Displaying drugs 2101 - 2125 of 9333 in total
Amcinonide
Amcinonide is a corticosteroid.
Approved
Matched Iupac: … 2-[(1'S,2'S,4'R,8'S,9'S,11'S,12'R,13'S)-12'-fluoro-11'-hydroxy-9',13'-dimethyl-16'-oxo-5',7'-dioxaspiro ... [cyclopentane-1,6'-pentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane]-14',17'-dien-8'-yl]-2-oxoethyl …
Cysteamine
Cystinosis is a rare disease caused by mutations in the CTNS gene that encodes for cystinosin, a protein responsible for transporting cystine out of the cell lysosome. A defect in cystinosin function is followed by cystine accumulation throughout the body, especially the eyes and kidneys. Several preparations of cysteamine exist...
Approved
Investigational
Matched Synonyms: … 2-amino-1-ethanethiol ... 2-aminoethanethiol ... 2-amino-ethanethiol …
Matched Iupac: … 2-aminoethane-1-thiol …
Matched Iupac: … 2-aminoethane-1-thiol …
Dexamethasone acetate
Commonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions.[T797,L10695,L14348] Developed in 1957, dexamethasone is structurally similar to other corticosteroids such as hydrocortisone and prednisolone. Dexamethasone acetate has largely been replaced by dexamethasone phosphate and...
Approved
Investigational
Vet approved
Matched Iupac: … ,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate ... 2-[(1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-2,9a,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH …
Matched Mixtures name: … DUODECADRON ® SUSPENSIÓN INYECTABLE 1 ML ... DUODECADRON ® SUSPENSIÓN INYECTABLE 1 ML ... CLOTRIMAZOL 1% +NEOMICINA 0.5% + DEXAMETASONA 0.04% CREMA …
Matched Mixtures name: … DUODECADRON ® SUSPENSIÓN INYECTABLE 1 ML ... DUODECADRON ® SUSPENSIÓN INYECTABLE 1 ML ... CLOTRIMAZOL 1% +NEOMICINA 0.5% + DEXAMETASONA 0.04% CREMA …
Influenza A virus A/Kansas/14/2017 X-327 (H3N2) antigen (propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Triethylenetetramine
Triethylenetatramine (TETA), also known as trientine, is a potent and selective copper (II)-selective chelator. It is a structural analog of linear polyamine compounds, spermidine and spermine. TETA was first developed in Germany in 1861 and its chelating properties were first recognized in 1925. Initially approved by the FDA in 1985...
Approved
Investigational
Matched Iupac: … (2-aminoethyl)({2-[(2-aminoethyl)amino]ethyl})amine …
Dyclonine
Dyclonine is an oral anaesthetic found in Sucrets, an over the counter throat lozenge. It may also be found in some Cepacol sore throat spray products.
Approved
Matched Synonyms: … 2-(1-piperidyl)ethyl p-butoxyphenyl ketone ... 1-(4-Butoxyphenyl)-3-(1-piperidinyl)-1-propanone ... 4-n-butoxy-β-(1-piperidyl)propiophenone …
Matched Iupac: … 1-(4-butoxyphenyl)-3-(piperidin-1-yl)propan-1-one …
Matched Iupac: … 1-(4-butoxyphenyl)-3-(piperidin-1-yl)propan-1-one …
Acenocoumarol
Acenocoumarol is a coumarin derivative used as an anticoagulant. Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes with coagulation. Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. Patients...
Approved
Investigational
Matched Synonyms: … 4-Hydroxy-3-(1-(4-nitrophenyl)-3-oxobutyl)-2H-1-benzopyran-2-one ... 4-Hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one …
Matched Iupac: … 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Tegaserod
Novartis' brand name Zelnorm (tegaserod) had originally received approval from the US FDA in 2002 for the treatment of irritable bowel syndrome with constipation (IBS-C).[L5918,F4229] It was, however, voluntarily withdrawn from widespread use in the US market in 2007 after concerns arose over the possibility that tegaserod could potentially cause...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-(((5-Methoxyindol-3-yl)methylene)amino)-3-pentylguanidine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Doravirine
Doravirine is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) intended to be administered in combination with other antiretroviral medicines.[L12729,L4562] Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and tenofovir disoproxil fumarate (300 mg). Doravirine is formally indicated for the treatment of...
