Cytochrome P-450 CYP2E1 Inhibitors

Name
Cytochrome P-450 CYP2E1 Inhibitors
Accession Number
DBCAT002629
Description

Not Available

Drugs
DrugDrug Description
DisulfiramA carbamate derivative used to treat alcohol addiction.
MidostaurinAn antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL).
IsoniazidAn antibiotic used to treat mycobacterial infections; most commonly use in combination with other antimycobacterial agents for the treatment of active or latent tuberculosis.
ClotrimazoleA topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.
RheinNo approved indication.
ZucapsaicinA topical analgesic used as an adjunct to relieve severe pain of osteoarthritis of the knee in selected adult patients.
NabiloneA synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy.
TiclopidineA platelet aggregation inhibitor used in the prevention of conditions associated with thrombi, such as stroke and transient ischemic attacks (TIA).
NifedipineA dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension.
RufinamideAn antiepileptic drug used as adjunctive therapy to treat seizures associated with Lennox-Gastaut Syndrome (LGS).
EconazoleA topical antifungal used to treat tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis and tinea versicolor.
MiconazoleAn azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis.
NicotineA stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation.
ChlorzoxazoneA drug with muscle relaxant properties that is used as an adjunct to physical therapy and analgesics to treat stiffness and pain caused by a variety of musculoskeletal conditions.
FomepizoleAn inhibitor of alcohol dehydrogenase used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning.
AdemetionineS-Adenosylmethionine (SAMe) is used as a drug in Europe for the treatment of depression, liver disorders, fibromyalgia, and osteoarthritis. It has also been introduced into the United States market as...
PropofolA medication used in general anesthesia and for sedation.
AlosetronA 5-HT3 antagonist used to treat diarrhea-predominant IBS.
BifonazoleAn azole antifungal drug used to treat fungal skin infections, such as dermatomycosis.
BromazepamA short-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and severe anxiety.
ChlorpromazineA phenothiazine antipsychotic used to treat nausea, vomiting, preoperative anxiety, schizophrenia, bipolar disorder, and severe behavioral problems in children.
CimetidineA histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion.
DesipramineA tricyclic antidepressant used in the treatment of depression.
DiclofenacAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
EtoricoxibA selective COX-2 inhibitor used to relieve moderate post-surgical dental pain as a short-term treatment and inflammatory and painful symptoms of various forms of arthritis.
FluphenazineA phenothiazine used to treat patients requiring long-term neuroleptic therapy.
FlurazepamA long-acting benzodiazepine with a rapid onset of action that is commonly used to treat insomnia.
ImipramineA tricyclic antidepressant indicated for the treatment of depression and to reduce childhood enuresis.
Isosorbide dinitrateA vasodilator used to treat angina in coronary artery disease.
ItraconazoleAn antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis.
MetyraponeA steroid 11-beta-monooxygenase inhibitor used to test hypothalamic-pituitary ACTH function.
NicotinamideAn ingredient found in a variety of cosmetic products.
NortriptylineA tricyclic antidepressant used in the treatment of depression.
SildenafilA phosphodiesterase inhibitor used for the treatment of erectile dysfunction.
TegaserodA serotonin-4 (5-HT4) receptor agonist indicated for the treatment of constipation predominant irritable bowel syndrome (IBS-C) specifically in women under the age of 65. There is currently no safety or efficacy data for use of tegaserol in men.
MethimazoleA thionamide antithyroid agent that inhibits the actions of thyroid peroxidase, leading to a reduction in thyroid hormone synthesis and amelioration of hyperthyroidism.
ThioridazineA phenothiazine antipsychotic used to treat schizophrenia and generalized anxiety disorder.
TioconazoleAn imidazole antifungal used to treat vulvovaginal candidiasis.
ZafirlukastA leukotriene receptor antagonist used for prophylaxis and chronic treatment of asthma.
DiethylstilbestrolUsed in the treatment of prostate cancer. Previously used in the prevention of miscarriage or premature delivery in pregnant women prone to miscarriage or premature delivery.
IndisulamInvestigated for use/treatment in lung cancer.
AldesleukinA recombinant analog of interleukin-2 used to induce an adaptive immune response in the treatment of renal cell carcinoma.
ClonazepamA long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, and seizures.
DiazepamA long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures.
FlunitrazepamA benzodiazepine used to manage anxiety disorders and insomnia.
NitrazepamA long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, insomnia, and seizures.
Ellagic acidEllagic acid is being investigated for use in follicular lymphoma, brain injury in intrauterine growth restricted babies, obese adolescents, and solar lentigines.
DiacereinAn slow-onset anthraquinone IL-1 inhibitor used in the treatment of degenerative joint diseases like osteoarthritis.
AzelastineA histamine H1-receptor antagonist used intranasally to treat allergic and vasomotor rhinitis and in an ophthalmic solution to treat allergic conjunctivitis.
DexfenfluramineFor the management of obesity including weight loss and maintenance of weight loss in patients on a reduced calorie diet
MethotrimeprazineA phenothiazine used in the management of psychosis, particular those of schizophrenia, and manic phases of bipolar disorder.
VayarinADHD in children, hypertriglyceridemia [L1502, L1503].
DitiocarbA chelating agent that has been used to mobilize toxic metals from the tissues of man and experimental animals. It is the main metabolite of DISULFIRAM.
NiacinA B vitamin used to treat hypertriglyceridemia and pellagra.
OrphenadrineA muscarinic antagonist used as an adjunct for the symptomatic relief of musculoskeletal pain and discomfort.
OsilodrostatAn oral inhibitor of cortisol synthesis used to treat Cushing's disease by normalizing hypercortisolism.
FavipiravirAn antiviral used to manage influenza, and that has the potential to target other viral infections.
ClascoteroneAn androgen receptor antagonist used for the topical treatment of acne vulgaris in patients 12 years of age and older.
MenadioneThe primary known function of vitamin K is to assist in the normal clotting of blood, but it may also play a role in normal bone calcification.
RilpivirineA non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1).
EthambutolAn antituberculosis agent used in the prophylaxis and treatment of tuberculosis (TB).
DiosminA citrus flavonoid medication used to support vascular health.
QuercetinA natural flavonoid found in foods and natural supplement products.
CannabidiolAn active cannabinoid used as an adjunctive treatment for the management of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome and symptomatic relief of moderate to severe neuropathic pain or other painful conditions, like cancer.
CannabinolCannabinol (CBN) is a physiologically inactive constituent of Cannabis sativa.
Medical CannabisThe use of the plant species Cannabis sativa and Cannabis indica, popularly known as marijuana, has gained popularity in recent years for the management of a wide variety of medical...
CariprazineAn atypical antipsychotic used to treat schizophrenia and acute manic or mixed episodes due to bipolar I disorder.
