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Displaying drugs 201 - 225 of 10999 in total
Pucotenlimab is a recombinant humanized anti-PD-1 monoclonal antibody. It received its first global approval in China in July 2022 for the treatment of solid tumours. It is being investigated in other cancers.
Approved
Investigational
Matched Synonyms: … proline,432-alanine), anti-(human programmed cell death 1) (human-mus musculus monoclonal hx008 .gamma.4- …
A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed) The FDA withdrew its...
Approved
Investigational
Withdrawn
Matched Synonyms: … (E)-3,4-bis(4-hydroxyphenyl)-3-hexene …
Matched Iupac: … 4-[(3E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol …
An antiarrhythmia agent used primarily for ventricular rhythm disturbances.
Approved
Investigational
Withdrawn
Matched Synonyms: … [10-(3-Morpholin-4-yl-propionyl)-10H-phenothiazin-2-yl]-carbamic acid ethyl ester …
Matched Iupac: … ethyl N-{10-[3-(morpholin-4-yl)propanoyl]-10H-phenothiazin-2-yl}carbamate …
Matched Salts cas: … 29560-58-5
Mepyramine, or pyrilamine, targets the H1 receptor. It is a first generation antihistamine. However, it rapidly permeates the brain and so often causes drowsiness as a side effect. It has been found in over-the-counter combination products for colds and menstrual symptoms, but is considered to be an unapproved prescription medication...
Approved
Vet approved
Matched Synonyms: … N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-1,2-ethanediamine …
Matched Iupac: … N-[2-(dimethylamino)ethyl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine …
Matched Salts cas: … 59-33-6
Matched Mixtures name: … SOLERAT %5+%1,5+%1,5 JEL ... STILEX %1,5 + %1,5 + %5 JEL, 30 G ... STIDERM %1.5 / %1.5 / %5 JEL ,30 G …
First generation histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. It is a component of cough and cold medicines. It may cause drowsiness.
Approved
Matched Synonyms: … trans-1-(4-methylphenyl)-1-(2-pyridyl)-3-pyrrolidinoprop-1-ene …
Matched Iupac: … 2-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridine …
Matched Salts cas: … 550-70-9
Matched Mixtures name: … ACTİFED 30 MG/5 ML + 1,25 MG/5 ML ŞURUP ... PEACEF SYRUP 30 mg/5 ml …
Methylprednisolone is a prednisolone derivative glucocorticoid with higher potency than prednisone. It was first described in the literature in the late 1950s.[A188811,A188814] Methylprednisolone was granted FDA approval on 24 October 1957. In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with...
Approved
Vet approved
Matched Synonyms: … (6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione …
Matched Products: … DEPO-MEDROL 40 MG / MLSUSPENSIONINYECTABLEX 5 ML ... XILON 4 ... METTY 4
An alkaloid found in the root of Rauwolfia serpentina, among other plant sources. It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials. Ajmaline produces potent sodium channel blocking effects and a very short half-life which makes it a very...
Approved
Experimental
Matched Synonyms: … (5aR,6S,8S,10S,11S,11aS,12aR,13R)-5-methyl-5a,6,8,9,10,11,11a,12-octahydro-5H-6,10:11,12a-dimethanoindolo …
Matched Products: … Gilurytmal 5 mg/ml Injektionslösung und Konzentrat zur Herstellung einer Infusionslösung …
A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties. Having been developed in the 1980s by GlaxoSmithKline and approved by the US FDA since January 1991, ondansetron has...
Approved
Withdrawn
Matched Iupac: … 9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-2,3,4,9-tetrahydro-1H-carbazol-4-one …
Matched Salts cas: … 99614-01-4 ... 103639-04-9
Matched Categories: … Serotonin 5-HT3 Receptor Antagonists ... Antiemetic Serotonin 5-HT3 Receptor Antagonists …
Matched Products: … KEMOSET 4 MG FILM TABLET, 6 ADET ... ZOFRAN 4 MG FILM TABLET, 6 ADET ... ZONTRON 4 MG FILM TABLET (6 TABLET) …
Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions. Developed in 1957, it is structurally similar to other corticosteroids like hydrocortisone and prednisolone. Dexamethasone was granted FDA approval on 30 October 1958....
Approved
Investigational
Vet approved
Matched Description: … Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic …
Matched Salts cas: … 312-93-6 ... 2392-39-4
Matched Mixtures name: … R-DIM® ... GOTABIOTIC(R)F OFTALMICO ... NETİZON 5 MG+15 MG/5 ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET …
Matched Products: … HiDex 6-day ... TaperDex 6-day ... DEXAMETHASONE 6-Day …
A synthetic progestational hormone with no androgenic or estrogenic properties. Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit ovulation.
