine-2-thione …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Desflurane

Desflurane, or I-653, a a volatile anesthetic that is more rapidly cleared and less metabolized than previous inhaled anesthetics such as methoxyflurane, sevoflurane, enflurane, or isoflurane.[A226390,A39015,A226893]. It was developed in the late 1980s out of a need for a more rapidly acting and rapidly cleared inhaled anesthetic.[A226883,A226888] Desflurane was granted...
Approved
Matched Synonyms: … 1,1,1,2-tetrafluoro-2-(difluoromethoxy)ethane ... (±)-2-difluoromethyl 1,2,2,2-tetrafluoroethyl ether …
Matched Iupac: … 2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane …

Estriol

A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During pregnancy, large amount of estriol is produced by the placenta. Isomers with inversion of the hydroxyl group or groups are called epiestriol. Though estriol is...
Approved
Investigational
Vet approved

Polysorbate 20

Polysorbate 20 is a polysorbate-type nonionic surfactant used in many commercial, household and pharmaceutical products. It is composed of 20 repeated units of polyethylene glycol via ethoxylation. Polysorbate 20 is a wetting agent in food products, as well as washing agent, stabilizer and solubilizer in labratory assays and industrial applications....
Approved
Displaying drugs 2076 - 2100 of 9002 in total