Drugs & Drug Targets
DrugTargetType
DisulfiramAldehyde dehydrogenase, mitochondrialtarget
DisulfiramCytochrome P450 2E1enzyme
DisulfiramDopamine beta-hydroxylasetarget
DisulfiramCytochrome P450 3A4enzyme
DisulfiramCytochrome P450 3A5enzyme
DisulfiramBile salt export pumptransporter
MidostaurinProtein kinase C alpha typetarget
MidostaurinVascular endothelial growth factor receptor 2target
MidostaurinMast/stem cell growth factor receptor Kittarget
MidostaurinPlatelet-derived growth factor receptor alphatarget
MidostaurinPlatelet-derived growth factor receptor betatarget
MidostaurinReceptor-type tyrosine-protein kinase FLT3target
MidostaurinCytochrome P450 3A Subfamilyenzyme
MidostaurinCytochrome P450 1A2enzyme
MidostaurinCytochrome P450 2B6enzyme
MidostaurinCytochrome P450 2C8enzyme
MidostaurinCytochrome P450 2C9enzyme
MidostaurinCytochrome P450 2C19enzyme
MidostaurinCytochrome P450 2D6enzyme
MidostaurinCytochrome P450 2E1enzyme
MidostaurinCytochrome P450 3A4enzyme
MidostaurinCytochrome P450 3A5enzyme
MidostaurinCytochrome P450 3A7enzyme
MidostaurinCytochrome P450 3A43enzyme
IsoniazidCatalase-peroxidasetarget
IsoniazidEnoyl-[acyl-carrier-protein] reductase [NADH]target
IsoniazidCytochrome P450 2E1enzyme
IsoniazidCytochrome P450 1A2enzyme
IsoniazidCytochrome P450 2C9enzyme
IsoniazidCytochrome P450 2D6enzyme
IsoniazidCytochrome P450 2C19enzyme
IsoniazidArylamine N-acetyltransferase 2enzyme
IsoniazidArylamine N-acetyltransferaseenzyme
IsoniazidCytochrome P450 2A6enzyme
IsoniazidCytochrome P450 2C8enzyme
IsoniazidCytochrome P450 2C8target
IsoniazidCytochrome P450 1A2target
IsoniazidCytochrome P450 3A4target
IsoniazidCytochrome P450 2C19target
IsoniazidDihydrofolate reductasetarget
IsoniazidSerum albumincarrier
IsoniazidCytochrome P450 3A4enzyme
ClotrimazoleIntermediate conductance calcium-activated potassium channel protein 4target
ClotrimazoleCytochrome P450 2D6enzyme
ClotrimazoleCytochrome P450 2C8enzyme
ClotrimazoleCytochrome P450 3A4enzyme
ClotrimazoleCytochrome P450 2B6enzyme
ClotrimazoleP-glycoprotein 1transporter
ClotrimazoleCytochrome P450 2A6enzyme
ClotrimazoleCytochrome P450 2C9enzyme
ClotrimazoleCytochrome P450 2E1enzyme
ClotrimazoleCytochrome P450 3A7enzyme
ClotrimazoleCytochrome P450 51target
ClotrimazoleNuclear receptor subfamily 1 group I member 2target
ClotrimazoleHydroxycarboxylic acid receptor 2target
ClotrimazoleBile salt export pumptransporter
ClotrimazoleSolute carrier organic anion transporter family member 1B1transporter
ClotrimazoleSolute carrier organic anion transporter family member 1B3transporter
ClotrimazoleErgosteroltarget
RheinOxysterols receptor LXR-alphatarget
RheinOxysterols receptor LXR-betatarget
RheinArylamine N-acetyltransferasetarget
RheinArachidonate 5-lipoxygenasetarget
RheinCytochrome P450 1A2enzyme
RheinCytochrome P450 3A Subfamilyenzyme
RheinCytochrome P450 2E1enzyme
RheinCytochrome P450 2C9enzyme
RheinCytochrome P450 2D6enzyme
ZucapsaicinTransient receptor potential cation channel subfamily V member 1target
ZucapsaicinCytochrome P450 1A2enzyme
ZucapsaicinCytochrome P450 2C19enzyme
ZucapsaicinCytochrome P450 2C9enzyme
ZucapsaicinCytochrome P450 2E1enzyme
NabiloneCannabinoid receptor 2target
NabiloneCannabinoid receptor 1target
NabiloneCytochrome P450 2E1enzyme
NabiloneCytochrome P450 2C8enzyme
NabiloneCytochrome P450 2C9enzyme
NabiloneCytochrome P450 3A4enzyme
NabiloneCytochrome P450 2J2enzyme
TiclopidineP2Y purinoceptor 12target
TiclopidineCytochrome P450 2C19enzyme
TiclopidineCytochrome P450 2B6enzyme
TiclopidineCytochrome P450 2C9enzyme
TiclopidineCytochrome P450 2D6enzyme
TiclopidineMyeloperoxidaseenzyme
TiclopidineCytochrome P450 1A2enzyme
TiclopidineCytochrome P450 2C8enzyme
TiclopidineCytochrome P450 2E1enzyme
NifedipineCytochrome P450 3A4enzyme
NifedipineCytochrome P450 2E1enzyme
NifedipineCytochrome P450 2D6enzyme
NifedipineCalmodulintarget
NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
NifedipineVoltage-dependent L-type calcium channel subunit beta-2target
NifedipinePotassium voltage-gated channel subfamily D member 3target
NifedipineVoltage-dependent T-type calcium channeltarget
NifedipineCytochrome P450 1A2enzyme
NifedipineCytochrome P450 2A6enzyme
NifedipineCytochrome P450 2C8enzyme
NifedipineCanalicular multispecific organic anion transporter 2transporter
NifedipineP-glycoprotein 1transporter
NifedipineCanalicular multispecific organic anion transporter 1transporter
NifedipineCytochrome P450 1A1enzyme
NifedipineCytochrome P450 2B6enzyme
NifedipineNuclear receptor subfamily 1 group I member 2target
NifedipineSolute carrier organic anion transporter family member 1B1transporter
NifedipineBile salt export pumptransporter
NifedipineCytochrome P450 2C9enzyme
NifedipineSerum albumincarrier
Nifedipinealpha1-acid glycoproteincarrier
NifedipineCytochrome P450 3A5enzyme
RufinamideMetabotropic glutamate receptor 5target
RufinamideLiver carboxylesterase 1enzyme
RufinamideSodium channel protein type 9 subunit alphatarget
RufinamideSerum albumincarrier
RufinamideCytochrome P450 2E1enzyme
RufinamideCytochrome P450 3A4enzyme
EconazoleCytochrome P450 19A1enzyme
EconazoleCytochrome P450 2E1enzyme
EconazoleCytochrome P450 3A4enzyme
EconazoleCytochrome P450 51target
EconazoleNuclear receptor subfamily 1 group I member 2target
MiconazoleCytochrome P450 2C9enzyme
MiconazoleCytochrome P450 2D6enzyme
MiconazoleCytochrome P450 3A4enzyme
MiconazoleP-glycoprotein 1transporter
MiconazoleCytochrome P450 51target
MiconazoleNitric oxide synthase, endothelialtarget
MiconazoleNitric oxide synthase, inducibletarget
MiconazoleCytochrome P450 11B1, mitochondrialenzyme
MiconazoleCytochrome P450 2A6enzyme
MiconazoleCytochrome P450 2B6enzyme
MiconazoleCytochrome P450 2C19enzyme
MiconazoleCytochrome P450 2E1enzyme
MiconazoleNuclear receptor subfamily 1 group I member 2target
MiconazoleLanosterol 14-alpha demethylaseenzyme
MiconazoleCytochrome P450 19A1enzyme
MiconazoleCalcium-activated potassium channeltarget
MiconazoleVoltage-gated Potassium Channelstarget
MiconazoleInward rectifier potassium channeltarget
MiconazoleVoltage gated L-type calcium channeltarget
MiconazoleSerum albumincarrier
MiconazoleCytochrome P450 2C8enzyme
NicotineNeuronal acetylcholine receptor subunit alpha-2target
NicotineNeuronal acetylcholine receptor subunit beta-2target
NicotineNeuronal acetylcholine receptor subunit alpha-7target
NicotineNeuronal acetylcholine receptor subunit alpha-4target
NicotineNeuronal acetylcholine receptor subunit alpha-10target
NicotineNeuronal acetylcholine receptor subunit alpha-9target
NicotineCytochrome P450 2A6enzyme
NicotineCytochrome P450 2E1enzyme
NicotineCytochrome P450 2A13enzyme
NicotineCytochrome P450 2B6enzyme
NicotineNeuronal acetylcholine receptor subunit beta-4target
