Immunodeficiencies (DBCOND0039518)

Identifiers

Synonyms
Immunodeficiency / Immuno-Deficiency / Immune Deficiency / Immune Deficiencies / Immunodeficiency, unspecified / Immunodeficiency syndromes / Immunodeficiency NOS / Immunodeficiency disorder (disorder) / Unspecified immunity deficiency / Immunologic Deficiency Syndromes

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Pidotimod
A synthetic agent with immunomodulatory properties used in patients with documented cell-mediated immunosuppression to stimulate their immunity during lung and urinary tract infections.
No drug targets
Varicella zoster vaccine (recombinant)
Varicella zoster vaccine is indicated for the prevention of herpes zoster (HZ) (shingles) in adults aged 50 years and older and in adults aged 18 years and older who are...
No drug targets
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05907746
Allogeneic Hematopoietic Stem Cell Transplantation With JSP191-Based Conditioning in Participants With GATA2 Deficiencytreatment2recruiting
NCT06634641
Clozapine-related Immunodeficiency in Parkinson's DiseaseNo drug interventionstreatment4recruiting
NCT00001467
Genetic Analysis of Immune DisordersNo drug interventionsNot AvailableNot Availablerecruiting
NCT01861106
Allogeneic Hematopoietic Stem Cell Transplant for GATA2 Mutationstreatment2recruiting
NCT04408950
Sample Collection for Systems Evaluation of Patients With Unknown or Incompletely Characterized Immune DefectsNo drug interventionsNot AvailableNot Availablerecruiting
NCT05027945
A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrometreatment2recruiting
NCT05672654
Evaluation of Post-SARS-CoV-2 Vaccinal Response in Immunocompromised PatientsNo drug interventionsscreeningNot Availablewithdrawn
NCT06612515
Vaccine-induced Immunity in Immunocompromised PatientsNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT01800643
Evaluation of Plasmatic Levels of Busulfan in Patients Undergoing Hematopoietic Stem Cell TransplantationNo drug interventionstreatment2 / 3unknown_status
NCT03651245
European Alpha-Mannosidosis ParticipantNo drug interventionsNot AvailableNot Availableterminated
NCT04553705
Omega-3, Nigella Sativa, Indian Costus, Quinine, Anise Seed, Deglycyrrhizinated Licorice, Artemisinin, Febrifugine on Immunity of Patients With (COVID-19)treatment2 / 3completed
NCT06576024
Immunogenicity and Safety of Inactivated Hepatitis A Vaccine in HIV-infected PeopleNo drug interventionsprevention4recruiting
NCT03557463
Testing a Novel Dairy Protein to Counteract ImmunosenescenceNo drug interventionstreatmentNot Availablecompleted
NCT05587894
OPtimisation of Antiviral Therapy in Immunocompromised COVID-19 Patients: a Randomized Factorial Controlled Strategy Trialtreatment2recruiting
NCT02274662
Expanded Access Protocol Thymus Transplantationtreatment4completed
NCT00923364
Pilot and Feasibility Study of Reduced-Intensity Hematopoietic Stem Cell Transplant for MonoMACtreatment2completed
NCT01027702
Donor Lymphocyte Infusion After Alternative Donor TransplantationNo drug interventionstreatment1 / 2terminated
NCT04447937
Immunodeficiency in MSNo drug interventionsNot AvailableNot Availableunknown_status
NCT02345135
Susceptibility to Infections in Ataxia TelangiectasiaNo drug interventionssupportive_careNot Availablecompleted
NCT00925925
Epigenetic Markers of B-Cell Function in Low Birth Weight InfantsNo drug interventionsNot AvailableNot Availablecompleted
NCT06248957
SYSTEMS-LEVEL ANALYSES OF IMMUNE DYSREGULATIONNo drug interventionsNot AvailableNot Availablerecruiting
NCT03374566
Immunodeficiency for Severe Epstein-Barr Virus InfectionNo drug interventionsNot AvailableNot Availablecompleted
NCT02291965
Blood Samples to Identify Biomarkers of BusulfanNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02651376
Safety and Efficacy of Allogenic Adoptive Immune Therapy for Advanced AIDS PatientsNo drug interventionstreatment1 / 2completed
NCT05405491
Impact of a Strategy Based on Bacterial DNA Detection to Optimize Antibiotics in Immunocompromised Patients With Hospital-acquired Pneumonia Requiring Mechanical VentilationNo drug interventionstreatmentNot Availablerecruiting
NCT00758992
Peripheral Blood Stem Cells Obtained From Normal Volunteers for Studying Retroviral Vector Mediated Gene Transfer Into Primitive Hematopoietic Cells and Vector Mediated Transgene Expression in Mature Hematopoietic LineagesNo drug interventionsNot AvailableNot Availablecompleted