Approved
Investigational
Matched Iupac: … 3-chloro-5-({1-[(4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl]-2-oxo-4-(trifluoromethyl)-1,2 …
Matched Description: … Doravirine is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) intended to be administered ... [L4562] Doravirine is formally indicated for the treatment of HIV-1 infection in adult patients with ... expanding the possibility and choice of therapeutic treatments available for the management of HIV-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor …
Matched Description: … Doravirine is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) intended to be administered ... [L4562] Doravirine is formally indicated for the treatment of HIV-1 infection in adult patients with ... expanding the possibility and choice of therapeutic treatments available for the management of HIV-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor …
Spironolactone
Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered.[A11837, A178246] It is indicated to treat several conditions, including...
Approved
Matched Iupac: … )-9a,11a-dimethyl-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydrospiro[cyclopenta[a]phenanthrene-1,2 …
Matched Mixtures name: … Benzoyl Peroxide 5% / Clindamycin 1% / Niacinamide 2% / Spironolactone 2% ... Benzoyl Peroxide 5% / Clindamycin 1% / Niacinamide 2% / Spironolactone 2% / Tretinoin 0.05% ... Benzoyl Peroxide 5% / Clindamycin 1% / Niacinamide 2% / Spironolactone 2% / Tretinoin 0.025% …
Matched Mixtures name: … Benzoyl Peroxide 5% / Clindamycin 1% / Niacinamide 2% / Spironolactone 2% ... Benzoyl Peroxide 5% / Clindamycin 1% / Niacinamide 2% / Spironolactone 2% / Tretinoin 0.05% ... Benzoyl Peroxide 5% / Clindamycin 1% / Niacinamide 2% / Spironolactone 2% / Tretinoin 0.025% …
Cloxacillin
A semi-synthetic penicillin antibiotic which is a chlorinated derivative of oxacillin.
Approved
Investigational
Vet approved
Matched Synonyms: … (2S,5R,6R)-6-({[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1- ... azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … (2S,5R,6R)-6-[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo ... [3.2.0]heptane-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (2S,5R,6R)-6-[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo ... [3.2.0]heptane-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Berdazimer
Berdazimer is a polymeric substance consisting of a polysiloxane backbone (Si-O-Si bonds) with covalently bound N-diazeniumdiolate nitric oxide (NO) donors. It releases NO through exposure to proton donors like water, which will degrade the N-diazeniumdiolate entity. Berdazimer was previously investigated as a potential treatment for molluscum contagiosum, a viral cutaneous...
Approved
Matched Synonyms: … Silsesquioxanes, 3-(2-hydroxy-1-methyl-2-nitrosohydrazinyl)propyl 3-(methylamino)propyl, polymers with …
Matched Description: … 2, where reduced lesion counts were observed with once-a-day uses of berdazimer. ... This decision is based on positive results demonstrated in 2 Phase 3 trials, B-SIMPLE 4 and B-SIMPLE …
Matched Salts cas: … 1846565-00-1 …
Matched Description: … 2, where reduced lesion counts were observed with once-a-day uses of berdazimer. ... This decision is based on positive results demonstrated in 2 Phase 3 trials, B-SIMPLE 4 and B-SIMPLE …
Matched Salts cas: … 1846565-00-1 …
Glycopyrronium
Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers. They are both quaternary ammonium compounds and long acting muscarinic antagonists. It is one of the most commonly prescribed anticholinergic medications.[A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the...
Approved
Investigational
Vet approved
Matched Iupac: … 3-[(2-cyclopentyl-2-hydroxy-2-phenylacetyl)oxy]-1,1-dimethylpyrrolidin-1-ium …
Matched Salts cas: … 1624259-25-1 …
Matched Categories: … MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring …
Matched Salts cas: … 1624259-25-1 …
Matched Categories: … MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring …
Diphenhydramine
Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and stings, and rashes [L5263, L5266, L5269, F3379]. However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269,...