NicotineNeuronal acetylcholine receptor subunit alpha-3target
NicotineNeuronal acetylcholine receptor subunit alpha-5target
NicotineNeuronal acetylcholine receptor subunit alpha-6target
NicotineNeuronal acetylcholine receptor subunit beta-3target
NicotineSolute carrier family 22 member 2transporter
NicotineSolute carrier family 22 member 1transporter
NicotineSolute carrier family 22 member 3transporter
NicotineSolute carrier family 22 member 5transporter
NicotineSolute carrier family 22 member 4transporter
NicotineCytochrome P450 1A1enzyme
NicotineCytochrome P450 1A2enzyme
NicotineCytochrome P450 2C19enzyme
NicotineCytochrome P450 2C8enzyme
NicotineCytochrome P450 2C9enzyme
NicotineCytochrome P450 2D6enzyme
NicotineCytochrome P450 3A4enzyme
NicotineAmine oxidase [flavin-containing] Aenzyme
NicotineAmine oxidase [flavin-containing] Benzyme
NicotineCytochrome P450 19A1target
NicotineCholine O-acetyltransferasetarget
ChlorzoxazoneCalcium-activated potassium channel subunit alpha-1target
ChlorzoxazoneCytochrome P450 2E1enzyme
ChlorzoxazoneCytochrome P450 1A2enzyme
ChlorzoxazoneCytochrome P450 2A6enzyme
ChlorzoxazoneCytochrome P450 1A1enzyme
ChlorzoxazoneCytochrome P450 2D6enzyme
ChlorzoxazoneCytochrome P450 3A4enzyme
FomepizoleAlcohol dehydrogenase 1Atarget
FomepizoleAlcohol dehydrogenase 1Btarget
FomepizoleAlcohol dehydrogenase 1Ctarget
FomepizoleCatalasetarget
FomepizoleCytochrome P450 2E1enzyme
FomepizoleCytochrome P450 2A6enzyme
AdemetionineGlycine N-methyltransferasetarget
AdemetionineS-adenosylmethionine decarboxylase proenzymetarget
AdemetionineS-adenosylmethionine synthase isoform type-2target
AdemetionineCystathionine beta-synthasetarget
AdemetionineS-adenosylmethionine synthase isoform type-1target
AdemetionineCytochrome P450 2E1enzyme
AdemetionineCatechol O-methyltransferasetarget
AdemetionineSpermidine synthaseenzyme
AdemetionineCap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1target
AdemetionineArsenite methyltransferasetarget
PropofolCytochrome P450 2B6enzyme
PropofolUDP-glucuronosyltransferase 1-1enzyme
PropofolUDP-glucuronosyltransferase 1-9enzyme
PropofolGamma-aminobutyric acid receptor subunit beta-2target
PropofolGamma-aminobutyric acid receptor subunit beta-3target
PropofolSerum albumincarrier
PropofolSodium channel protein type 4 subunit alphatarget
PropofolSodium channel protein type 2 subunit alphatarget
PropofolFatty-acid amide hydrolase 1enzyme
PropofolCytochrome P450 2C9enzyme
PropofolUDP-glucuronosyltransferase 1-8enzyme
PropofolCytochrome P450 2E1enzyme
PropofolCytochrome P450 1B1enzyme
PropofolCytochrome P450 1A1enzyme
PropofolCytochrome P450 1A2enzyme
PropofolCytochrome P450 2C18enzyme
PropofolCytochrome P450 2C19enzyme
PropofolCytochrome P450 2C8enzyme
PropofolUDP-glucuronosyltransferase 1-6enzyme
PropofolGABA(A) Receptortarget
PropofolP-glycoprotein 1transporter
Alosetron5-hydroxytryptamine receptor 3Atarget
AlosetronCytochrome P450 1A2enzyme
AlosetronCytochrome P450 2C9enzyme
AlosetronCytochrome P450 3A4enzyme
AlosetronCytochrome P450 2E1enzyme
BifonazoleCytochrome P450 2B6target
BifonazoleCytochrome P450 51target
BifonazoleCytochrome P450 19A1enzyme
BifonazoleCytochrome P450 2E1enzyme
BifonazoleCytochrome P450 3A4enzyme
BromazepamCytochrome P450 1A2enzyme
BromazepamCytochrome P450 2C19enzyme
BromazepamCytochrome P450 2E1enzyme
BromazepamGABA(A) Receptortarget
BromazepamGABA(A) Receptor Benzodiazepine Binding Sitetarget
ChlorpromazineDopamine D2 receptortarget
Chlorpromazine5-hydroxytryptamine receptor 2Atarget
ChlorpromazineCytochrome P450 2D6enzyme
ChlorpromazineCholinesteraseenzyme
ChlorpromazineCytochrome P450 1A2enzyme
ChlorpromazineSerum albumincarrier
ChlorpromazineP-glycoprotein 1transporter
ChlorpromazineDopamine D1 receptortarget
Chlorpromazine5-hydroxytryptamine receptor 1Atarget
ChlorpromazineAlpha-1A adrenergic receptortarget
ChlorpromazineAlpha-1B adrenergic receptortarget
ChlorpromazineCytochrome P450 2E1enzyme
ChlorpromazineCytochrome P450 3A4enzyme
ChlorpromazineHistamine H1 receptortarget
ChlorpromazinePotassium voltage-gated channel subfamily H member 2target
ChlorpromazineD(1) dopamine receptortarget
ChlorpromazineDopamine D3 receptortarget
ChlorpromazineDopamine D4 receptortarget
ChlorpromazineDopamine D5 receptortarget
Chlorpromazine5-hydroxytryptamine receptor 2Ctarget
Chlorpromazine5-hydroxytryptamine 2 receptortarget
ChlorpromazineAlpha-1 adrenergic receptorstarget
ChlorpromazineAlpha-2 adrenergic receptorstarget
ChlorpromazineMuscarinic acetylcholine receptor M1target
ChlorpromazineMuscarinic acetylcholine receptor M3target
ChlorpromazineSphingomyelin phosphodiesterasetarget
ChlorpromazineCalmodulintarget
Chlorpromazinealpha1-acid glycoproteintarget
Chlorpromazine5-hydroxytryptamine receptor 6target
Chlorpromazine5-hydroxytryptamine receptor 7target
ChlorpromazineHistamine H4 receptortarget
ChlorpromazineBile salt export pumptransporter
CimetidineHistamine H2 receptortarget
CimetidineCytochrome P450 1A2enzyme
CimetidineCytochrome P450 2D6enzyme
CimetidineCytochrome P450 2C19enzyme
CimetidineCytochrome P450 3A4enzyme
CimetidineCytochrome P450 3A5enzyme
CimetidineP-glycoprotein 1transporter
CimetidineSolute carrier family 22 member 2transporter
CimetidineSolute carrier family 22 member 1transporter
CimetidineSolute carrier family 22 member 3transporter
CimetidineSolute carrier family 22 member 5transporter
CimetidineSolute carrier family 22 member 6transporter
CimetidineSolute carrier family 22 member 8transporter
CimetidineMultidrug and toxin extrusion protein 1transporter
CimetidineSolute carrier family 22 member 4transporter
CimetidineSolute carrier family 22 member 11transporter
CimetidineSolute carrier family 22 member 7transporter
CimetidineCytochrome P450 11B1, mitochondrialenzyme
CimetidineCytochrome P450 2C8enzyme
CimetidineCytochrome P450 2C9enzyme
CimetidineCytochrome P450 2E1enzyme
CimetidineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
CimetidineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
CimetidineBile salt export pumptransporter
CimetidineMultidrug and toxin extrusion protein 2transporter
CimetidineSerum albumincarrier
DesipramineMuscarinic acetylcholine receptor M1target
DesipramineSodium-dependent noradrenaline transportertarget
DesipramineBeta-2 adrenergic receptortarget
DesipramineMuscarinic acetylcholine receptor M2target
DesipramineSodium-dependent serotonin transportertarget
DesipramineHistamine H1 receptortarget
DesipramineBeta-1 adrenergic receptortarget
DesipramineCytochrome P450 2D6enzyme
DesipramineMuscarinic acetylcholine receptor M3target
DesipramineMuscarinic acetylcholine receptor M4target
DesipramineMuscarinic acetylcholine receptor M5target
DesipramineAlpha-1 adrenergic receptorstarget
Desipramine5-hydroxytryptamine receptor 2Atarget