NCT05655546
ImmunoCARE: Rapid, Accurate COVID Testing to Reduce Hospitalization of Immunocompromised IndividualsNo drug interventionsotherNot Availableactive_not_recruiting
NCT05629247
Pediatric Intensive Care Unit and Primary Immune DeficiencyNo drug interventionsdiagnosticNot Availablecompleted
NCT03166449
Effects of Immunonutrition on Biomarkers in Traumatic Brain InjuryNo drug interventionstreatmentNot Availablecompleted
NCT04738812
Determination of Adequate Tuberculosis Regimen in Patients Hospitalized With HIV-associated Severe Immune SuppressionNo drug interventionstreatment3recruiting
NCT05461378
PREP (Pre-Exposure Prophylaxis) of COVID-19Not AvailableNot Availablecompleted
NCT04836260
Preemptive Use of Convalescent Plasma for High-risk Patients With COVID-19No drug interventionsprevention3unknown_status
NCT00001281
Studies of the Pathogenesis of HIV Infection in Human Peripheral Blood Cells and/or Body Fluids in People Living With and Without HIVNo drug interventionsNot AvailableNot Availablerecruiting
NCT04852276
COVID-19 Vaccination and Outcomes in Individuals With and Without Immune Deficiencies and DysregulationsNo drug interventionsNot AvailableNot Availablecompleted
NCT03145545
Expanded Access Protocol Using Alpha/Beta T and CD19+ Depleted PBSCNo drug interventionsNot AvailableNot Availableavailable
NCT01316549
Study of Fludarabine Drug Exposure in Pediatric Bone Marrow TransplantationNot AvailableNot Availablecompleted
NCT03609827
Study of Melphalan Drug Exposure in Pediatric Hematopoietic Stem Cell Transplant PatientsNot AvailableNot Availablecompleted
NCT01666080
Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)treatmentNot Availablerecruiting
NCT01050855
Reduced Intensity Conditioning (RIC) Regimen for Patients With Non-malignant Disorderstreatment2active_not_recruiting
NCT01049854
CD34+Selection for Partially Matched Family or Matched Unrelated Adult Donor Transplanttreatment2completed
NCT02356653
Expanded Access Protocol Using CD3+/CD19+ Depleted PBSCNo drug interventionstreatment0recruiting
NCT01793506
Novel Testing ProceduresNo drug interventionsNot AvailableNot Availablewithdrawn
NCT02990819
Alpha/Beta T and CD19+ Depleted Peripheral Stem Cells for Patients With Primary ImmunodeficienciesNo drug interventionstreatment2recruiting
NCT00579124
CHP 834 Unrelated and Partially Matched Related Donor Peripheral Stem Cell Transportation for T and B Cell DepletionNo drug interventionstreatment2completed
NCT01050439
Unrelated Donor Transplant for Malignant and Non-Malignant DisordersNo drug interventionstreatment2terminated
NCT02277639
Reduced Intensity Conditioning Using CD3+/CD19+ Depletion for Non Malignant Transplantable DiseasesNo drug interventionstreatment2completed
NCT00801931
Double Cord Blood Transplant for Patients With Malignant and Non-malignant Disorderstreatment1 / 2terminated
NCT00744692
Reduced Intensity Conditioning for Umbilical Cord Blood Transplant in Pediatric Patients With Non-Malignant Disorderstreatment1completed
NCT03609814
Study of Clofarabine and Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation (HCT)Not AvailableNot Availablecompleted
NCT00852943
Screening Protocol for Genetic Diseases of Allergic InflammationNo drug interventionsNot AvailableNot Availablecompleted
NCT03968211
Undetectable IgE as a Sentinel Biomarker for Humoral Immunodeficiencydiagnostic1completed
NCT02771600
Pilot Study of a New Device (Buzzy®) for Procedural Pain Relief During Needle-Related Procedures in Paediatric PatientsNo drug interventionssupportive_careNot Availablecompleted
NCT01200017
Expanded Access Protocol (EAP) Using the CliniMACS® Device for Pediatric Haplocompatible Donor Stem Cell TransplantNo drug interventionsNot AvailableNot Availableno_longer_available
NCT06332196
Immunodeficiency and Cancer: Identification of Congenital Immune System Defects Underlying Paediatric LymphomasNo drug interventionsdiagnosticNot Availablerecruiting
NCT03922958
Immunoparalysis in Acute Kidney Injury After Cardiac SurgeryNo drug interventionsNot AvailableNot Availableterminated
NCT04643639
Assessing the Effects of CytoSorb Hemoperfusion on the Development on ImmunoparalysisNo drug interventionstreatment3completed
