Tubulin beta chain

BE0000143ProteinHumansTUBB

Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. It is acted on by 22 drugs in DrugBank.

Gene name
TUBB
UniProtKB entry
P07437Swiss-Prot
Cellular location
Cytoplasm, cytoskeleton
Residues / weight
444 residues · 49,671 Da
Also known as
TUBB5 · Tubulin beta-5 chain

Resolves to

Protein
UniProtP07437UniProt nameTBB5_HUMAN
Gene
HGNCHGNC:20778NCBI Gene203068GenBank338695GeneCardsTUBB
Pharmacology
IUPHAR/GtoPdb2640KEGGhsa:203068
Structure
PDB3QNZPDB3QO0PDB5N5N
Drugs

What you can answer from here — as of September 07, 2019

22DrugsApproved to experimental, with action, bond type and pharmacological action
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17GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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60+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Tubulin beta chain, how selective are they, and which programs against it are still in active trials?

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