Advanced Filter

Filter by Group

Filter by Market Availability

Displaying drugs 1 - 25 of 14894 in total
Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an allogeneic cellularized scaffold product used for the treatment of adults with thermal burns containing intact dermal elements for which surgical intervention is clinically indicated (also known as deep partial-thickness burns). It was developed as an alternative to autografting...
Approved
Matched Synonyms: … allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat ... Viable and metabolically active allogeneic human NIKS keratinocytes and human dermal fibroblasts cellularized …
Matched Name: … Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen
Matched Description: … Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an ... , which are grown together on a murine collagen matrix to make a bi-layered construct (i.e. a cellularized ... active and viable cells, provide a variety of human growth factors and cytokines as well as extracellular …
Pork Collagen is used within MACI® (autologous cultured chondrocytes on porcine collagen membrane) as an autologous cellularized scaffold product indicated for the repair of single or multiple symptomatic, full-thickness cartilage defects of the knee with or without bone involvement in adults. It serves as an alternative repair treatment for patients...
Approved
Investigational
Matched Synonyms: … Collagen Porcine ... Collagen, Porcine …
Matched Name: … Pork collagen
Matched Description: … Pork Collagen is used within MACI® (autologous cultured chondrocytes on porcine collagen membrane) as ... It has been used since 1995 as Carticel and gained biologic license in 1997. ... an autologous cellularized scaffold product indicated for the repair of single or multiple symptomatic …
Matched Mixtures name: … Le-Blen Nano Collagen Peptide Serum …
Azficel-T is an autologous cellular product composed of fibroblasts indicated for improvement of the appearance of moderate to severe nasolabial fold wrinkles in adults. Dermal fibroblasts are collected from the post-auricular biopsy tissue and aseptically expanded using standard tissue-culture procedures until sufficient cells for three doses are obtained [FDA Label]....
Approved
Investigational
Matched Synonyms: … Autologous cultured fibroblasts …
Matched Description: … Dermal fibroblasts are collected from the post-auricular biopsy tissue and aseptically expanded using ... fibroblasts has shown to improve wrinkle and acne scar appearance than with placebo treatment [A31920 ... Azficel-T is an autologous cellular product composed of fibroblasts indicated for improvement of the …
Matched Categories: … Autologous Cultured Cell …
Approved
Matched Name: … Smallpox and Monkeypox Vaccine, Live, Non-replicating …
Holoclar (ex vivo expanded autologous human corneal epithelial cells containing stem cells) is a stem cell therapy used to treat limbal stem cell deficiencies.
Approved
Investigational
Matched Name: … Ex vivo expanded autologous human corneal epithelial cells containing stem cells …
Matched Description: … Holoclar (_ex vivo_ expanded autologous human corneal epithelial cells containing stem cells) is a stem …
Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine is used to prevent invasive meningococcal disease, which is caused by bacteria Neisseria meningitidis entering the bloodstream and invading the blood-brain barrier to cause a variety of infections such as septicemia, meningitis, and pneumonia. Several serogroups of N....
Approved
Matched Name: … Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine …
Matched Description: … Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine is used ... meningococcal disease, which is caused by bacteria _Neisseria meningitidis_ entering the bloodstream and ... invading the blood-brain barrier to cause a variety of infections such as septicemia, meningitis, and
Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. Libmeldy was granted orphan designation by the EMA in April 2007, and was...
Approved
Matched Synonyms: … Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC ... Autologous CD34+ cells transduced with lentiviral vector which encodes for the aryl Sulfatase A complimentary …
Matched Description: … Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous ... CD34+ enriched hematopoietic stem and progenitor cells transduced _ex vivo_ using a lentiviral vector ... [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing …
Matched Categories: … Autologous Cultured Cell ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Autologous Hematopoietic Stem Cell-Based Gene Therapy …
Lifileucel is a tumour-derived autologous T cell immunotherapy composed of a suspension of tumour-derived T cells from the patient which undergo isolation, ex vivo expansion, and activation Lifileucel was granted accelerated approval by the FDA on February 16, 2024, for the treatment of unresectable or metastatic melanoma.