DesipramineAlpha-1-acid glycoprotein 1carrier
DesipramineCytochrome P450 2B6enzyme
DesipramineCytochrome P450 3A4enzyme
DesipramineSolute carrier family 22 member 2transporter
DesipramineSolute carrier family 22 member 1transporter
DesipramineSolute carrier family 22 member 3transporter
DesipramineSolute carrier family 22 member 5transporter
DesipramineP-glycoprotein 1transporter
DesipramineSolute carrier family 22 member 4transporter
DesipramineCytochrome P450 1A2enzyme
DesipramineCytochrome P450 2E1enzyme
DesipramineSphingomyelin phosphodiesterasetarget
Desipramine5-hydroxytryptamine receptor 1Atarget
Desipramine5-hydroxytryptamine receptor 2Ctarget
DesipramineDopamine D2 receptortarget
DesipramineAlpha-2 adrenergic receptorstarget
DiclofenacProstaglandin G/H synthase 1target
DiclofenacProstaglandin G/H synthase 2target
DiclofenacTransthyretincarrier
DiclofenacCytochrome P450 2C9enzyme
DiclofenacCytochrome P450 2C19enzyme
DiclofenacCytochrome P450 1A2enzyme
DiclofenacCytochrome P450 2C8enzyme
DiclofenacSerum albumincarrier
DiclofenacMultidrug resistance-associated protein 4transporter
DiclofenacMultidrug resistance-associated protein 1transporter
DiclofenacSolute carrier family 22 member 6transporter
DiclofenacSolute carrier family 22 member 8transporter
DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DiclofenacSolute carrier family 22 member 11transporter
DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DiclofenacCytochrome P450 3A4enzyme
DiclofenacCytochrome P450 2B6enzyme
DiclofenacCytochrome P450 2C18enzyme
DiclofenacCytochrome P450 2E1enzyme
DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DiclofenacBile salt export pumptransporter
DiclofenacUDP-glucuronosyltransferase 1-3enzyme
DiclofenacUDP-glucuronosyltransferase 1-9enzyme
DiclofenacUDP-glucuronosyltransferase 2B4enzyme
DiclofenacArachidonate 5-lipoxygenaseenzyme
DiclofenacSodium channel protein type 4 subunit alphatransporter
DiclofenacAcid-sensing ion channel 1transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 2transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 3transporter
DiclofenacPhospholipase A2, membrane associatedenzyme
DiclofenacP-glycoprotein 1transporter
EtoricoxibProstaglandin G/H synthase 2target
EtoricoxibCytochrome P450 3A4enzyme
EtoricoxibCytochrome P450 2C9enzyme
EtoricoxibCytochrome P450 2D6enzyme
EtoricoxibCytochrome P450 1A2enzyme
EtoricoxibCytochrome P450 2C19enzyme
EtoricoxibCytochrome P450 2E1enzyme
FluphenazineDopamine D2 receptortarget
FluphenazineCalmodulintarget
FluphenazineDopamine D1 receptortarget
FluphenazineCytochrome P450 2D6enzyme
FluphenazineP-glycoprotein 1transporter
FluphenazineCytochrome P450 2E1enzyme
FluphenazineAndrogen receptortarget
Fluphenazine5-hydroxytryptamine receptor 2Atarget
Fluphenazine5-hydroxytryptamine receptor 2Ctarget
FlurazepamCytochrome P450 3A4enzyme
FlurazepamP-glycoprotein 1transporter
FlurazepamCytochrome P450 2E1enzyme
FlurazepamCytochrome P450 2A6enzyme
FlurazepamSolute carrier family 22 member 2transporter
FlurazepamGABA(A) Receptortarget
FlurazepamGABA(A) Receptor Benzodiazepine Binding Sitetarget
ImipramineSodium-dependent noradrenaline transportertarget
ImipramineSodium-dependent serotonin transportertarget
ImipramineCytochrome P450 1A2enzyme
ImipramineCytochrome P450 2C19enzyme
ImipramineCytochrome P450 2D6enzyme
ImipramineHistamine H1 receptortarget
ImipramineAlpha-1A adrenergic receptortarget
Imipramine5-hydroxytryptamine receptor 2Atarget
ImipramineMuscarinic acetylcholine receptor M1target
ImipramineMuscarinic acetylcholine receptor M2target
ImipramineMuscarinic acetylcholine receptor M3target
ImipramineMuscarinic acetylcholine receptor M4target
ImipramineMuscarinic acetylcholine receptor M5target
ImipraminePotassium voltage-gated channel subfamily D member 2target
ImipraminePotassium voltage-gated channel subfamily D member 3target
ImipramineAlpha-1D adrenergic receptortarget
ImipramineAlpha-1-acid glycoprotein 1carrier
ImipramineSolute carrier family 22 member 2transporter
ImipramineSolute carrier family 22 member 3transporter
ImipramineP-glycoprotein 1transporter
ImipramineSolute carrier family 22 member 4transporter
ImipramineCytochrome P450 3A4enzyme
ImipramineCytochrome P450 2B6enzyme
ImipramineCytochrome P450 2C18enzyme
ImipramineCytochrome P450 2E1enzyme
ImipramineCytochrome P450 3A7enzyme
Imipramine5-hydroxytryptamine receptor 2Ctarget
ImipramineAlpha-1B adrenergic receptortarget
Imipramine5-hydroxytryptamine receptor 7target
ImipramineD(1) dopamine receptortarget
ImipramineDopamine D2 receptortarget
ImipraminePotassium voltage-gated channel subfamily H member 2target
ImipramineSodium-dependent dopamine transportertarget
Imipramine5-hydroxytryptamine receptor 1Atarget
Imipramine5-hydroxytryptamine receptor 6target
ImipraminePotassium voltage-gated channel subfamily H member 1target
ImipramineSerum albumincarrier
ImipramineAlpha-1-acid glycoprotein 2target
Isosorbide dinitrateAtrial natriuretic peptide receptor 1target
Isosorbide dinitrateCytochrome P450 2E1enzyme
ItraconazoleLanosterol 14-alpha demethylasetarget
ItraconazoleLanosterol 14-alpha demethylasetarget
ItraconazoleCytochrome P450 3A4enzyme
ItraconazoleCytochrome P450 3A5enzyme
ItraconazoleCytochrome P450 3A7enzyme
ItraconazoleCytochrome P450 2B6enzyme
ItraconazoleP-glycoprotein 1transporter
ItraconazoleCytochrome P450 1A1enzyme
ItraconazoleCytochrome P450 2E1enzyme
ItraconazoleSolute carrier organic anion transporter family member 2B1transporter
ItraconazoleCytochrome P450 3A Subfamilyenzyme
MetyraponeCamphor 5-monooxygenasetarget
MetyraponeCytochrome P450 11B2, mitochondrialenzyme
MetyraponeCytochrome P450 2A6enzyme
MetyraponeCytochrome P450 3A4enzyme
MetyraponeCanalicular multispecific organic anion transporter 2transporter
MetyraponeCytochrome P450 11B1, mitochondrialtarget
MetyraponeCytochrome P450 11B1, mitochondrialenzyme
MetyraponeCytochrome P450 2E1enzyme
NicotinamideNAD-dependent protein deacylase sirtuin-5, mitochondrialtarget
NicotinamideADP-ribosyl cyclase 2target
NicotinamideExotoxin Atarget
NicotinamideL-lactate dehydrogenase A chaintarget
NicotinamidePoly [ADP-ribose] polymerase 1target
NicotinamideCytochrome P450 2D6enzyme
NicotinamideCytochrome P450 2E1enzyme
NicotinamideCytochrome P450 3A4enzyme
NortriptylineSodium-dependent serotonin transportertarget
NortriptylineSodium-dependent noradrenaline transportertarget
NortriptylineCytochrome P450 1A2enzyme
NortriptylineCytochrome P450 2D6enzyme
NortriptylineSerum albumincarrier
NortriptylineAlpha-1-acid glycoprotein 1carrier
NortriptylineHistamine H1 receptortarget
Nortriptyline5-hydroxytryptamine receptor 2Atarget
NortriptylineAlpha-1A adrenergic receptortarget
Nortriptyline5-hydroxytryptamine receptor 1Atarget
