Disulfiram | A carbamate derivative used to treat alcohol addiction. |
Midostaurin | An antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL). |
Isoniazid | An antibiotic used to treat mycobacterial infections; most commonly use in combination with other antimycobacterial agents for the treatment of active or latent tuberculosis. |
Clotrimazole | A topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis. |
Rhein | No approved indication. |
Zucapsaicin | A topical analgesic used as an adjunct to relieve severe pain of osteoarthritis of the knee in selected adult patients. |
Nabilone | A synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy. |
Ticlopidine | A platelet aggregation inhibitor used in the prevention of conditions associated with thrombi, such as stroke and transient ischemic attacks (TIA). |
Nifedipine | A dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension. |
Rufinamide | An antiepileptic drug used as adjunctive therapy to treat seizures associated with Lennox-Gastaut Syndrome (LGS). |
Econazole | A topical antifungal used to treat tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis and tinea versicolor. |
Miconazole | An azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis. |
Nicotine | A stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation. |
Chlorzoxazone | A drug with muscle relaxant properties that is used as an adjunct to physical therapy and analgesics to treat stiffness and pain caused by a variety of musculoskeletal conditions. |
Fomepizole | An inhibitor of alcohol dehydrogenase used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. |
Ademetionine | S-Adenosylmethionine (SAMe) is used as a drug in Europe for the treatment of depression, liver disorders, fibromyalgia, and osteoarthritis. It has also been introduced into the United States market as... |
Propofol | A medication used in general anesthesia and for sedation. |
Alosetron | A 5-HT3 antagonist used to treat diarrhea-predominant IBS. |
Bifonazole | Used for the treatment of various topical fungal infections, including athlete's foot (tinea pedis). |
Bromazepam | A short-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and severe anxiety. |
Chlorpromazine | A phenothiazine antipsychotic used to treat nausea, vomiting, preoperative anxiety, schizophrenia, bipolar disorder, and severe behavioral problems in children. |
Cimetidine | A histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion. |
Desipramine | A tricyclic antidepressant used in the treatment of depression. |
Diclofenac | An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. |
Etoricoxib | For the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. |
Fluphenazine | A phenothiazine used to treat patients requiring long-term neuroleptic therapy. |
Flurazepam | A long-acting benzodiazepine with a rapid onset of action that is commonly used to treat insomnia. |
Imipramine | A tricyclic antidepressant indicated for the treatment of depression and to reduce childhood enuresis. |
Isosorbide dinitrate | A vasodilator used to treat angina in coronary artery disease. |
Itraconazole | An antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis. |
Metyrapone | A steroid 11-beta-monooxygenase inhibitor used to test hypothalamic-pituitary ACTH function. |
Nicotinamide | An ingredient found in a variety of cosmetic products. |
Nortriptyline | A tricyclic antidepressant used in the treatment of depression. |
Selegiline | A monoamine oxidase inhibitor used to treat major depressive disorder and Parkinson's. |
Sildenafil | A phosphodiesterase inhibitor used for the treatment of erectile dysfunction. |
Sulfanilamide | A sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans. |
Tegaserod | A serotonin-4 (5-HT4) receptor agonist indicated for the treatment of constipation predominant irritable bowel syndrome (IBS-C) specifically in women under the age of 65. There is currently no safety or efficacy data for use of tegaserol in men. |
Methimazole | A thionamide antithyroid agent that inhibits the actions of thyroid peroxidase, leading to a reduction in thyroid hormone synthesis and amelioration of hyperthyroidism. |
Thioridazine | A phenothiazine antipsychotic used to treat schizophrenia and generalized anxiety disorder. |
Tioconazole | An imidazole antifungal used to treat vulvovaginal candidiasis. |
Tranylcypromine | A monoamine oxidase inhibitor used to treat major depressive disorder. |
Zafirlukast | A leukotriene receptor antagonist used for prophylaxis and chronic treatment of asthma. |
Diethylstilbestrol | Used in the treatment of prostate cancer. Previously used in the prevention of miscarriage or premature delivery in pregnant women prone to miscarriage or premature delivery. |
Indisulam | Investigated for use/treatment in lung cancer. |
Aldesleukin | A recombinant analog of interleukin-2 used to induce an adaptive immune response in the treatment of renal cell carcinoma. |
Clonazepam | A long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, and seizures. |
Diazepam | A long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures. |
Flunitrazepam | For short-term treatment of severe insomnias, that are not responsive to other hypnotics. |
Nitrazepam | A long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, insomnia, and seizures. |
Ellagic acid | Ellagic acid is being investigated for use in follicular lymphoma, brain injury in intrauterine growth restricted babies, obese adolescents, and solar lentigines. |
Diacerein | For the treatment of osteoarthritis affecting the hip or knee . |
Safinamide | A MAO-B inhibitor used as an add-on treatment to levodopa/carbidopa for Parkinson's disease during "off" episodes. |
Azelastine | A histamine H1-receptor antagonist used intranasally to treat allergic and vasomotor rhinitis and in an ophthalmic solution to treat allergic conjunctivitis. |
Dexfenfluramine | For the management of obesity including weight loss and maintenance of weight loss in patients on a reduced calorie diet |
Methotrimeprazine | A phenothiazine used in the management of psychosis, particular those of schizophrenia, and manic phases of bipolar disorder. |
Vayarin | ADHD in children, hypertriglyceridemia [L1502, L1503]. |
Ditiocarb | A chelating agent that has been used to mobilize toxic metals from the tissues of man and experimental animals. It is the main metabolite of DISULFIRAM. |
Niacin | A B vitamin used to treat hypertriglyceridemia and pellagra. |
Orphenadrine | A muscarinic antagonist used as an adjunct for the symptomatic relief of musculoskeletal pain and discomfort. |
Osilodrostat | An oral inhibitor of cortisol synthesis used to treat Cushing's disease by normalizing hypercortisolism. |
Favipiravir | An antiviral used to manage influenza, and that has the potential to target other viral infections. |
Clascoterone | An androgen receptor antagonist used for the topical treatment of acne vulgaris in patients 12 years of age and older. |
Menadione | The primary known function of vitamin K is to assist in the normal clotting of blood, but it may also play a role in normal bone calcification. |
Rilpivirine | A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1). |
Ethambutol | An antituberculosis agent used in the prophylaxis and treatment of tuberculosis (TB). |