Approved
Investigational
Matched Synonyms: … Autologous tumor infiltrating lymphocytes ... Tumor infiltrating lymphocytes, autologous
Matched Description: … Lifileucel is a tumour-derived autologous T cell immunotherapy composed of a suspension of tumour-derived ... T cells from the patient [L50171] which undergo isolation, ex vivo expansion, and activation[A263341 …
Matched Categories: … Autologous Cellular Immunotherapy ... Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents …
The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. [PubChem]
Approved
Investigational
Matched Synonyms: … para-aminohippurate ... para-aminohippuric acid ... N-(para-aminobenzoyl)glycine …
Matched Description: … Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory …
Matched Categories: … para-Aminobenzoates ... Indicators and Reagents ... Benzamides and benzamide derivatives ... Tests for Renal Function and Ureteral Injuries …
Betibeglogene autotemcel is an autologous gene therapy that adds functional copies of the β-globin gene (βA-T87Q-globin) to hematopoietic stem cells in order to treat β-thalassemia. β-thalassemia is a condition caused by mutations in the β-globin gene (HBB) that leads to a significant decrease in the production of β-globin. This affects...
Approved
Investigational
Matched Synonyms: … Autologous CD34+ cells encoding βA-T87Q-Globin gene …
Matched Description: … Betibeglogene autotemcel is an autologous gene therapy that adds functional copies of the β-globin gene ... transfusions are required for survival and the prevention of serious complications. ... This affects hemoglobin levels, and in patients with severe forms of this disease, long-term red cell …
Matched Categories: … Autologous Cultured Cell ... Blood and Blood Forming Organs ... Autologous Hematopoietic Stem Cell-Based Gene Therapy …
Omidubicel is a nicotinamide-modified allogeneic hematopoietic progenitor cell therapy derived from cord blood used as an allogeneic stem cell donor source. Umbilical blood cord cells are expanded ex-vivo and nicotinamide (a form of vitamin B3) is used as an active agent in the culture system to inhibit the differentiation and...
Approved
Investigational
Matched Synonyms: … Allogeneic, ex-vivo expanded, umbilical cord blood-derived hematopoietic CD34+ progenitor cells - cultured
Matched Description: … of hematopoietic stem and progenitor cells. ... Umbilical blood cord cells are expanded _ex-vivo_ and [nicotinamide] (a form of vitamin B3) is used as ... an active agent in the culture system to inhibit the differentiation and increase the functionality …
Matched Categories: … Cells, Cultured, Allogeneic …
Vayarin is a prescription medical food for the clinical dietary management of certain lipid imbalances blamed to be associated with attention deficit hyperactivity disorder (ADHD) in children. Vayarin contains Lipirinen, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and docosahexaenoic acid (DHA) [L1500, L1510]. Vayarin is currently available only...
Approved
Investigational
Matched Synonyms: … Phosphatidylserine, DHA, and EPA …
Matched Description: … Lipirinen_, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and ... Cost of the drug and patient aversion to the taste of Vayarin were significant reasons for therapy failure ... Vayarin is a specially formulated and designed to address the distinct, previously determined lipid nutritional …
Multiple myeloma is a malignancy involving the plasma cells of the bone marrow. It is a rare malignancy, with an estimated yearly incidence of 6.5 people per 100,000, and is variable in its presentation - some patients may remain entirely asymptomatic, while others may experience a range of symptoms including...
Approved
Investigational
Matched Synonyms: … Autologous bi-epitope BCMA-targeted CAR T-cells …
Matched Description: … Ciltacabtagene autoleucel (Carvykti, Jannsen Biotech Inc.) is a BCMA-directed genetically modified autologous ... It is a rare malignancy, with an estimated yearly incidence of 6.5 people per 100,000,[L40749] and is ... [A245854] While normally expressed on plasma blasts and plasma cells, BCMA is widely expressed on malignant …
Matched Categories: … Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents …
A member of the vitamin B complex. It used to be common in sunscreening agents until found to also be a sensitizer. The potassium salt is used therapeutically in fibrotic skin disorders.
Approved
Experimental
Matched Synonyms: … para-Aminobenzoic acid …
Matched Categories: … para-Aminobenzoates ... Emollients and Protectives …
Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations.[A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments.[L7799,L7802] Tamoxifen may no longer be the preferred treatment for these types of cancers...
Approved
Matched Synonyms: … (Z)-2-(para-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine ... 1-para-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene …
Matched Description: … treatment for these types of cancers as patients generally have better survival, side effect profiles, and
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Sulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline.