NortriptylineCytochrome P450 3A4enzyme
NortriptylineCytochrome P450 3A5enzyme
NortriptylineAlpha-1D adrenergic receptortarget
NortriptylineCytochrome P450 2C19enzyme
NortriptylineCytochrome P450 2E1enzyme
Nortriptyline5-hydroxytryptamine receptor 2Ctarget
NortriptylineAlpha-1B adrenergic receptortarget
NortriptylineAlpha-2 adrenergic receptorstarget
NortriptylineBeta adrenergic receptortarget
NortriptylineDopamine D2 receptortarget
NortriptylineSigma receptortarget
Nortriptyline5-hydroxytryptamine receptor 1Ctarget
NortriptylineSodium-dependent noradrenaline transportertransporter
NortriptylineMuscarinic acetylcholine receptortarget
NortriptylineP-glycoprotein 1transporter
SildenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
SildenafilCytochrome P450 2C9enzyme
SildenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
SildenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
SildenafilCytochrome P450 3A4enzyme
SildenafilCytochrome P450 3A5enzyme
SildenafilCytochrome P450 3A7enzyme
SildenafilMultidrug resistance-associated protein 4transporter
SildenafilMultidrug resistance-associated protein 5transporter
SildenafilMultidrug resistance-associated protein 7transporter
SildenafilCytochrome P450 2C19enzyme
SildenafilCytochrome P450 2D6enzyme
SildenafilCytochrome P450 2E1enzyme
SildenafilSolute carrier organic anion transporter family member 1B1transporter
SildenafilP-glycoprotein 1transporter
SildenafilOrnithine decarboxylasetarget
SildenafilProgrammed cell death 1 ligand 1target
Tegaserod5-hydroxytryptamine receptor 4target
Tegaserod5-hydroxytryptamine receptor 2Btarget
Tegaserod5-hydroxytryptamine receptor 2Ctarget
Tegaserod5-hydroxytryptamine receptor 2Atarget
TegaserodSodium-dependent serotonin transportertransporter
TegaserodCytochrome P450 1A2enzyme
TegaserodCytochrome P450 2C8enzyme
TegaserodCytochrome P450 2D6enzyme
TegaserodCytochrome P450 2E1enzyme
TegaserodATP-binding cassette sub-family G member 2transporter
TegaserodP-glycoprotein 1transporter
MethimazoleThyroid peroxidasetarget
MethimazoleCytochrome P450 1A2enzyme
MethimazoleCytochrome P450 2A6enzyme
MethimazoleCytochrome P450 2B6enzyme
MethimazoleCytochrome P450 2C19enzyme
MethimazoleCytochrome P450 2C9enzyme
MethimazoleCytochrome P450 2D6enzyme
MethimazoleCytochrome P450 2E1enzyme
MethimazoleCytochrome P450 3A4enzyme
MethimazoleDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
ThioridazineAlpha-1A adrenergic receptortarget
ThioridazineDopamine D2 receptortarget
Thioridazine5-hydroxytryptamine receptor 2Atarget
ThioridazineDopamine D1 receptortarget
ThioridazineCytochrome P450 2C19enzyme
ThioridazineCytochrome P450 2D6enzyme
ThioridazineAlpha-1B adrenergic receptortarget
ThioridazinePotassium voltage-gated channel subfamily H member 2target
ThioridazineCytochrome P450 2E1enzyme
TioconazoleLanosterol 14-alpha demethylasetarget
TioconazoleCytochrome P450 19A1enzyme
TioconazoleCytochrome P450 2C19enzyme
TioconazoleCytochrome P450 2E1enzyme
TioconazoleCytochrome P450 3A4enzyme
TioconazoleCytochrome P450 51target
ZafirlukastCysteinyl leukotriene receptor 1target
ZafirlukastCytochrome P450 2C9enzyme
ZafirlukastCytochrome P450 2C8enzyme
ZafirlukastProstaglandin G/H synthase 1enzyme
ZafirlukastCytochrome P450 3A4enzyme
ZafirlukastCytochrome P450 1A2enzyme
ZafirlukastCytochrome P450 2C19enzyme
ZafirlukastATP-binding cassette sub-family G member 2transporter
ZafirlukastCytochrome P450 2D6enzyme
DiethylstilbestrolEstrogen receptor alphatarget
DiethylstilbestrolEstrogen-related receptor gammatarget
DiethylstilbestrolTransthyretincarrier
DiethylstilbestrolCatechol O-methyltransferaseenzyme
DiethylstilbestrolCytochrome P450 19A1enzyme
DiethylstilbestrolATP-binding cassette sub-family G member 2transporter
DiethylstilbestrolP-glycoprotein 1transporter
DiethylstilbestrolEstrogen receptor betatarget
DiethylstilbestrolCytochrome P450 3A4enzyme
DiethylstilbestrolCytochrome P450 2C8enzyme
DiethylstilbestrolCytochrome P450 2C9enzyme
DiethylstilbestrolCytochrome P450 2E1enzyme
DiethylstilbestrolSteroid hormone receptor ERR1target
DiethylstilbestrolSteroid hormone receptor ERR2target
DiethylstilbestrolNuclear receptor coactivator 2target
DiethylstilbestrolNuclear receptor subfamily 1 group I member 2target
DiethylstilbestrolAndrogen receptortarget
DiethylstilbestrolSex hormone-binding globulintarget
DiethylstilbestrolSolute carrier organic anion transporter family member 1B1transporter
DiethylstilbestrolSolute carrier organic anion transporter family member 2B1transporter
DiethylstilbestrolBile salt export pumptransporter
IndisulamCytochrome P450 2C9enzyme
IndisulamCytochrome P450 3A4enzyme
IndisulamCytochrome P450 2E1enzyme
IndisulamCytochrome P450 2D6enzyme
AldesleukinInterleukin-2 receptor subunit betatarget
AldesleukinInterleukin-2 receptor subunit alphatarget
AldesleukinCytokine receptor common subunit gammatarget
AldesleukinProstaglandin G/H synthase 2enzyme
AldesleukinCytosolic phospholipase A2enzyme
AldesleukinCytochrome P450 3A4enzyme
AldesleukinXanthine dehydrogenase/oxidaseenzyme
AldesleukinCytochrome P450 2E1enzyme
ClonazepamCytochrome P450 3A4enzyme
ClonazepamSerum albumincarrier
ClonazepamCytochrome P450 2E1enzyme
ClonazepamArylamine N-acetyltransferase 2enzyme
ClonazepamGABA(A) Receptortarget
ClonazepamNuclear receptor subfamily 1 group I member 2target
ClonazepamGABA(A) Receptor Benzodiazepine Binding Sitetarget
DiazepamCytochrome P450 3A4enzyme
DiazepamSerum albumincarrier
DiazepamCytochrome P450 2C9enzyme
DiazepamCytochrome P450 2C19enzyme
DiazepamCytochrome P450 3A5enzyme
DiazepamCytochrome P450 3A7enzyme
DiazepamP-glycoprotein 1transporter
DiazepamCytochrome P450 2B6enzyme
DiazepamProstaglandin G/H synthase 1enzyme
DiazepamCytochrome P450 2C18enzyme
DiazepamCytochrome P450 2C8enzyme
DiazepamGABA(A) Receptortarget
DiazepamGABA(A) Receptor Benzodiazepine Binding Sitetarget
FlunitrazepamCytochrome P450 2C19enzyme
FlunitrazepamUDP-glucuronosyltransferase 2B7enzyme
FlunitrazepamCytochrome P450 2A6enzyme
FlunitrazepamCytochrome P450 2B6enzyme
FlunitrazepamCytochrome P450 2C9enzyme
FlunitrazepamCytochrome P450 3A4enzyme
FlunitrazepamCytochrome P450 2E1enzyme
FlunitrazepamUDP-glucuronosyltransferase 1-1enzyme
FlunitrazepamUDP-glucuronosyltransferase 1-3enzyme
FlunitrazepamGABA(A) Receptortarget
FlunitrazepamGABA(A) Receptor Benzodiazepine Binding Sitetarget
NitrazepamSodium channel protein type 1 subunit alphatarget
NitrazepamCytochrome P450 3A4enzyme
NitrazepamCytochrome P450 2E1enzyme
NitrazepamGABA(A) Receptortarget
NitrazepamGABA(A) Receptor Benzodiazepine Binding Sitetarget
Ellagic acidSolute carrier family 22 member 6transporter
Ellagic acidSolute carrier family 22 member 11transporter
Ellagic acidCytochrome P450 1A1enzyme
Ellagic acidCytochrome P450 2E1enzyme
