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Displaying drugs 2226 - 2250 of 15759 in total

Epinastine

Epinastine is used for the prevention of itching associated with allergic conjunctivitis. It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and H2-receptors to...
Approved
Investigational
Matched Description: … multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell ... -receptors to stop itching and provide lasting protection, and 3. prevents the release of proinflammatory ... degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and H2 …
Matched Categories: … Acid Reducers ... Decongestants and Antiallergics …

Senna leaf

Approved
Experimental
Matched Mixtures name: … SENNA LEAF and DOCUSATE SODIUM …

Sulfisoxazole

A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms.
Approved
Vet approved
Matched Description: … A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive …
Matched Categories: … Sulfonamides and trimethoprim ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Tioguanine

An antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
Approved
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Selenomethionine Se-75

Approved
Matched Iupac: … (2S)-2-amino-4-[methyl(⁷⁵Se)selanyl]butanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …

N-alkyl ethylbenzyl dimethyl ammonium (C12-C14)

N-alkyl ethylbenzyl dimethyl ammonium (c12-c14) is a quaternary ammonium compound with surfactant properties. It is found in sanitizing solutions or soaps as an active ingredient due to its antimicrobial properties. Employed in a great variety of cleaning agents and sanitizing agents, it possesses relatively broad gram-positive and gram-negative antibacterial activities...
Approved
Matched Description: … and gram-negative antibacterial activities and relatively little chance for systemic absorption and ... Employed in a great variety of cleaning agents and sanitizing agents, it possesses relatively broad gram-positive …
Matched Mixtures name: … Prevent X Hand Sanitizer and Antiseptic Skin Protectant …

Betazole

A histamine H2 agonist used clinically to test gastric secretory function.
Approved

Secretin human

Human secretin is a gastrointestinal peptide hormone that regulates secretions in the stomach, pancreas, and liver. The hormone is produced from the enterochromaffin cells in the duodenum in response to the duodenal content with the pH less than 4.5 . The main action of secretin is to stimulate the pancreas...
Approved
Matched Description: … The carboxyl-terminal amino acid, valine, is amidated. ... It contains an amino acid sequence identical to the naturally occurring hormone consisting of 27 amino ... of pancreatic exocrine dysfunction and the diagnosis of gastrinoma, and facilitate the identification …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Flumazenil

Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine receptor complex, thereby reversing the effects of benzodiazepine on the central nervous system.
Approved
Matched Iupac: … ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,11,13-pentaene- …
Matched Description: … Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that …

Uracil mustard

Nitrogen mustard derivative of uracil. It is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal and bone marrow damage.
Approved
Matched Description: … and bone marrow damage. ... It is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Pertussis vaccine

Pertussis vaccine is under investigation in clinical trial NCT01698346 (Pertussis (Tdap) Vaccination in Pregnancy).
Approved
Investigational
Matched Mixtures name: … Diphtheria and Tetanus Toxoids With Pertussis Vaccine Adsorbed …

Thiohexam

Thiohexam is a rubber cure accelerator. It is also a known allergen and dermatological sensitizer. Sensitivity to Thiohexam may be identified with a clinical patch test.
Approved
Experimental
Matched Description: … It is also a known allergen and dermatological sensitizer. …
Matched Categories: … Cell-mediated Immunity …

Taurolidine

Taurolidine is an antimicrobial used for the prevention of catheter-related infections. It is a derivative of the amino acid taurine. It was first synthesized in the 1970s and was originally used as a prophylactic against intraperitoneal bacterial infections in patients with peritonitis. In November 2023, a catheter lock solution of...
Approved
Investigational
Matched Iupac: … 4-[(1,1-dioxo-1lambda6,2,4-thiadiazinan-4-yl)methyl]-1lambda6,2,4-thiadiazinane-1,1-dione …
Matched Description: … It is a derivative of the amino acid [taurine]. ... It was first synthesized in the 1970s and was originally used as a prophylactic against intraperitoneal ... marketed as Defencath - received FDA approval under the Limited Population Pathway for Antibacterial and …
Matched Categories: … Blood Substitutes and Perfusion Solutions …

Insulin detemir

Insulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A2358, A2359, A2360, A44] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta...
Approved
Matched Description: … amino acid at position B29. ... [A2358, A2359, A2360, A44] This insulin analogue has a 14-C fatty acid, myristic acid, bound to the lysine ... tissues such as the liver, fat cells, and skeletal muscle. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Eltrombopag

Eltrombopag is used to treat low blood platelet counts in adults with chronic immune (idiopathic) thrombocytopenia (ITP), when certain other medicines, or surgery to remove the spleen, have not worked well enough. ITP is a condition that may cause unusual bruising or bleeding due to an abnormally low number of...
Approved
Matched Iupac: … hydroxy-[1,1'-biphenyl]-3-carboxylic acid ... 3'-{2-[(4Z)-1-(3,4-dimethylphenyl)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-ylidene]hydrazin-1-yl}-2'- …
Matched Description: … thrombocytopenia (low blood platelet counts) in patients with chronic hepatitis C to allow them to initiate and …
Matched Categories: … Blood and Blood Forming Organs …

