Cholestasis (DBCOND0013207)

Identifiers

Synonyms
Obstruction of bile duct / Bile duct obstruction / Obstruction of bile duct (disorder) / Bile duct obstruction NOS / Occlusion of bile duct (disorder) / Biliary stasis / Cholestasis (finding)

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06604923
PET/CT Scans Using the Tracer 11C-Csar, a Bile Acid Analog, to Depict and Visualize Changes in the Hepatobiliary System in Patients With Primary Biliary Cholangitis Before and After Treatment.No drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT06610695
PET/CT Scans Using the Tracer 11C-Csar, a Bile Acid Analog, to Depict and Visualize Cholestatic Disorders in Patients with Genetic Liver Disorders and Healthy IndividualsNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT04510090
Evaluate the Safety, Tolerability, and PK of EP547 in Healthy Subjects and Subjects With Cholestatic or Uremic PruritusNo drug interventionstreatment1completed
NCT01073202
Effects of Ursodeoxycholic Acid on Graft Recovery Early After Adult Liver TransplantationtreatmentNot Availablecompleted
NCT00007033
Study of Magnesium Sulfate in Children With Reduced Bone Density Secondary to Chronic Cholestatic Liver DiseasetreatmentNot Availablecompleted
NCT02370251
Compassionate Use of Omegaven in Childrentreatment2 / 3completed
NCT02922751
FibroScan™ in Pediatric Cholestatic Liver Disease (FORCE)No drug interventionsNot AvailableNot Availablecompleted
NCT00392977
Brain Manganese Deposition in High Risk NeonatesNo drug interventionsNot AvailableNot Availablecompleted
NCT02778698
Compassionate Use of OmegavenNo drug interventionsNot AvailableNot Availableapproved_for_marketing
NCT02780193
Intravenous Fish Oils in the Treatment of Parenteral Nutrition Liver InjuryNot AvailableNot Availableapproved_for_marketing
NCT01062815
Prevention of Parenteral Nutrition-Associated Cholestasis With Cyclic Parenteral Nutrition in InfantsNo drug interventionspreventionNot Availableterminated
NCT00004315
Phase II Pilot Study to Compare the Bioavailability of Buffered, Enteric-Coated Ursodiol With Unmodified Ursodiol for Chronic Cholestatic Liver Disease and Cystic Fibrosis-Associated Liver Diseasetreatment2unknown_status
NCT04604652
Open-Label Study of HTD1801 in Adult Subjects With Primary Biliary CholangitisNo drug interventionstreatment2completed
NCT05718349
FGF19 in Obstructive Cholestasis: "Unveil the Signal"No drug interventionsNot AvailableNot Availablerecruiting
NCT00080236
Safety and Efficacy Study of a Caspase Inhibitor in Patients Undergoing Liver Transplantationtreatment2completed
NCT02966834
Dose Response Study of GSK2330672 for the Treatment of Pruritus in Participants With Primary Biliary Cholangitistreatment2completed
NCT04167358
Linerixibat Long-term Safety, and Tolerability Studytreatment3recruiting
NCT00816348
Compassionate Use of Omegaven IV Fat Emulsiontreatment2terminated
NCT02767648
Inter-regional Cohort of Neonatal and Infant Cholestasis in the Greater Southwest RegionNo drug interventionsNot AvailableNot Availableterminated
NCT02412566
SMOF Lipid for Children With Parenteral Nutrition Induced Liver InjuryNot AvailableNot Availableavailable
NCT03337074
Paternally Inherited Phenotypes in CholestasisNo drug interventionsNot AvailableNot Availableunknown_status
NCT00826020
Evaluation of Omegaven™ Parenteral Nutrition in Patients With Total Parenteral Nutrition (TPN)-Induced Cholestasistreatment2completed
NCT00007020
Compassionate Treatment of Patients With Inborn Errors of Bile Acid Metabolism With Cholic Acidtreatment3completed
NCT01998620
Efficacy and Safety of S-adenosyl-L-methionine in Treatment of Chronic Hepatitis B Patients With Cholestasistreatment4unknown_status
NCT03662282
Omegaven as Alternative Parenteral Fat Nutritiontreatment3completed
NCT04309773
Efficacy of 24 Month of Bezafibrate in Primary Sclerosing Cholangitis With Persistent Cholestasis Despite Ursodeoxycholic Acid Therapytreatment3recruiting
NCT00512629
Cholestasis Prevention: Efficacy of IV Fish Oilprevention1completed
NCT00135044
A Trial of Taurine Supplementation in Parenteral Nutrition 1No drug interventionspreventionNot Availableunknown_status
NCT06005701
Mallampati Score for Prediction and Prognosis of Postoperative Mortality and Morbidity and Safety Profiles of Patients Undergoing Laparoscopic Cholecystectomy in Qassim RegionNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00738101
Compassionate Use of an Intravenous Fish Oil Emulsion in the Treatment of Liver Injury in InfantstreatmentNot Availablecompleted
NCT02148146
