Proteinogenic Amino Acids

Name
Proteinogenic Amino Acids
Accession Number
DBCAT005228
Description

There are 21 alpha-amino acids that are considered 'proteinogenic', meaning they are utilized in the biosynthesis of proteins. Nine of these amino acids - histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine - are 'essential' and cannot be produced endogenously.

Drugs
DrugDrug Description
ArginineAn amino acid commonly found as a component of total parenteral nutrition.
HistidineAn amino acid commonly found as a component of total parenteral nutrition.
LysineAn amino acid commonly found as a component of total parenteral nutrition.
Aspartic acidAn amino acid commonly found as a component in total parenteral nutrition.
Glutamic acidAn amino acid commonly found as a component in total parenteral nutrition.
SerineAn amino acid commonly found as a component in total parenteral nutrition.
ThreonineAn amino acid commonly found as a component of total parenteral nutrition.
AsparagineUsed for nutritional supplementation, also for treating dietary shortage or imbalance.
L-GlutamineAn amino acid commonly found as a component in total parenteral nutrition.
CysteineAn amino acid commonly found as a component of total parenteral nutrition and used as an antidote for acetaminophen overdose.
SelenocysteineA naturally occurring amino acid in both eukaryotic and prokaryotic organisms. It is found in tRNAs and in the catalytic site of some enzymes. The genes for glutathione peroxidase and...
GlycineAn amino acid commonly used as a component of total parenteral nutrition and is also used as irrigation during surgery.
ProlineAn amino acid commonly found as a component of total parenteral nutrition.
AlanineAn amino acid commonly found as a component of total parenteral nutrition.
IsoleucineAn amino acid commonly found as a component of total parenteral nutrition.
LeucineAn amino acid commonly found as a component of total parenteral nutrition.
MethionineAn amino acid commonly found as a component in total parenteral nutrition.
PhenylalanineAn amino acid commonly found as a component of total parenteral nutrition.
TryptophanAn amino acid commonly found as a component of total parenteral nutrition.
TyrosineAn amino acid commonly found as a component in total parenteral nutrition.
ValineAn amino acid commonly found as a component of total parenteral nutrition.
Drugs & Drug Targets
DrugTargetType
ArginineCationic amino acid transporter 3target
ArginineArginine decarboxylasetarget
ArginineArgininosuccinate lyasetarget
ArginineNitric oxide synthase, inducibletarget
ArginineHigh affinity cationic amino acid transporter 1target
ArginineArginase-2, mitochondrialtarget
ArginineCationic amino acid transporter 4target
ArginineArgininosuccinate synthasetarget
ArginineNitric oxide synthase, endothelialtarget
ArginineSolute carrier family 22 member 5transporter
ArginineMonocarboxylate transporter 10transporter
ArginineSolute carrier family 22 member 4transporter
HistidineHistidine decarboxylasetarget
HistidineHistidine--tRNA ligase, cytoplasmictarget
HistidineSodium-coupled neutral amino acid transporter 3target
HistidineHistidine ammonia-lyasetarget
HistidineMonocarboxylate transporter 10transporter
LysineHigh affinity cationic amino acid transporter 1target
LysineCationic amino acid transporter 4target
LysineCationic amino acid transporter 3target
LysineLow affinity cationic amino acid transporter 2target
LysineLysine--tRNA ligasetarget
LysineMonocarboxylate transporter 10transporter
LysineSolute carrier family 22 member 4transporter
Aspartic acidCalcium-binding mitochondrial carrier protein Aralar2target
Aspartic acidAspartate aminotransferase, cytoplasmictarget
Aspartic acidAspartoacylasetarget
Aspartic acidAsparagine synthetase [glutamine-hydrolyzing]target
Aspartic acidArgininosuccinate synthasetarget
Aspartic acidAminoacylase-1target