Midostaurin

Midostaurin (as Rydapt) is a multitarget kinase inhibitor for the treatment for adult patients with newly diagnosed acute myeloid leukemia (AML) who have a specific genetic mutation called FLT3. It was initially characterized as a potential broad-spectrum antineoplastic agent, with activity toward diverse solid and hematopoietic tumors . It was...
Approved
Investigational
Matched Iupac: … N-[(2S,3R,4R,6R)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{ …
Matched Description: … characterized as a potential broad-spectrum antineoplastic agent, with activity toward diverse solid and ... It was approved on April 28, 2017 and has shown to increase the overall survival rate in patients with …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Clofedanol

Clofedanol is a centrally-acting cough suppressant available in Canada under the trade name Ulone. It is not available in the United States.
Approved
Withdrawn
Matched Mixtures name: … Chlophedianol Hydrochloride, Dexchlorpheniramine Maleate, and Pseudoephedrine Hydrochloride …
Matched Categories: … Cough and Cold Preparations …

Morpholinylmercaptobenzothiazole

Approved
Experimental
Matched Categories: … Cell-mediated Immunity …

Cladribine

Cladribine is a purine analogue or a chlorinated derivative of adenine that causes apoptosis of B and T lymphocytes. Cladribine was first approved in the United States in 1993 initially as a treatment for a number of hematological malignancies; currently, it is approved for the treatment of hairy cell leukemia....
Approved
Investigational
Matched Description: … treatment for a number of hematological malignancies; currently, it is approved for the treatment of hairy cell ... Cladribine is a purine analogue or a chlorinated derivative of adenine [A263733] that causes apoptosis of B and ... [A263733] In 2017 in Europe and in 2019 in the United States, cladribine was also approved for the treatment …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …

Luteinizing hormone

Approved
Matched Mixtures name: … MENOGON 75 IU Powder and Solvent for solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Mipomersen

Mipomersen sodium, which was known as the investigational drug, isis-301012, is the salt form of a synthetic phosphorothioate oligonucleotide. Mipomersen sodium prevents the formation of apo B-100, resulting in a decrease in the levels of apolipoprotein B (apo B), low density lipoprotein (LDL), and total cholesterol. Mipomersen is indicated in...
Approved
Investigational
Matched Description: … , resulting in a decrease in the levels of apolipoprotein B (apo B), low density lipoprotein (LDL), and ... It is marketed under the brand name Kynamro in the United States, and the FDA label includes a black ... Specifically, elevations in the liver enzymes, i.e. transaminases, and in liver fat (hepatic steatosis …
Matched Categories: … Nucleic Acid Probes ... Nucleic Acids, Nucleotides, and Nucleosides …

Inclisiran

Inclisiran is a long-acting, synthetic small interfering RNA (siRNA) directed against proprotein convertase subtilisin-kexin type 9 (PCSK9), which is a serine protease that regulates plasma low-density lipoprotein cholesterol (LDL-C) levels. By binding to PCSK9 messenger RNA, inclisiran prevents protein translation of PCSK9, leading to decreased concentrations of PCSK9 and plasma...
Approved
Investigational
Matched Description: … RNA, inclisiran prevents protein translation of PCSK9, leading to decreased concentrations of PCSK9 and ... 11, 2020, the European Commission (EC) granted authorization for marketing inclisiran as the first and ... plasma LDL-C levels offers an additional benefit of reducing the risk of cardiovascular disease (CVD) and …
Matched Categories: … Nucleic Acid Probes ... Nucleic Acids, Nucleotides, and Nucleosides …

Erdosteine

Erdosteine is a drug that causes a breakdown of mucus, also known as a mucolytic agent. It is a thiol derivative produced for the clinical management of chronic obstructive bronchitis, in addition to infective exacerbations of chronic bronchitis. This drug contains sulfhydryl groups which are released after erdosteine undergoes hepatic...
Approved
Investigational
Matched Iupac: … 2-({[(2-oxothiolan-3-yl)carbamoyl]methyl}sulfanyl)acetic acid …
Matched Description: … and more effectively than placebo and reduced the adhesivity of sputum more effectively than ambroxol ... Erdosteine 300mg twice daily reduced cough (both frequency and severity) and sputum viscosity more quickly ... Erdosteine has been shown to be safe and well tolerated in clinical trials. …
Matched Categories: … Cough and Cold Preparations …

Pancrelipase

Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands. The pancrelipase mixture was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved on April 12, 2010. For further information on the components of this mixture...
Approved
Investigational
Matched Description: … Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and ... [L2510] For further information on the components of this mixture please visit [DB11065], [DB11066] and ... [L2509] The pancrelipase mixture was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved …
Matched Mixtures name: … Pancreatin and Enzyme Formula - Tablet …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …

2,2'-Dibenzothiazyl disulfide

2,2'-Dibenzothiazyl disulfide is an accelerator used in the processing process for natural and synthetic rubber and plastic regeneration. It is also a known allergen and dermatological sensitizer. Sensitivity to 2,2'-Dibenzothiazyl disulfide may be identified with a clinical patch test.
Approved
Experimental
Matched Description: … rubber and plastic regeneration. ... It is also a known allergen and dermatological sensitizer. ... 2,2'-Dibenzothiazyl disulfide is an accelerator used in the processing process for natural and synthetic …
Matched Categories: … Cell-mediated Immunity …
Displaying drugs 2226 - 2250 of 15759 in total