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Displaying drugs 2201 - 2225 of 9608 in total
Gallium citrate Ga-67
Gallium citrate Ga 67 is the citrate salt of the radioisotope gallium Ga 67. Although the mechanism is unknown, gallium Ga 67 concentrates in lysosomes and is bound to a soluble intracellular protein in certain viable primary and metastatic tumors and focal sites of inflammation, allowing scintigraphic localization. Ga-67 scintigraphy...
Approved
Matched Description: … Gallium citrate Ga 67 is the citrate salt of the radioisotope gallium Ga 67. ... to a soluble intracellular protein in certain viable primary and metastatic tumors and focal sites of …
Beeswax
The wax obtained from the honeycomb of the bee. It consists primarily of myricyl palmitate, cerotic acid esters and some high-carbon paraffins. Beeswax is used as a stiffening agent in ointments and creams, and enables water to be incorporated to produce water-in-oil emulsions. It is also used as a coating...
Approved
Matched Description: … The wax obtained from the honeycomb of the bee. ... It is also used as a coating in the manufacture of modified-release oral preparations ... It consists primarily of myricyl palmitate, cerotic acid esters and some high-carbon paraffins. …
Quaternium-15
Quaternium-15 is a quaternary ammonium salt used as a surfactant and preservative in many products including cosmetics. It is an anti-microbial agent by virtue of being a formaldehyde releaser, however this can also cause contact dermatitis, a symptom of an allergic reaction, especially in those with sensitive skin. In 2005,...
Approved
Experimental
Matched Description: … contact dermatitis, a symptom of an allergic reaction, especially in those with sensitive skin. ... It is an anti-microbial agent by virtue of being a formaldehyde releaser, however this can also cause …
Pegulicianine
Pegulicianine is an optical imaging agent indicated for fluorescence imaging in patients with breast cancer. It is used following surgical resection of the primary tumor to detect areas of remaining cancer. Pegulicianine itself is a prodrug comprising three main fragments, one of which contains a fluorescence quencher that keeps the...
Approved
Matched Description: … It is used following surgical resection of the primary tumor to detect areas of remaining cancer. ... Pegulicianine itself is a prodrug comprising three main fragments, one of which contains a fluorescence ... [L50537] The _in vivo_ enzymatic cleavage of pegulicianine results in two optically active fragments …
Dinoprost tromethamine
The tromethamine (THAM) salt of the naturally occurring prostaglandin F2 alpha, dinoprost tromethamine occurs as a white to off-white, very hygroscopic, crystalline powder. Dinoprost tromethamine may also be known as dinoprost trometamol, PGF2 alpha THAM, or prostaglandin F2 alpha tromethamine.
Approved
Vet approved
Matched Description: … The tromethamine (THAM) salt of the naturally occurring prostaglandin F2 alpha, dinoprost tromethamine …
Ambrisentan
Ambrisentan is an orally active selective type A endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension. It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ability and delay clinical worsening. In addition, it is approved in the...
Approved
Investigational
Matched Description: … Ambrisentan is an orally active selective type A endothelin receptor antagonist indicated for the treatment of ... Patients studied displayed symptoms and etiologies predominantly of WHO Functional Class II-III. ... Studies establishing the efficacy of Ambrisentan included patients with both idiopathic or heritable …
Tofacitinib
Tofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function. It is approved by the FDA for treatment of moderate to severe rheumatoid arthritis that responds inadequately to methotrexate or in those who are intolerant to methotrexate....
Approved
Investigational
Matched Description: … Tofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling ... organ transplant rejection, and is currently under investigation for the treatment of psoriasis. ... Besides rheumatoid arthritis, tofacitinib has also been studied in clinical trials for the prevention of …
Influenza A virus A/California/7/2009 (H1N1) recombinant hemagglutinin antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … memory B cells) and of cell-mediated immunity through the production of T-lymphocytes. ... This defence includes the production of humoral immunity through the development of antibodies (through ... A seasonally-specific component of the influenza vaccine. …
Necitumumab
Necitumumab is an intravenously administered recombinant monoclonal IgG1 antibody used in the treatment of non-small cell lung cancer (NSCLC) as an EGFR antagonist. It functions by binding to epidermal growth factor receptor (EGFR) and prevents binding of its ligands, a process that is involved in cell proliferation, metastasis, angiogenesis, and...
Approved
Investigational
Matched Description: … activation of EGFR which is beneficial in NSCLC as many patients have increased protein expression of ... Necitumumab is an intravenously administered recombinant monoclonal IgG1 antibody used in the treatment of ... It functions by binding to epidermal growth factor receptor (EGFR) and prevents binding of its ligands …
Isoetharine
Isoetharine is a relatively selective beta-2 adrenergic agonist. It is a catechol-like agent. Isoetharine is a fast-acting bronchodilator used for emphysema, bronchitis and asthma.
Approved
Phenacemide
Phenacemide is used to control certain seizures in the treatment of epilepsy. This medicine acts on the central nervous system (CNS) to reduce the number and severity of seizures.
Approved
Matched Description: … Phenacemide is used to control certain seizures in the treatment of epilepsy. ... This medicine acts on the central nervous system (CNS) to reduce the number and severity of seizures. …
Acacia dealbata pollen
Acacia dealbata pollen allergenic extract is used in allergenic testing.