Approved
Investigational
Withdrawn
Matched Synonyms: … delta(6)-Retroprogesterone ... 6-Dehydro-retro-progesterone ... Retro-6-dehydroprogesterone …
Matched Mixtures name: … FEMOSTON CONTI 1/5 ... FEMOSTON CONTI 1/5 TABLET ... Femoston conti 1 mg/5 mg Filmtabletten …
An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Approved
Investigational
Matched Synonyms: … 9-[(dimethylamino)methyl]-10-hydroxy-(4S)-camptothecin …
Matched Iupac: … ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1(21),2,4(9) …
Matched Salts cas: … 119413-54-6
Matched Products: … TOPOTU 4MG/4ML KONSANTRE INFÜZYON ÇÖZELTISI, 5 FLAKON ... HYCAMTIN IV LİYOFİLİZE TOZ İÇEREN ENJEKTABL FLAKON, 5 ADET ... TOPOTECAN 4 MG …
Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched Synonyms: … (R-(E))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl ... 1-[[[(1 R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl] phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl] …
Matched Mixtures name: … LEVMONT 2.5/4 MG CIGNEME TABLET, 90 ADET ... LEVMONT 2.5/4 MG TOZ İÇEREN SAŞE, 90 ADET ... AIRCOMB 2,5 MG/4 MG GRANÜL İÇEREN SAŞE, 30 ADET …
Matched Products: … Spirant 5 Chewable (Montelukast sodium tablets 5 mg) ... MONAST 5 (Montelukast Paediatric Chewable Tablets 5 mg) ... LEUTRIEN® 5 MG …
Paclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others. Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel. It is available as...
Approved
Vet approved
Matched Synonyms: … 5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate ... -12-(BENZOYLOXY)-2A,3,4,4A,5,6,9,10,11,12,12A,12B-DODECAHYDRO-4,11-DIHYDROXY-4A,8,13,13-TETRAMETHYL-5- …
Matched Iupac: … dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6- …
Matched Products: … LILPACLI 6 MG/ ML (30 MG / 5 ML) ... PAXEL INJECTION 6 mg/ml ... AZEC 30 MG/5 ML …
Silodosin is a selective antagonist of alpha(α)-1 adrenergic receptors that binds to the α1A subtype with the highest affinity. α1-adrenergic receptors regulate smooth muscle tone in the bladder neck, prostate, and prostatic urethra: the α1A subtype accounts for approximately 75% of α1-adrenoceptors in the prostate. Silodosin was first approved by...
Approved
Matched Iupac: … 1-(3-hydroxypropyl)-5-[(2R)-2-({2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl}amino)propyl]-2,3-dihydro-1H-indole …
Matched Products: … ซิโดรี 4 ... URIEF TABLETS 4 MG ... FENANTA® 4 MG …
Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections.[A181036,A181039] Metronidazole has been used as an antibiotic for several decades , with added antiparasitic properties that set...
Approved
Matched Synonyms: … 2-methyl-3-(2-hydroxyethyl)-4-nitroimidazole ... 2-methyl-5-nitroimidazole-1-ethanol ... 1-(β-oxyethyl)-2-methyl-5-nitroimidazole …
Matched Iupac: … 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethan-1-ol …
Matched Mixtures name: … MIKIUM(R) OVULOS ... Metronidazole 1% / Niacinamide 4% ... Ivermectin 1% / Metronidazole 1% / Niacinamide 4% …
Matched Products: … AMEFAR(R) TABLETA VAGINAL500 MG ... Braun 5 mg/ml Infusionslösung ... AMEFAR® 250 MG / 5 ML SUSPENSION …
Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Investigational
Matched Mixtures name: … BONEPLUS D3 75 MG/2800 IU EFERVESAN TABLET, 6 ADET ... RISEPLUS D3 75 MG/5600 IU EFERVESAN TABLET, 6 ADET ... RISEPLUS TEDAVI PAKETİ, 4+24 ADET …
Matched Products: … ACTONEL 75 MG FILM KAPLI TABLET, 6 ADET ... BONEPLUS 75 MG EFERVESAN TABLET, 6 ADET ... ACTONEL TABLET 5 mg …
Apomorphine is a non-ergoline dopamine D2 agonist indicated to treat hypomobility associated with Parkinson's. It was first synthesized in 1845 and first used in Parkinson's disease in 1884. Apomorphine has also been investigated as an emetic, a sedative, a treatment for alcoholism, and a treatment of other movement disorders.[A203597,A203618] Apomorphine...