Aspartic acidAspartate aminotransferase, mitochondrialtarget
Aspartic acidAspartate--tRNA ligase, cytoplasmictarget
Aspartic acidCalcium-binding mitochondrial carrier protein Aralar1target
Aspartic acidAspartyl/asparaginyl beta-hydroxylasetarget
Aspartic acidMultifunctional protein ADE2target
Aspartic acidAdenylosuccinate synthetase isozyme 2target
Aspartic acidExcitatory amino acid transporter 3target
Aspartic acidArgininosuccinate synthetase, isoform CRA_atarget
Aspartic acidAspartate--tRNA ligase, mitochondrialtarget
Aspartic acidIsoaspartyl peptidase/L-asparaginasetarget
Aspartic acidRibonuclease pancreatictarget
Aspartic acidLysozyme Ctarget
Aspartic acidMonocarboxylate transporter 10transporter
Aspartic acidCAD proteinenzyme
Aspartic acidAdenylosuccinate Synthetasestarget
Glutamic acidGlutamate dehydrogenase 1, mitochondrialtarget
Glutamic acidGlutamate receptor ionotropic, kainate 1target
Glutamic acidGlutamate receptor 1target
Glutamic acidGlutamate--cysteine ligase regulatory subunittarget
Glutamic acidGlutamate carboxypeptidase 2target
Glutamic acidGlutamate decarboxylase 2target
Glutamic acidGlutamate decarboxylase 1target
Glutamic acidFormimidoyltransferase-cyclodeaminasetarget
Glutamic acidGlutamate receptor 2target
Glutamic acidGlutamate receptor 3target
Glutamic acidGlutamate receptor 4target
Glutamic acidDelta-1-pyrroline-5-carboxylate synthasetarget
Glutamic acidGlutamate receptor ionotropic, kainate 2target
Glutamic acidGlutamate receptor ionotropic, kainate 3target
Glutamic acidMetabotropic glutamate receptor 1target
Glutamic acidMetabotropic glutamate receptor 4target
Glutamic acidGlutamate receptor ionotropic, kainate 4target
Glutamic acidGlutamate receptor ionotropic, kainate 5target
Glutamic acidMetabotropic glutamate receptor 7target
Glutamic acidMetabotropic glutamate receptor 8target
Glutamic acidExcitatory amino acid transporter 5target
Glutamic acid5-oxoprolinasetarget
Glutamic acidPhosphoribosylformylglycinamidine synthasetarget
Glutamic acidBranched-chain-amino-acid aminotransferase, mitochondrialtarget
Glutamic acidGlutamate receptor ionotropic, NMDA 2Dtarget
Glutamic acidGlutaminase kidney isoform, mitochondrialtarget
Glutamic acidAspartate aminotransferase, mitochondrialtarget
Glutamic acidBifunctional glutamate/proline--tRNA ligasetarget
Glutamic acidAsparagine synthetase [glutamine-hydrolyzing]target
Glutamic acidGlutamine synthetasetarget
Glutamic acidAspartate aminotransferase, cytoplasmictarget
Glutamic acidTyrosine aminotransferasetarget
Glutamic acidAlanine aminotransferase 1target
Glutamic acidVitamin K-dependent gamma-carboxylasetarget
Glutamic acidExcitatory amino acid transporter 1target
Glutamic acidExcitatory amino acid transporter 2target
Glutamic acidExcitatory amino acid transporter 3target
Glutamic acidGlutamate--cysteine ligase catalytic subunittarget
Glutamic acidExcitatory amino acid transporter 4target
Glutamic acidGlutamate dehydrogenase 2, mitochondrialtarget
Glutamic acidGMP synthase [glutamine-hydrolyzing]target
Glutamic acidBranched-chain-amino-acid aminotransferase, cytosolictarget
Glutamic acid4-aminobutyrate aminotransferase, mitochondrialtarget
Glutamic acidGlutamate receptor ionotropic, NMDA 1target
Glutamic acidFolylpolyglutamate synthase, mitochondrialtarget
Glutamic acidGlutamyl aminopeptidasetarget
Glutamic acidGlutamate receptor ionotropic, NMDA 2Atarget
Glutamic acidGlutamate receptor ionotropic, NMDA 2Btarget
Glutamic acidGlutamate receptor ionotropic, NMDA 2Ctarget
Glutamic acidAspartate aminotransferasetarget
Glutamic acidProbable glutamate--tRNA ligase, mitochondrialtarget
Glutamic acidGlutamine-dependent NAD(+) synthetasetarget
Glutamic acidN-acetylglutamate synthase, mitochondrialtarget
Glutamic acidKynurenine/alpha-aminoadipate aminotransferase, mitochondrialtarget
Glutamic acidGlutamate receptor ionotropic, NMDA 3Atarget