Ellagic acidCarbonic anhydrase 1target
Ellagic acidCarbonic anhydrase 2target
Ellagic acidCarbonic anhydrase 3target
Ellagic acidCarbonic anhydrase 4target
Ellagic acidCarbonic anhydrase 5A, mitochondrialtarget
Ellagic acidCarbonic anhydrase 5B, mitochondrialtarget
Ellagic acidCarbonic anhydrase 6target
Ellagic acidCarbonic anhydrase 7target
Ellagic acidCarbonic anhydrase 9target
Ellagic acidCarbonic anhydrase 12target
Ellagic acidCarbonic anhydrase 14target
Ellagic acidCasein kinase II subunit alphatarget
Ellagic acidcAMP-dependent protein kinase catalytic subunit alphatarget
Ellagic acidProtein kinase C alpha typetarget
Ellagic acidProtein kinase C beta typetarget
Ellagic acidTyrosine-protein kinase SYKtarget
Ellagic acidSqualene monooxygenasetarget
DiacereinOxysterols receptor LXR-alphatarget
DiacereinOxysterols receptor LXR-betatarget
DiacereinArylamine N-acetyltransferasetarget
DiacereinArachidonate 5-lipoxygenasetarget
DiacereinCytochrome P450 1A2target
DiacereinCytochrome P450 3A Subfamilytarget
DiacereinCytochrome P450 2E1target
DiacereinCytochrome P450 2C9target
DiacereinCytochrome P450 2D6target
AzelastineHistamine H1 receptortarget
AzelastineCytochrome P450 1A2enzyme
AzelastineCytochrome P450 2D6enzyme
AzelastineCytochrome P450 3A4enzyme
AzelastineCytochrome P450 2C19enzyme
AzelastineCytochrome P450 1A1enzyme
AzelastineCytochrome P450 3A5enzyme
AzelastineCytochrome P450 2C9enzyme
AzelastineCytochrome P450 2C8enzyme
AzelastineP-glycoprotein 1transporter
AzelastineCytochrome P450 2A6enzyme
AzelastineCytochrome P450 2E1enzyme
AzelastineHistamine H2 receptortarget
AzelastinePhospholipase A2target
AzelastineLeukotriene C4 synthasetarget
AzelastineCytochrome P450 2B6enzyme
DexfenfluramineSodium-dependent serotonin transportertarget
Dexfenfluramine5-hydroxytryptamine receptor 2Ctarget
DexfenfluramineCytochrome P450 2D6enzyme
DexfenfluramineCytochrome P450 1A2enzyme
DexfenfluramineCytochrome P450 2E1enzyme
MethotrimeprazineDopamine D3 receptortarget
MethotrimeprazineHistamine H1 receptortarget
MethotrimeprazineMuscarinic acetylcholine receptor M1target
MethotrimeprazineMuscarinic acetylcholine receptor M2target
MethotrimeprazineMuscarinic acetylcholine receptor M3target
MethotrimeprazineMuscarinic acetylcholine receptor M4target
MethotrimeprazineMuscarinic acetylcholine receptor M5target
MethotrimeprazineAlpha-1A adrenergic receptortarget
MethotrimeprazineAlpha-1B adrenergic receptortarget
MethotrimeprazineAlpha-1D adrenergic receptortarget
MethotrimeprazineCytochrome P450 2D6enzyme
MethotrimeprazineDopamine D2 receptortarget
MethotrimeprazineDopamine D1 receptortarget
MethotrimeprazineDopamine D5 receptortarget
MethotrimeprazineDopamine D4 receptortarget
MethotrimeprazineAlpha-2A adrenergic receptortarget
MethotrimeprazineAlpha-2B adrenergic receptortarget
MethotrimeprazineAlpha-2C adrenergic receptortarget
Methotrimeprazine5-hydroxytryptamine receptor 2Atarget
Methotrimeprazine5-hydroxytryptamine receptor 2Ctarget
MethotrimeprazineCytochrome P450 2E1enzyme
VayarinCytochrome P450 2E1enzyme
VayarinFatty acid desaturase 1enzyme
VayarinElongation of very long chain fatty acids protein 4enzyme
VayarinPeroxisomal acyl-coenzyme A oxidase 1enzyme
DitiocarbCytochrome P450 2E1enzyme
DitiocarbCytochrome P450 3A4enzyme
DitiocarbCytochrome P450 3A5enzyme
NiacinHydroxycarboxylic acid receptor 2target
NiacinNicotinamide N-methyltransferasetarget
NiacinNicotinate-nucleotide pyrophosphorylase [carboxylating]target
NiacinHydroxycarboxylic acid receptor 3target
NiacinSolute carrier family 22 member 5transporter
NiacinSolute carrier organic anion transporter family member 2B1transporter
NiacinMonocarboxylate transporter 1transporter
NiacinCytochrome P450 2D6enzyme
NiacinSodium-coupled monocarboxylate transporter 1transporter
NiacinMonocarboxylate transporter 4transporter
NiacinThyroxine-binding globulincarrier
NiacinCytochrome P450 3A4enzyme
NiacinCytochrome P450 2E1enzyme
OrphenadrineGlutamate receptor ionotropic, NMDA 1target
OrphenadrineGlutamate receptor ionotropic, NMDA 2Dtarget
OrphenadrineGlutamate receptor ionotropic, NMDA 3Btarget
OrphenadrineGlutamate receptor ionotropic, NMDA 3Atarget
OrphenadrineHistamine H1 receptortarget
OrphenadrineCytochrome P450 2B6enzyme
OrphenadrineCytochrome P450 2E1enzyme
OrphenadrineCytochrome P450 3A4enzyme
OrphenadrineSodium-dependent noradrenaline transportertarget
OrphenadrineSodium channel protein type 10 subunit alphatarget
OrphenadrineCytochrome P450 1A2enzyme
OrphenadrineCytochrome P450 2D6enzyme
OrphenadrineSerum albumincarrier
OsilodrostatCytochrome P450 11B1, mitochondrialtarget
OsilodrostatCytochrome P450 11B2, mitochondrialtarget
OsilodrostatCytochrome P450 3A4enzyme
OsilodrostatCytochrome P450 2B6enzyme
OsilodrostatCytochrome P450 2D6enzyme
OsilodrostatUDP-glucuronosyltransferase 1-4enzyme
OsilodrostatUDP-glucuronosyltransferase 2B7enzyme
OsilodrostatUDP-glucuronosyltransferase 2B10enzyme
OsilodrostatCytochrome P450 3A5enzyme
OsilodrostatCytochrome P450 1A2enzyme
OsilodrostatCytochrome P450 2C19enzyme
OsilodrostatCytochrome P450 2E1enzyme
OsilodrostatUDP-glucuronosyltransferase 1A1enzyme
OsilodrostatSolute carrier organic anion transporter family member 1B1transporter
OsilodrostatSolute carrier family 22 member 1transporter
OsilodrostatSolute carrier family 22 member 2transporter
OsilodrostatSolute carrier family 22 member 6transporter
OsilodrostatSolute carrier family 22 member 8transporter
OsilodrostatMultidrug and toxin extrusion protein 1transporter
FavipiravirRNA-directed RNA polymerase catalytic subunittarget
FavipiravirAldehyde oxidaseenzyme
FavipiravirXanthine dehydrogenase/oxidaseenzyme
FavipiravirCytochrome P450 2C8enzyme
FavipiravirSerum albumincarrier
Favipiraviralpha1-acid glycoproteincarrier
FavipiravirP-glycoprotein 1transporter
FavipiravirSolute carrier family 22 member 6transporter
FavipiravirSolute carrier family 22 member 8transporter
FavipiravirSolute carrier family 22 member 12transporter
FavipiravirCytochrome P450 2E1enzyme
ClascoteroneAndrogen receptortarget
ClascoteroneCytochrome P450 1A2enzyme
ClascoteroneCytochrome P450 2B6enzyme
ClascoteroneCytochrome P450 2C8enzyme
ClascoteroneCytochrome P450 2C9enzyme
ClascoteroneCytochrome P450 2C19enzyme
ClascoteroneCytochrome P450 2D6enzyme
ClascoteroneCytochrome P450 2E1enzyme
ClascoteroneCytochrome P450 3A4enzyme
MenadioneProthrombintarget
MenadioneVitamin K epoxide reductase complex subunit 1target
MenadioneCoagulation factor IXtarget
MenadioneVitamin K-dependent gamma-carboxylasetarget
MenadioneVitamin K-dependent protein Ctarget
MenadioneVitamin K-dependent protein Starget
MenadioneNAD(P)H dehydrogenase [quinone] 1target
MenadioneRibosyldihydronicotinamide dehydrogenase [quinone]target