Approved
Investigational
Matched Synonyms: … (R)-5,6,6a,7-tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol ... R-(−)-apomorphine ... (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Matched Products: … VERAPOMOR 50 MG/5 ML ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ, 5 ADET ... PARGYCIL 50 MG/ 5 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPÜL, 5 ADET ... DOPAMOR 50 MG/5 ML ENJEKSİYONLUK VEYA İNFÜZYONLUK ÇÖZELTİ, 5 ADET …
Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Approved
Investigational
Matched Synonyms: … (+)-(R)-2-(alpha-(2-(Diisopropylamino)ethyl)benzyl)-p-cresol …
Matched Iupac: … 2-[(1R)-3-[bis(propan-2-yl)amino]-1-phenylpropyl]-4-methylphenol …
Matched Salts cas: … 124937-52-6
Matched Products: … TEROCYS-4 ... TEROTOL 4 MG ... DETRUSITOL RETARD 4 MG …
Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is administered orally as the prodrug, candesartan cilexetil, which is rapidly converted to its active metabolite, candesartan, during absorption in the gastrointestinal tract. Candesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone...
Approved
Matched Iupac: … 1-{[(cyclohexyloxy)carbonyl]oxy}ethyl 2-ethoxy-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl …
Matched Mixtures name: … UNISIA 8 MG/5 MG ... UNISIA 8 MG/5 MG ... CANDAM ® H 5/32/12.5 …
Matched Products: … Atacand 4 mg - Tabletten ... Blopress 4 mg - Tabletten ... ATACAND TABLET 4 mg …
Lacidipine is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex tachycardia . It displays specificity in the vascular smooth muscle, where it acts as an antihypertensive agent to dilate peripheral arterioles and reduce...
Approved
Investigational
Matched Iupac: … 3,5-diethyl 4-{2-[(1E)-3-(tert-butoxy)-3-oxoprop-1-en-1-yl]phenyl}-2,6-dimethyl-1,4-dihydropyridine-3,5 …
Matched Description: … In randomised, well-controlled trials, administration of daily single-dose lacidipine ranging from 2-6 ... It is available as once-daily oral tablets containing 2 or 4 mg of the active compound commonly marketed …
Matched Products: … LACIPIL TABLET 4 mg ... LACIPIL 4 MG TABLET, 28 ADET ... LACIPIL 4 MG FILM TABLET, 14 ADET …
A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Approved
Matched Mixtures name: … R-LATE % 15 + % 5 DERİ SPREYİ, ÇÖZELTİ, 50 ML ... R-LATE % 15 + % 5 DERİ SPREYİ, ÇÖZELTİ, 6.5 ML ... Prilocaine HCl 4% Epineph 1:200000inj …
Matched Products: … 4% Citanest Plain Dental ... PRICANEST® 4% CARPULES POR 1.8 ML ... PRESTIGE® PRILOCAINA CLORHIDRATO AL 4% …
Ketotifen is a benzocycloheptathiophene derivative with potent antihistaminic and mast cell stabilizing properties. It has a similar structure to some other first-generation antihistamines such as cyproheptadine and azatadine. Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis. In the...
Approved
Matched Iupac: … 2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.0^{3,7}]tetradeca-1(14),3(7),4,10,12-pentaen-8-one …
Matched Products: … KENALER® - R ... KETEN SYRUP 1 mg/5 ml ... ASMAFEN SYRUP 1 mg/5 ml …
Paritaprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Synonyms: … (2R,6S,12Z,13aR,14aR,16aS)-N-(cyclopropanesulfonyl)-6-[(5-methylpyrazine-2-carbonyl)amino]-5,16-dioxo ... -2-[(phenanthridin-6-yl)oxy]-1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydrocyclopropa[e]pyrrolo[ …
Matched Iupac: … -6-yloxy)-3,16-diazatricyclo[14.3.0.0^{4,6}]nonadec-7-ene-4-carboxamide ... (1S,4R,6S,7Z,14S,18R)-N-(cyclopropanesulfonyl)-14-(5-methylpyrazine-2-amido)-2,15-dioxo-18-(phenanthridin …
Matched Description: … first line therapy option when used in combination with other antivirals for genotypes 1a, 1b, and 4[ ... 2015, Technivie is indicated in combination with [DB00811] for the treatment of patients with genotype 4
Gelatin is a multifunctional ingredient that is used in foods, pharmaceuticals, cosmetics, and photographic films as a gelling agent, stabilizer, thickener, emulsifier, as well as film former. As a thermoreversible hydrocolloid with a small gap between its melting and gelling temperatures, gelatin provides unique advantages over carbohydrate-based gelling agents. Gelatin...
Approved
Vet approved
Withdrawn
Matched Mixtures name: … GELOFUSINE® ISO 4% …
Matched Products: … GELAFUNDIN 4 ... INFUSOL SG (SUCCINYLATED GELATIN (Bovine) INTRAVENOUS INFUSION 4% w/v) …
Aluminum oxide has a chemical formula Al2O3. It is amphoteric in nature, and is used in various chemical, industrial and commercial applications. It is considered an indirect additive used in food contact substances by the FDA.
Approved
Matched Products: … ALUTACID ANTACID MIXTURE 4% w/w ... ALUMINIUM HYDROXIDE MIXTURE BP 4% w/w …
Displaying drugs 201 - 225 of 10999 in total