Approved
Matched Synonyms: … para-aminobenzenesulfonamide …
Matched Categories: … Sulfonamides and trimethoprim ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Brazil nut allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Castanha do para whole …
Sarocladium strictum allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, acremonium strictum ... Molds, rusts and smuts, cephalosporium acremonium …
Matched Products: … Molds, Rusts and Smuts, Cephalosporium acremonium …
Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain. Talquetamab binds to GPRC5D, a cell surface...
Approved
Investigational
Matched Synonyms: … -KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ... ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY, BISPECIFIC ... ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY; BISPECIFIC …
Matched Description: … arm comprising a heavy and light chain. ... It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each ... Talquetamab binds to GPRC5D, a cell surface receptor expressed predominantly on multiple myeloma cells, and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Monoclonal antibodies and antibody drug conjugates …
Anisindione is a synthetic anticoagulant and an indanedione derivative. Its anticoagulant action is mediated through the inhibition of the vitamin K-mediated gamma-carboxylation of precursor proteins that are critical in forming the formation of active procoagulation factors II, VII, IX, and X, as well as the anticoagulant proteins C and S,...
Approved
Matched Synonyms: … 2-para-Anisyl-1,3-indandione …
Matched Description: … Anisindione is a synthetic anticoagulant and an indanedione derivative. ... X, as well as the anticoagulant proteins C and S, in the liver. ... precursor proteins that are critical in forming the formation of active procoagulation factors II, VII, IX, and
Pyrethrum is the crude extract form obtained from flowers of the plant Chrysanthemum cinerariifolium. Pyrethrin refers to a more refined extract of pyrethrum. While pyrethrum extract is composed of 6 esters, both organic compounds mediate insecticidal activities. Pyrethrum-containing mixtures are used as a common insecticide to control specific pest species....
Approved
Matched Synonyms: … Pyrethrins and pyrethroids …
Matched Description: … Pyrethrum extract is also used used to treat head, body, and pubic lice infections. ... The active compound is absorbed by the lice and destroys them by acting on their nervous systems but …
Matched Mixtures name: … Medi and Lice Lice Killing ... Lice-Nil Lice and Eggs Killer ... Weeks and Leo Complete Lice Treatment …
The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though it is rarely used in this indication, having largely been replaced by dipyridamole and [regadenson].[A229833,A229838] Adenosine...
Approved
Investigational
Matched Description: … L31983] though it is rarely used in this indication, having largely been replaced by [dipyridamole] and
Matched Mixtures name: … Jayjun Collagen Skin Fit Mask Step 02 Collagen Skin Fit Mask ... Xycos Pink Collagen ... MULBIT Collagen Mask Pack …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … misoli Power Snail and Collagen Hydrog el Mask Pack ... rootree Treetherapy Rejuvenating Eye and Neck Treatment ... Collagen Cream …
Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting factors found in functioning human plasma. Also known as prothrombin complex concentrate, products containing this complex often include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and low levels of...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX, II, VII and X in combination …
Matched Description: … Coagulation factors are purified from pooled human plasma and subsequently sterilized and treated. ... For example, Kcentra (FDA) also contains the antithrombotic proteins C and S, while Bebulin VH (FDA) ... include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal injuries and corneal trauma. It has been approved by FDA for use in externally applied drugs...
Approved
Matched Synonyms: … D and C Yellow No. 7 …
Matched Description: … and corneal trauma. ... It has been approved by FDA for use in externally applied drugs and cosmetics. ... A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline …
Matched Mixtures name: … Minims Lidocaine and Fluorescein ... Fluorescein Sodium and Proparacaine Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride …
Matched Categories: … Indicators and Reagents …
Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any...
Approved
Investigational
Matched Description: … [A31504] It was developped by Novo Nordisk and FDA approved in October 16, 2013.[L1104] ... rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and ... secretion, some rFVIII molecules are cleaved at the C-terminal of the heavy chain (HC) at amino acid 720, and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … NOVOEIGHT® 2000 UI POLVO Y SOLVENTE PARA SOLUCIÓN PARA INYECCIÓN ... NOVOEIGHT® 3000 UI POLVO Y SOLVENTE PARA SOLUCIÓN PARA INYECCIÓN ... NovoEight 500IU Powder and Solvent for Solution for Injection …
Displaying drugs 1 - 25 of 14894 in total