MenadioneVitamin K epoxide reductase complex subunit 1-like protein 1target
MenadioneXanthine dehydrogenase/oxidaseenzyme
MenadioneAldehyde oxidaseenzyme
MenadioneMethylenetetrahydrofolate reductaseenzyme
MenadioneCytochrome P450 1A1enzyme
MenadioneOsteocalcintarget
MenadioneCytochrome P450 1A2enzyme
MenadioneCytochrome P450 2A6enzyme
MenadioneCytochrome P450 1B1enzyme
MenadioneCytochrome P450 2B6enzyme
MenadioneCytochrome P450 2C8enzyme
MenadioneCytochrome P450 2C9enzyme
MenadioneCytochrome P450 2C19enzyme
MenadioneCytochrome P450 2D6enzyme
MenadioneCytochrome P450 2E1enzyme
MenadioneCytochrome P450 3A4enzyme
MenadioneCytochrome P450 3A5enzyme
MenadioneCytochrome P450 3A7enzyme
RilpivirineCytochrome P450 3A4enzyme
RilpivirineReverse transcriptase/RNaseHtarget
RilpivirineNuclear receptor subfamily 1 group I member 2target
RilpivirineCytochrome P450 2C19enzyme
RilpivirineCytochrome P450 2B6enzyme
RilpivirineP-glycoprotein 1transporter
RilpivirineATP-binding cassette sub-family G member 2transporter
RilpivirineSolute carrier organic anion transporter family member 1B1transporter
RilpivirineSolute carrier organic anion transporter family member 1B3transporter
RilpivirineSerum albumincarrier
RilpivirineCytochrome P450 2D6enzyme
RilpivirineCytochrome P450 2C9enzyme
RilpivirineCytochrome P450 2C8enzyme
RilpivirineCytochrome P450 2E1enzyme
EthambutolProbable arabinosyltransferase Btarget
EthambutolProbable arabinosyltransferase Atarget
EthambutolProbable arabinosyltransferase Ctarget
EthambutolCytochrome P450 1A2enzyme
EthambutolCytochrome P450 2E1enzyme
EthambutolCytochrome P450 2C19enzyme
EthambutolCytochrome P450 2D6enzyme
EthambutolCytochrome P450 2A6enzyme
EthambutolCytochrome P450 2C9enzyme
EthambutolCytochrome P450 3A4enzyme
DiosminAryl hydrocarbon receptortarget
DiosminSerum albumincarrier
DiosminP-glycoprotein 1transporter
DiosminSolute carrier organic anion transporter family member 1B1transporter
DiosminSolute carrier organic anion transporter family member 1B3transporter
DiosminSolute carrier organic anion transporter family member 2B1transporter
DiosminCytochrome P450 1A1enzyme
DiosminCytochrome P450 2C9enzyme
DiosminCytochrome P450 2E1enzyme
DiosminCytochrome P450 3A4enzyme
QuercetinTyrosine-protein kinase HCKtarget
QuercetinCytochrome P450 2C8enzyme
QuercetinMultidrug resistance-associated protein 1transporter
QuercetinCanalicular multispecific organic anion transporter 1transporter
QuercetinMonocarboxylate transporter 2transporter
QuercetinSolute carrier organic anion transporter family member 2B1transporter
QuercetinP-glycoprotein 1transporter
QuercetinMonocarboxylate transporter 1transporter
QuercetinATP-binding cassette sub-family G member 2transporter
QuercetinPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
QuercetinUDP-glucuronosyltransferase 3A1target
QuercetinATP synthase subunit alpha, mitochondrialtarget
QuercetinATP synthase subunit beta, mitochondrialtarget
QuercetinATP synthase subunit gamma, mitochondrialtarget
QuercetinSerine/threonine-protein kinase pim-1target
QuercetinHTH-type transcriptional regulator TtgRtarget
Quercetin3-hydroxyisobutyryl-CoA hydrolase, mitochondrialtarget
Quercetin3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZtarget
QuercetinSerine/threonine-protein kinase 17Btarget
QuercetinEstrogen receptor alphatarget
QuercetinEstrogen receptor betatarget
QuercetinRibosyldihydronicotinamide dehydrogenase [quinone]target
QuercetinSerum albumincarrier
QuercetinAryl hydrocarbon receptortarget
QuercetinCytochrome P450 1B1target
QuercetinActin, cytoplasmic 1target
QuercetinCasein kinase II subunit alphatarget
QuercetinCasein kinase II subunit betatarget
QuercetinEukaryotic translation initiation factor 3 subunit Ftarget
QuercetinHeat shock protein HSP 90-alphatarget
QuercetinHeat shock-related 70 kDa protein 2target
QuercetinRuvB-like 2target
QuercetinSplicing factor 3B subunit 3target
QuercetinUbiquitin-like modifier-activating enzyme 1target
QuercetinSex hormone-binding globulintarget
QuercetinCarbonyl reductase [NADPH] 1target
QuercetinCCAAT/enhancer-binding protein betatarget
QuercetinNuclear receptor subfamily 1 group I member 2target
QuercetinSolute carrier organic anion transporter family member 1B1transporter
QuercetinCytochrome P450 2C9enzyme
QuercetinCytochrome P450 1A2enzyme
QuercetinCytochrome P450 2E1enzyme
QuercetinCytochrome P450 2C19enzyme
QuercetinCytochrome P450 3A Subfamilyenzyme
QuercetinCytochrome P450 2D6enzyme
CannabidiolCytochrome P450 2C9enzyme
CannabidiolCytochrome P450 2C19enzyme
CannabidiolCytochrome P450 2D6enzyme
CannabidiolCytochrome P450 3A4enzyme
CannabidiolCannabinoid receptor 1target
CannabidiolCannabinoid receptor 2target
CannabidiolG-protein coupled receptor 12target
CannabidiolGlycine receptor subunit alpha-1target
CannabidiolGlycine receptor (alpha-1/beta)target
CannabidiolGlycine receptor subunit alpha-3target
CannabidiolN-arachidonyl glycine receptortarget
CannabidiolG-protein coupled receptor 55target
Cannabidiol5-hydroxytryptamine receptor 1Atarget
Cannabidiol5-hydroxytryptamine receptor 2Atarget
CannabidiolNeuronal acetylcholine receptor subunit alpha-7target
CannabidiolDelta-type opioid receptortarget
CannabidiolMu-type opioid receptortarget
CannabidiolPeroxisome proliferator-activated receptor gammatarget
CannabidiolCytochrome P450 3A5enzyme
CannabidiolArylalkylamine N-acetyltransferaseenzyme
CannabidiolCytochrome P450 1A1enzyme
CannabidiolFatty-acid amide hydrolase 1enzyme
CannabidiolArachidonate 5-lipoxygenaseenzyme
CannabidiolArachidonate 15-lipoxygenaseenzyme
CannabidiolQuinone oxidoreductaseenzyme
CannabidiolMultidrug resistance-associated protein 1transporter
CannabidiolATP-binding cassette sub-family G member 2transporter
CannabidiolEquilibrative nucleoside transporter 1transporter
CannabidiolTransient receptor potential cation channel subfamily V member 1target
CannabidiolVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
CannabidiolVoltage-dependent T-type calcium channel subunit alpha-1Htarget
CannabidiolVoltage-dependent T-type calcium channel subunit alpha-1Itarget
CannabidiolTransient receptor potential cation channel subfamily A member 1target
CannabidiolTransient receptor potential cation channel subfamily M member 8target
CannabidiolTransient receptor potential cation channel subfamily V member 2target
CannabidiolTransient receptor potential cation channel subfamily V member 3target
CannabidiolTransient receptor potential cation channel subfamily V member 4target
CannabidiolVoltage-dependent anion-selective channel protein 1target
Cannabidiol5-hydroxytryptamine receptor 3Atarget
CannabidiolAdenosine receptor A1target
CannabidiolProstaglandin G/H synthase 1target
CannabidiolProstaglandin G/H synthase 2target