Approved
Investigational
Matched International brands: … Dormarex 2 …
Matched Synonyms: … 2-(benzhydryloxy)-N,N-dimethylethylamine ... 2-diphenylmethoxy-N,N-demthylethanamine ... α-(2-dimethylaminoethoxy)diphenylmethane …
Matched Iupac: … [2-(diphenylmethoxy)ethyl]dimethylamine …
Matched Salts cas: … 31065-89-1 …
Matched Mixtures name: … Adventure Medical Kits 1-2 Person First Aid ... DIFESTOL %1.2+%2 JEL ... Adventure Medical Kits 1-4 Person First Aid …
Matched Products: … Benadryl Cream 2% ... FENOTRAL JEL %2, 30 G ... ALLENIK 20 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ, 100 AMPUL …
Matched Synonyms: … 2-(benzhydryloxy)-N,N-dimethylethylamine ... 2-diphenylmethoxy-N,N-demthylethanamine ... α-(2-dimethylaminoethoxy)diphenylmethane …
Matched Iupac: … [2-(diphenylmethoxy)ethyl]dimethylamine …
Matched Salts cas: … 31065-89-1 …
Matched Mixtures name: … Adventure Medical Kits 1-2 Person First Aid ... DIFESTOL %1.2+%2 JEL ... Adventure Medical Kits 1-4 Person First Aid …
Matched Products: … Benadryl Cream 2% ... FENOTRAL JEL %2, 30 G ... ALLENIK 20 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ, 100 AMPUL …
Tazemetostat
Tazemetostat is a methyltransferase inhibitor used to treat metastatic or locally advanced epithelioid sarcoma not eligible for complete resection. Tazemetostat was first named in literature as EPZ-6438. Tazemetaostat was granted FDA approval on 23 January 2020.
Approved
Investigational
Matched Iupac: … N-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-5-[ethyl(oxan-4-yl)amino]-4-methyl-4'-[(morpholin …
Matched Categories: … MATE 1 Inhibitors ... MATE 2 Inhibitors ... MATE 2-K Inhibitors ... Heterocyclic Compounds, 1-Ring …
Matched Categories: … MATE 1 Inhibitors ... MATE 2 Inhibitors ... MATE 2-K Inhibitors ... Heterocyclic Compounds, 1-Ring …
Influenza A virus A/Victoria/361/2011 IVR-165 (H3N2) antigen (propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Influenza A virus A/Victoria/361/2011 IVR-165 (H3N2) antigen (UV, formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Podofilox
A lignan found in podophyllin resin from the roots of podophyllum plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and...
Approved
Matched Iupac: … hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8- …
Coenzyme M
Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.
Approved
Investigational
Matched Synonyms: … 2-Mercaptoethane ... 2-Mercaptoethanesulfonate ... 2-mercaptoethylsulfonate …
Matched Iupac: … 2-sulfanylethane-1-sulfonic acid …
Matched Iupac: … 2-sulfanylethane-1-sulfonic acid …
Poloxamer 188
Poloxamer 188 (P188) is a nonionic block linear copolymer that exhibits rheologic, anti-thrombotic, anti-inflammatory, and cytoprotective activities in various tissue injury models . Composed of two hydrophilic side-chains attached to a hydrophobic center core , its average molecular weight is 8400 Daltons. P188 was originally approved by the FDA in...
Approved
Investigational
Insulin glargine
Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … and Type 2 Diabetes. ... Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 ... Insulin is also used in the treatment of Type 2 Diabetes (T2D), another form of diabetes mellitus that …
Matched Products: … LANTUS 100 IU/ML SUBKUTAN KULLANIM İÇİN ENJEKSİYONLUK SOLÜSYON, 1 ADET ... BASAGLAR KWIKPEN 100 U/ML SC KULLANIM ICIN ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR KALEM, 2 ADET …
Matched Products: … LANTUS 100 IU/ML SUBKUTAN KULLANIM İÇİN ENJEKSİYONLUK SOLÜSYON, 1 ADET ... BASAGLAR KWIKPEN 100 U/ML SC KULLANIM ICIN ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR KALEM, 2 ADET …
Sulfamerazine
A sulfanilamide that is used as an antibacterial agent.
Approved
Vet approved
Matched Synonyms: … N(1)-(4-Methyl-2-pyrimidinyl)sulfanilamide ... 2-Sulfa-4-methylpyrimidine ... 2-(Sulfanilamido)-4-methylpyrimidine …
Matched Iupac: … 4-amino-N-(4-methylpyrimidin-2-yl)benzene-1-sulfonamide …
Matched Salts cas: … 127-58-2 …
Matched Iupac: … 4-amino-N-(4-methylpyrimidin-2-yl)benzene-1-sulfonamide …
Matched Salts cas: … 127-58-2 …
Linaclotide
Linaclotide is a synthetic 14-amino acid cyclic peptide and first-in-class guanylate cyclase-C (G-CC) agonist.[A260271, L47211] Linaclotide is structurally related to human guanylin and uroguanylin, paracrine peptide hormones that are endogenous activators of GC-C. It is also a homolog of a heat-stable enterotoxin derived from Escherichia coli, the first natural ligand...