Glutamic acidAlanine aminotransferase 2target
Glutamic acidAlpha-aminoadipic semialdehyde synthase, mitochondrialtarget
Glutamic acidGlutaminase liver isoform, mitochondrialtarget
Glutamic acidAspartyl aminopeptidasetarget
Glutamic acidCystine/glutamate transportertarget
Glutamic acidCarboxypeptidase Qtarget
Glutamic acidPhosphoserine aminotransferasetarget
Glutamic acidMonocarboxylate transporter 10transporter
Glutamic acidMonocarboxylate transporter 1transporter
Glutamic acidMitochondrial glutamate carrier 2transporter
Glutamic acidMitochondrial glutamate carrier 1transporter
SerineCystathionine beta-synthasetarget
SerineL-serine dehydratase/L-threonine deaminasetarget
SerineSerine racemasetarget
SerineSerine palmitoyltransferase 2target
SerineSerine palmitoyltransferase 1target
SerineSerine--tRNA ligase, cytoplasmictarget
SerineSerine--pyruvate aminotransferasetarget
SerineMonocarboxylate transporter 10transporter
ThreonineThreonine--tRNA ligase, cytoplasmictarget
ThreonineThreonine--tRNA ligase, mitochondrialtarget
ThreonineMonocarboxylate transporter 10transporter
AsparagineNeutral amino acid transporter B(0)target
AsparagineAsparagine synthetase [glutamine-hydrolyzing]target
AsparagineAsparagine--tRNA ligase, cytoplasmictarget
AsparagineIsoaspartyl peptidase/L-asparaginasetarget
AsparagineProbable asparagine--tRNA ligase, mitochondrialtarget
AsparagineMonocarboxylate transporter 10transporter
AsparagineSodium-coupled neutral amino acid transporterstarget
L-GlutamineCTP synthase 1target
L-GlutamineAmidophosphoribosyltransferasetarget
L-GlutamineGlutamine synthetasetarget
L-GlutamineMonocarboxylate transporter 10transporter
L-GlutamineCoagulation factor XIII A chainenzyme
L-GlutamineGlutaminase kidney isoform, mitochondrialenzyme
L-GlutamineGlutaminase liver isoform, mitochondrialenzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase 2enzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase 5enzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase 6enzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase Kenzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase 4enzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase Eenzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase Zenzyme
L-GlutamineSodium-coupled neutral amino acid transporter 3transporter
L-GlutamineNeutral amino acid transporter B(0)transporter
L-GlutamineGMP synthase [glutamine-hydrolyzing]enzyme
L-GlutamineAsparagine synthetase [glutamine-hydrolyzing]enzyme
L-GlutamineKynurenine--oxoglutarate transaminase 1enzyme
L-GlutaminePhosphoribosylformylglycinamidine synthaseenzyme
L-GlutamineGlutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrialenzyme
L-GlutamineGlutamine--fructose-6-phosphate aminotransferase [isomerizing] 2enzyme
L-GlutamineCAD proteinenzyme
L-GlutamineGlutamine--tRNA ligaseenzyme
L-GlutamineGlutamine-dependent NAD(+) synthetaseenzyme
L-GlutamineLarge neutral amino acids transporter small subunit 2transporter
L-GlutamineSodium-coupled neutral amino acid transporter 1transporter
L-GlutamineSodium-coupled neutral amino acid transporter 2transporter
L-GlutamineSodium- and chloride-dependent neutral and basic amino acid transporter B(0+)transporter
L-GlutamineY+L amino acid transporter 1transporter
L-GlutamineY+L amino acid transporter 2transporter
L-GlutamineLarge neutral amino acids transporter small subunit 1transporter
L-GlutamineB(0,+)-type amino acid transporter 1transporter
CysteineCysteine--tRNA ligase, cytoplasmictarget
CysteineGlutamate--cysteine ligase regulatory subunittarget
CysteineGlutamate--cysteine ligase catalytic subunittarget
CysteineAspartate aminotransferase, cytoplasmictarget
CysteineCystathionine gamma-lyasetarget
CysteineCystathionine beta-synthasetarget
CysteineCysteine dioxygenase type 1target
CysteineMethylated-DNA--protein-cysteine methyltransferasetarget
CysteineGlutathione synthetasetarget
