Displaying drugs 2351 - 2375 of 14977 in total
Vespula pensylvanica venom protein
Vespula pensylvanica venom protein is an extract of Vespula pensylvanica venom. Vespula pensylvanica venom protein is used in allergenic testing.
Approved
Matched Categories: … Bee and Wasp Venom …
Muromonab
Murine monoclonal antibody specific to CD3 T-cell lymphocyte antigens. More specifically it is a purified murine (mouse) monoclonal antibody, directed against the CD3 (T3) receptor on the surface of human T-cells (T-lymphocytes) cultured using the murine ascites method. Muromonab is 93% monomeric immune globulin G type 2a (IgG2a).
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Dupilumab
Dupilumab is a fully human monoclonal antibody of the immunoglobulin G4 subclass that binds to the interleukin-4 (IL-4) receptor, inhibiting the receptor signaling pathways. As an interleukin-4 receptor alpha antagonist, dupilumab inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and immunological reactions in several atopic or...
Approved
Investigational
Matched Description: … immunological reactions in several atopic or allergic conditions, such as eczema, allergic reaction, and ... dermatitis, asthma as an add-on maintenance treatment, chronic rhinosinusitis with nasal polyposis, and ... inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents …
Mecamylamine
A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
Approved
Investigational
Matched Description: … A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain …
Matched Categories: … Secondary and Tertiary Amines …
Matched Categories: … Secondary and Tertiary Amines …
Dantron
Withdrawn from the Canadian, US, and UK markets in 1998 due to genotoxicity.
Approved
Investigational
Withdrawn
Matched Description: … Withdrawn from the Canadian, US, and UK markets in 1998 due to genotoxicity. …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Categories: … Alimentary Tract and Metabolism …
Fluprednisolone
A synthetic glucocorticoid with anti-inflammatory properties.
Approved
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Terpin hydrate
Terpin hydrate is an expectorant, commonly used to loosen mucus and ease congestion in patients presenting with acute or chronic bronchitis, and related pulmonary conditions. It is derived from sources such as turpentine, oregano, thyme and eucalyptus. It was popular in the United States since the late nineteenth century, but...
Approved
Experimental
Matched Description: … with acute or chronic bronchitis, and related pulmonary conditions. ... It is derived from sources such as turpentine, oregano, thyme and eucalyptus. ... Terpin hydrate is an expectorant, commonly used to loosen mucus and ease congestion in patients presenting …
Eleuthero
Eleuthero is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Categories: … Herbs and Natural Products …
Volanesorsen
Volanesorsen is an antisense oligonucleotide that binds to apoC-III mRNA to prevent its translation. It is indicated to treat familial chylomicronemia, a genetic condition that prevents breakdown of triglycerides and chylomicrons. This drug is not commonly prescribed as it is used as an adjunct to diet in patients at high...
Approved
Investigational
Matched Description: … indicated to treat familial chylomicronemia, a genetic condition that prevents breakdown of triglycerides and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Pembrolizumab
Pembrolizumab is a highly selective IgG4-kappa humanized monoclonal antibody against PD-1 receptors. It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotype containing a stabilizing S228P Fc mutation. It contains 32 cysteine residues and the complete folded molecule includes...
Approved
Matched Description: … as interchain bonds and 23 interchain bonds. ... [A18829] It contains 32 cysteine residues and the complete folded molecule includes 4 disulfide linkages ... [F136] It was developed by Merck & Co and first approved for the treatment of metastatic malignant melanoma …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Alemtuzumab
Alemtuzumab is a humanized monoclonal antibody specific to lymphocyte antigens. It is a recombinant DNA-derived humanized monoclonal antibody (Campath-1H) that is directed against the 21-28 kD cell surface glycoprotein, CD52. The Campath-1H antibody is an IgG1 kappa with the human variable framework and constant regions, and complementarity-determining regions from a...
Approved
Investigational
Matched Description: … The Campath-1H antibody is an IgG1 kappa with the human variable framework and constant regions, and ... [L43397] It is marketed as LEMTRADA for multiple sclerosis (MS) treatment and CAMPTAH for B-cell chronic ... The dose of alemtuzumab used for B-CLL is much higher than that for MS, and also at more frequent dosing …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Oxprenolol
A beta-adrenergic antagonist used in the treatment of hypertension, angina pectoris, arrhythmias, and anxiety.
Approved
Matched Description: … A beta-adrenergic antagonist used in the treatment of hypertension, angina pectoris, arrhythmias, and …
Matched Categories: … oxprenolol and thiazides ... Beta Blocking Agents and Thiazides ... oxprenolol and other diuretics ... Beta Blocking Agents, Non-Selective, and Thiazides …
Matched Categories: … oxprenolol and thiazides ... Beta Blocking Agents and Thiazides ... oxprenolol and other diuretics ... Beta Blocking Agents, Non-Selective, and Thiazides …
Isoxaflutole
Balance has been investigated for the treatment of Chronic Renal Failure and Peritoneal Membrane Disorder.
