Serotransferrin

BE0000510ProteinHumansTF

Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is acted on by 43 drugs in DrugBank.

Gene name
TF
UniProtKB entry
P02787Swiss-Prot
Cellular location
Secreted
Residues / weight
698 residues · 77,063 Da
Also known as
Beta-1 metal-binding globulin · Siderophilin · Transferrin

Resolves to

Protein
UniProtP02787UniProt nameTRFE_HUMAN
Gene
HGNCHGNC:11740NCBI Gene7018GenBank339453GeneCardsTF
Pharmacology
KEGGhsa:7018
Structure
PDB1A8EPDB1A8FPDB1B3E
Drugs

What you can answer from here — as of September 07, 2019

43DrugsApproved to experimental, with action, bond type and pharmacological action
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7Clinical trialsTrials of drugs acting on it, by phase and status
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22GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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134+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Serotransferrin, how selective are they, and which programs against it are still in active trials?

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