CysteineProbable cysteine--tRNA ligase, mitochondrialtarget
CysteineCysteine sulfinic acid decarboxylasetarget
CysteineCysteine desulfurase, mitochondrialtarget
CysteineMonocarboxylate transporter 10transporter
CysteineAspartate aminotransferase, mitochondrialtarget
SelenocysteineCathelicidin antimicrobial peptidetarget
SelenocysteineNucleoside diphosphate kinase Atarget
SelenocysteineFormate dehydrogenase Htarget
SelenocysteineCysteine desulfurasetarget
GlycineGlutathione synthetasetarget
GlycineGlycine receptor subunit alpha-1target
GlycineSerine--pyruvate aminotransferasetarget
GlycineGlycine receptor subunit betatarget
GlycineSerine hydroxymethyltransferase, cytosolictarget
GlycineGlycine receptor subunit alpha-3target
GlycineGlycine receptor subunit alpha-2target
GlycineGlycine N-methyltransferasetarget
GlycineGlycine amidinotransferase, mitochondrialtarget
GlycineGlutamate receptor ionotropic, NMDA 3Btarget
Glycine2-amino-3-ketobutyrate coenzyme A ligase, mitochondrialtarget
Glycine5-aminolevulinate synthase, nonspecific, mitochondrialtarget
Glycine5-aminolevulinate synthase, erythroid-specific, mitochondrialtarget
GlycineGlycine--tRNA ligasetarget
GlycineGlutamate receptor ionotropic, NMDA 2Atarget
GlycineBile acid-CoA:amino acid N-acyltransferasetarget
GlycineN-arachidonyl glycine receptortarget
GlycineGlutamate receptor ionotropic, NMDA 2Ctarget
GlycineSerine hydroxymethyltransferasetarget
GlycineGlycine N-acyltransferasetarget
GlycineSerine hydroxymethyltransferase, mitochondrialtarget
GlycineGlycine N-acyltransferase-like protein 2target
GlycineGlycine N-acyltransferase-like protein 1target
GlycineAlanine--glyoxylate aminotransferase 2, mitochondrialtarget
GlycinePeroxisomal sarcosine oxidasetarget
GlycineMonocarboxylate transporter 10transporter
GlycineProton-coupled amino acid transporter 1transporter
GlycineVesicular inhibitory amino acid transportertransporter
GlycineSodium- and chloride-dependent glycine transporter 2transporter
GlycineSodium- and chloride-dependent glycine transporter 1transporter
GlycineAminomethyltransferase, mitochondrialenzyme
GlycineGlycine dehydrogenase [decarboxylating], mitochondrialenzyme
GlycineDihydrolipoyl dehydrogenase, mitochondrialenzyme
GlycineGlycine cleavage system H protein, mitochondrialenzyme
ProlinePyrroline-5-carboxylate reductase 1, mitochondrialtarget
ProlineBifunctional glutamate/proline--tRNA ligasetarget
ProlineSodium- and chloride-dependent neutral and basic amino acid transporter B(0+)target
ProlineSodium-dependent proline transportertarget
ProlinePyrroline-5-carboxylate reductase 2target
ProlineProlyl 4-hydroxylase subunit alpha-2target
ProlineProline dehydrogenase 1, mitochondrialtarget
ProlinePeptidyl-prolyl cis-trans isomerase Htarget
ProlineProline synthase co-transcribed bacterial homolog proteintarget
ProlineProlyl 4-hydroxylase subunit alpha-1target
ProlinePeptidyl-prolyl cis-trans isomerase Btarget
ProlinePeptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
ProlinePeptidyl-prolyl cis-trans isomerase Ctarget
ProlinePeptidyl-prolyl cis-trans isomerase Atarget
ProlinePeptidyl-prolyl cis-trans isomerase Gtarget
ProlineProlyl 3-hydroxylase 1target
ProlinePyrroline-5-carboxylate reductasetarget
ProlineProbable proline--tRNA ligase, mitochondrialtarget
ProlineProlyl 3-hydroxylase 2target
ProlineProlyl 3-hydroxylase 3target
ProlinePyrroline-5-carboxylate reductase 3target
ProlineTrans-L-3-hydroxyproline dehydratasetarget
ProlineProline dehydrogenase 1, mitochondrialenzyme
ProlineMonocarboxylate transporter 10transporter
AlanineSerine--pyruvate aminotransferasetarget
AlanineAlanine aminotransferase 1target
AlanineCysteine desulfurase, mitochondrialtarget
AlanineProton-coupled amino acid transporter 1target
AlanineLarge neutral amino acids transporter small subunit 2target
AlanineAlanine--glyoxylate aminotransferase 2, mitochondrialtarget
