Dialysis Dependent Chronic Kidney Disease (DBCOND0115707)

Identifiers

Synonyms

Chronic Kidney Disease on Hemodialysis / Hemodialysis-dependent chronic kidney disease (HDD-CKD) / Hemodialysis-dependent chronic kidney disease / Chronic kidney disease, Dialysis / Dialysis-dependent Chronic Kidney Disease / Chronic Kidney Disease, Receiving Dialysis / Chronic kidney disease on dialysis / Chronic Kidney Diseases Patient on Dialysis

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Colestilan chloride	Colestilan is an ingredient in the EMA-withdrawn product BindRen.	No drug targets
Doxercalciferol	A synthetic vitamin D2 analog used to treat secondary hyperparathyroidism in patients with chronic kidney disease with or without therapy of dialysis.	Sterol 26-hydroxylase, mitochondrialenzyme Vitamin D3 receptortarget
Ferric cation	An iron supplement indicated in the treatment of iron deficiency anemia.	Serotransferrincarrier Iron(3+)-hydroxamate-binding protein FhuDtarget Integrin beta-3carrier Calreticulincarrier Transferrin receptor protein 1target
Ferric pyrophosphate	Ferric pyrophosphate is intended to be indicated for the treatment of iron loss or iron deficiency as a formulation with a milder gastrointestinal effect.[L1423, L1433] Iron deficiency appears when the...	Ferritin light chaintarget Hemoglobin subunit alphatarget Hemoglobin subunit betatarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT06588114	Arteriovenous Fistula Cannulation Pain and Skin Cooling Device	No drug interventions	prevention	Not Available	not_yet_recruiting
NCT02754986	Quantification of Autonomic Nervous Activity During Hemodialysis	No drug interventions	treatment	Not Available	completed
NCT00667576	Dose-response Study of Paricalcitol Injection in Chronic Kidney Disease Patients Receiving Hemodialysis	Maxacalcitol Paricalcitol	treatment	2	completed
NCT01736150	Dose-Titration Study of Sevelamer Carbonate in Chronic Kidney Disease (CKD) Patients on Hemodialysis	Sevelamer	treatment	3	completed
NCT06477978	The Prevalence of Sarcopenia in a Cohort of Haemodialysis Patients and Its Correlation With Mortality	No drug interventions	diagnostic	Not Available	completed
NCT03054350	Dose-Finding Study of Vadadustat in Japanese Subjects With Anemia Secondary to Dialysis-Dependent Chronic Kidney Disease (DD-CKD)	Vadadustat	treatment	2	completed
NCT03140722	Study to Evaluate Vadadustat for Anemia in Subjects With Dialysis-Dependent Chronic Kidney Disease (DD-CKD) Who Are Hyporesponsive to Erythropoiesis Stimulating Agents	Erythropoietin Vadadustat	treatment	2	terminated
NCT03799627	Study of Vadadustat in Hemodialysis Participants With Anemia Switching From Epoetin Alfa	Erythropoietin Vadadustat	treatment	2	completed
NCT03242967	Study to Evaluate Three Times Per Week (TIW) Oral Dosing of Vadadustat for Anemia in Subjects With Dialysis-Dependent Chronic Kidney Disease (DD-CKD)	Darbepoetin alfa Vadadustat	treatment	3	withdrawn
NCT02892149	Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Participants With Dialysis-dependent Chronic Kidney Disease (DD-CKD)	Darbepoetin alfa Vadadustat	treatment	3	completed
NCT02865850	Efficacy and Safety Study to Evaluate Vadadustat for the Correction or Maintenance Treatment of Anemia in Participants With Incident Dialysis-dependent Chronic Kidney Disease (DD-CKD)	Darbepoetin alfa Vadadustat	treatment	3	completed
NCT01890577	Study of South African Dialysis Patients	Darbepoetin alfa	Not Available	Not Available	terminated