Approved
Matched Synonyms: … >6),(2->10),(5->13)-TRIS(DISULFIDE) ... GLUTAMYL-L-TYROSYL-L-CYSTEINYL-L-CYSTEINYL-L-ASPARAGINYL-L-PROLYL-L-ALANYL-L-CYSTEINYL-L-THREONYLGLYCYL-L-CYSTEINYL-, CYCLIC (1- …
Matched Iupac: … (2S)-2-{[(1R,4S,7S,13S,16R,21R,24R,27S,30S,33R,38R,44S)-21-amino-13-(carbamoylmethyl)-27-(2-carboxyethyl ... )-44-[(1R)-1-hydroxyethyl]-30-[(4-hydroxyphenyl)methyl]-4-methyl-3,6,12,15,22,25,28,31,40,43,46,51-dodecaoxo …
Matched Iupac: … (2S)-2-{[(1R,4S,7S,13S,16R,21R,24R,27S,30S,33R,38R,44S)-21-amino-13-(carbamoylmethyl)-27-(2-carboxyethyl ... )-44-[(1R)-1-hydroxyethyl]-30-[(4-hydroxyphenyl)methyl]-4-methyl-3,6,12,15,22,25,28,31,40,43,46,51-dodecaoxo …
Olodaterol
Olodaterol is a novel, long-acting beta2-adrenergic agonist (LABA) that exerts its pharmacological effect by binding and activating beta2-adrenergic receptors located primarily in the lungs. Beta2-adrenergic receptors are membrane-bound receptors that are normally activated by endogenous epinephrine whose signalling, via a downstream L-type calcium channel interaction, mediates smooth muscle relaxation and...
Approved
Matched Iupac: … 6-hydroxy-8-[(1R)-1-hydroxy-2-{[1-(4-methoxyphenyl)-2-methylpropan-2-yl]amino}ethyl]-3,4-dihydro-2H-1,4 …
Matched Description: … Single doses of olodaterol have been shown to improve forced expiratory volume in 1 sec (FEV1) for 24 …
Matched Mixtures name: … SPIOLTO RESPIMAT 2.5 MCG/2.5 MCG INHALASYON ÇÖZELTISI,1 ADET …
Matched Categories: … Adrenergic beta-1 Receptor Agonists ... Heterocyclic Compounds, 1-Ring ... Adrenergic beta-2 Receptor Agonists ... Heterocyclic Compounds, 2-Ring ... Selective Beta 2-adrenergic Agonists …
Matched Description: … Single doses of olodaterol have been shown to improve forced expiratory volume in 1 sec (FEV1) for 24 …
Matched Mixtures name: … SPIOLTO RESPIMAT 2.5 MCG/2.5 MCG INHALASYON ÇÖZELTISI,1 ADET …
Matched Categories: … Adrenergic beta-1 Receptor Agonists ... Heterocyclic Compounds, 1-Ring ... Adrenergic beta-2 Receptor Agonists ... Heterocyclic Compounds, 2-Ring ... Selective Beta 2-adrenergic Agonists …
Glipizide
Glipizide is an oral hypoglycemic agent in the second-generation sulfonylurea drug class that is used to control blood sugar levels in patients with type 2 diabetes mellitus. It was first introduced in 1984 and is available in various countries including Canada and the U.S. According to the 2018 Clinical Practice...
Approved
Investigational
Matched Synonyms: … 1-cyclohexyl-3-({p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl}sulfonyl)urea ... N-{4-[β-(5-methylpyrazine-2-carboxamido)ethyl]benzenesulphonyl}-N'-cyclohexylurea …
Matched Iupac: … N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-5-methylpyrazine-2-carboxamide …
Matched Description: … second-generation sulfonylurea drug class that is used to control blood sugar levels in patients with type 2 ... cells for their therapeutic effectiveness, sulfonylureas are more commonly used for early-stage type 2 …
Matched Iupac: … N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-5-methylpyrazine-2-carboxamide …
Matched Description: … second-generation sulfonylurea drug class that is used to control blood sugar levels in patients with type 2 ... cells for their therapeutic effectiveness, sulfonylureas are more commonly used for early-stage type 2 …
Displaying drugs 2101 - 2125 of 9333 in total