Adrenergic alpha-1 Receptor Agonists
- Adrenergic alpha-1 Receptor Agonists
- Accession Number
- DBCAT000538 (DBCAT003342)
Compounds that bind to and activate ADRENERGIC ALPHA-1 RECEPTORS.
Drug Drug Description Midodrine An alpha-adrenergic agonist used to treat orthostatic hypotension. Phenylephrine An alpha-1 adrenergic agonist used in the management of hypotension, generally in the surgical setting associated with the use of anesthetics. Metaraminol For the treatment and prevention of hypotension due to hemorrhage, spinal anesthesia, and shock associated with brain damage Methoxamine An alpha adrenergic agonist used to treat hypotension. Mephentermine A sympathomimetic agent used in the treatment of hypotension. Cirazoline Cirazoline acts on a number of α adrenergic receptors. It is an agonist of α1A, partial agonist of α1B and α1D, and a nonselective antagonist of α2. It is believed... Epinephrine A hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma. Pseudoephedrine An alpha and beta adrenergic agonist used to treat nasal and sinus congestion, as well as allergic rhinitis. Oxymetazoline An alpha-1A adrenoceptor agonist used to treat nasal congestion, allergic reactions of the eye, and facial erythema associated with rosacea. Benzphetamine A sympathomimetic used to manage exogenous obesity short term. 4-Methoxyamphetamine Not Available Phendimetrazine A sympathomimetic amine used as adjunct therapy for the short term management of exogenous obesity. Norepinephrine A sympathomimetic used in the control of blood pressure during various hypotensive states and as an adjunct treatment during cardiac arrest. Droxidopa A medication used to treat symptomatic neurogenic orthostatic hypotension (nOH) caused by dopamine beta-hydroxylase deficiency, non-diabetic autonomic neuropathy and primary autonomic failure caused by conditions such as Parkinson's disease. Xylometazoline A direct-acting alpha-adrenergic agonist used for the symptomatic treatment of nasal congestion and minor inflammation due to allergies or colds. Pergolide A long-acting dopamine agonist that is uncommonly used for the management of Parkinson's disease, due to the risk for cardiac valvulopathy. Bromocriptine A dopamine D2 receptor agonist used for the treatment of galactorrhea due to hyperprolactinemia and other prolactin-related conditions, as well as in early Parkinsonian Syndrome. Apraclonidine An alpha adrenergic agonist used to treat raised intraocular pressure. Dipivefrin A prodrug of epinephrine used in ophthalmic solutions to reduce intraocular pressure in chronic open-angle glaucoma. Ergometrine An ergot alkaloid used for the treatment of postpartum haemorrhage and post abortion hemorrhage in patients with uterine atony. Naphazoline A sympathomimetic vasoconstrictor used for the symptomatic relief of redness and itching of the eye, and nasal congestion. Isometheptene A sympathomimetic used to relieve painful spasms in combination with other agents such as caffeine and metamizole. Clonidine An alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines. Tetryzoline An alpha-adrenergic agonist used in the temporary symptomatic relief of discomfort and redness of the eyes due to minor irritations, as well as alleviate nasal congestion. Racepinephrine A bronchodilator used to treat intermittent asthma. Dobutamine A beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery. 4-Bromo-2,5-dimethoxyphenethylamine Not Available
- Drugs & Drug Targets