Use of Omega 3 Oil Emulsion for Parenteral Nutrition Associated CholestasisNot AvailableNot Availableno_longer_available
NCT03992014
Pharmacokinetics (PKs) and Metabolism of Radiolabelled Linerixibattreatment1completed
NCT01252043
Retrospective Review of CT and MR in Pediatric Patients With CholestasisNo drug interventionsNot AvailableNot Availableunknown_status
NCT00058890
Gabapentin to Treat Itch in Patients With Liver Diseasetreatment3completed
NCT01297933
Compassionate Use of Omegaven for Pediatric Patients With Parenteral Nutrition Associated Liver DiseaseNot AvailableNot Availableapproved_for_marketing
NCT02663453
Effectiveness of Multicomponent Lipid Emulsion in Preterm Infants Requiring Parenteral Nutritiontreatment3completed
NCT02721277
SMOFlipid to Lessen the Severity of Neonatal Cholestasissupportive_care1 / 2terminated
NCT05582447
Osmotic Fragility in Red Blood Cells of Pediatric Patients With Cholestatic Liver DiseaseNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02477345
Compassionate Use of Omegaven IV Fat EmulsionNot AvailableNot Availableno_longer_available
NCT02334293
Omegaven® as Parenteral NutritiontreatmentNot Availableunknown_status
NCT01164878
Cholestasis in Extreme Low Birth Weight Infants (ELBW)No drug interventionsNot AvailableNot Availablecompleted
NCT02267707
Pharmacokinetic and Safety Study of Nab®-Paclitaxel (ABI-007) Plus Gemcitabine in Subjects With Advanced Pancreatic Cancer Who Have Cholestatic Hyperbilirubinemiatreatment1terminated
NCT00969332
A Safety and Efficacy Study to Determine if Giving Intravenous Fish Oil Helps Children With Liver Diseasetreatment2terminated
NCT01173159
Compassionate Use of Omegaven to Reverse Parenteral Nutrition Induced CholestasistreatmentNot Availablecompleted
NCT01373918
Low Dose Fat for the Prevention of Liver Disease in Babies With Gastrointestinal Disordersprevention4terminated
NCT01739517
Efficacy and Safety of Omega-3 Lipid Therapy in Pediatric Patients With Parenteral Nutrition-Associated Liver Diseasetreatment2unknown_status
NCT02420496
Enteral Fish Oil is Superior to Ursodeoxycholic Acid (UDCA) and Placebo for the Treatment of Cholestasis in Infantstreatment2withdrawn
NCT02936596
Remission Induction of Primary Biliary Cholangitis-autoimmune Hepatitis Overlap SyndrometreatmentNot Availableunknown_status
NCT01879735
Biliary Excretion of Conjugated Bile Acids in Humans Measured by 11C-cholylsarcosine PET/CTbasic_science1completed
NCT01585935
Preventing Cholestasis Using SMOFLipid®prevention4completed
NCT00846963
Ursodiol for Treating Parenteral Nutrition Associated Cholestasis in Neonatestreatment2 / 3completed
NCT01194063
Use of Omegaven Fish Oil Emulsion for Parenteral Nutrition Associated Liver Disease in Infants and Childrentreatment3completed
NCT00685386
A Randomized Controlled Trial (RCT) of Carbon Dioxide Versus Air Insufflation During Endoscopic Retrograde Cholangiopancreatography (ERCP)No drug interventionssupportive_careNot Availablecompleted
NCT00392730
Neurodevelopment and Neuroimaging in Parenterally-fed Infants and Young ChildrenNo drug interventionsNot AvailableNot Availablecompleted
NCT02357576
Standard Lipid Therapy vs IVFE Minimization for Prevention of PNALDprevention3completed
NCT01683240
Prospective Multicenter Evaluation of a New Short-access-cholangioscope for Biliary Duct Strictures and Gall StonesNo drug interventionstreatmentNot Availablecompleted
NCT03072667
Omegaven for Compassionate Use in the Treatment of Parenteral Nutrition-Associated Liver DiseaseNot AvailableNot Availableapproved_for_marketing
NCT06364969
Investigation of the Pruritogens of Liver-related DiseasesNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT01247012
Minimization of IntraLipid Versus OmegavenNo drug interventionstreatment2 / 3unknown_status
NCT00004410
Randomized Study of Tauroursodeoxycholic Acid in Prophylactic Therapy of Total Parenteral Nutrition Associated Cholestasis in InfantstreatmentNot Availablecompleted
NCT02801981
Dose-escalation Study of GSK2330672 in Japanese Healthy Male VolunteersNo drug interventionstreatment1completed
NCT00004414
Sincalide (Cholecystokinin Octapeptide) Versus Placebo in Neonates at High Risk for Developing Parenteral Nutrition Associated CholestasistreatmentNot Availablecompleted
NCT04053023
Linerixibat and Obeticholic Acid Drug Interaction Study in Healthy Subjectstreatment1completed
NCT02917408
Retrospective Study About Primary Biliary Cholangitis During January 2001 to July 2016 at West China HospitalNo drug interventionsNot AvailableNot Availablecompleted