Approved
2,2'-Dibenzothiazyl disulfide
2,2'-Dibenzothiazyl disulfide is an accelerator used in the processing process for natural and synthetic rubber and plastic regeneration. It is also a known allergen and dermatological sensitizer.
Sensitivity to 2,2'-Dibenzothiazyl disulfide may be identified with a clinical patch test.
Approved
Experimental
Antipyrine
An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
Approved
Investigational
Matched Description: … Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes …
Cabozantinib
Cabozantinib was first approved in 2012 and is a non-specific tyrosine kinase inhibitor. It was initially approved in the US under the brand name Cometriq, which is indicated for the treatment of metastatic medullary thyroid cancer. In 2016, a capsule formulation (Cabometyx) was approved for the treatment of advanced renal...
Approved
Investigational
Matched Description: … was initially approved in the US under the brand name Cometriq, which is indicated for the treatment of ... [L15123] In 2016, a capsule formulation (Cabometyx) was approved for the treatment of advanced renal ... this same formulation gained additional approval in both the US and Canada in 2019 for the treatment of …
Cinnamaldehyde
Cinnamaldehyde is a naturally occurring flavonoid that gives the spice cinnamon its flavour and odour. It occurs naturally in the bark of cinnamon trees and other species of the genus Cinnamomum such as camphor and cassia.
Sensitivity to cinnamaldehyde may be identified with a clinical patch test.
Approved
Experimental
Matched Description: … It occurs naturally in the bark of cinnamon trees and other species of the genus Cinnamomum such as camphor …
Isoeugenol
Isoeugenol is a commonly used fragrance added to many commercially available products, and occurs naturally in the essential oils of plants such as ylang-ylang. It is also a significant dermatologic sensitizer and allergen, and as a result has been restricted to 200 p.p.m. since 1998 according to guidelines issued by...
Approved
Experimental
Matched Description: … fragrance added to many commercially available products, and occurs naturally in the essential oils of …
Carteolol
A beta-adrenergic antagonist used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and an antiglaucoma agent.
Approved
Pyrvinium
Pyrvinium is an anthelmintic effective for pinworms. Several forms of pyrvinium have been prepared with variable counter anions, such as halides, tosylate, triflate and pamoate. Pyrvinum's anti-cancer properties are currently under investigation.
Approved
Matched Description: … Several forms of pyrvinium have been prepared with variable counter anions, such as halides, tosylate …
Helium
Helium is a second most abundant chemical element in the universe with symbol He and atomic number 2. It is a colorless, odorless, tasteless, non-toxic, inert, monatomic gas located at the top of the noble gases on the periodic table. Its boiling and melting points are the lowest among all...
Approved
Investigational
Vet approved
Matched Description: … It is a colorless, odorless, tasteless, non-toxic, inert, monatomic gas located at the top of the noble ... It is also used as an analytical reagent in diagnostic/imaging tests to detect respiratory function of …
Potassium cation
Potassium is the major cation (positive ion) inside animal cells, while sodium is the major cation outside animal cells. The concentration differences of these charged particles causes a difference in electric potential between the inside and outside of cells, known as the membrane potential. The balance between potassium and sodium...
Approved
Investigational
Matched Description: … the inside and outside of cells, known as the membrane potential. ... The concentration differences of these charged particles causes a difference in electric potential between ... Potassium is also an essential mineral needed to regulate water balance, blood pressure and levels of …
Anethole trithione
Anethole trithione (ATT) appears to have a broad range of unique functions, from increasing salivary secretion to help treat xerostomia [A27165, A32618, A32620, A32621], to demonstrating an ability to inhibit carcinogenesis by increasing the activity of electrophile detoxification enzymes , and even being used as an adjunctive therapy for cholecystitis,...
Approved
Experimental
Matched Description: … Unfortunately, many of the specific mechanisms of action to these activities have yet to be formally ... Anethole trithione (ATT) appears to have a broad range of unique functions, from increasing salivary ... , A32620, A32621], to demonstrating an ability to inhibit carcinogenesis by increasing the activity of …
Stearic acid
Stearic acid (IUPAC systematic name: octadecanoic acid) is one of the useful types of saturated fatty acids that comes from many animal and vegetable fats and oils. It is a waxy solid.
Approved
Experimental
Matched Description: … Stearic acid (IUPAC systematic name: octadecanoic acid) is one of the useful types of saturated fatty …
Oxyphenisatin acetate
Oxyphenisatin acetate is the pro-drug of oxyphenisatin (3,3-bis(4-hydroxyphenyl)-1H-indol-2-one). The FDA withdrew its approval for the use of oxyphenisatin acetate due to safety reasons.
Approved
Investigational
Withdrawn
Matched Description: … Oxyphenisatin acetate is the pro-drug of [oxyphenisatin] (3,3-bis(4-hydroxyphenyl)-1H-indol-2-one). ... The FDA withdrew its approval for the use of oxyphenisatin acetate due to safety reasons.[L43942] …
Formaldehyde
A highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons. In solution, it has a wide range of uses: in the manufacture of resins and textiles, as a disinfectant, and as a laboratory fixative or preservative. Formaldehyde solution (formalin) is considered a hazardous compound, and its vapor...
Approved
Vet approved
Matched Description: … In solution, it has a wide range of uses: in the manufacture of resins and textiles, as a disinfectant ... A highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons. …
Displaying drugs 2201 - 2225 of 9608 in total