CannabidiolAcetyl-CoA acetyltransferase, mitochondrialtarget
CannabidiolSteroid 17-alpha-hydroxylase/17,20 lyasetarget
Cannabidiol3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
CannabidiolGlutathione reductase, mitochondrialtarget
CannabidiolGlutathione peroxidase 1target
CannabidiolIndoleamine 2,3-dioxygenase 1target
CannabidiolCytochrome P450 1B1target
CannabidiolNAD(P)H dehydrogenase [quinone] 1target
CannabidiolCatalasetarget
CannabidiolCytochrome P450 3A5target
CannabidiolCytochrome P450 2D6target
CannabidiolSuperoxide dismutase [Cu-Zn]target
CannabidiolCytochrome P450 1A2target
CannabidiolCytochrome P450 3A7target
CannabidiolArylalkylamine N-acetyltransferasetarget
CannabidiolN-acylethanolamine-hydrolyzing acid amidasetarget
CannabidiolCytochrome P450 1A2enzyme
CannabidiolCytochrome P450 1B1enzyme
CannabidiolCytochrome P450 2A6enzyme
CannabidiolCytochrome P450 2B6enzyme
CannabidiolCytochrome P450 2C8enzyme
CannabidiolCytochrome P450 2E1enzyme
CannabidiolCytochrome P450 3A7enzyme
CannabidiolUDP-glucuronosyltransferase 1-7enzyme
CannabidiolUDP-glucuronosyltransferase 1-9enzyme
CannabidiolUDP-glucuronosyltransferase 2B7enzyme
CannabidiolUDP-glucuronosyltransferase 2B17enzyme
CannabidiolP-glycoprotein 1transporter
CannabidiolCytochrome P450 2J2enzyme
CannabidiolLiver carboxylesterase 1enzyme
CannabinolCytochrome P450 3A4enzyme
CannabinolCytochrome P450 2C19enzyme
CannabinolCytochrome P450 1A1enzyme
CannabinolCytochrome P450 1A2enzyme
CannabinolCytochrome P450 1B1enzyme
CannabinolCytochrome P450 2A6enzyme
CannabinolCytochrome P450 2B6enzyme
CannabinolCytochrome P450 2C9enzyme
CannabinolCytochrome P450 2D6enzyme
CannabinolCytochrome P450 3A5enzyme
CannabinolCytochrome P450 3A7enzyme
CannabinolUDP-glucuronosyltransferase 1-7enzyme
CannabinolUDP-glucuronosyltransferase 1-8enzyme
CannabinolUDP-glucuronosyltransferase 1-9enzyme
CannabinolUDP-glucuronosyltransferase 1-10enzyme
CannabinolUDP-glucuronosyltransferase 2B7enzyme
CannabinolP-glycoprotein 1transporter
CannabinolATP-binding cassette sub-family G member 2transporter
CannabinolMultidrug resistance-associated protein 1transporter
CannabinolCytochrome P450 2E1enzyme
CannabinolCytochrome P450 2J2enzyme
CannabinolLiver carboxylesterase 1enzyme
Medical CannabisCannabinoid receptor 1target
Medical CannabisCannabinoid receptor 2target
Medical CannabisCytochrome P450 2C9enzyme
Medical CannabisCytochrome P450 2C19enzyme
Medical CannabisCytochrome P450 2D6enzyme
Medical CannabisCytochrome P450 3A4enzyme
Medical CannabisG-protein coupled receptor 12target
Medical CannabisGlycine receptor subunit alpha-1target
Medical CannabisGlycine receptor (alpha-1/beta)target
Medical CannabisGlycine receptor subunit alpha-3target
Medical CannabisN-arachidonyl glycine receptortarget
Medical CannabisG-protein coupled receptor 55target
Medical Cannabis5-hydroxytryptamine receptor 1Atarget
Medical Cannabis5-hydroxytryptamine receptor 2Atarget
Medical CannabisNeuronal acetylcholine receptor subunit alpha-7target
Medical CannabisDelta-type opioid receptortarget
Medical CannabisMu-type opioid receptortarget
Medical CannabisPeroxisome proliferator-activated receptor gammatarget
Medical CannabisCytochrome P450 3A5enzyme
Medical CannabisCytochrome P450 3A7enzyme
Medical CannabisCytochrome P450 1A1enzyme
Medical CannabisCytochrome P450 1A2enzyme
Medical CannabisCytochrome P450 1B1enzyme
Medical CannabisArachidonate 5-lipoxygenaseenzyme
Medical CannabisArachidonate 15-lipoxygenaseenzyme
Medical CannabisSuperoxide dismutase [Cu-Zn]enzyme
Medical CannabisMultidrug resistance-associated protein 1transporter
Medical CannabisATP-binding cassette sub-family G member 2transporter
Medical CannabisEquilibrative nucleoside transporter 1transporter
Medical CannabisTransient receptor potential cation channel subfamily V member 1target
Medical CannabisVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
Medical CannabisVoltage-dependent T-type calcium channel subunit alpha-1Htarget
Medical CannabisVoltage-dependent T-type calcium channel subunit alpha-1Itarget
Medical CannabisTransient receptor potential cation channel subfamily A member 1target
Medical CannabisTransient receptor potential cation channel subfamily M member 8target
Medical CannabisTransient receptor potential cation channel subfamily V member 2target
Medical CannabisTransient receptor potential cation channel subfamily V member 3target
Medical CannabisTransient receptor potential cation channel subfamily V member 4target
Medical CannabisVoltage-dependent anion-selective channel protein 1target
Medical CannabisN-acyl-phosphatidylethanolamine-hydrolyzing phospholipase Dtarget
Medical CannabisN-acylethanolamine-hydrolyzing acid amidasetarget
Medical CannabisArylalkylamine N-acetyltransferasetarget
Medical CannabisPhospholipase A2target
Medical CannabisSuperoxide dismutase [Cu-Zn]target
Medical CannabisFatty-acid amide hydrolase 1target
Medical CannabisCatalasetarget
Medical CannabisQuinone oxidoreductasetarget
Medical CannabisSphingomyelin phosphodiesterasetarget
Medical CannabisGlutathione peroxidase 1target
Medical CannabisGlutathione reductase, mitochondrialtarget
Medical Cannabis3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
Medical CannabisIndoleamine 2,3-dioxygenase 1target
Medical CannabisProstaglandin G/H synthase 1target
Medical CannabisProstaglandin G/H synthase 2target
Medical CannabisSteroid 17-alpha-hydroxylase/17,20 lyasetarget
Medical CannabisAcetyl-CoA acetyltransferase, mitochondrialtarget
Medical CannabisCytochrome P450 2A6enzyme
Medical CannabisCytochrome P450 2B6enzyme
Medical CannabisCytochrome P450 2C8enzyme
Medical CannabisCytochrome P450 2E1enzyme
Medical CannabisCytochrome P450 2J2enzyme
Medical CannabisUDP-glucuronosyltransferase 1-7enzyme
Medical CannabisUDP-glucuronosyltransferase 1-8enzyme
Medical CannabisUDP-glucuronosyltransferase 1-9enzyme
Medical CannabisUDP-glucuronosyltransferase 1-10enzyme
Medical CannabisUDP-glucuronosyltransferase 2B17enzyme
Medical CannabisLiver carboxylesterase 1enzyme
Medical CannabisP-glycoprotein 1transporter
Medical CannabisUDP-glucuronosyltransferase 2B7enzyme
CariprazineCytochrome P450 3A4enzyme
CariprazineCytochrome P450 2D6enzyme
CariprazineP-glycoprotein 1transporter
CariprazineCytochrome P450 3A5enzyme
CariprazineDopamine D3 receptortarget
CariprazineDopamine D2 receptortarget
Cariprazine5-hydroxytryptamine receptor 1Atarget
Cariprazine5-hydroxytryptamine receptor 2Btarget
Cariprazine5-hydroxytryptamine receptor 2Atarget
CariprazineHistamine H1 receptortarget
Cariprazine5-hydroxytryptamine receptor 2Ctarget
CariprazineAlpha-1A adrenergic receptortarget
CariprazineCytochrome P450 1A2enzyme
CariprazineCytochrome P450 2C9enzyme
CariprazineCytochrome P450 2C19enzyme
CariprazineCytochrome P450 2E1enzyme