Lactones

DBCAT000498Pharmacologic class

Cyclic esters of hydroxy carboxylic acids, containing a 1-oxacycloalkan-2-one structure. Large cyclic lactones of over a dozen atoms are MACROLIDES. A DrugBank category of 107 drugs. 29 of them are approved.

Drugs: 6-Deoxyerythronolide B
Amphotericin B
Anetumab ravtansine
Aplyronine A
AVE9633
Azithromycin
Bafilomycin A1
Bafilomycin B1
Bivatuzumab mertansine
Brefeldin A
Bryostatin 1
Calcimycin
Candicidin
Cantuzumab mertansine
Carbomycin
Carrimycin
Cethromycin
Clarithromycin
Coltuximab ravtansine
Concanamycin A
Dehydroascorbic acid
Dicirenone
Dirithromycin
Doramectin
Eplerenone
and 82 more with a free account

What you can answer from here — as of August 24, 2016

107DrugsEach linked to its full drug card

107Drug targetsEvery drug–target pair in the class, with bond type

7,301Marketed productsAcross the regions we cover, with dosage forms and routes

14Routes of administrationHow the drugs in this class are given

Which targets do Lactones share, and which companies have late-stage candidates in this class?

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