Increased Cellular Death

Increased Cellular Death
Accession Number

Not Available

DrugDrug Description
Ingenol mebutateA topical agent used for the treatment of actinic keratosis.
VenetoclaxA BCL-2 inhibitor used to treat chronic lymphocytic leukemia, small lymphocytic lymphoma, or acute myeloid leukemia.
Inotuzumab ozogamicinAn antibody-drug conjugate used to treat B-cell precursor acute lymphoblastic leukemia (ALL).
Drugs & Drug Targets
Ingenol mebutateProtein kinase C delta typetarget
Ingenol mebutateProtein kinase C alpha typetarget
VenetoclaxApoptosis regulator Bcl-2target
VenetoclaxCytochrome P450 3A4enzyme
VenetoclaxP-glycoprotein 1transporter
VenetoclaxATP-binding cassette sub-family G member 2transporter
VenetoclaxSolute carrier organic anion transporter family member 1B1transporter
Inotuzumab ozogamicinP-glycoprotein 1transporter
Inotuzumab ozogamicinB-cell receptor CD22target