NCT04646525
The Relationship Between Covid-19 Infection in Pediatric Patients and Secondary Lymphoid OrgansNo drug interventionsNot AvailableNot Availableunknown_status
NCT05421325
Efficacy of QBKPN Site-Specific Immunomodulator in Improving Innate Immune Function & Reducing Respiratory Tract Infection in Older AdultsNo drug interventionsprevention2recruiting
NCT03051425
Immune Benefits of Consumption of Dairy Yogurt in ElderlyNo drug interventionssupportive_careNot Availablecompleted
NCT03707782
Mechanisms of Immune DeficiencyNo drug interventionsNot AvailableNot Availableunknown_status
NCT05792891
Approaches and Metrics in Fraily Patients During COVID-19 EraNo drug interventionsNot AvailableNot Availablecompleted
NCT03899480
Adoptive Transfer of Haploidentical NK Cells and N-803treatment1completed
NCT03312244
Pyridostigmine as Immunomodulator in People Living With HIVtreatment2suspended
NCT03609840
Study of Thiotepa and TEPA Drug Exposure in Pediatric Hematopoietic Stem Cell Transplant PatientsNot AvailableNot Availablecompleted
NCT02895204
Effect of Fermented Maillard Reacted Whey Protein on Immune FunctionNo drug interventionssupportive_careNot Availablecompleted
NCT03721146
ENCAPSID Study : ENCApsulated Bacterial Infection and Primary, Secondary ImmunoDeficiencyNo drug interventionsNot AvailableNot Availableunknown_status
NCT02653495
Impact of Metabolic Syndrome on Flu Vaccine EfficacyNo drug interventionsbasic_scienceNot Availableterminated
NCT05605808
Aerobic Training and Diet on the Immune System in Postmastectomy Patients Receiving ChemotherapyNo drug interventionstreatmentNot Availablerecruiting
NCT02334943
Immune Activation in HIV-1 Infected Patients Under AntiRetroviral TreatmentNo drug interventionsdiagnosticNot Availablecompleted
NCT00968864
T-cell Depleted Alternative Donor TransplantationNo drug interventionstreatment2terminated
NCT02508584
Personalized Immunotherapeutic for Antibiotic-resistant InfectionNo drug interventionstreatment0completed
NCT01359384
Bronchial Inflammation in Patients With Severe Immune Deficiency Under Immunoglobulin TreatmentNo drug interventionsNot AvailableNot Availableunknown_status
NCT05256784
Mountain Food and Natural Probiotic in NutritionNot AvailableNot Availablecompleted
NCT04448951
Immune Homeostasis in Sepsis and Septic ShockNo drug interventionsNot AvailableNot Availablerecruiting
NCT04824651
Covid-19 Vaccine Cohort in Specific PopulationsNo drug interventionsNot AvailableNot Availableunknown_status
NCT04818177
Immunoglobulin G Therapy Dose OptimizationNo drug interventionsNot AvailableNot Availablerecruiting
NCT00527878
Effect of Ranitidine on Hyper-IgE Recurrent Infection (Job's) Syndrometreatment2terminated
NCT05584488
Allergy and Immunology Natural History StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT06278337
X-linked Moesin Associated ImmunodeficiencyNo drug interventionsNot AvailableNot Availablerecruiting
NCT04698759
Immune and Scfa Profile of Stunting ChildrenNo drug interventionsNot AvailableNot Availablecompleted
NCT04422418
Impact of Burnout on Cardiovascular and Immune Biomarkers in Healthcare Professionals - Covid-19 Pandemic in Abu DhabiNo drug interventionsNot AvailableNot Availableunknown_status
NCT03881566
Presepsin as Detective Marker of Sepsis in Immunodeficiency ICU PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT04979065
Nutrition, Immunity, and Covid-19 in Obese PeopleNo drug interventionsprevention2completed
NCT06089174
Assessment of the Increased Risk of Infection Following an UltratrailNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT03052491
Effects of a 10 Component Dietary Supplement on Health and the Quality of LifeNo drug interventionspreventionNot Availablecompleted
NCT04382508
Coronavirus Infection in Primary or Secondary Immunosuppressed Children and Adults.No drug interventionsNot AvailableNot Availableunknown_status
NCT00404560
Detection and Characterization of Infections and Infection SusceptibilityNo drug interventionsNot AvailableNot Availablerecruiting
NCT01881334
Expanded Access to T-cell Depleted Haplo-Identical Stem Cells for Patients Receiving Haplo-Identical and Unrelated Cord Blood TransplantsNo drug interventionsNot AvailableNot Availableavailable
NCT02660281
URMC Related Haplo-identical Donor BMTtreatment1completed