Approved
Experimental
Investigational
Matched Description: … Balance has been investigated for the treatment of Chronic Renal Failure and Peritoneal Membrane Disorder …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Dotatate gallium Ga-68
Dotatate gallium (Ga-68) is a somatostatin-2 receptor analog which is radiolabeled with gallium 68 as a positron-emitting radioisotope. Ga-68 dotatate has a high affinity for somatostatin-2 receptor and it is rapidly excreted from the nontarget sites which gives it an ideal candidate for imaging neuroendocrine tumors. Dotatate gallium (Ga-68) explotes...
Approved
Investigational
Matched Description: … Ga-68 dotatate has a high affinity for somatostatin-2 receptor and it is rapidly excreted from the nontarget ... [A31358] Dotatate gallium 68 was developed by Advanced Accelerator Applications USA, Inc. and FDA approved ... Dotatate gallium (Ga-68) explotes its ability to detect somatostatin receptor scintigraphy and this characteristic …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Eslicarbazepine
Eslicarbazepine is an anti-epileptic medication available commercially as eslicarbazepine acetate.
Approved
Matched Categories: … Eslicarbazepine and prodrugs …
Trastuzumab deruxtecan
Trastuzumab deruxtecan is a HER2-directed antibody attached to a topoisomerase inhibitor that is approved for use in certain types of treatment-resistant HER2-positive cancers. It is classified as an antibody-drug conjugate. The cleavable peptide linker used to bind the antibody and drug in this product distinguishes it from other members of...
Approved
Investigational
Matched Description: … The cleavable peptide linker used to bind the antibody and drug in this product distinguishes it from ... A188988]
Trastuzumab deruxtecan was developed by Daiichi Sankyo in collaboration with AstraZeneca and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Ardeparin
Ardeparin, marketed under the US trade name Normiflo, is a low molecular weight heparin (LMWH) anticoagulant used for the prevention of postoperative venous thrombosis. Ardeparin is derived via peroxide degradation of heparin extracted from porcine intestinal mucosa. Its molecular weight ranges from 2000 to 15,000 with an average molecular weight...
Approved
Investigational
Withdrawn
Matched Categories: … Heparin and similars …
Pentamidine
Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
Approved
Investigational
Matched Description: … It may cause diabetes mellitus, central nervous system damage, and other toxic effects. ... Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in …
Matched Categories: … Agents Against Leishmaniasis and Trypanosomiasis ... Antiparasitic Products, Insecticides and Repellents …
Matched Categories: … Agents Against Leishmaniasis and Trypanosomiasis ... Antiparasitic Products, Insecticides and Repellents …
Pipradrol
Pipradrol (Meratran) was initially developed in the 1950s as an antidepressant, however, the adverse effects associated with its use and its abuse potential led to its withdrawal and international regulation . Pipradrol was made illegal in many countries in 1970s because of its potential for abuse. It is currently classified...
Approved
Matched Description: … acute toxicity and has been linked to three fatalities. ... its abuse potential led to its withdrawal and international regulation [L2524]. ... Experimentation with the drug and its derivatives for recreational purposes has led to many cases of …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Copper oxodotreotide Cu-64
Copper Cu 64 dotatate is a newly approved Cu labeled somatostatin analog and has several advantages over 68Ga-labeled somatostatin analogs for positron emission tomography (PET). Copper Cu 64 dotatate has a longer half-life and can be produced once a day as opposed to several times a day, and lower positron...
Approved
Matched Description: … times a day, and lower positron energy lending to improved spatial resolution. ... Copper Cu 64 dotatate is a newly approved Cu labeled somatostatin analog and has several advantages over ... [A220348] Copper Cu 64 dotatate has a longer half-life and can be produced once a day as opposed to several …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Efanesoctocog alfa
Efanesoctocog alfa (BIVV001) is a recombinant factor VIII (FVIII) analogue fusion protein used for the routine prophylaxis, perioperative management of bleeding and on-demand treatment and control of bleeding episodes in patients with hemophilia A. The use of FVIII replacement products is beneficial in patients with hemophilia A; however, their quality...
Approved
Investigational
Matched Description: … on-demand treatment and control of bleeding episodes in patients with hemophilia A. ... FVIII) analogue fusion protein used for the routine prophylaxis, perioperative management of bleeding and ... [A257464] Efanesoctocog alfa was designed to have an extended half-life, and to surpass the half-life …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Diethylpropion
A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)
Approved
Illicit
Matched Categories: … Alimentary Tract and Metabolism …
Displaying drugs 2351 - 2375 of 14977 in total