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Displaying drugs 201 - 225 of 9612 in total

Galcanezumab

Galcanezumab is a humanized monoclonal antibody developed by Eli Lilly and Company against human calcitonin gene-related peptide (CGRP). Although several small-molecule CGRP receptor antagonists have been developed, humanized monoclonal antibodies like galcanezumab are specifically designed to selectively bind to CGRP entities with high potency. Given this target specificity, lack of...
Approved
Investigational
Matched Description: … migraine and the treatment of episodic cluster headache. ... Galcanezumab was approved by the FDA in September 2018, and is indicated for the preventive treatment of ... [A33112] Given this target specificity, lack of off-target toxicity, and characteristic proteolysis profile …

Carglumic acid

Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl glutamate synthase. This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and cause neurologic problems, cerebral edema, coma, and death. Carglumic acid was...
Approved
Matched Description: … Food and Drug Administration (FDA) on 18 March 2010. ... Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl ... This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the …

Acetohexamide

A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. Acetohexamide has been discontinued in the US market.
Approved
Investigational
Withdrawn
Matched Categories: … combinations of sulfonamides …

Sulfamethazine

A sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides.
Approved
Investigational
Vet approved
Matched Description: … It has a spectrum of antimicrobial action similar to other sulfonamides. …
Matched Categories: … combinations of sulfonamides …

Ioxaglic acid

Ioxaglic acid is marketed as Hexabrix. This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic imaging procedures. Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray film, improving the visualization of important structures and organs during...
Approved
Investigational
Matched Description: … ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray film, improving the visualization of …
Matched Categories: … Diagnostic Uses of Chemicals …

Metrizoic acid

Metrizoic acid is a molecule used as a contrast medium. It present a higher risk of allergic reactions due to its high osmolality. Its approval has been discontinued by the FDA. One study in 1976 demonstrated that metrizoic acid, when used for cardiac angiography, was well tolerated. A total of...
Approved
Matched Description: … Seven cases of ventricular fibrillation, and 5 of significant bradycardia/asystole, were associated with ... It present a higher risk of allergic reactions due to its high osmolality. ... With two exceptions, all complications occurred during injection of the right coronary artery. …
Matched Categories: … Diagnostic Uses of Chemicals …

Quinupramine

Quinupramine has been approved in France under the brand name Kinupril, as an antidepressant .
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Bevacizumab

There is a great deal of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and proliferation of cancer cells.[A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and tumor growth, which are all factors that contribute to its attractiveness as a therapeutic target for anti-cancer...
Approved
Investigational
Matched Description: … with severe cases of COVID-19. ... for the survival and proliferation of cancer cells. ... There is a great deal of evidence indicating that vascular endothelial growth factor (VEGF) is important …
Matched Products: … KRABEVA Bevacizumab (r-DNA Origin) Concentrate for Solution for Intravenous Infusion 25mg/mL …

Meclizine

Meclizine is a histamine H1 antagonist with antiemetic and antivertigo properties. It is used in the symptomatic treatment of motion sickness and control of vertigo associated with vestibular system diseases. It also exhibits anticholinergic, central nervous system depressant, and local anesthetic effects. Commonly marketed under the brand name Antivert in...
Approved
Matched Description: … It is used in the symptomatic treatment of motion sickness and control of vertigo associated with vestibular …
Matched Products: … VERTINON (R) 25 MG …

Formoterol

Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers....
Approved
Investigational
Matched Description: … its active (R;R)- and inactive (S;S)-enantiomers. ... of action (2-3 minutes), which is at least as fast as [salbutamol], combined with a long duration of ... Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was …
Matched Mixtures name: … TIOFORM DİSCAİR 18/12 MCG İNHALASYON İÇİN TOZ, 60 DOZ ... AERODAY 18/12 MCG INHALASYON IÇIN TOZ IÇEREN BLISTER, 60 DOZ ... FEROMIS 18/12 MCG İNHALASYON İÇİN TOZ İÇEREN KAPSÜL, 60 ADET …

Ezogabine

Ezogabine (D23129) is a close structural analog of the centrally acting analgesic flupitrine. It is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED) and is currently being studied in Phase 3 trials as an adjunctive treatment for partial-onset seizures in adult patients with refractory epilepsy....
Approved
Investigational
Matched Description: … FDA approved in June 10, 2011 under the name of ezogabine. ... Ezogabine (D23129) is a close structural analog of the centrally acting analgesic flupitrine. …