AlanineAlanine--tRNA ligase, cytoplasmictarget
AlanineNeutral amino acid transporter Atarget
Alanine4-aminobutyrate aminotransferase, mitochondrialtarget
AlanineKynureninasetarget
AlanineAlanine--tRNA ligase, mitochondrialtarget
Alanine5-phosphohydroxy-L-lysine phospho-lyasetarget
AlanineAlanine aminotransferase 2target
AlanineMonocarboxylate transporter 10transporter
IsoleucineShort/branched chain specific acyl-CoA dehydrogenase, mitochondrialtarget
IsoleucineBranched-chain-amino-acid aminotransferase, cytosolictarget
IsoleucineBranched-chain-amino-acid aminotransferase, mitochondrialtarget
IsoleucineIsoleucine--tRNA ligase, cytoplasmictarget
IsoleucineIsoleucine--tRNA ligase, mitochondrialtarget
IsoleucineMonocarboxylate transporter 10transporter
LeucineProbable leucine--tRNA ligase, mitochondrialtarget
LeucineLeucine carboxyl methyltransferase 2target
LeucineLeucine carboxyl methyltransferase 1target
LeucineLeucine--tRNA ligase, cytoplasmictarget
LeucineBranched-chain-amino-acid aminotransferase, mitochondrialtarget
LeucineBranched-chain-amino-acid aminotransferase, cytosolictarget
LeucineMonocarboxylate transporter 10transporter
LeucineMonocarboxylate transporter 8transporter
MethionineMethionine synthase reductasetarget
MethionineMethionine synthasetarget
MethionineMethionine aminopeptidase 2target
MethionineBetaine--homocysteine S-methyltransferase 1target
MethionineS-methylmethionine--homocysteine S-methyltransferase BHMT2target
MethionineGlutamine synthetaseenzyme
MethionineMethylenetetrahydrofolate reductaseenzyme
MethionineMonocarboxylate transporter 10transporter
MethionineS-adenosylmethionine synthase isoform type-2enzyme
MethionineMethionine-R-sulfoxide reductase B2, mitochondrialenzyme
MethionineS-adenosylmethionine synthase isoform type-1enzyme
MethionineMethionine-R-sulfoxide reductase B1enzyme
MethionineMitochondrial peptide methionine sulfoxide reductaseenzyme
MethionineMethionine--tRNA ligase, cytoplasmicenzyme
MethionineMethionine--tRNA ligase, mitochondrialenzyme
MethionineMethionine adenosyltransferase 2 subunit betaenzyme
MethionineS-methylmethionine--homocysteine S-methyltransferase BHMT2enzyme
PhenylalanineTyrosine aminotransferasetarget
PhenylalanineLarge neutral amino acids transporter small subunit 2target
PhenylalaninePhenylalanine--tRNA ligase alpha subunittarget
PhenylalaninePhenylalanine-4-hydroxylasetarget
PhenylalaninePhenylalanine--tRNA ligase, mitochondrialtarget
PhenylalaninePhenylalanine--tRNA ligase beta subunittarget
PhenylalanineTyrosine 3-monooxygenasetarget
PhenylalanineMonocarboxylate transporter 10transporter
TryptophanTryptophan--tRNA ligase, cytoplasmictarget
TryptophanTryptophan--tRNA ligasetarget
TryptophanTryptophan--tRNA ligase, mitochondrialtarget
TryptophanTryptophan 2,3-dioxygenaseenzyme
TryptophanAromatic-L-amino-acid decarboxylaseenzyme
TryptophanMonocarboxylate transporter 8transporter
TryptophanMonocarboxylate transporter 10transporter
TryptophanTryptophan--tRNA ligaseenzyme
TryptophanTryptophan--tRNA ligase, mitochondrialenzyme
TryptophanTryptophan 5-hydroxylase 1enzyme
TryptophanTryptophan 5-hydroxylase 2enzyme
TryptophanTryptophan--tRNA ligase, cytoplasmicenzyme
TryptophanIndoleamine 2,3-dioxygenase 1enzyme
TyrosineTyrosine 3-monooxygenasetarget
TyrosineTyrosine--tRNA ligase, mitochondrialtarget
TyrosineTyrosine--tRNA ligase, cytoplasmictarget
TyrosineTyrosine aminotransferasetarget
TyrosineMonocarboxylate transporter 8transporter
TyrosineMonocarboxylate transporter 10transporter
ValinePropionyl-CoA carboxylase beta chain, mitochondrialtarget
ValineBranched-chain-amino-acid aminotransferase, cytosolictarget
ValineValine--tRNA ligasetarget
ValineMonocarboxylate transporter 10transporter
ValineValine--tRNA ligaseenzyme
ValinePropionyl-CoA carboxylase beta chain, mitochondrialenzyme
ValineBranched-chain-amino-acid aminotransferase, cytosolicenzyme