Iobenguane

Synthetic guanethidine derivative that locates phaeochromocytomas and neuroblastomas. The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline. Iodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture. Images are produced by a I123 MIBG scintigraphy. FDA approved...
Approved
Investigational
Matched Description: … The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that …
Matched Categories: … Diagnostic Uses of Chemicals …

Technetium Tc-99m mebrofenin

Technetium Tc 99m Mebrofenin is a diagnostic radiopharmaceutical composed of diisopropyl-iminodiacetic acid (DISIDA) attached to a technetium-99m ion. Following intravenous injection, single photon emission computer tomography (SPECT) imaging of the liver or gallbladder is performed using a gamma camera to detect the gamma rays emitted by the technetium-99m as it...
Approved
Matched Description: … Technetium Tc 99m Mebrofenin is a diagnostic radiopharmaceutical composed of diisopropyl-iminodiacetic ... Following intravenous injection, single photon emission computer tomography (SPECT) imaging of the liver ... More specifically, mebrofenin is taken up into hepatocytes through the action of OATP1B1 and OATP1B3 …
Matched Categories: … Diagnostic Uses of Chemicals …

Dibenzepin

Dibenzepin is approved for use in Europe.
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Gadobenic acid

Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based contrast agent (GBCA) used primarily for MR imaging of the liver. It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and R2 relaxivity....
Approved
Investigational
Matched Description: … gadobenate dimeglumine, is a linear MRI gadolinium-based contrast agent (GBCA) used primarily for MR imaging of …
Matched Categories: … Diagnostic Uses of Chemicals …

Ethylhexyl methoxycrylene

Ethylhexyl methoxycrylene is a photostabilizer that preserves the effectiveness of UV filters by interacting with both the singlet and triplet states . It returns UV filters to their ground states without absorbing sunlight . It is used as a solvent for crystalline UV filters and is easily emulsified and suitable...
Approved
Experimental
Matched Description: … Ethylhexyl methoxycrylene is a photostabilizer that preserves the effectiveness of UV filters by interacting …
Matched Mixtures name: … Almost Makeup SPF 18 …

Phenazopyridine

Phenazopyridine, also known as Pyridium, is a urinary tract analgesic used for the short-term management of urinary tract irritation and its associated unpleasant symptoms such as burning and pain during urination. In the USA, this drug was previously marked by Roche but has been discontinued by the FDA. It is...
Approved
Matched Description: … Ingestion of phenazopyridine is found to change the appearance of the urine by imparting an orange or ... [L7832] It is still used in various parts of the world. ... Phenazopyridine, also known as Pyridium, is a urinary tract analgesic used for the short-term management of …

Cocaine

An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of...
Approved
Illicit
Matched Description: … An alkaloid ester extracted from the leaves of plants including coca. ... its reinforcing effects is thought to involve inhibition of dopamine uptake. ... It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse …
Matched Categories: … Esters of Benzoic Acid ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Bezlotoxumab

Bezlotoxumab is a fully humanized ImmunoglobulinG1 (IgG1) kappa monoclonal antibody that binds to Clostridium difficile toxin B and neutralizes its effects. First approved by the FDA on October 21, 2016, bezlotoxumab is used to reduce the recurrence of C. difficile infection. On November 22, 2016, the Committee for Medicinal Products...
Approved
Investigational
Matched Description: … [A260106] The drug was granted full approval by the EMA on January 18, 2017.[L47191] ... Agency recommended the granting of a marketing authorization. ... First approved by the FDA on October 21, 2016,[A260106] bezlotoxumab is used to reduce the recurrence of …

Dyphylline

Dyphylline is a theophylline derivative with broncho- and vasodilator properties. It is typically used in the management of asthma, cardiac dyspnea, and bronchitis.
Approved
Matched Description: … It is typically used in the management of asthma, cardiac dyspnea, and bronchitis. …
Matched Categories: … combinations of xanthines …

Tolazamide

A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide.
Approved
Investigational
Matched Description: … A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide. …
Matched Categories: … combinations of sulfonamides …

Sulfathiazole

Sulfathiazole is a short-acting sulfa drug. It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide. Except for those formulated for vaginal use, the FDA withdrew its approval for the use of...
Approved
Vet approved
Withdrawn
Matched Description: … Except for those formulated for vaginal use, the FDA withdrew its approval for the use of all drug products …
Matched Categories: … combinations of sulfonamides …

Sulfameter

Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections.
Approved
Matched Categories: … combinations of sulfonamides …

Sodium phosphate, monobasic

Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.
Approved
Matched Categories: … Drugs for Treatment of Hypercalcemia …

Clomifene

A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
Approved
Investigational
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Displaying drugs 201 - 225 of 9612 in total